Houston startup expands nationally, teams win DOE prize, and more local innovation news

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From a new hard tech grant opportunity to apply for to health tech innovation expansion, here's your latest roundup of Houston startup and innovation news you may have missed. Photo via Getty Images

As Houston ramps up for fall, the city's innovation news has followed suit, and there might be some headlines you may have missed.

In this roundup of short stories within Houston startups and tech, Houston angel investors dole out prize money, the DOE grants Houston innovators some cash, a digital health company expands, and more.

2 Houston teams win DOE geothermal manufacturing prize

Both of the teams that won this competition hailed from Houston. Image via energy.gov

This week, the U.S. Department of Energy announced that two Houston-based companies have won the American-Made Geothermal Manufacturing Prize — a $4.65 million competition to incentivize innovators to use 3D printing, or additive manufacturing, to address the challenges associated with operating sensitive equipment in harsh geothermal environments, per a press release. The competition challenged participants with quickly developing, testing, and revising prototypes using additive manufacturing to support the advancement of geothermal tools and technologies.

“This DOE competition harnesses breakthroughs in additive manufacturing to help overcome barriers to widespread deployment of geothermal energy,” says Alejandro Moreno, deputy assistant secretary for renewable power, in the release. “The rapid prototype development supported by this prize is spurring advancements in the geothermal industry to help power the nation from the heat beneath our feet.”

The competition launched in January 2020, and the finalists presented their innovations at the annual Geothermal Rising conference in Reno, Nevada. The winning teams each were awarded $500,000 in cash and up to $200,000 to test their innovations in the field. The two Houston-based winning teams were:

  • Team Downhole Emerging Technologies: "This team developed an alternative to traditional packer systems," the release states. "The all-metal, retrievable packer system is designed specifically for high temperatures, extreme pressures, and corrosion experienced in geothermal wells. The Downhole Emerging Technologies’ partnership resulted in the production of the largest Inconel additively manufactured component by Proto Labs, Inc. and the development of DET’s tool, the Diamond ETIP (Extreme Temperature Isolation Packer).”
  • Team Ultra-High Temperature Logging Tool: "This team developed a technology that uses a labyrinthian heat sink to reduce thermal emissivity and increase the exposure time of temperature sensitive electronic components," according to the release. "Oak Ridge National Laboratory used a powder bed laser fusion technique to manufacture the heat sink design, with the aim that the technology would solve limitations around maximum temperature rating and lifetime of electronics in logging and measurement tools. The team also worked closely with Sandia National Laboratories to test the logging prototype in a high-temperature setting."

Koda Health expands across the country

Koda Health has gone nationwide. Image via kodahealthcare.com

Houston-based Koda Health has announced via LinkedIn that it has expanded into a handful of new states recently: Florida, Oregon, North Carolina, Virginia, California, and Maryland. These six expansions have all been announced over the past month following the announcement in July that the company is going nationwide.

"Every state has different regulations and requirements for their advancecare planning documents. So, the folks at Nixon Gwilt Law and Koda Health have been hard at work making our platform compliant in every single state," the company announced in a post. "It's hard work, but we're committed to helping patients stay in control of their health care journey, regardless of where they call home."

Koda Health was born out of the TMC's Biodesign Fellowship and launched by Tatiana Fofanova, Dr. Desh Mohan, and Katelin Cherry in March of 2020. The platform uses AI to help patients create advanced medical care directives and documents, such as a living will, through its proprietary machine learning approach.

In February, Koda closed over $3 million in seed funding in order to grow its staff and support expansion. Now, including Texas, Koda is in seven states across the country.

Houston angels dole out cash to RBPC winner

Hoth Intelligence — a digital health startup — is cashing in on its RBPC prizes. Photo via Getty Images

The Houston Angel Network announced its investment of over $160,000 in Hoth Intelligence, the winner of HAN’s prize at the 2022 Rice Business Plan Competition.

“Following the HAN award announcement at the RBPC banquet, we learned that the Houston Chapter of The Indus investor Entrepreneurs (TiE) was also interested in Hoth as an investment for its members," says HAN Chairman Richard Hunter in a news release.

