This week's innovators to know roundup includes Roberta Schwartz of Houston Methodist, Jani Tuomi of imaware, and Jill Chapman of Insperity. Photos courtesy

Editor's note: In today's Monday roundup of Houston innovators, I'm introducing you to three innovators across industries — including some with COVID-19 news.

Roberta Schwartz, executive vice president of Houston Methodist Hospital

Roberta Schwartz is leading the innovation initiative at Houston Methodist. Courtesy of Houston Methodist

Houston Methodist and its Center for Innovation — led by Roberta Schwartz, executive vice president of Houston Methodist Hospital — has been in the innovation news around Houston in a few ways. First, the health care innovation hub was recognized with the Listies award for corporate innovation and Schwartz accepted the award on behalf of her team.

Last week, Houston Methodist was announced to be on the short list for the COVID-19 vaccine being developed and distributed by Pfizer.

And finally, Schwartz shared details about a new voice technology the hospital has implemented into their operating rooms. The technology uses ambient listening to help surgeons operate hands free from typing or note taking and focus on their patient. Read more.

Jani Tuomi, co-founder of imaware

Jani Tuomi, co-founder of imaware, joins the Houston Innovators Podcast to discuss his company's, early disease screening, COVID-19 testing, and more. Photo courtesy of imaware

As COVID-19 was emerging as an international threat across January and February, Jani Tuomi and his team at imaware — a Houston health tech startup providing at-home testing for chronic conditions — quickly jumped on a way to provide at-home coronavirus testing.

"Right away there was an amazing reception," Tuomi says, adding that big companies were looking to provide their employees on-site training. "There was way more need for testing than supply was available."

Imaware formed strategic partnerships with other Texas companies, including Austin-based startup Wheel — the telemedicine partner. Basically, users take a quick assessment online and if they are high risk, a health care worker is deployed to the patient's site to conduct the test. Once finished, the lab analyzes the sample and telemedicine professionals reach out with results and next steps. Read more and stream the podcast.

Jill Chapman, senior performance consultant with Insperity

Jill Chapman is a senior performance consultant with Insperity. Photo courtesy of Insperity

With Thanksgiving in the rearview, the holiday season is in full swing. And, as some companies in Houston have either partially or completely resumed in-office workdays, businesses might also be looking to spread some holiday cheer around the workspace. Jill Chapman, a senior performance consultant with Insperity, shared in a guest column for InnovationMap her ideas for safe virtual and in-person festivities.

"Business leaders should consider hosting holiday celebrations that honor their employees and align with their ongoing safety protocols," she writes. "For companies that continue to conduct in-person business, holiday celebrations may be safely held outside in Houston's temperate climate. For companies that plan to proceed with virtual celebrations, think outside the box for developing an event that colleagues will enjoy." Read more.

Jani Tuomi, co-founder of imaware, joins the Houston Innovators Podcast to discuss his company's, early disease screening, COVID-19 testing, and more. Photo courtesy of imaware

Houston startup is fostering the future of chronic disease prevention and treatment

HOUSTON INNOVATORS PODCAST EPISODE 59

A family illness got Jani Tuomi thinking — why does treatment of chronic conditions seem like too little, too late? When his brother fell ill, he wondered if more could have been done preemptively.

"The doctors were really good at treating him — but the question I had was why couldn't we have screened for this in advance," Tuomi says on this week's episode if the Houston Innovators Podcast.

He entertained his intuition and started researching, which transitioned into co-founding imaware, a digital health platform that focuses on early identification of chronic conditions — such as diabetes, heart disease, autoimmune issues. What Tuomi and his team found was that these chronic diseases come with biomarkers you can measure before you see symptoms.

Now, imaware exists to provide at-home blood tests for everything from heart health and allergies to thyroid and arthritis screening. And, as COVID-19 was emerging as an international threat across January and February, Tuomi says his team quickly jumped on a way to provide at-home coronavirus testing.

