Here are the 10 Houston startups that closed venture capital investment in the fourth quarter of last year. Photo via Getty Images

Houston startups saw a busy last quarter when it came to funding in 2022. From seed to series C, 10 Houston startups wrapped up the year with investment round closings.

In case you missed some of these headlines, InnovationMap has rounded up these 10 deals based on previous reporting. Scroll through to see which Houston startups are catching the eyes — and cashing the checks — of investors.

Houston-based virtual reality startup raises $3.2M in first outside capital round

VR training startup, HTX Labs, has raised funding from an outside investor for the first time. Courtesy of HTX Labs

HTX Labs, a Houston-based company that designs extended reality training for military and business purposes, announced last week that it has raised its first outside capital.

The company has received a $3.2 million investment from Cypress Growth Capital. Founded in 2017, HTX Labs — developer of the EMPACT Immersive Learning Platform — has been granted funding from the Department of Defense as well as grown its client base of commercial Enterprises. The platform uses virtual and extended reality that "enables organizations to rapidly create, deploy, measure, and sustain cost-effective, secure, and centralized immersive training programs, all within engaging, fully interactive virtual environments," per a news release.

“We have been looking to secure outside capital to accelerate the growth of our EMPACT platform and customer base but we hadn’t found the right partner who provided an investment vehicle that matched our needs,“ says HTX Labs CEO Scott Schneider in the release. “We found everything we were looking for in Cypress Growth Capital. They have a non-dilutive funding model that aligns with our capital expectations and have the level of experience that really makes this smart money." Read more.

Houston-based travel tech startup raises nearly $1M to continue expansion

A Houston company has raised additional funding as it grows its encrypted lodging booking platform. Photo via Gustavo Fring/Pexels

A travel booking technology company that's looking to alleviate some of the stresses of finding and making hotel reservations has raised additional seed funding.

Houston-based Pinktada has raised additional funding to the tune of $975,000. Ireland-based Selenean Capital contributed to the seed funding round, joining the company's previous investor True Global Ventures 4 Plus, which has invested $2 million to date. According to Crunchbase data, the latest investment brings the company's total to $3.9 million.

“Selenean Capital’s approach to partnership is identifying real world future needs and then working relentlessly to achieve those goals," says Davin Browne, Selenean’s CEO, in a news release. "Pinktada encapsulates this perfectly with a transformational approach to the hotel booking model built around a brilliant team. We look forward to the partnership and journey with them." Read more.

Houston microgrid tech company announces $150 investment

Houston-based VoltaGrid provides small-scale, self-contained microgrids that can operate independently of major power grids or in tandem with other microgrids. Photo via voltagrid.com

VoltaGrid, a Bellaire-based startup that specializes in distributed power generation via microgrids, has hauled in $150 million in equity funding.

Founded in 2020, VoltaGrid provides small-scale, self-contained microgrids that can operate independently of major power grids or in tandem with other microgrids. VoltaGrid’s product consists of natural gas engines, portable energy storage, natural gas processing and grid power connectivity.

Investors in the $150 million round include the Canada Pension Plan Investment Board (CPP Investments), Longbow Capital, Walter Ventures, and Pilot Company (operator of more than 800 retail and fueling locations in the U.S. and Canada). The $150 million round comes less than a year after VoltaGrid announced a $100 million round featuring the same investors. Read more.

Houston SaaS company raises $15M series B, announces latest release

Houston-based GoCo.io has raised fresh funding and launched the latest version of its platform. Courtesy of GoCo

A Houston startup that is optimizing human resource operations for small businesses has raised fresh funding from an Austin-based venture capital investor.

GoCo.io raised $15 million in September in a funding round led by ATX Venture Partners. Founded in 2015, the company has raised $27.5 million to date, including its $7 million series A in 2019.

The fresh funding will be used to continue expanding on the company's software services operations and upgrades to its product, which is is modernizing HR, benefits, and payroll.

“We believe that GoCo is the company best positioned to provide HR departments at SMBs with the most flexible employee management software,” says Chris Shonk, general partner at ATX Venture Partners, in a news release. “In a crowded marketplace, GoCo clearly rises to the top with its ease-of-use, flexibility and unparalleled customization. Read more.

Houston tech startup raises $3.5M following industry expansion

Rivalry Tech's co-founders — Marshall Law and Aaron Knape — share news of the company's latest round of investment. Photo courtesy of Rivalry Tech

A Houston-based company that optimizes mobile ordering for large venues has closed its latest round of funding.