The organizations collaborated on due diligence and negotiation of the investment terms. Hunter led HAN's due diligence and Jeff Tomlinson led the effort on behalf of TiE.

The company, which was established at University of Pittsburgh, has developed an artificial intelligence platform for health care providers. The company's RBPC prize initially totaled $386,700 in investment awards from a handful of entities.

Per HAN's news release, Houston investment firms Prosalus Capital Partners joined in with a $300,000 investment and PiFei VC contributed an additional $100,000.”

“Several companies at the 2022 RPBC, including Hoth Intelligence, ranked very high in the TiE judging," says TiE Houston Chapter President Ram Shenoy. "We therefore decided to pursue due diligence and were very pleased to have worked with HAN to expeditiously complete the deal. To date, it has attracted TiE investors from chapters in Atlanta, Silicon Valley, and Southern California who have committed over $154,000 in investment.”

Sustainable biz tapped for prestigious program

This Houston entrepreneur is getting ready to pitch. Image courtesy

Houston-based Trendy Seconds was chosen as part of the SOCAP Global Entrepreneur 2022 Cohort — a prestigious event in the social entrepreneurship world that grants scholarships to entrepreneurs from all over the globe.

Trendy Seconds is an online marketplace where women can find pre-owned clothing or shop for new clothing from sustainable brands. The company shares items from more than 50 brands that can be searched by category, style, size, price, condition, and positive impact. To ensure the clothing is high quality, shoppers will find only gently-used or new items featured on Trendy Seconds.

Through the program, Founder Maria Burgos will pitch live in San Francisco on October 20.

Deadline approaches for Activate Anywhere

Calling all scientists on a mission. Image via Getty Images

A global accelerator billed as "for scientists on a mission" has opened its latest round of registration. Activate Anywhere is a remote-based program for hard tech innovators that takes no equity, requires no fees, and provides significant financial support, including a living stipend of up to $110,000 a year, $100,000 in R&D funding, $100,000 additional flexible capital, health care coverage, travel allowance, and more.

Applications September 15, but registration to apply is free and open now. The deadline to apply is October 31 and finalists will be announced in February.

To be eligible for the program, you must:

  • have a bachelor’s degree and at least four years post-baccalaureate scientific research, engineering, or technology development experience.
  • be the leader of a technical project or company that is relevant to our target industries and is based in the physical or biological sciences, or related engineering disciplines.
  • be leading the commercial development of a hardware-based technology innovation for the first time i.e. not a repeat hard-tech founder. You may apply as a solo applicant or with one co-applicant.
  • not have raised more than $2 million in debt or equity funding from non-governmental sources for the proposed project at the time of the application deadline.
  • be able to work in the U.S. for the duration of the fellowship, and have access to a qualified host laboratory.

This week's roundup of Houston innovators includes John "JR" Reale of the TMC, Maria Burgos of Trendy Seconds, and Christopher Howard of Softeq. Courtesy photos

3 Houston innovators to know this week

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Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from venture funding to startup acceleration — recently making headlines in Houston innovation.


John "JR" Reale, executive in residence at Texas Medical Center Innovation and managing director of Integr8d Capital

John "JR" Reale joined the Houston Innovators Podcast for a special two-part series. Photo courtesy of TMC

John "JR" Reale has seen the evolution of Houston's innovation ecosystem from day one. Recently, he joined InnovationMap for a two-part series on the Houston Innovators Podcast to discuss the city's evolution as a tech and startup hub as well as what he's up to nowadays — leading venture activity at the Texas Medical Center Innovation and within his own firm.

"One of the most important moments for Houston was when we got kicked in the teeth with the Amazon HQ2 bid," he says on the show. "Amazon came back with the shortlist of the 20 cities in North America — and Houston isn't on it. I remember being excited. It was arguably the most innovative company in the world saying 'no thank you.'"

Flash forward, and Houston's a different ecosystem — still with a ways to go. Click here to stream part one and part two of the series.

