Non-Houstonian identifies why the Bayou City is prime for a tech and startup boom

Guest column

What does Houston's tech scene look like from an outsider's perspective? Ripe for success, according to this guest article. Getty Images

Houston might be known abroad as the Space City, but it's got a lot more to offer than interstellar exploration. As we continue toward the second half 2020 — even in light of the COVID-19 crisis, Houston is attracting the best talent, tech, and businesses around — and with good reason.

Here we look at why Houston is such an attractive prospect for enterprise in 2020.

More bang for your buck

While the likes of New York or Los Angeles are established places to launch and grow a business, they are expensive. But in Houston, your important dollar goes a long way.

The cost of living in Houston is around 35 percent lower than in New York. Consequently, cash-strapped but ambitious graduates flock to Houston to enjoy a better (and more affordable) quality of life.

For startups looking to gradually and sustainably grow in their first year (and succeed), Houston is an attractive place to start. They get more bang for their buck, so they can focus on growing their business without paying through the nose for expensive office space (and staff).

It's a beautiful, historic city

Founded in 1836, Houston has a long and rich history, and its aesthetics perfectly represents that — something Houstonians and Texans don't take enough time to recognize usually. Its architecture is a healthy mix of historic and modern.

Downtown Houston features gorgeous old buildings spreading out from Allen's Landing. Its residential architecture too offers some stunning mansions, as well as some rustic row houses. As the city developed throughout history, its skyline has grown to include some breathtaking skyscrapers, including the Heritage Plaza and the JPMorgan Chase Tower — one of the tallest composite buildings in the world.

Looking beyond architecture, Houston offers plenty of green spaces to enjoy. Hermann Park is an impressive 445 acres, and acts as a community space for the entire city. If you want somewhere to run a few miles before heading to work, Memorial Park offers plenty of open space and trails to take advantage of too.

Looks aren't everything, of course. But with the rich sprawl of Houston all around you, they certainly help.

There's a thriving coworking scene

Houston is home to dozens of stellar coworking spaces — with more opening regularly. There's a few WeWork outposts from the Galleria area to The Woodlands, as well as home-grown spaces like The Cannon, Station Houston, and Wicowork, where businesses from virtually every industry come together to work and collaborate.

These spaces form part of a thriving startup scene with plenty of scope for networking and collaborating. Growing a business is easier when you're doing it alongside others, and Houston's coworking spaces offer a fertile ground for meeting and sharing inspiration.

It's not all about established businesses either. Houston is also the perfect place for individuals to launch a creative side hustle, with a thriving scene of artistic self-starters and passionate solopreneurs available to draw upon for inspiration. These coworking spaces provide the perfect place to meet like-minded individuals and get your vision further.

Although COVID-19 has affected coworking spaces, the crisis has pushed coworking to provide virtual resources, which will only benefit coworkers across companies.

Choose from a great pool of talent

Every growing business needs the best and brightest talent to join its ranks and help it succeed. Thankfully, Houston is home to some of the finest universities in the state. The University of Houston and Rice University produce plenty of smart, driven graduates looking to make their mark on the chosen industry.

These universities also have a close relationship with local startups too. Each has its own startup accelerator to help small enterprises get ahead. UH's RED Labs has helped launch dozens of companies since its inception in 2013, and Rice University's OwlSpark has 54 startups to its name to date.

Consequently, plenty of businesses are looking to Houston to seek growth and attract top talent. With such a wide pool of talent on tap, startups and growing businesses alike will have their pick of the crop.

Everything's bigger in Texas, and Houston is no exception. With a growing pool of bright talent, a stellar startup scene, and beautiful surroundings to match, Houston is the top destination for talent and business in 2020.

