3 Houston female entrepreneurs to know this week

Who's who

Reda Hicks (left) of GotSpot Inc, Ghazal Qureshi (center) of Idea Lab Kids, and Abbey Donnell of Work & Mother are this week's innovators to know. Courtesy photos

Another Monday means another set of innovators to know. This one focuses on a few female startup leaders changing the game in the commercial real estate and education industries.

Reda Hicks, founder and CEO of GotSpot Inc.

Reda Hicks create GotSpot — a digital tool that helps connect people with commercial space with people who need it. Courtesy of GotSpot

Turns out, Hurricane Harvey was the big push Reda Hicks needed to create her startup, GotSpot Inc., the Airbnb of commercial real estate.

"It was really Harvey and having so many people desperate to find space for emergency purposes that made me realize there are so many contexts in which people need space right away for something specific," she says. "Certainly the primary user is the entrepreneur trying to grow their business, but there are so many other reasons why a community would need better access to the space it already has."

Hicks, a lawyer by trade, now juggles startup life, being a wife and mom, and her full-time legal career. Read the rest of the story here.

Ghazal Qureshi, founder of Idea Lab Kids

Ghazal Qureshi wanted to engage her own kids in educational activities. Now, her programing has expanded worldwide. Courtesy of Idea Lab Kids

At first, Ghazal Qureshi just wanted to find her kids a quality after school educational program. When she couldn't, she decided to make something herself. Now, it's a franchised company with locations worldwide.

"From the beginning, we were never restricted by trying to make money. It was a passion project only," Qureshi says.

IDEA Lab Kids, an education program focused on STEAM, which stands for science, technology, engineering, arts, and math, has 18 locations in Houston, and, two years ago, she expanded the brand into a franchise business — the Idea Lab International Franchise Company. Read the rest of the story here.

Abbey Donnell, founder of Work & Mother

Abbey Donnell's startup, Work & Mother, provides a new way for new moms to pump breast milk during the workday. Courtesy of Work & Mother

When Abbey Donnell heard horror stories from some friends who recently returned to work after giving birth, she had an idea. What if new moms had a stylish, spa-like lactation experience during the workday that was less inconvenient and, well, awkward.

"There were constant stories about [women] being told the use the IT closet, or the conference room, or the bathroom or their cars," Donnell says. "Some of them were pretty big oil and gas firms companies that should've had the resources and space to do better than that."

Donnell founded Work & Mother, a boutique pumping and wellness center, and opened the first location in downtown Houston in 2017 and is planning its second downtown location. Read the rest of the story here.

Ghazal Qureshi wanted to engage her own kids in educational activities. Now, her programing has expanded worldwide. Courtesy of Idea Lab Kids

Houston entrepreneur expands her passion project to international franchise business

After school program

Ghazal Qureshi was looking for a way to engage her children in after school education. After failing to find anything that existed, she started brainstorming a new, engaging education model.

"From the beginning, we were never restricted by trying to make money. It was a passion project only," Qureshi says.

Qureshi turned her passion project into IDEA Lab Kids, an education program focused on STEAM, which stands for science, technology, engineering, arts, and math. She opened 18 locations in Houston, and, two years ago, she expanded the brand into a franchise business — the Idea Lab International Franchise Company. Now the company has locations across the United States and around the world.

The passion she had at Idea Lab's start has become an essential part of each franchise location, and Qureshi is seeking out franchise partners just as passionate to "take our idea far and wide," she says

"We are educating the future innovators and entrepreneurs of tomorrow," Qureshi says.

Front of class
Idea Lab locations around the country are engaging children from pre-k through high school in hands-on projects that reflect their own interests. Qureshi's goal is to take learning beyond the classroom.

"Anytime kids are out of school, Idea Lab is in session," says Qureshi.

Qureshi recalls that when fidget spinners were dubbed a distraction in traditional schools, children in Idea Labs were studying how the toy's motor operates, and were actually creating their own spinners using 3-D printers.

"Idea Lab picks up the slack in areas that traditional schools are unequipped to excel," explains Qureshi.

Small class sizes, and an array of technology and materials give children attending their after-school programs, weekend workshops, summer camps, or birthday parties the opportunity to use technologies that they may not otherwise be exposed to.

"You'll never see our kids just listening to lectures; it's all project-based," she says. "We are training them for the skills they will need for their jobs in the next 5, 10, 15 years."