Maria Burgos, founder of Trendy Seconds

A Houston innovator found second-hand shopping time consuming. So, she designed a better experience. Image courtesy of Trendy Seconds

After donating her items to a local church, Maria Burgos sought to be more sustainable and decided to try secondhand shopping.

“The good news was that I had so many options, new with tags, great conditions…the bad news was that it was so much that I ended up being frustrated because I didn't find what I liked,” she tells InnovationMap. “I had to spend hours of my time scrolling thousands of items, dozens of filters, multiple platforms."

She asked herself why there wasn’t a website where she could find items in one place. “That was the genesis of Trendy Seconds,” she shares. Click here to read more.

Christopher Howard, founder and CEO of Softeq

Chris Howard, CEO and founder of SofteqA Houston software company has announced its new venture fund. Photo courtesy of Softeq

Houston-based Softeq Development Corp. announced its third group of early-stage startups to join the Softeq Venture Studio, which is geared at helping its resident startups quickly develop their technology and build their businesses. With 14 startups, the summer 2022 cohort is the largest yet and brings the total portfolio to 27 companies. Additionally, the $40 million Softeq Venture Fund welcomed Royal Eagle Capital Partners, a Houston-based investment firm, as a limited partner with its $3 million commitment.

“We are thrilled to see how much the Softeq Venture Studio has grown since 2021,” says Christopher A. Howard, founder and CEO of Softeq, in a news release. “We’re also pleased to welcome Royal Eagle Capital Partners as an investment partner in our Venture Fund, which allowed us to achieve more than 50 percent of our funding goal in just five months. We look forward to building on this partnership and growing Softeq in North America, Latin America, and beyond.”

Softeq is also celebrating a recent expansion into Latin America and staffing the new regional office with 30 engineers. The company has plans to grow to 150 employees in the region over the next year. Click here to read more.

A Houston innovator found second-hand shopping time consuming. So, she designed a better experience. Image courtesy of Trendy Seconds

Houston startup seeks to simplify sustainable fashion

design innovation

When the coronavirus pandemic started in 2020, people found themselves at home with a surplus of free time. Puzzles covered dining room tables, remnants of new hobbies were strewn across dens, TikTok dances were rehearsed, and television was binged. Maria Burgos found herself watching Netflix’s “Tidying Up with Marie Kondo,” which inspired her to clean out her closet. In practicing Kondo’s dogma of parting with items that don’t “spark joy,” Burgos uncovered a bigger issue to purge: America’s unsustainable fashion industry.

With piles of clothing ready for a new home, Burgos searched for reliable organizations to donate her possessions. Her research led her to learn more about the negative impact the fashion industry has on the environment.

According to Slate, almost 24 billion pounds of clothes and shoes are thrown out each year — more than double what we tossed two decades ago. Americans consume more than 20 billion garments each year, and each garment can be expected to be worn around seven times, according to The Wall Street Journal. We’re buying more clothing than ever when clothing is at its lowest cost.

A $17.99 linen crop top from H&M may seem like a steal, but the low price tag poses a much greater cost for the environment. Low-quality garments have a bleak chance of finding a secondhand home, and 80 percent of donated clothing won’t ever be seen see a charity shop rack. While some used clothing gets recycled as insulation, others end up in containers that overwhelm charities abroad or sit in landfills.

After donating her items to a local church, Burgos sought to be more sustainable and decided to try secondhand shopping.

“The good news was that I had so many options, new with tags, great conditions…the bad news was that it was so much that I ended up being frustrated because I didn't find what I liked,” she says. “I had to spend hours of my time scrolling thousands of items, dozens of filters, multiple platforms."

She asked herself why there wasn’t a website where she could find items in one place. “That was the genesis of Trendy Seconds,” she shares.

Maria Burgos founded Trendy Seconds to streamline second-hand shopping. Photo courtesy

Burgos has always been drawn to entrepreneurial aspirations. The Venezuela native started her first company, a film magazine, while in college. She studied dentistry and graduated with an offer to become a professor at her university, which she turned down to explore her passion for marketing further. After moving to Spain to obtain an MBA, she gained experience working for large corporations like 3M and GlaxoSmithKline.

