Reda Hicks (left) of GotSpot Inc, Ghazal Qureshi (center) of Idea Lab Kids, and Abbey Donnell of Work & Mother are this week's innovators to know. Courtesy photos

Another Monday means another set of innovators to know. This one focuses on a few female startup leaders changing the game in the commercial real estate and education industries.

Reda Hicks, founder and CEO of GotSpot Inc.

Reda Hicks create GotSpot — a digital tool that helps connect people with commercial space with people who need it. Courtesy of GotSpot

Turns out, Hurricane Harvey was the big push Reda Hicks needed to create her startup, GotSpot Inc., the Airbnb of commercial real estate.

"It was really Harvey and having so many people desperate to find space for emergency purposes that made me realize there are so many contexts in which people need space right away for something specific," she says. "Certainly the primary user is the entrepreneur trying to grow their business, but there are so many other reasons why a community would need better access to the space it already has."

Hicks, a lawyer by trade, now juggles startup life, being a wife and mom, and her full-time legal career. Read the rest of the story here.

Ghazal Qureshi, founder of Idea Lab Kids

Ghazal Qureshi wanted to engage her own kids in educational activities. Now, her programing has expanded worldwide. Courtesy of Idea Lab Kids

At first, Ghazal Qureshi just wanted to find her kids a quality after school educational program. When she couldn't, she decided to make something herself. Now, it's a franchised company with locations worldwide.

"From the beginning, we were never restricted by trying to make money. It was a passion project only," Qureshi says.

IDEA Lab Kids, an education program focused on STEAM, which stands for science, technology, engineering, arts, and math, has 18 locations in Houston, and, two years ago, she expanded the brand into a franchise business — the Idea Lab International Franchise Company. Read the rest of the story here.

Abbey Donnell, founder of Work & Mother

Abbey Donnell's startup, Work & Mother, provides a new way for new moms to pump breast milk during the workday. Courtesy of Work & Mother

When Abbey Donnell heard horror stories from some friends who recently returned to work after giving birth, she had an idea. What if new moms had a stylish, spa-like lactation experience during the workday that was less inconvenient and, well, awkward.

"There were constant stories about [women] being told the use the IT closet, or the conference room, or the bathroom or their cars," Donnell says. "Some of them were pretty big oil and gas firms companies that should've had the resources and space to do better than that."

Donnell founded Work & Mother, a boutique pumping and wellness center, and opened the first location in downtown Houston in 2017 and is planning its second downtown location. Read the rest of the story here.

Ghazal Qureshi wanted to engage her own kids in educational activities. Now, her programing has expanded worldwide. Courtesy of Idea Lab Kids

Houston entrepreneur expands her passion project to international franchise business

After school program

Ghazal Qureshi was looking for a way to engage her children in after school education. After failing to find anything that existed, she started brainstorming a new, engaging education model.

"From the beginning, we were never restricted by trying to make money. It was a passion project only," Qureshi says.

Qureshi turned her passion project into IDEA Lab Kids, an education program focused on STEAM, which stands for science, technology, engineering, arts, and math. She opened 18 locations in Houston, and, two years ago, she expanded the brand into a franchise business — the Idea Lab International Franchise Company. Now the company has locations across the United States and around the world.

The passion she had at Idea Lab's start has become an essential part of each franchise location, and Qureshi is seeking out franchise partners just as passionate to "take our idea far and wide," she says

"We are educating the future innovators and entrepreneurs of tomorrow," Qureshi says.

Front of class
Idea Lab locations around the country are engaging children from pre-k through high school in hands-on projects that reflect their own interests. Qureshi's goal is to take learning beyond the classroom.

"Anytime kids are out of school, Idea Lab is in session," says Qureshi.

Qureshi recalls that when fidget spinners were dubbed a distraction in traditional schools, children in Idea Labs were studying how the toy's motor operates, and were actually creating their own spinners using 3-D printers.

"Idea Lab picks up the slack in areas that traditional schools are unequipped to excel," explains Qureshi.

Small class sizes, and an array of technology and materials give children attending their after-school programs, weekend workshops, summer camps, or birthday parties the opportunity to use technologies that they may not otherwise be exposed to.

"You'll never see our kids just listening to lectures; it's all project-based," she says. "We are training them for the skills they will need for their jobs in the next 5, 10, 15 years."

Getting the ball rolling
Qureshi began Idea Lab in Houston seven years ago, inspired by the challenge of raising her own children with quality STEAM education.

"My background is in IT," she explains, "but I felt like I was really missing out on being part of my children's lives, so I decided to leave corporate life. I put my energy into my kids and finding the best educational opportunities for them. But I realized there was a void."

With the need to build and create inherent in her personality, Qureshi quickly saw her new company begin to grow.

Qureshi's oldest son, now headed for college, is a big part of her personal success story with her Idea Lab program. She saw his creativity and motivation for learning blossom throughout his years of Idea Lab classes such as coding movie production, or robotics. Qureshi is excited that Idea Lab still provides the same educational boost to thousands of children that she saw so profoundly impact her son.