Rivalry Tech, originally founded as sEATz and tackling mobile ordering in sports venues, has raised $3.5 million following expanding with a new product, myEATz, that targets the health care, leisure, and business industries. The round was led by Houston-based Sightcast, with participation from Houston-based Softeq Venture Studio, Rice University’s Valhalla Investment Group, and more.

“Sightcast Capital Partners looks to invest in strong, founder-led companies that bring a forward-thinking solution to everyday problems," says Neal Simpson, managing partner of Sightcast Capital Partners, in a news release. "In Rivalry Tech, we saw a team that recognized an opportunity to streamline the way in which food and beverage transactions occur in the healthcare, leisure, sports, and entertainment markets. Their two-sided approach of using technology as a tool to increase vendor profitability and also positively influence consumer experience is what immediately attracted us to this opportunity." Read more.

Houston unicorn chemicals company raises $200M series D

Solugen closed its series D funding round at $200 million. Photo via Getty Images

Houston-based Solugen has announced its latest round of investment to the tune of $200 million. The company, which reached unicorn status after its $357 million series C round last year, uses its patented Bioforge processes to produce "green" chemicals from bio-based feedstocks.

"Solugen is reimagining the chemistry of everyday life with enzymes found in nature. We make chemicals better, faster, cheaper, and without fossil fuels from right here in Houston, Texas. Whether you care about the climate, local competitiveness, or just plain old profits, we have good news: it's working," the company states in its news release. Read more.

Houston company closes $76M series C round to fuel its mission of reducing carbon emissions

Syzygy Plasmonics has raised a series C round of funding. Photo courtesy of Syzygy

A Houston-based company that is electrifying chemical manufacturing has closed its largest round of funding to date.

Syzygy Plasmonics closed a $76 million series C financing round led by New York-based Carbon Direct Capital. The round included participation from Aramco Ventures, Chevron Technology Ventures, LOTTE CHEMICAL, and Toyota Ventures. The company's existing investors joining the round included EVOK Innovations, The Engine, Equinor Ventures, Goose Capital, Horizons Ventures, Pan American Energy, and Sumitomo Corporation of Americas. According to a news release, Carbon Direct Capital will join Syzygy's board and serve as the series C director.

"We were very attracted to the multiple use cases for the Syzygy reactor and the lifetime-value of each Syzygy customer," says Jonathan Goldberg, Carbon Direct Capital's CEO, in the release. "Emissions from hydrogen production total more than 900 million metric tons of carbon dioxide per year. Syzygy's photocatalysis technology is a key solution to decarbonize hydrogen production as well as other critical industries." Read more.

Houston SaaS startup raises $6M seed

Houston-based SynMax has closed its first round of funding. Photo via Getty Images

A Houston-based satellite data analytics company is celebrating an oversubscribed round of recent funding.

SynMax announced this week that it closed its seed round at $6 million with an oversubscription of $2 million. The startup is providing geospatial intelligence software as a service to customers within the energy and maritime industries. The technology combines earth observation imagery and key data sources for predictive analytics and artificial intelligence.

The company reports that all of the investment came from SynMax customers. The round was led by Houston-based Skylar Capital, an investment management firm focused on the natural gas market. Read more.

Houston health tech startup secures $27M in financing

A Houston startup that created a remote monitoring and care platform has raised millions in financing. Image via michealthcare.com

A virtual health care and analytics provider startup has closed its latest round of funding for a total of $27 million in financing.

Medical Informatics Corp. closed a $17 million series B co-led by Maryland-based Catalio Capital Management and California-based Intel Capital. The financing also includes an additional $10 million in debt led by Catalio through Catalio’s structured equity strategy, according to a news release.

“We are excited to have had this round co-led by Catalio and Intel Capital," says Emma Fauss, CEO and co-founder of MIC, in the release. "Catalio brings significant financial and technical resources, while Intel Capital possesses strong operational and industry experience, and we look forward to continuing to leverage both firms’ expertise as we continue to scale.” Read more.

Houston sportstech platform raises $1.3M seed round

This Houston startup has fresh funding to build out its data intelligence platform. Photo via aim7.com

How many times have you forced yourself to do an arduous workout when you just weren’t feeling it? Despite what some trainers will tell you, you probably didn’t feel any better after. Sports scientist Dr. Erik Korem could have told you that, but more importantly, so could his creation, AIM7.

