Overheard: NASA administrator shares Houston's potential as a commercial space hub

eavesdropping online

NASA Administrator Jim Bridenstine joined the Greater Houston Partnership for the State of Space online event this week. Photo via NASA.gov

The Greater Houston Partnership hosted its inaugural State of Space event featuring a keynote address by Jim Bridenstine, NASA administrator, that touched on the many ongoing projects at Houston's Johnson Space Center.

The online event, which also featured speeches from GHP President Bob Harvey and JSC Mark Geyer, took place Tuesday, December 15, for GHP members and nonmembers alike.

In his address, Bridenstine discussed the commercialization of space, how politics have affected the agency's history, and the exciting projects underway — including returning man to the moon. Missed the discussion? Here are some significant overheard moments from the virtual event.

"Houston is a city that chooses to take on humankind's boldest challenges head-on, and through that work we have built Houston as a technology-oriented city."

— Bob Harvey, president and CEO of the Greater Houston Partnership. Harvey called out, specifically, the Johnson Space Center and its history as the mecca for human space flight, as well as the emerging Houston Spaceport, which hopes to combine innovation across industries, from space to energy and life sciences.

"In fiscal year '21, NASA will see the first two lunar landings of the agency's Commercial Lunar Payload Services — this is an initiative led in Houston where American companies will serve science and technology payloads to the surface of the moon to prepare for human missions."

— Mark Geyer, director of JSC. Geyer mentions this initiative specifically, as well as 2020's collaboration with SpaceX to have the first American launch since 2011. Geyer also calls out NASA's new Commercial Crew Program. "All of these things position Houston to be a leader and a focal point for this new commercial space ecosystem, which is national and global in nature," Geyer says.

"We are very fortunate to have a center like Johnson in a city like Houston — a city that produces talent, that has an amazing workforce, a dedication to education and to the STEM fields."

— Jim Bridenstine, NASA administrator. Bridenstine, a Rice University alumnus, adds that the JSC currently has more programs and projects under development at any point in history.

"Johnson is focused like a laser on Mission Control. ... The No. 1 project NASA has, which we celebrated last month, is 20 years of humans working and living in space continuously."

— Bridenstine says, noting some of the continued missions like Artemis, which will return humans to the surface of the moon, and Gateway, an outpost orbiting the moon to support continued human space exploration.

"Our goal is to put an American flag on Mars — the moon is the proving ground, and Mars is the destination."

— Bridenstine says regarding NASA's focus on returning to the moon.

"I am judging my time as NASA administrator based on whether or not — when my children are my age — we are still on the moon and on Mars."

— Bridenstine says. He notes that part of moving forward is looking back and learning about programs got canceled and why, and which ones were sustainable and why. In some cases, says Bridenstine, who served in U.S. Congress for five years, it was due to divisive politics.

"The Johnson Space Center is quite well positioned for attracting a lot of commercial industry and international partners."

— Bridenstine says when asked about Houston's potential for attracting space business. He mentions how crucial Houston-based Mission Control is and always has been, as well as the emerging focus on Gateway, which will be open for other countries to be supported by. "I think Houston is in great shape — between Mission Control and the Gateway."

NASA technology is up for grabs and InnovationMap has a new podcast — here are some innovators to know this week. Courtesy photos

3 Houston innovators to know this week

who's who

Another Monday means another weekly roundup of who's who in Houston innovation.

This week, we have our first Houston Innovators Podcast guest to feature, as well as a NASA expert who wants to loan you space technology.

Jon Nordby, managing director at MassChallenge Texas

Courtesy of MassChallenge

On our first episode of the new Houston Innovators Podcast, we discuss Houston accelerators with Jon Nordby, managing director for MassChallenge Texas. The first Houston program launched this year, and, as the organization looks toward its next cohort, the Houston innovation ecosystem is evolving in front of our eyes.

To read more about Nordby and MassChallenge, click here to read the story and listen to the podcast.

Sara Kelly, founder of Rigby

Courtesy of Rigby

Sara Kelly thinks you shouldn't have to get married or buy a house to have a nice dish set. She created Rigby, a Houston-based direct-to-consumer tableware company that is flipping the script on dishes.

"The reaction to the brand and the product has been great," says Kelly. "It's been so exciting for me to see that. At this point, we're focused on organic growth since we're so new."

Click here to read more about Rigby.

Steven Gonzalez, technology transfer strategist at NASA

Courtesy of NASA

Steven Gonzalez's job is to move NASA technology out into the world. The Johnson Space Center has hundreds of technology applications and IPs, and so much more can be done with those ideas here on earth. In a guest column for InnovationMap, Gonzalez writes of the NASA Johnson Space Center Technology Transfer and Commercialization Office, which will loan technology licenses to startups for free for three years.

"New technologies have been researched, developed, and proven on the ground — as well as above the earth on the International Space Station — in fields including medical, communications, agriculture, manufacturing, materials, structures, and much more," he writes. "At NASA's JSC, we are proud of the exceptional innovators who continue to develop technologies that advance the space program and technology for society on our home planet, and we love to share our knowledge."

Click here to read more about the program.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

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