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Kayleigh Alexandra is an entrepreneur and writer at Micro Startups based in the United Kingdom.
From Houston's fastest-growing companies and three female innovators to know to coronavirus tracking tool and COVID-19 resources for startups, here's what you're reading this week. Pexels

5 most popular innovation stories in Houston this week

WHAT'S TRENDING

Editor's note: The Houston innovation ecosystem is joining together — virtually — to provide health and resources to those affected by coronavirus — from fashion entrepreneurs designing face masks to 3D printers making personal protective equipment. Both non-COVID-19 news, like Houston's fastest-growing companies and three female innovators to know, and virus-related articles, like a coronavirus tracking tool and resources for startups, trended this week.

3 female Houston innovators to know this week

This week's innovators to know are Allie Danziger, Sylvia Kampshoff, and Brittany Barreto. Courtesy photos

This one's for the ladies. InnovationMap's weekly roundup of innovators to know features three female founders — one is offering her advice on crisis communications, one is innovating the at-home workout, and one is planning on making Houston a city for femtech. Continue reading.

Houston startups turn to digital pitches during coronavirus shutdown

Three Houston-based startups logged on to pitch digitally this week since SXSW was canceled. Getty Images

When SXSW canceled a couple weeks ago, event organizers were sent into a frantic scramble of how to salvage some aspect of their plans while also balancing lost deposits, canceled travel, and so much more.

Three pitch events associated with SXSW and featuring Houston startups went on in a digital capacity, and the social distancing has only just began. Michele Price who leads Startup Grind Houston says the Google-backed organization with locations everywhere is aware of the need for digital networking options. Continue reading.

Houston startup creates COVID-19 tracking tool

A Houston startup has created a web tool for tracking the coronavirus. Pexels

AHouston tech startup has created a web application to give the residents of Harris County all the local information on COVID-19 in the palm of their hand.

Predictive Solutions uses a map tool to indicate the county's nearby testing locations as well as cases that have been self reported in the area through the tool. While not trying to be comprehensive, the website is trying to track trends with the disease. Continue reading.

These are the 5 fastest-growing companies in Houston, according to a recent report

Inc. magazine has identified the fastest-growing companies in Houston. Nick Bee/Pexels

Bellaire-based startup Instafuel is pumping up its revenue in a big way.

Among the 250 fastest-growing companies in Texas identified by Inc. magazine, Instafuel tops the group of businesses based in the Houston metro area and ranks fifth statewide. Houston-based companies make up 68 of the state's fast-growing companies — eight Houston companies make up the top 25 list. Continue reading.

4 resources for Houston startups and small businesses during COVID-19 shutdown

Small businesses and startups are likely to hurt — and hurt bad — from COVID-19's affect on the economy. Here are some resources to get support. Photo by Hero Images

It's a trying time for the world, and Houston small businesses and startups have been put in a difficult spot. From having to work remotely or being forced to close or scale back operations due to mandates from the government, entrepreneurs are having to figure out their new normals.

However, organizations have leapt at the chance to help their fellow Houstonians, and a number of resources have appeared to provide aid to startups, from advice and resources to grants. Continue reading.
Last year, California-based Nuro, a self-driving car tech company, launched three pilots in Houston. Courtesy of Nuro

California self-driving vehicle startup has all eyes on Houston — here's why

On a roll

Houston — with its sprawl and winding roads broken up across various neighborhoods — is particularly challenging when it comes to self-driving car navigation. And that's exactly why Nuro, a California-based tech startup that's raised over $1 billion in funding, decided to focus on the Bayou City for its autonomous vehicle delivery pilot programs.

"Houston is our first full-scale operations city," Sola Lawal, product operations manager in Houston, tells InnovationMap. "All eyes at Nuro are focused on Houston."

Last year alone, Nuro launched three pilots in six of Houston's ZIP codes from Bellaire to the Heights. The first of which was a partnership with Kroger in March, followed by the announcement of autonomous pizza delivery from Domino's in June. Last month, Nuro announced its latest delivery partner was Walmart.

Lawal explains Houston's appeal to Nuro in a few ways, but the challenging landscape is key. Nuro cars are learning from the narrow, tree-laden streets of West University or the pedestrian-heavy, ditch-lined paths in the Heights.

"There's a ton for us to learn, but it's a great microcosm of the United States in a number of different ways," he says.