Marketed as “the fastest, easiest way to change your habits and improve your health,” Korem just raised a $1.3 million seed round that will bring his ambitious app to consumers in its beta form early next month.

The data intelligence platform would know that on a day that you’re stressed, that Peloton tabata ride might not be in your best interest. How? “The data from your Apple Watch or your Fitbit is just data. ‘I walked 7000 steps or I slept 8 hours,’” explains Korem. “We are the recommendation engine that makes this usable for you.” Read more.

This week's roundup of Houston innovators includes Emma Fauss of Medical Informatics Corp., Anas Al Kassas of INOVUES, and Scott Blair of Popable. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health tech to energy efficiency — recently making headlines in Houston innovation.

Emma Fauss, CEO and co-founder of Medical Informatics Corp.

A Houston startup that created a remote monitoring and care platform has raised millions in financing. Image via michealthcare.com

Houston-based Medical Informatics Corp. closed a $17 million series B co-led by Maryland-based Catalio Capital Management and California-based Intel Capital. The financing also includes an additional $10 million in debt led by Catalio through Catalio’s structured equity strategy, according to a news release.

“We are excited to have had this round co-led by Catalio and Intel Capital," says Emma Fauss, CEO and co-founder of MIC, in the release. "Catalio brings significant financial and technical resources, while Intel Capital possesses strong operational and industry experience, and we look forward to continuing to leverage both firms’ expertise as we continue to scale.”

MIC created an FDA-cleared virtual care platform, called Sickbay, that gives health care providers and hospitals away to remotely monitor patients in any setting with vendor-neutral real-time medical device integration, workflow automation and standardization. Click here to read more.

Anas Al Kassas, founder and CEO of INOVUES

INOVUES Founder and CEO Anas Al Kassas joins the Houston Innovators Podcast to discuss how he’s moving the needle on the energy transition within the construction and architectural industries. Photo courtesy of INOVUES

An architect by trade, Anas Al Kassas says he was used to solving problems in his line of work. Each project architects take on requires building designers to be innovative and creative. A few years ago, Kassas took his problem-solving background into the entrepreneurship world to scale a process that allows for retrofitting window facades for energy efficiency.

“If you look at buildings today, they are the largest energy-consuming sector — more than industrial and more than transportation,” Kassas, founder and CEO of INOVUES, says on the Houston Innovators Podcast. “They account for up to 40 percent of energy consumption and carbon emissions.”

To meet their climate goals, companies within the built environment are making moves to transition to electric systems. This has to be done with energy efficiency in mind, otherwise it will result in grid instability.

"Energy efficiency goes hand in hand with energy transition," he explains. Read more.

Scott Blair, CEO and co-founder of Popable

Walmart and Popable are teaming up just in time for the holiday shopping season. Image courtesy of Popable

With the holidays in full swing, and small businesses looking to gain back revenues lost during the COVID-19 pandemic, Walmart and Houston-based Popable are providing the opportunity to display and sell their products at Walmart can be highly beneficial to recoup profits, and unload new and extra products to a larger audience.

“Going into the holidays the timing is pretty good for a lot of brands looking to move some access inventory that they have loaded up from last year, but this (hopefully with Walmart) will be a year-round thing,” says Popable CEO and co-founder Scott Blair. “The pop-up opportunities we’ve been seeing with brands doing reach outs so far, a lot of them are looking for stuff into January and February too.”

Popable has assisted brands secure qualified spaces, get education and resources, and build community, and connections that are vital to helping small businesses expand their visibility in the marketplace. The platform simultaneously helps retail landlords find qualified retailers from a directory of tens of thousands of brands to fill vacancies and drive traffic to their shopping centers. Read more.

A Houston startup that created a remote monitoring and care platform has raised millions in financing. Image via michealthcare.com

Houston health tech startup secures $27M in financing

money moves

A virtual health care and analytics provider startup has closed its latest round of funding for a total of $27 million in financing.

Medical Informatics Corp. closed a $17 million series B co-led by Maryland-based Catalio Capital Management and California-based Intel Capital. The financing also includes an additional $10 million in debt led by Catalio through Catalio’s structured equity strategy, according to a news release.