"Right away there was an amazing reception," Tuomi says, adding that big companies were looking to provide their employees on-site training. "There was way more need for testing than supply was available."

Imaware formed strategic partnerships with other Texas companies, including Austin-based startup Wheel — the telemedicine partner. Basically, users take a quick assessment online and if they are high risk, a health care worker is deployed to the patient's site to conduct the test. Once finished, the lab analyzes the sample and telemedicine professionals reach out with results and next steps.

Business for imaware has been booming, and Tuomi has had to scale his business virtually amid the pandemic. Imaware also has an office in Austin, which is focused on the digital side of business.

Looking forward, Tuomi says he's planning on zooming in on the various ways patients were affected by COVID-19, and this summer imaware formed a partnership with Texas A&M University researchers to begin that investigation. Tuomi says he doesn't expect the finalized data until early next year, but what he says the research seems to show is people reacted differently to the disease, and those reactions seem to relate to underlying or chronic conditions — the same conditions imaware has developed early testing for.

"Before COVID, imaware's mission was to identify individuals with chronic conditions earlier, so we're going to double down on our tests," Tuomi says.

Tuomi shares more about the lessons learned from turning around the COVID test so quickly, as well as some of the ways the pandemic has affected the health care industry as a whole. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


Houston-based imaware, which has an at-home COVID-19 testing process, is working with Texas A&M University on researching how the virus affects the human body. Getty Images

Houston health tech startup with at-home COVID-19 test teams up with Texas university for research

be aware

An ongoing medical phenomenon is determining how COVID-19 affects people differently — especially in terms of severity. A new partnership between a Houston-based digital health platform and Texas A&M University is looking into differences in individual risk factors for the virus.

Imaware, which launched its at-home coronavirus testing kit in April, is using its data and information collected from the testing process for this new study on how the virus affects patients differently.

"As patient advocates, we want to aid in the search to understand more about why some patients are more vulnerable than others to the deadly complications of COVID-19," says Jani Tuomi, co-founder of imaware, in a press release. "Our current sample collection process is an efficient way to provide longitudinal prospectively driven data for research and to our knowledge, is the only such approach that is collecting, assessing, and biobanking specimens in real time."

Imaware uses a third-party lab to conduct the tests at patients' homes following the Center for Disease Control's guidelines and protocol. During the test, the medical professional takes additional swabs for the study. The test is then conducted by Austin-based Wheel, a telemedicine group.

Should the patient receive positive COVID-19 results, they are contacted by a representative of Wheel with further instructions. They are also called by a member of a team led by Dr. Rebecca Fischer, an infectious disease expert and epidemiologist and laboratory scientist at the Texas A&M University School of Public Health, to grant permission to be a part of the study.

Once a part of the study, the patient remains in contact with Fischer's team, which tracks the spread and conditions of the virus in the patient. One thing the researchers are looking for is the patients' responses to virus complications caused by an overabundance of cytokines, according to the press release. Cytokines are proteins in the body that fight viruses and infections, and, if not working properly, they can "trigger an over-exuberant inflammatory response" that can cause potentially deadly issues with lung and organ failure or worse, per the release.

"We believe strongly in supporting this research, as findings from the field can be implemented to improve clinical processes-- helping even more patients," says Wheel's executive medical director, Dr. Rafid Fadul.

Houston-based Imaware has launched at-home testing that can identify if the patient has — or even had — the coronavirus. Photo via imaware.health

Houston health tech startup launches game-changing, at-home coronavirus testing

be aware

Politicians, scientists, public health officials, and others continue to stress the need for widespread testing to tame the spread of the novel coronavirus.

Houston-based startup Imaware, an at-home health testing platform, recently rolled out an at-home coronavirus test for high-risk people, such as someone with both a fever and recent exposure to someone infected with the virus. Now, it's gearing up to offer an at-home test designed to spot the presence of coronavirus antibodies in your blood.

Experts view antibody testing as a key to corralling the virus and rebooting the virus-crushed U.S. economy. However, some skeptics fear the benefits of antibody testing are being oversold.