Getting the ball rolling
Qureshi began Idea Lab in Houston seven years ago, inspired by the challenge of raising her own children with quality STEAM education.

"My background is in IT," she explains, "but I felt like I was really missing out on being part of my children's lives, so I decided to leave corporate life. I put my energy into my kids and finding the best educational opportunities for them. But I realized there was a void."

With the need to build and create inherent in her personality, Qureshi quickly saw her new company begin to grow.

Qureshi's oldest son, now headed for college, is a big part of her personal success story with her Idea Lab program. She saw his creativity and motivation for learning blossom throughout his years of Idea Lab classes such as coding movie production, or robotics. Qureshi is excited that Idea Lab still provides the same educational boost to thousands of children that she saw so profoundly impact her son.

Especially after her experience in starting her own business, Qureshi wants to encourage future entrepreneurs through Idea Lab's entrepreneurship program. Projects that children develop within this program embody all aspects of the blended learning STEAM model, plus a good measure of critical thinking and creativity. Children may build their own restaurant, and as founders, managers, and chefs, they must create menus and pricing, recipes with units of measure, 3-D printed objects such as spoons, and navigate other realities of owning a small business. Equally as important, children must learn to collaborate toward common goals, and utilize each other's strengths.

Ready for graduation
The company is actively looking for expansion opportunities and prospective franchisees.

"The ideal franchisee," Qureshi says, "is someone who 'gets' the void in the education, understands the education industry, or has kids for whom they haven't been able to find great programs for."

Thus far, Idea Lab has 52 assigned territories in the United States, six in Canada, one opening soon in Ecuador, and talks are beginning with other country partners. Although for Qureshi, founding Idea Lab from the ground up required countless hours of dedication.,

"When you buy a franchise, everything is all worked out for you, all the hardship has been taken out of it, as someone has already done the trial and error," Qureshi says.

Idea Lab provides materials and models for everything from tested and vetted curriculum to implementation of their programs, making it as easy as possible to hit the ground running.

As Idea Lab keeps its finger on the pulse of the next wave of innovation to motivate children, and grow their business, they are looking for partners who are interested in helping to provide a creative education to the community.

As Qureshi always tells parents, "with a little bit of a push, you'll be surprised by how many new things kids can learn through their own exploration, if given the opportunity."

Three female-founded companies pitched to potential investors at The Cannon. Here's why they are ones to watch. Courtesy photos

3 female Houston startup founders to watch in 2019

Leading ladies

The Lone Star State has been deemed a great place for female entrepreneurs to get their feet wet, and Houston's ecosystem is full of these leading ladies. At a pitch party at The Cannon, a coworking space in West Houston, over 100 guests, including Cannon Ventures investors and Cannon members, gathered to hear three of these female founders pitch their companies.

From DNA dating and smart pillboxes to an educational franchise company, these three female-led institutions are ones to watch this year. Here's why.

X&Y Technologies

Brittany Barreto wants X&Y Technologies to be known for its science-based dating expertise. Karla Martin/Pheramor

Now is the time to have a DNA-based technology company, says Brittany Barreto, CEO and co-founder of X&Y Technologies. She launched her genetics-based data app over two years ago, and now she's expanding the brand to include a couples compatibility test and B-to-B software-as-a-service feature, so that other dating apps can utilize her technology.

"Our traction with the dating app was a fantastic way to prove that we are the thought leaders, we have the infrastructure, and we have the algorithm and we've proven that the market is ready to buy a DNA kit to find love," she says in her pitch.

With fundraising plans in 2019, Barreto hopes to launch the expanded company, and says she has already seen a lot of interest in both of the new DNA-based products. Read more about Pheramor's national growth, the X&Y expansion, and how Barreto got her start.

IDEA Lab Kids

Ghazal Qureshi pitched her education franchise company, IDEA Lab Kids, and discussed her plans to double its presence in 2019. Natalie Harms/InnovationMap

Six years ago, when Ghazal Qureshi wanted an after school program for her kid and their diverse interests, she created it. Now, the interactive programming that focuses on the science, technology, engineering, arts and math activities for kids is a growing franchise opportunity. After launching the franchise model in February 2017, IDEA Lab Kids already has 10 locations, with seven coming on board within the next few months — including a location in Ecuador.