“We are excited to have had this round co-led by Catalio and Intel Capital," says Emma Fauss, CEO and co-founder of MIC, in the release. "Catalio brings significant financial and technical resources, while Intel Capital possesses strong operational and industry experience, and we look forward to continuing to leverage both firms’ expertise as we continue to scale.”

MIC created an FDA-cleared virtual care platform, called Sickbay, that gives health care providers and hospitals away to remotely monitor patients in any setting with vendor-neutral real-time medical device integration, workflow automation and standardization.

“We have seen an increased demand for our solution as our clients face significant staffing challenges and are looking for ways to amplify and empower their workforce," Fauss says in the release. "Some of the largest health care systems in the country are standardizing their infrastructure on our Sickbay platform while consolidating IT spend."

Other participants in the round included new investors TGH Innoventures, Tampa General Hospital’s innovation center and venture fund, and Austin-based Notley — as well as existing investors San Francisco-based DCVC, the Texas Medical Center, and nCourage, a Houston-based investment group.

As a part of the round, two individuals from Catalio will join the board at MIC. Jonathan Blankfein, principal at Catalio will join the board of directors, Diamantis Xylas, head of research at Catalio, will join as board observer.

“Health care systems’ need for high-caliber, cost-saving, data-driven technology is only going to increase, and MIC’s proprietary platform is perfectly positioned to address some of the most critical clinical challenges that health care organizations face,” says Blankfein in the release. “We look forward to continuing to support MIC’s strong team as it continues to deliver better outcomes for health care organizations and patients alike.”

Amid the pandemic and the rising need for remote care technology, MIC scaled rapidly in the past two years. The company will use the funding to continue fueling its growth, including hiring specialized talent — deep product specialists and client engagement teams — to support long-term strategic partnerships.

“One of the main barriers to advanced analytics in health care is the siloing of data and today there is a significant need for a platform to enable flexible, centralized and remote monitoring at scale and on demand,” says Mark Rostick, vice president and senior managing director at Intel Capital, in the release. “Medical Informatics is setting a new standard of health care by removing these data silos for health care providers of all sizes and transforming the way patients are monitored from hospital to home with real-time AI.”

The five finalists in the Top Founder Under 40 category for the inaugural InnovationMap Awards share the challenges they have had to overcome. Photos courtesy

Overheard: Young founders explain the challenges they've faced

Eavesdropping in houston

It's not easy being the youngest person in a room, and that's certainly the case for startup founders looking to make an impact on an industry that's been doing things a certain way since before they were born.

The five finalists of the Top Founder Under 40 category for the InnovationMap Awards presented by Techwave were asked to share their challenges overcame as young founders. Here's what they had to say. Click here to register for the livestream.

"It wasn't until I stood my ground by being persistent, and by not being afraid to hand their responsibilities to someone else, that they finally took me seriously."

Photo courtesy of CaseCTRL

— Pamela Singh of CaseCTRL says. "While working as on a Department of Defense Contract, I was leading a development effort with other older white men who were mostly retired military," she explains."They did not appreciate a young ethnic female giving them orders, and would often ignore my email requests or assigned tasks. At first, I felt defeated, but then I had to remember that although they have a lot of knowledge in general, I was the one with the right knowledge for this specific project."

"Changing the minds of experienced executives, who have worked in the energy industry for decades, was an uphill battle that took time and a considerable amount of effort."

With fresh funds, this Houston entrepreneur plans to scale his industrial e-commerce startup

Photo by Colt Melrose for GoExpedi

— Tim Neal of GoExpedi. "Over the years, I have enjoyed great success in my professional career, but that has not come without a few challenges," Neal says. "I am incredibly grateful for my mentors who believed in my vision despite my age."

"I think my go getter attitude has always helped me out and aid me mature faster."

Photo courtesy of LAMIK Beauty

— Kim Roxie of LAMIK Beauty. "Since I started at such young age at 21, after being labeled 'at risk' in high school, I think I have always been seen as 'too young,'" she says. "However, My life motto is 'qualify yourself!'"

"Once I started just being myself and not carrying the weight of the no's it really improved my productivity, my leadership, and my overall success as a person and as a leader in my business."

Emily Cisek, CEO and co-founder of The Postage

Photo courtesy of The Postage

— Emily Cisek of The Postage. "I think advocating for myself and my business as a younger female founder has been a challenge mostly because as a person you want to please the people around you, investors, whoever, and sometimes no matter what you do, they aren't going to be on the same page and that's OK," she says. "But not carrying that forward is what's important. There's been times I've been told no, when I was trying to be exactly what I thought an investor or business partner wanted to hear."