As explained by Health.com, a nasal swab test can detect a coronavirus infection. But a blood test can pinpoint whether a person has been exposed to the novel coronavirus, which causes the COVID-19 respiratory illness, and might now be immune to it.

Jani Tuomi, co-founder of Imaware, says his company is working with the U.S. Centers for Disease Control and Prevention (CDC) and U.S. Food and Drug Administration (FDA) on approval of Imaware's antibody test. The in-home blood test might be available as early as May.

"We're still trying to make sure that everything checks out and validation is completed," Tuomi says, "but it looks like it's headed in the right direction."

In early April, the FDA approved the first test in the U.S. to detect coronavirus antibodies.

Tuomi says the process for Imaware's coronavirus antibody test will be similar to the one for the coronavirus detection test. Both tests, for instance, will be administered by licensed clinicians.

Here's how the basic test works.

To request a coronavirus test, someone completes a 10-question assessment at imaware.health. Austin-based startup Wheel, Imaware's telemedicine partner, created the online assessment.

Someone is given the go-ahead for testing if, as determined by a licensed health care professional, he or she falls into certain risk categories. For instance, somebody who's been exposed to a person with coronavirus and is over 60 years old would be approved for a test.

If health insurance covers the test or a patient pays for it entirely out of pocket, the test costs $135. (The home-based antibody test will cost about $120 to $125.) Public health agencies, including the Houston Health Department, can authorize a test for someone who can't afford it.

A trained health care professional goes to a patient's home to collect a test sample (by taking a nasal swab for the coronavirus test or drawing blood for the antibody test). A CDC-authorized lab then tests the sample. If needed, a board-certified health care professional can provide post-diagnosis care.

Results of a coronavirus test typically are available within three days. Tuomi says he hopes the results window for the test can be narrowed to between one and two days by the end of April.

"As a patient-advocate company, we are uniquely poised to be part of the testing shortage solution in Texas," Tuomi says in a March 23 release announcing the Imaware coronavirus swab test. "Our online platform, telemedicine partner, and in-home sample collection empower patients to take control of their health and access COVID-19 testing from the comfort of home."

Founded in 2018, Imaware employs 14 people. Others involved in the testing process, such as in-home testing clinicians and telemedicine experts, work for third-party partners. As the company adds to its testing lineup, Tuomi envisions the workforce rising to around 30 to 40 people by the end of 2020.

Earlier this year, Imaware (whose legal name is Microdrop LLC) had concentrated on home-based remote screening and monitoring for conditions like celiac disease and heart disease. But once it became clear that the coronavirus pandemic would be striking the U.S., the company shifted to coronavirus testing and, now, to antibody testing.

Before Imaware jumped into coronavirus testing, Tuomi performed a swab test on himself and realized that it wasn't feasible for anyone to do self-testing. On top of that, evidence surfaced that self-collection of test samples was producing a lot of false-negative results, he says. Subsequently, the federal government blocked self-testing for the coronavirus.

Today, health care professionals handle Imaware's at-home coronavirus testing and will handle the at-home antibody testing. The testing initially launched in Houston then expanded to the rest of Texas.

Tens of thousands of people have done coronavirus self-assessments through Imaware's online tool, Tuomi says. Far fewer people — in the hundreds — have actually fallen into high-risk categories based on the self-assessments and then have qualified for testing.

Tuomi says that as testing capabilities grow, Imaware will be able to accommodate people who fit into medium-risk coronavirus categories. Also, the company plans to offer its coronavirus test in states that neighbor Texas. Imaware hopes to provide its antibody test throughout the U.S.

In tandem with the public testing, Imaware teamed up with Austin-based energy tech startup RigUp to enable daily coronavirus screening at oil and gas jobsites. Imaware and RigUp are piloting the screening with several RigUp customers; they hope it eventually can be supplied nationwide.