In addition to its diversity within its street types, Houston, named the most diverse city in the country, represents an ideal customer base, says Lawal, a Houston native himself. Houstonians are open minded about new experiences.

"If you think and look across Houston, the average commute is over 60 minutes for people to get back and forth," Lawal tells InnovationMap. "As we surveyed across major cities we were interested in, Houston stood out as a place where customers said they don't want go to the grocery store if they don't have to or get in their cars again to pick up their pizza."

The third reason Houston was a great market for Nuro is the amount of regulatory support the state of Texas has — Gov. Greg Abbott announced the launch of the Texas Connected and Autonomous Vehicle task force a year ago — as well as the support at the city level.

"It's been a welcoming environment from the mayor's office down for us to be here," Lawal says.

Since entering the Houston market, Nuro's local operations have grown to over 100 employees. The company still has software operations out of California, and some work being done in Arizona, but the Houston is the largest — and growing as the company seeks new partnerships with more stores with a goal of eliminating errands once and for all.

"The way that we think about this is that this new technology and our mission of accelerating robotics for everyday life, is we will bring the people what they want," Lawal says when asked about what types of stores Nuro is looking to partner with.

Eventually, Lawal says, the plan would be to have every errand be delivery optimized with Nuro technology — from big-box stores like Walmart to your local florist.

"Our goal is to have a platform that retailers can connect to in order to provide easy and inexpensive delivery," he says.

Currently, Nuro's technology is still in learning mode. Nuro's fleet of Prius cars with staff onboard are driving up and down Houston streets mapping and taking notes on a daily basis. The company also has bots, called the R2 fleet, that are designed to be unmanned.

These bots are smaller than normal cars and are completely electric. Rather than being designed to protect passengers inside like traditional automobiles, the R2s are designed to be safe for people outside the vehicle.

"It's a new way of thinking about transportation and what our vehicles can and should do," Lawal says.

2020 is the year of these R2 bots, and some areas can expect to see them in action — specifically focused on Domino's pizza delivery — in just a matter of weeks.

From a supercomputer making its debut in West Houston to a behind-the-scenes look at Amazon's artificial intelligence-enabled fulfillment center, these were Houston's top stories in tech. Natalie Harms/InnovationMap

Here were Houston's top 5 tech innovation stories of 2019

2019 in review

Editor's note: Houston had some big stories in technology this year, from a peek inside Amazon's artificial intelligence-enabled Houston facility and the opening of a new supercomputer to space-focused Houston startups and the future of virtual reality.

Massive data center officially opens just west of Houston

Matthew Lamont is managing director at DownUnder GeoSolutions' which just opened its new, powerful data center west of Houston. Courtesy of DUG

DownUnder GeoSolutions has officially opened its new data centre in Skybox Houston in Katy, Texas. It's being billed as one of the most powerful supercomputers on earth.

The center, which houses DUG's geophysical cloud service, DUG McCloud, celebrated its grand opening on Thursday, May 16. The company's data hall has 15 megawatts of power and resides in a building designed to withstand hurricane-force winds up to 190 mph.

A second, identical hall is already planned to be built out later this year. Together, the two machines will have a capacity of 650 petaflop, which is a measurement of computing speed that's equal to one thousand million million floating-point operations per second. Continue reading.

5 startups keeping Houston known as the Space City

Houston celebrated 50 years since the Apollo moon landing on July 20. Here are some startups that are going to be a part of the next 50 years of space tech in Houston. Photo via NASA.gov

This month, for the most part, has been looking back on the history Houston has as the Space City in honor of the 50th anniversary of the moon landing on July 20. While it's great to recognize the men and women who made this city the major player in space exploration that it is, there are still entrepreneurs today with space applications and experience that represent the future of the Space City. Continue reading.

How Amazon's Houston fulfillment center uses AI technology and robotics to move millions of products

From robotics to artificial intelligence, here's how Amazon gets its products to Houstonians in record time. Photo by Natalie Harms/InnovationMap

Last summer, Amazon opened the doors to its North Houston distribution center — one of the company's 50 centers worldwide that uses automation and robotics to fulfill online orders.