"Typically, companies that have been around and have older leadership can have an advantage."

Photo via TMC.edu

— Emma Fauss of Medical Informatics Corp. She says she's experienced age discrimination early on within the health care industry.

Want to work for one of the top startups in Houston? These ones are hiring. Photo by Tima Miroshnichenko from Pexels

Here's which of the InnovationMap Awards finalists are hiring

growing biz

After scouring Houston for the best of the Houston innovation ecosystem and evaluating dozens of companies, InnovationMap has announced the finalists in its inaugural awards. But which of these companies are growing their teams?

Turns out, almost all of them have open positions — some planning to double their teams over the next year. In fact, the 28 companies that make up our cohort of finalists are looking for over 250 new employees — some have these positions open now and others are seeking these new team members over the next 12 months.

Let's look at how many new hires these top startups are looking for.

Biggest gains

The InnovationMap Awards finalist with the loftiest hiring goal is Liongard, which is a finalist in the People's Choice: Startup of the Year category. Liongard — a platform that helps IT companies automatically discover, document, and audit their customers' IT systems — is looking to fill 70 positions over the next year. The company, founded in 2015, has just over 100 employees now.

The startup finalist with the second highest hiring goals is Nanotech, a material science company with a mission to fireproof the world and reduce energy consumption. Nanotech is looking to hire over 40 new employees in the next 12 months, which would almost triple its current staff of 15. Founded in 2019 by Mike Francis, the company is a finalist in both the Energy Transition and People's Choice categories.

Another People's Choice finalist, GoCo, and its all-in-one employee management platform, is currently looking to grow its team by adding 20 new employees to its staff of 53. The company was founded in 2015 and has since raised over $12 million in VC funding.

Also looking to grow their team by 20 new hires is Hello Alice — a small business owner's passport through entrepreneurship that helps with networking, raising capital, and accessing growth tools. The company, co-founded by Carolyn Rodz, is up for an award in the BIPOC-Founded, Female-Founded, and People's Choice categories.

GoExpedi, whose founder and CEO Timothy Neal is a finalist in the Top Founder Under 40 category, currently has 17 positions open at the moment and is looking to add those new hires into its team of over 150 employees. The e-commerce, supply chain, and analytics company is streamlining procurement for industrial and energy MRO (maintenance, repair and operations).

While Female-Founded Business finalist RingOn — a wearable GPS tracker that is also a panic button that's designed for school kids and with an impact-driven mission of ending child trafficking — is only currently looking for six new hires, the company is expecting to hiring another 15 new employees next year. Right now, the company's employee count is at three.

Steady growth

A few of the awards finalists are sporting hiring goals in the seven to 12 new staffers range. Space Tech finalist NANCO Aero, which is developing package- and person-carrying air vehicles, is hiring a dozen new employees — a big goal considering the company currently has just four employees.

Enercross LLC, automation software for the energy industry, is a finalist in the Energy Transition category and is looking to add 11 new people to its team of 42. Meanwhile Sports Tech finalist sEATz — a mobile ordering and delivery platform for food, drinks, and merchandise at large events — is looking to about double its team of 10 over the few months.

Health Tech finalist Medical Informatics Corp. is the creator of Sickbay, which features web-based applications that transform data into actionable information to help care teams make better, faster decisions. The company has seven open positions to grow its team of 36.

Seeking selectively

The following InnovationMap Awards finalists are looking to grow their teams with between two and six new hires:

  • Allotrope Medical — creator of StimSite, a device that improves surgical safety and efficiency in millions of operations performed every year.
  • CaseCTRL — using artificial intelligence and automation to streamline surgical scheduling.
  • Cemvita Factory — engineering microbes that eat CO2 and produce valuable chemicals.
  • Cheers Health — creating products that are designed to support your liver and help you feel better after consuming alcohol.
  • Cognitive Space — providing a scalable satellite constellation management solution to the space industry.
  • Data Gumbo — creator of an interconnected industrial smart contract network secured and powered by blockchain.
  • DonateStock — simplifying the process of donating stock and helping nonprofits solicit, process, and manage stock donations.
  • FitLift — a wearable device and mobile platform that tracks motion and gives real-time feedback on lifting technique, allowing trainers, and athletes to drive results.
  • LAMIK Beauty — a tech-enabled clean color cosmetics company focusing on women of all diverse backgrounds
  • Molecule Software — creator of a leading cloud-native energy trading software.
  • re:3D Inc. — producer of large, affordable industrial 3D printers, and services that can print with new or recycled filament, pellets, or flake.
  • Saranas — creator of the Early Bird, the first and only FDA-approved bleed detection system for endovascular procedures.
  • Starling Medical — using AI and telehealth enabled medical devices to enable millions with bladder dysfunctions to be able to urinate safely and conveniently again.
  • Topl — impact monetization engine that enables digital and sustainable transformation across value chains and empowers the monetization of impact verified on the Topl Blockchain.
  • Zibrio Inc. — a fall prevention solution that empowers both clinicians and patients for better outcomes.

