Money moves

Houston investor group leads $2.6 million Series A round for Austin-based chemical sensor startup

GOOSE Society of Texas has invested in a chemical sensor company from Austin. Pexels

A Houston-based investment group has announced funding for a startup out of Austin that has the potential to disrupt multiple industries with its chemical sensor device.

GOOSE Society of Texas, a group of investors that invest over $50 million into early stage startups, led the $2.6 million round for Lantha Inc. The startup plans to use the funds for finalizing its commercial products, strategic hires, and expand its intellectual property. The device Lantha has created can detect solid-state chemicals, which can be used in a myriad of industries from pharmaceuticals and oil and gas to water and defense.

Jeff Smisek, former United Airlines CEO and founder of investment firm Flight Partners Management LLC, was the GOOSE investor to lead the deal. According to a news release, he will join Lantha's board of directors.

"Lantha is a great example of the GOOSE Society's investment thesis — a company with proprietary and disruptive technology, low capital costs, large addressable markets, speedy product development and high margins which can benefit from the vast experience and contacts of the GOOSE Society's investors," Smisek says in the release. "We are proud to lead this financing and look forward to working closely with Lantha's management and world class scientists as they build a powerhouse in the field-based chemical analysis market."

Simon Humphrey, associate professor of chemistry at the University of Texas, invented the handheld device that is faster, cheaper, and easier to use than traditional tools. Humphrey serves as CTO for the company, and Robert Toker is the CEO and chairman of Lantha.

"We have world class scientists, who are the inventors of our technology, and a strong founding team, and we've attracted a great group of investors led by Jeff Smisek and the GOOSE Society in Houston as well as several prominent investors associated with the University of Texas at Austin," Toker says. "... Partnering with GOOSE has materially improved our chances of success."

The Lantha investment represents the first time GOOSE has funded technology coming out of UT.

"We are excited about expanding GOOSE's investment efforts to UT and look forward to future collaborations and deals," says Samantha Lewis, director at GOOSE. Several high-profile investors from the UT community invested in Lantha's Series A Preferred Stock alongside GOOSE investors.

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A research team housed out of the newly launched Rice Biotech Launch Pad received funding to scale tech that could slash cancer deaths in half. Photo via Rice University

A research funding agency has deployed capital into a team at Rice University that's working to develop a technology that could cut cancer-related deaths in half.

Rice researchers received $45 million from the National Institutes of Health's Advanced Research Projects Agency for Health, or ARPA-H, to scale up development of a sense-and-respond implant technology. Rice bioengineer Omid Veiseh leads the team developing the technology as principal investigator.

“Instead of tethering patients to hospital beds, IV bags and external monitors, we’ll use a minimally invasive procedure to implant a small device that continuously monitors their cancer and adjusts their immunotherapy dose in real time,” he says in a news release. “This kind of ‘closed-loop therapy’ has been used for managing diabetes, where you have a glucose monitor that continuously talks to an insulin pump. But for cancer immunotherapy, it’s revolutionary.”

Joining Veiseh on the 19-person research project named THOR, which stands for “targeted hybrid oncotherapeutic regulation,” is Amir Jazaeri, co-PI and professor of gynecologic oncology at the University of Texas MD Anderson Cancer Center. The device they are developing is called HAMMR, or hybrid advanced molecular manufacturing regulator.

“Cancer cells are continually evolving and adapting to therapy. However, currently available diagnostic tools, including radiologic tests, blood assays and biopsies, provide very infrequent and limited snapshots of this dynamic process," Jazaeri adds. "As a result, today’s therapies treat cancer as if it were a static disease. We believe THOR could transform the status quo by providing real-time data from the tumor environment that can in turn guide more effective and tumor-informed novel therapies.”

With a national team of engineers, physicians, and experts across synthetic biology, materials science, immunology, oncology, and more, the team will receive its funding through the Rice Biotech Launch Pad, a newly launched initiative led by Veiseh that exists to help life-saving medical innovation scale quickly.

"Rice is proud to be the recipient of the second major funding award from the ARPA-H, a new funding agency established last year to support research that catalyzes health breakthroughs," Rice President Reginald DesRoches says. "The research Rice bioengineer Omid Veiseh is doing in leading this team is truly groundbreaking and could potentially save hundreds of thousands of lives each year. This is the type of research that makes a significant impact on the world.”

The initial focus of the technology will be on ovarian cancer, and this funding agreement includes a first-phase clinical trial of HAMMR for the treatment of recurrent ovarian cancer that's expected to take place in the fourth year of THOR’s multi-year project.

“The technology is broadly applicable for peritoneal cancers that affect the pancreas, liver, lungs and other organs,” Veiseh says. “The first clinical trial will focus on refractory recurrent ovarian cancer, and the benefit of that is that we have an ongoing trial for ovarian cancer with our encapsulated cytokine ‘drug factory’ technology. We'll be able to build on that experience. We have already demonstrated a unique model to go from concept to clinical trial within five years, and HAMMR is the next iteration of that approach.”

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