The Pinto Business Park facility has millions of products in inventory across four floors. Products that are 25 pounds or less (nothing heavier is stocked at this location) pass through 20 miles of conveyor belts, 1,500 employees, and hundreds of robots.

The center also has daily tours open to the public. We recently visited to see for ourselves the process a product goes through at this Houston plant. From stowing to shipping, here's how packages go from your shopping cart to your front porch. Continue reading.

Developments in virtual reality technology are changing the workforce, say Houston experts

The solution to Houston's workforce problem might be right in front of our eyes. Getty Images

Everyone's job has training associated with it — from surgeons to construction crane operators — and there's a growing market need for faster, more thorough training of our workforce.

"The best way to learn how to do something, is to just get out and do it," says Eric Liga, co-founder of HoustonVR. "But there are a lot of reasons why you can't do that in certain types of training."

Augmented and virtual reality training programs are on the rise, and Liga cites safety, cost, and unpredictable work environments as some of these most obvious reasons reasons to pivot to training employees through extended reality. This type of training also provides portability and has proven higher retention, Liga says in his keynote speech at Station Houston's AR/VR discuss on April 25.

"You get a much higher retention rate when you actually go out and do something — physically going through the motions — than you do sitting in a classroom or reading a book," he says. Continue reading.

Recently renovated Downtown Houston office space snags leases from 2 tech companies

Main&Co's office space is now 100 percent leased. Courtesy of Main&Co

Two tech-focused companies moved into a newly developed office space in downtown Houston at the intersection of Main Street and Commerce Street. One company relocated its Houston office, and the other company has expanded to the city for the first time.

Oil and gas AI-enabled analytics platform, Ruths.ai relocated its downtown office to Main&Co, located at 114 Main St. The company has 8,457 square feet of office space in the recently renovated historic building.

Meanwhile, global robotics process automation company UiPath has expanded to build a Houston team. The computer software company is based in New York, but has a presence in 18 countries. The company's office has 5,187 square feet of Main&Co's office space. Continue reading.
INK, a digital writing tool, allows writers to see how their content would perform on search engines in real time. Photo courtesy of INK

Houston tech company launches digital product to take the guesswork out of SEO

Meet INK

A Houston company wants to arm content creators and writers with the tools to perfect search engine optimization, and they want to provide these tools for free.

INK, a downloadable writing tool and web app, was created by the brains behind Edgy Labs, a tech company that has been working on dissecting how Google and search engines operate. Edgy's founders — Alexander De Ridder, Michael Umansky, and Gary Haymann — created the content site as a lab to test out their SEO theories and best practices.

"INK is the byproduct of everything we've learned at Edgy Labs that we productized," says Umansky, who serves as CEO. "We think we are on the cusp of leading what we are calling the content performance optimization revolution."

Umansky says that of the 4 million pieces of content created online daily, 94 percent of content gets little to no traffic on Google. And a big reason for content failing is because the writer doesn't fully understand how SEO works — and search engines are always evolving their algorithms.

Despite this huge SEO problem, there weren't any one-stop-shop tools available already.

"What we came to understand was that there's a ton of SEO and CMS products and analytics products, but what there wasn't was a really good way to help writers — who are really the ground zero for where content is created — bridge the gap to understanding what SEO is all about," Umansky says.

INK edgy labs INK allows writers to see in real time how their content would fare on Google. Photo courtesy of INK

The writing tool allows the user to create content right in the app, and as the writer composes, he or she gets real-time feedback on the content. INK will compare the content to potential competitors' content and analyze and score how it expects the published material to perform. All the while, INK has a customizable interface for users. There are light and dark modes, and even features for writers with dyslexia or color blindness.

Umansky says his team has big plans for growing INK and even introducing more tools and products, and INK's evolution will continue as search engines continue updates and algorithm edits.

"As Google changes, we change with it," Umansky says. "I think last year Google changed something like 3,500 times. It's constant."