Find out which of these employers take home the win at the September 8 event at The Cannon - West Houston. Honorees, sponsors, judges, and their guests will celebrate in person, and the rest of the innovation community is invited to tune in to the livestream. Click here to RSVP.

Sponsorships are still available! If you are interested in partnering with InnovationMap as a sponsor of this event, send an email to awards@innovationmap.com.

And the finalists for the inaugural InnovationMap Awards are... Graphic via Gow Media

InnovationMap names 28 Houston startup finalists for inaugural awards

who will take home the win?

Who are Houston's rising stars across energy transition, sports tech, health, and more? InnovationMap set out on a quest to discover that for its inaugural awards. Ahead of the September 8 event, we're revealing the finalists across all categories.

Eight judges evaluated over 100 applications across eight categories for the 2021 InnovationMap Awards presented by Techwave. This year's judges included: Juliana Garaizar, head of the Houston incubator and vice president of innovation at Greentown Labs; Alex Gras, managing director at The Cannon; Rajasekhar Gummadapu, co-founder and CEO of Techwave; Natalie Harms, editor of InnovationMap; Serafina Lalany, interim president at Houston Exponential; Jon Nordby, managing director at MassChallenge; Emily Reiser, senior manager of innovation community engagement at the Texas Medical Center; and Grace Rodriguez, CEO and executive director of Impact Hub Houston.

The winners will be announced and celebrated — along with this year's previously announced Trailblazer Award recipient, Barbara Burger of Chevron Technology Ventures — at the September 8 event at The Cannon - West Houston. Honorees, sponsors, judges, and their guests will celebrate in person, and the rest of the innovation community is invited to tune in to the livestream. Click here to RSVP.

Sponsorships are still available! If you are interested in partnering with InnovationMap as a sponsor of this event, send an email to awards@innovationmap.com.

Without further adieu, here are this year's finalists:

BIPOC-Founded Business Finalists

The finalists for the BIPOC-Founded Business Award category, honoring innovative tech companies founded or co-founded by BIPOC representation, are:

  • Allotrope Medical — creator of StimSite, a device that improves surgical safety and efficiency in millions of operations performed every year.
  • Hello Alice — a small business owner's passport through entrepreneurship that helps with networking, raising capital, and accessing growth tools.
  • LAMIK Beauty — a tech-enabled clean color cosmetics company focusing on women of all diverse backgrounds
  • Molecule Software — creator of a leading cloud-native energy trading software.

Female-Founded Business Finalists

The finalists for the Female-Founded Business Award category presented by Veritex Community Bank, honoring innovative tech companies founded or co-founded by women, include:

  • DonateStock — simplifying the process of donating stock and helping nonprofits solicit, process, and manage stock donations.
  • Hello Alice — a small business owner's passport through entrepreneurship that helps with networking, raising capital, and accessing growth tools.
  • re:3D Inc. — producer of large, affordable industrial 3D printers, and services that can print with new or recycled filament, pellets, or flake.
  • RingOn — wearable GPS tracker that is also a panic button that's designed for school kids and with an impact-driven mission of ending child trafficking.
  • Topl — impact monetization engine that enables digital and sustainable transformation across value chains and empowers the monetization of impact verified on the Topl Blockchain.
  • Zibrio Inc. — a fall prevention solution that empowers both clinicians and patients for better outcomes.