"In 2019, we're looking to double the number of campuses," Qureshi says in her pitch.

What makes IDEA Lab different from its competitors, she says, is the interactive and diversified curriculum that engages all children.

"We know that kids have limited attention spans theses days," Qureshi says. "New technologies and methods are needed every day in order to grasp that attention span, and that is what we are really good at. At any given day, there are drones flying, augmented reality, cooking classes, and more are happening under the roof of an IDEA Lab campus."

In addition to expanding its presence, Qurshi has worked to roll our new products, such as a coding club, updated website registration tools

EllieGrid

Regina Vatterott is thinking outside the pillbox with her startup, EllieGrid. Courtesy of EllieGrid

When she was in college, Regina Vatterott fainted on her way to lunch. She had lapsed on taking her medicine and vitamins, which caused an imbalance in her health. She was using a traditional pillbox that was tacky and a pain to organize and starting thinking about a product that was more stylish and used smart technology. She and her cofounders created EllieGrid, a sleek pillbox that syncs to your phone to send you messages when its time to take your meds and allows for an easier organization process.

EllieGrid's reception has been great, and the company is expanding to provide users new tools and technology. For instance, EllieGrid is starting to learn more about when its users take its medicine, which can translate to partnerships with insurence companies that currently pay pharmacies to check in with patients who haven't picked up their medicine.

"For us, Ellie is just the start," Vatterott says in an interview with InnovationMap. "We want to develop more health and wellness accessories that are traditionally known to be medical devices."

Large companies are taking interest in the Houston-based startup. Over the past three weeks, Best Buy, Walmart, CVS Health, and Pelion all reached out and expressed interest in the company, some actually placing orders and setting up trials.

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Rice, Houston Methodist developing soft 'sleep cap' for brain health research

Researchers and scientists at Rice University and Houston Methodist are developing a “sleep cap” that aims to protect the brain against dementia and other similar diseases by measuring and improving deep sleep.

The project is a collaboration between Rice University engineering professors Daniel Preston, Vanessa Sanchez and Behnaam Aazhang; and Houston Methodist neurologist Dr. Timea Hodics and Dr. Gavin Britz, director of the Houston Methodist Neurological Institute and chairman of the Department of Neurosurgery.

According to Rice, deep sleep is essential for clearing waste products from the brain and nightly “cleaning cycles” help remove toxic proteins. These toxic proteins, like amyloids, can accumulate during the day and are linked to Alzheimer’s disease and other neurological issues.

Aazhang, director of the Rice Neuroengineering Initiative, and his team are building a system that not only tracks the brain’s clearing process but can also stimulate it, improving natural mechanisms that protect against neurodegeneration.

Earlier proof-of-concept versions of the caps successfully demonstrated the promise of this approach; however, they were rigid and uncomfortable for sleep.

Preston and Sanchez will work to transform the design of the cap into a soft, lightweight, textile-based version to make sleep easier, while also allowing the caps to be customizable and tailored for each patient.

“One of the areas of expertise we have here at Rice is designing wearable devices from soft and flexible materials,” Preston, an assistant professor of mechanical engineering, said in a news release. “We’ve already shown this concept works in rigid device prototypes. Now we’re building a soft, breathable cap that people can comfortably wear while they sleep.”

Additionally, the research team is pursuing ways to adapt their technology to measure neuroinflammation and stimulate the brain’s natural plasticity. Neuroinflammation, or swelling in the brain, can be caused by injury, stroke, disease or lifestyle factors and is increasingly recognized as a driver of neurodegeneration, according to Rice.

“Our brain has an incredible ability to rewire itself,” Aazhang added in the release. “If we can harness that through technology, we can open new doors for treating not just dementia but also traumatic brain injury, stroke, Parkinson’s disease and more.”

The project represents Rice’s broader commitment to brain health research and its support for the Dementia Prevention Research Institute of Texas (DPRIT), which passed voter approval last week. The university also recently launched its Rice Brain Institute.

As part of the project, Houston Methodist will provide access to clinicians and patients for early trials, which include studies on patients who have suffered traumatic brain injury and stroke.

“We have entered an era in neuroscience that will result in transformational cures in diseases of the brain and spinal cord,” Britz said in the release. “DPRIT could make Texas the hub of these discoveries.”

Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.

Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.

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