"A cornerstone of the Imaware solution is the patient-centric approach offering superior telemedicine care from diagnosis to recovery," Tuomi says.

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Rice lands $15M U.S. Army award to launch next-gen wireless research center

defense funding

The U.S. Army Research Office has awarded Rice University $15 million to establish a new center for next-generation sensing and communications.

The five-year research center—dubbed the Center for Large Aperture Secure Sensing, Imaging and Communications (CLASSIC)—will unite researchers from universities and national laboratories to develop advanced antenna technologies for future wireless systems. Edward Knightly, the Sheafor-Lindsay Professor of Electrical and Computer Engineering at Rice, will lead the center that “combines expertise in wireless networking, antennas, radar, artificial intelligence, circuits and physics to address growing demands on wireless systems,” according to Rice.

“The challenges we’re tackling require advances that span physics, hardware, communications and computing," Knightly said in a news release. “By combining those strengths in a single center, we can accelerate the development and demonstration of technologies that would not be possible through individual efforts alone.”

Joining Knightly will be Ashutosh Sabharwal of Rice, Sensen Li of the University of Texas at Austin, Hou-Tong Chen of Los Alamos National Laboratory, Danijela Cabric of UCLA, Josep M. Jornet and Tommaso Melodia of Northeastern University, Daniel M. Mittleman of Brown University, and Willie Padilla of Duke University.

Industry partners include Booz Allen Hamilton, Intel, Keysight, Lockheed Martin, MITRE, Northrop Grumman, Qualcomm and Raytheon.

CLASSIC researchers will investigate how large-scale antenna arrays (ELSAAs) can expand the capabilities of wireless systems where technology is limited.

ELSAAs use thousands of coordinated antenna elements to direct radio waves. Researchers aim to develop ways to use the technology to help maintain steady communication when signals are blocked or disrupted and to detect and generate detailed images of concealed objects.

Along with ELSAAs, the center will work to develop sensing techniques for threat detection, study wireless jamming and build resilient high-speed wireless networks. Researchers will ultimately validate the technology in labs and via drone-based field trials.

CLASSIC will also work on developing an AI-driven modeling framework that will simulate complex electromagnetic environments in real time.

“This award demonstrates Rice’s leadership in tackling complex national research challenges through collaboration across disciplines and institutions,” David Sholl, executive vice president for research at Rice, added in the release.

UH scores $18M NIH grant for chronic disease research

research funding

The University of Houston has received a coveted $18.8 million grant from the National Institutes of Health to launch a program to address the root causes of chronic disease.

Only 22 institutions nationwide receive this NIH award, and the 5-year process aligns with the newly established UH Health’s mission to expand healthcare innovations in Texas and beyond. The initiative will be housed in the UH Population Health department.

"This generous funding allows us to directly confront the root causes of chronic illness that place a heavy burden on so many families," Dr. Jonathan McCullers, vice president for health affairs at UH, said in a news release. "With the recent launch of UH Health, we have an unprecedented opportunity to translate scientific discovery into healthier outcomes for our communities by bringing together experts from across the university to improve health where it matters most.”

Through the program, UH researchers from different areas of expertise will work together to address the challenges of chronic illness by looking at biological, social and behavioral factors.

According to the university, chronic diseases like heart disease, diabetes, strokes and others are the leading cause of illness, disability and death in the U.S. They account for 90 percent of the nation’s $5.3 trillion in annual healthcare spending.

Bettina Beech, chief of population health and translational science at UH, serves as principal investigator for the program.

“Chronic disease management largely happens during the 8,700 hours each year that people are not visiting their healthcare provider,” Beech added in the news release. “While healthcare is indispensable, it only accounts for 20 percent of how health is created — genetics accounts for another 10 percent, and the other 70 percent is determined by behavior, social conditions and environment.”

With the funds from the grant, UH will also be able to expand research infrastructure, add to community partnerships, support complementary research, and invest in early-career investigators, according to the news release. UH also aims to develop solutions that could help ease the economic burden of chronic disease.