Living in countries around the world and dipping her toes into different industries, Burgos gained a unique resume. When she came to the United States, she was eager to get her work permit. She obtained a real estate license and even began working at a startup before having her second child.

“I don't ever have the profile that is right to do what I'm doing at the moment, professionally. That has been something that I considered years ago as a disadvantage, [but] that has been my advantage because I come with a fresh pair of eyes,” she explains. “I solve problems differently, and I throw ideas out there that maybe other people don't,” she continues.

When she thought of Trendy Seconds, Burgos was trying to solve the issues she faced while striving to be a conscious consumer.

“I know that there are many other women like myself that are trying to make better choices, but right now, it's too hard,” she says.

She applied and graduated from the Founders Institute and won a Frost Bank grant to join Impact Hub Houston’s accelerator program.

“The accelerator opened up a lot of doors for me, and I went through all of them,” she shares.

Burgos launched Trendy Seconds, as an online marketplace where women can find pre-owned clothing or shop for new clothing from sustainable brands. The company shares items from more than 50 brands that can be searched by category, style, size, price, condition, and positive impact. To ensure the clothing is high quality, shoppers will find only gently-used or new items featured on Trendy Seconds.

Shoppers can have a much more cultivated experience on Trendy Seconds. Image courtesy

“We work with a fashion stylist to curate the product assortment because one thing that happens is analysis paralysis. When you have too many choices, you don't take action,” says Burgos.

Trendy Seconds creates wardrobe capsules that include an assortment of versatile styles that can be mixed and matched together. Visitors can search for various styles like beachwear, spring/summer, maternity, and special occasion attire.

Burgos has aligned with online secondhand marketplaces as well as sustainable clothing websites, where shoppers are redirected once they find items to purchase. She uses the United Nations’ sustainability goals to vet vendors and determine which brands to include on the website. Some featured eco-conscious brands include Christy Dawn, Eileen Fisher, Soul Flower, and Allbirds.

“Our ultimate goal is to make responsible consumption super easy,” Burgos explains.

Trendy Seconds is currently fundraising and Burgos is looking to bring in investors as she expands the company.

In the future, Burgos wants Trendy Seconds to evolve past the online marketplace and become a resource for circular fashion.

“How we envision this is that we will give the opportunity to consumers to come to the site and not just buy clothes, but actually purchase products and services that can help them increase the life of the clothes that they already have,” she shares.

“I believe that the best way to create a really good, like, motivated consumer audience is by letting them know how can they how can they help,” says Burgos.

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Houston ranks high on best cities for small-business expansion report

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For small businesses looking to expand, Houston might be the right place.

Among 56 major U.S. metros, Houston grabbed the No. 6 spot on a new list of the metros boasting the strongest environments for small-business expansion.

A 2025 report from the state comptroller’s office showed roughly 970,000 small businesses operate in the 13-county Gulf Coast region. The region includes the majority of the Houston metro area.

“Whether it’s a family-owned shop on Main Street or a fast-growing startup, small businesses power our state’s economic engine, create opportunity, and strengthen the character of every Texas community,” Kelly Hancock, who was interim state comptroller when the report was released, said in a press release.

Business lending platform Clarify Capital analyzed five factors to develop the list: job growth, business entry and exit, net job creation, and unemployment.

Overall, the Nashville area claimed the No. 1 spot on the list. Other major Texas metros also cracked the top 10, including Austin at No. 3 and Dallas-Fort Worth at No. 7.

“The highest-ranking metros combine labor-market momentum with steady business formation and relatively favorable local employment conditions,” Clarity Capital says.

The Houston metro ranked sixth for job growth, 11th for business entry rate, 38th for business exit rate, second for net job creation rate, and 50th for unemployment rate.