Health Care Business Finalists

The finalists for the Health Care Business Award category presented by Gray Reed, which honors health care businesses with an innovative solution within life sciences, include:

  • Allotrope Medical — creator of StimSite, a device that improves surgical safety and efficiency in millions of operations performed every year.
  • Medical Informatics Corp. — creator of Sickbay, which features web-based applications that transform data into actionable information to help care teams make better, faster decisions.
  • Saranas — creator of the Early Bird, the first and only FDA-approved bleed detection system for endovascular procedures.
  • Starling Medical — using AI and telehealth enabled medical devices to enable millions with bladder dysfunctions to be able to urinate safely and conveniently again.

Energy Transition Business Finalists

The finalists for the Energy Transition Business category, which honors energy business with innovative solutions within renewables, climatetech, clean energy, and beyond, are:

  • Cemvita Factory — engineering microbes that eat CO2 and produce valuable chemicals.
  • Data Gumbo — creator of an interconnected industrial smart contract network secured and powered by blockchain.
  • Enercross LLC — automation software for the energy industry.
  • Nanotech — a material science company with a mission to fireproof the world and reduce energy consumption.
  • re:3D Inc. — producer of large, affordable industrial 3D printers, and services that can print with new or recycled filament, pellets, or flake.
  • Renewell Energy — converting idle oil and gas wells into flexible energy storage.

Sports Tech Business Finalists

The finalists for the Sports Tech Business category, which is honoring a sports tech business with an innovative solution within sports are:

  • FitLift — a wearable device and mobile platform that tracks motion and gives real-time feedback on lifting technique, allowing trainers, and athletes to drive results.
  • Mainline — an esports tournament management system, tournament organizer, and event production company.
  • sEATz — a mobile ordering and delivery platform for food, drinks, and merchandise at large events.

Space Tech Business Finalists

The finalists for the Space Tech Business category, which is honoring an aerospace business with an innovative solution within space exploration. are:

  • Cemvita Factory — engineering microbes that eat CO2 and produce valuable chemicals.
  • Cognitive Space — providing a scalable satellite constellation management solution to the space industry.
  • NANCO Aero — developing package- and person-carrying air vehicles.

Top Founder Under 40 Finalists

The finalists for the Top Founder Under 40 category, which honors an innovative founder younger than 40 by Sept. 8, 2021, are:

  • Pamela Singh of CaseCTRL — using artificial intelligence and automation to streamline surgical scheduling.
  • Timothy Neal of GoExpedi — an e-commerce, supply chain, and analytics company that is streamlining procurement for industrial and energy MRO (maintenance, repair and operations).
  • Kim Roxie of LAMIK Beauty — a tech-enabled clean color cosmetics company focusing on women of all diverse backgrounds.
  • Emma Fauss of Medical Informatics Corp. — creator of Sickbay, which features web-based applications that transform data into actionable information to help care teams make better, faster decisions.
  • Emily Cisek of The Postage — a legacy planning platform using tech to make afterlife decision making easier.

People’s Choice: Startup of the Year Finalists

The finalists for the People's Choice: Startup of the Year category, which will each present a 60-second live elevator pitch at the event on September 8, are:

    • Cheers Health — creating products that are designed to support your liver and help you feel better after consuming alcohol.
    • GoCo — all-in-one employee management platform.
    • Hello Alice — a small business owner's passport through entrepreneurship that helps with networking, raising capital, and accessing growth tools.
    • Liongard — a platform that helps Information Technology companies automatically discover, document, and audit their customers' IT systems.
    • Nanotech — a material science company with a mission to fireproof the world and reduce energy consumption.
    • re:3D Inc. — producer of large, affordable industrial 3D printers, and services that can print with new or recycled filament, pellets, or flake.
    • Topl — impact monetization engine that enables digital and sustainable transformation across value chains and empowers the monetization of impact verified on the Topl Blockchain.

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    Autonomous truck company with Houston routes goes public

    on a roll

    Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

    Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

    In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

    “We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

    “We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

    Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

    The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

    One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

    Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.

    Rice University scientists invent new algorithm to fight Alzheimer's

    A Seismic Breakthrough

    A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

    Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

    For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

    To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

    “As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

    Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

    “We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

    Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

    “We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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    This article originally appeared on CultureMap.com.

    5 incubators and accelerators fueling the growth of Houston startups

    meet the finalists

    Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

    As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

    Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

    Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

    Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

    Activate

    Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

    This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

    EnergyTech Nexus

    Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

    The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

    Greentown Labs

    Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

    Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

    Healthtech Accelerator (TMCi)

    The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

    The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

    Impact Hub Houston

    Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

    There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

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    The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.