Especially after her experience in starting her own business, Qureshi wants to encourage future entrepreneurs through Idea Lab's entrepreneurship program. Projects that children develop within this program embody all aspects of the blended learning STEAM model, plus a good measure of critical thinking and creativity. Children may build their own restaurant, and as founders, managers, and chefs, they must create menus and pricing, recipes with units of measure, 3-D printed objects such as spoons, and navigate other realities of owning a small business. Equally as important, children must learn to collaborate toward common goals, and utilize each other's strengths.

Ready for graduation
The company is actively looking for expansion opportunities and prospective franchisees.

"The ideal franchisee," Qureshi says, "is someone who 'gets' the void in the education, understands the education industry, or has kids for whom they haven't been able to find great programs for."

Thus far, Idea Lab has 52 assigned territories in the United States, six in Canada, one opening soon in Ecuador, and talks are beginning with other country partners. Although for Qureshi, founding Idea Lab from the ground up required countless hours of dedication.,

"When you buy a franchise, everything is all worked out for you, all the hardship has been taken out of it, as someone has already done the trial and error," Qureshi says.

Idea Lab provides materials and models for everything from tested and vetted curriculum to implementation of their programs, making it as easy as possible to hit the ground running.

As Idea Lab keeps its finger on the pulse of the next wave of innovation to motivate children, and grow their business, they are looking for partners who are interested in helping to provide a creative education to the community.

As Qureshi always tells parents, "with a little bit of a push, you'll be surprised by how many new things kids can learn through their own exploration, if given the opportunity."

Three female-founded companies pitched to potential investors at The Cannon. Here's why they are ones to watch. Courtesy photos

3 female Houston startup founders to watch in 2019

Leading ladies

The Lone Star State has been deemed a great place for female entrepreneurs to get their feet wet, and Houston's ecosystem is full of these leading ladies. At a pitch party at The Cannon, a coworking space in West Houston, over 100 guests, including Cannon Ventures investors and Cannon members, gathered to hear three of these female founders pitch their companies.

From DNA dating and smart pillboxes to an educational franchise company, these three female-led institutions are ones to watch this year. Here's why.

X&Y Technologies

Brittany Barreto wants X&Y Technologies to be known for its science-based dating expertise. Karla Martin/Pheramor

Now is the time to have a DNA-based technology company, says Brittany Barreto, CEO and co-founder of X&Y Technologies. She launched her genetics-based data app over two years ago, and now she's expanding the brand to include a couples compatibility test and B-to-B software-as-a-service feature, so that other dating apps can utilize her technology.

"Our traction with the dating app was a fantastic way to prove that we are the thought leaders, we have the infrastructure, and we have the algorithm and we've proven that the market is ready to buy a DNA kit to find love," she says in her pitch.

With fundraising plans in 2019, Barreto hopes to launch the expanded company, and says she has already seen a lot of interest in both of the new DNA-based products. Read more about Pheramor's national growth, the X&Y expansion, and how Barreto got her start.

IDEA Lab Kids

Ghazal Qureshi pitched her education franchise company, IDEA Lab Kids, and discussed her plans to double its presence in 2019. Natalie Harms/InnovationMap

Six years ago, when Ghazal Qureshi wanted an after school program for her kid and their diverse interests, she created it. Now, the interactive programming that focuses on the science, technology, engineering, arts and math activities for kids is a growing franchise opportunity. After launching the franchise model in February 2017, IDEA Lab Kids already has 10 locations, with seven coming on board within the next few months — including a location in Ecuador.

"In 2019, we're looking to double the number of campuses," Qureshi says in her pitch.

What makes IDEA Lab different from its competitors, she says, is the interactive and diversified curriculum that engages all children.

"We know that kids have limited attention spans theses days," Qureshi says. "New technologies and methods are needed every day in order to grasp that attention span, and that is what we are really good at. At any given day, there are drones flying, augmented reality, cooking classes, and more are happening under the roof of an IDEA Lab campus."

In addition to expanding its presence, Qurshi has worked to roll our new products, such as a coding club, updated website registration tools

EllieGrid

Regina Vatterott is thinking outside the pillbox with her startup, EllieGrid. Courtesy of EllieGrid

When she was in college, Regina Vatterott fainted on her way to lunch. She had lapsed on taking her medicine and vitamins, which caused an imbalance in her health. She was using a traditional pillbox that was tacky and a pain to organize and starting thinking about a product that was more stylish and used smart technology. She and her cofounders created EllieGrid, a sleek pillbox that syncs to your phone to send you messages when its time to take your meds and allows for an easier organization process.

EllieGrid's reception has been great, and the company is expanding to provide users new tools and technology. For instance, EllieGrid is starting to learn more about when its users take its medicine, which can translate to partnerships with insurence companies that currently pay pharmacies to check in with patients who haven't picked up their medicine.

"For us, Ellie is just the start," Vatterott says in an interview with InnovationMap. "We want to develop more health and wellness accessories that are traditionally known to be medical devices."

Large companies are taking interest in the Houston-based startup. Over the past three weeks, Best Buy, Walmart, CVS Health, and Pelion all reached out and expressed interest in the company, some actually placing orders and setting up trials.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."