“For business owners, the ranking is a starting point rather than a guarantee,” Clarify Capital says. “Local demand, competition, operating costs, and access to capital still shape whether an expansion works.”

“Building enough cash-flow room for hiring, equipment, and unexpected expenses can help small and midsize business owners take advantage of a strong market without stretching the business too thin,” the company adds.

Of course, money fuels small-business expansion in the Houston area or anywhere else.

According to an analysis of SBA loan data by feasibility consulting firm MMCG, the Houston metro area saw 1,685 approvals for 7(a) loans and 101 approvals of 504 loans in the federal government’s 2025 budget year. The approval numbers for both loan categories increased from the previous year.

Altogether, the 7(a) and 505 loans exceeded $1 billion.

The data from the U.S. Small Business Administration suggests small-business expansion may be on the rise in the Houston area.

Further potential evidence of small-business expansion in the Houston area: The region experienced a 92 percent rise in account applications from 2024 to 2025 submitted to Bluevine, a small-business banking platform. The Houston metro ranked fifth for the number of Bluevine small-business applications in 2025.

What to expect from the inaugural TiECon Texas event this week

where to be

Innovators and entrepreneurs will gather in Houston this week to show off their latest advancements in automation during the first-ever TiECon Texas conference at the Ion District.

“Automation is not simply changing how we work. It is redefining how value is created across every industry,” Somesh Singh, president of TiE Houston, said in a release. “Texas has the talent, the infrastructure, and the entrepreneurial spirit to lead this transformation. TiEcon Texas 2026 is where the people building that future will come together to shape it."

The Indus Entrepreneurs (TiE) started in Silicon Valley in 1994 as a two-day seminar, but has grown into a worldwide network of events celebrating technological advancement. TiECon in Houston is a merger of the TiE networks across Texas for one large-scale event taking place at the Ion on Wednesday, October 28, and Thursday, October 29. Tickets are available here.

The event includes a partnership with Hatch Pitch, a founder-first startup showcase that has raised over $20 billion in funding for new companies in the tech industry. Participants will come from industries like space exploration, healthcare, energy, and the AI sector to present their ideas in front of an investor network for possible development.

“Over 80 percent of the teams we have coached have gone on to receive funding,” Greg Wright, founder of Hatch Pitch, added in a release.

In addition, there will be forums and talks on a variety of automation subjects, everything from robotic surgery to automation in government. Educators from Baylor College of Medicine, UTHealth Houston, and the University of Houston plan to discuss the raising of children in a world with extensive artificial intelligence integrated into so many areas. Steven Kean, President and CEO of the Greater Houston Partnership, will give the keynote speech on the Bayou City’s place in these emerging technological spheres.

Singh highlighted how the large-scale disruptions in the technological status quo by the rise of AI could be a sign of potential growth and innovation. The entrepreneurs presenting at TiECon may be the ones to harness the sometimes unsteady AI industry for good causes.

“History shows that periods of technological disruption create extraordinary opportunities for those prepared to act,” he said. “TiEcon Texas is designed to help founders, investors, and enterprises understand where the automation economy is headed and how to participate in building it."

Here are the 10 startups pitching during the TiE Hatch Pitch competition:

Houston startup makes Time's list of the best inventions of 2026

Innovation Station

One of the year's most buzzworthy innovations comes from a Houston-based leader in the energy transition. Utility Global's H2Gen recently made Time magazine’s list of the 300 best inventions of 2026.

The H2Gen is an innovative system that produces low-cost clean hydrogen from water and industrial off-gases. The company says the process doesn’t require electricity, a notable claim since hydrogen production typically consumes a lot of power.

"Using a tubular electrochemical cell containing a proprietary electrolyte and water, the company can turn industrial off-gases into hydrogen at scale—no extra electricity required," writes Time. "Bonus: the process also pulls out carbon dioxide as a separate stream, where it can be captured and kept out of the atmosphere.

CEO Parker Meeks tells Time, it's “a practical pathway to decarbonize existing industrial assets."

The startup is on a roll. It has raised $100 million so far in an ongoing Series D round to offer its decarbonization technology at industrial scale around the world.