He also sees INK being able to provide a headline optimization component, as well as tools for tracking engagement. While perfecting SEO is the first step, Umansky says he also wants to provide products that help optimize writing content for a conversion perspective that would be good for landing pages and digital ads.

INK launched online in early October and was ranked as the product of the week on Product Hunt. For now, the app is completely free to download. Umansky does think the first paid version will be live in the first quarter of 2020.

Ultimately, Umansky says, writers shouldn't also have to be SEO specialists — that's INK's team's job. The product they created will allow for easy content management system integration — it already has an extension in WordPress.

"We envision a world where the content creators can control their own search destiny," Umansky says. "What we want to do is focus on empowering those writers to really take the power of search back into their own hands without having to be SEO experts."
California-based Sidecar Health has rolled out its health insurance tech services in Texas. Images via sidecarhealth.com

Health insurance tech startup taps Texas for its launch due to its large uninsured population

in control

The health insurance situation in Texas is anemic.

Last year, 17.7 percent of Texans lacked health insurance, according to newly released data from the U.S. Census Bureau. That's the highest rate of uninsured residents among all of the states.

The problem is even more acute in the Houston metro area. In 2018, nearly 1 in 5 residents of the region (18.6 percent) had no health insurance, the Census Bureau says. That's the highest rate of uninsured residents among the country's 25 most populous metro areas.

If you do the math, that translates into more than 5 million residents of Texas, including more than 1.3 million in the Houston area, who have no health-insurance safety net. A startup called Sidecar Health is setting out to reduce those numbers.

Texas recently became the first market for Sidecar Health's insurance plans, which it promotes as being "personalized" and "affordable." By the end of this year, the El Segundo, California-based company hopes to enroll at least 5,000 Texans.

Just as with subscription services like Netflix and Amazon Prime, a consumer can sign up for or cancel their Sidecar Health plan at any time. A member can lock in their Sidecar Health rate for three years.

Technically, Sidecar Health isn't an insurance company. Rather, it manages the insurance plans that it sells.

"Sidecar Health is different from traditional insurance in that we pay a fixed amount for any medically necessary service or prescription drug that you buy," the company explains on its website. "That means if your provider charges more than that fixed amount, you pay the difference. And if your provider charges less, you keep the difference."

Through Sidecar Health, a consumer can visit any healthcare provider, healthcare facility, or pharmacy they choose, as long as self-paying patients with credit cards or debit cards are accepted. This setup allows "complete transparency and control over healthcare costs," says Patrick Quigley, the startup's CEO.

"We make this possible by enabling our members to pay for care when they get it using the Sidecar Health payment card. Because doctors get paid immediately, they offer huge discounts. On average, it is 33 percent or more cheaper than what they charge big insurance companies," Quigley tells InnovationMap. "And because our members are doing the buying by swiping the card, they know what things cost. So you get true transparency and affordability — the way health insurance should be."

Through the Sidecar Health app, a member can see how much healthcare providers in their area charge, enabling them to compare prices.

"Our approach results in a truly affordable option for the millions of people left behind by the traditional model — those who don't qualify for a government subsidy but can't afford the cost of traditional plans," Quigley says in a release.

Sidecar Health is operating throughout Texas without any employees or offices in the state. The company sells its product directly through its website. On the website, consumers can educate themselves on available insurance plans before signing up online. Its Texas insurance plans are underwritten by Eatontown, New Jersey-based United States Fire Insurance Co., part of insurance conglomerate Crum & Forster.

Since its founding in 2018, Sidecar Health has raised $18 million in funding, led by San Francisco-based GreatPoint Ventures and Los Angeles-based Morpheus Ventures.

The startup's offering "is a great example of taking an otherwise complex process and making it simple, which is why Sidecar Health is such a game changer in health insurance," says Joseph Miller, managing partner of Morpheus Ventures.
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Chevron's Houston-based venture arm launches $300M fund focusing on low-carbon tech

show me the money

Chevron Corp.'s investment arm has launched a $300 million fund that will focus on low-carbon technology.

