Houston investment group names new leadership

movers & shakers

Goose Capital recently named its new managing director, president, and board chair. Photo courtesy

A Houston-based investment group has announced three new leadership changes to its organization to start of the new year.

Goose Capital Inc. named Chris Staffel as managing director, along with Jeff Smisek as the firm's president and Jay Collins as chair of the board of directors. The three appointments are effective as of January 1.

Smisek, former chairman, CEO, and president of United Continental Holdings Inc., has been a member investor with Goose but now assumes this leadership role. He serves as president of private investment company Flight Partners Capital, as well as on the board of directors for Finch Therapeutics Group Inc., Lantha Inc., and Molecular Match Inc.

"I look forward to leading Goose Capital as we help early stage companies and their founders develop their products, grow their companies, and create value," says Smisek in a news release.

Collins formerly lead Oceaneering International as CEO and president. He currently serves on the board of directors of the company as well as on the boards of Murphy Oil Company and Pason Systems Inc. Prior to becoming chair of the board of Goose Capital, Collins was its president.

A serial entrepreneur and investor in over 30 startups, Staffel joins Goose to lead day-to-day operations and drive new investment opportunities. She has been a founding member of three startup energy companies with an aggregate exit valuation of $1.38 billion, according to the release, as well as formerly leading Houston-based digital health company, Patients We Share, as COO. Her appointment to the firm follows former director Samantha Lewis's move to Mercury Fund.

"It is an honor to join the team at Goose Capital and work alongside experienced industry leaders," Staffel says in the release. "I look forward to leveraging my entrepreneurial experience to help the start-ups in which we invest, while strategically identifying early stage investment opportunities."

Goose Capital — previously known as The GOOSE Society of Texas — was founded 15 years ago and invests about $10 million per year in early-stage companies. Last summer, the organization rebranded with a new website representing a new phase for the investment group.

GOOSE Society of Texas has invested in a chemical sensor company from Austin. Pexels

Houston investor group leads $2.6 million Series A round for Austin-based chemical sensor startup

Money moves

A Houston-based investment group has announced funding for a startup out of Austin that has the potential to disrupt multiple industries with its chemical sensor device.

GOOSE Society of Texas, a group of investors that invest over $50 million into early stage startups, led the $2.6 million round for Lantha Inc. The startup plans to use the funds for finalizing its commercial products, strategic hires, and expand its intellectual property. The device Lantha has created can detect solid-state chemicals, which can be used in a myriad of industries from pharmaceuticals and oil and gas to water and defense.

Jeff Smisek, former United Airlines CEO and founder of investment firm Flight Partners Management LLC, was the GOOSE investor to lead the deal. According to a news release, he will join Lantha's board of directors.

"Lantha is a great example of the GOOSE Society's investment thesis — a company with proprietary and disruptive technology, low capital costs, large addressable markets, speedy product development and high margins which can benefit from the vast experience and contacts of the GOOSE Society's investors," Smisek says in the release. "We are proud to lead this financing and look forward to working closely with Lantha's management and world class scientists as they build a powerhouse in the field-based chemical analysis market."

Simon Humphrey, associate professor of chemistry at the University of Texas, invented the handheld device that is faster, cheaper, and easier to use than traditional tools. Humphrey serves as CTO for the company, and Robert Toker is the CEO and chairman of Lantha.

"We have world class scientists, who are the inventors of our technology, and a strong founding team, and we've attracted a great group of investors led by Jeff Smisek and the GOOSE Society in Houston as well as several prominent investors associated with the University of Texas at Austin," Toker says. "... Partnering with GOOSE has materially improved our chances of success."

The Lantha investment represents the first time GOOSE has funded technology coming out of UT.

"We are excited about expanding GOOSE's investment efforts to UT and look forward to future collaborations and deals," says Samantha Lewis, director at GOOSE. Several high-profile investors from the UT community invested in Lantha's Series A Preferred Stock alongside GOOSE investors.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.