H2Gen is joined by 10 other inventions with Texas connections onTime's list, as well as one "special mention."

In North Texas, they are:

Samsung
Plano-based Samsung Electronics America pulled off a hat trick this year, with three products making Time’s list. First up is the Galaxy S26 Ultra smartphone. It packs a more powerful camera, Galaxy AI features, and pro-level content creation tools. But Time singled out its new built-in privacy display as the phone’s “biggest selling point.”

Samsung’s Bespoke AI Family Hub refrigerator also got smarter. When AI first came to the Family Hub in 2024, it could recognize some fresh foods, but you still had to log packaged items by hand, Time noted. Now, with Google Gemini built in, the fridge can identify more than 2,000 packaged foods, read handwritten labels, and warn you when food is about to expire. It then uses what’s inside to build grocery lists and suggest recipes.

And for gamers, there’s the Odyssey G8 monitor. Its 6K resolution leapfrogs the 4K standard, delivering what Samsung calls “exceptional visual clarity and detail” on a screen big enough for gaming and multitasking.

OxeFit
Plano-based OxeFit’s XS1 Peak is about the size of a treadmill but works like an entire gym. It can be set up for strength training, simulated skiing or kayaking, Pilates, or rowing. What makes it stand out is a built-in virtual spotter. According to Time, the machine “uses AI, computer vision and sensors to correct the user’s form, change resistance in the middle of a rep and reduce the weight when the user is struggling, much like a human spotter.”

EssilorLuxottica
EssilorLuxottica, the French eyewear giant whose U.S. headquarters is in Farmers Branch, makes Essilor Stellest lenses. The lenses correct nearsightedness while also slowing the eye growth that makes it worse over time. Stellest is the first and only eyeglass lens authorized by the U.S. Food and Drug Administration to control myopia, Time said. The lenses look like regular glasses but contain 1,021 tiny lenslets. In a U.S. trial of kids ages 6-12, myopia progression slowed by an average of 71 percent over two years compared with standard lenses.

Helpany
Helpany, a startup based in Phoenix that manufactures its devices in DFW, makes Paul, a ceiling-mounted gadget that uses radar and AI to spot subtle changes in how residents move and flag those at higher risk of falling. Helpany says the technology can cut falls by as much as 72 percent.

Aurora Innovation
Aurora, based in Pittsburgh with a corporate and operations hub in Coppell, rolled out its second-generation Driver 2 system in July. By September, Driver 2 trucks had logged more than 500,000 driverless miles without a single at-fault crash, Time reported, and the company expects 200 of them on the road by the end of 2026.

Colossal Biosciences
Dallas-based Colossal Biosciences built an artificial egg by placing an ultra-thin, transparent silicone membrane inside a rigid 3D-printed cup, letting scientists watch the embryo develop. Twenty-six chickens have already been hatched.

In Austin, they are:
Cedar Park-based Hyliion landed on Time’s list with its Karno Power Module, a modular generator designed to produce power wherever it’s needed. The Karno represents a big pivot for the company. Hyliion got its start building electrified powertrains for 18-wheelers before shifting into power generation after acquiring the Karno generator technology from GE Aerospace. Founded in Pittsburgh in 2015, the company relocated to Cedar Park in 2018.

The other Austin-associated honoree is Moment Energy. As more electric vehicles hit the road, a growing number of their batteries are nearing retirement, while demand for power keeps climbing. Moment Energy found a way to tackle both problems at once. The company’s Megafactory 1, which opened in Vancouver, Canada, in June, turns old EV batteries into modular energy storage systems for hospitals, factories, data centers, and other big power users. “Our goal is to make sure these batteries don’t end up in landfills,” founder Edward Chiang told Time.

In the “Special Mentions” category, Austin-based Renzoe Box gained notice for its refillable custom makeup palette for on-the-go people. Licensed architect René Graham designed the box. She graduated from Houston's Rice University, and was born and raised in Dallas.

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A version of this article first appeared on CultureMap.com.

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