Chevron Technology Ventures LLC's Future Energy Fund II builds on the success of the first Future Energy Fund, which kicked off in 2018 and invested in more than 10 companies specializing in niches like carbon capture, emerging mobility, and energy storage. The initial fund contained $100 million.

"The new fund will focus on innovation likely to play a critical role in the future energy system in industrial decarbonization, emerging mobility, energy decentralization, and the growing circular carbon economy," Houston-based Chevron Technology Ventures says in a February 25 release.

Future Energy Fund II is the eighth venture fund created by Chevron Technology Ventures since its establishment in 1999. In 2019, the investment arm started a $90 million fund to invest in startups that can help accelerate the oil and gas business of San Ramon, California-based Chevron.

Chevron Technology Ventures' portfolio for low-carbon technology comprises a dozen companies: Blue Planet, Carbon Clean, Carbon Engineering, ChargePoint, Eavor, Infinitum Electric, Natron Energy, Spear Power Systems, Svante, Voyage, Vutility, and Zap Energy.

Only one of the companies in the low-carbon portfolio is based in Texas — Infinitum Electric, located in Round Rock. However, Chevron Technology Ventures is active in the Houston entrepreneurial ecosystem as a participant in the Rice Alliance for Technology and Entrepreneurship, Greentown Labs, The Cannon, and The Ion. Chevron's investment arm was the first tenant at The Ion.

In an August 2020 interview with InnovationMap, Barbara Burger, president of Chevron Technology Ventures, said the investment arm places a priority on helping advance entrepreneurship in Houston. "It is our home court," she said.

Burger said that for Houston to succeed in energy innovation, companies, government agencies, investment firms, and universities must rally around the city.

"We're doing a lot of things right — almost in spite of the world being crazy. … I think constancy of purpose is important," she said. "Despite the headwinds from COVID and despite the headwinds that industries are facing, we need to stay committed to that."

Burger noted that innovation "is not a straight path."

"We've got to plant a bunch of these seeds and see how they grow — we need to water them every day, and then I think we'll have a beautiful garden," she said.

Now's the time to find innovation opportunities in a trustless world, says this Houston expert

guest column

Hidden beneath all the recent events in the technology work, stock market, political landscape, and most of the social problems we see today lies one underlying trend. A trend so powerful that it's causing disruption in nearly every institution out there, and changing the business landscape faster than anyone can keep up.

Trust is gone. I mean completely gone.

At this point, the examples of this are too numerous to list but let's look at the past several months in the United States. In that short period, we saw an incredibly contentious election process, big tech disable the primary communication of a world leader, a mass exodus do decentralized messaging, an explosion in the defi industry and crypto, and a once promising vaccine process somehow not be effective despite being the primary conversation topic for everyone.

And this was all before a bunch of social media users treated the world's greatest stock market like a game, and far after we saw a country divided into two by racial movements, and we have yet to even get to things such as the Russian hacks.

We're left with an absolute mess of a situation where every social contract seems to be broken and the default response to any sort of central authority is being reevaluated. Without doubt we'll eventually figure out some great long-term answers, but at the speed at which the business world works today, it's going to be messy.

Luckily, mess creates opportunity and within all this disruption lies many golden nuggets of opportunity. The last twelve months was likely a watershed moment in key areas and as innovators, and business people — and it's our job to find them. It's what we signed up for and, for many of us, why we do what we do.

If there was ever a time to invest heavily in innovative technologies, today is it. Most of the time businesses are very resistant to change. Their default answer is always "no," and this puts innovators in a constant search of early adopters. But today, we see a different landscape. Businesses of all sizes and industries have been tossed around like a toy ship in an ocean. They do not know which way is up and business as usual seems like an old campfire story. Everyone, everywhere is looking for creative ideas to improve their business, and creative ideas is at the heart of true entrepreneurship and innovation.

Within this disruption also lies a few other key support pillars that should benefit all innovative minded individuals.

  • Despite terrible economic conditions, those invested in tech over the past year have done incredibly well. These individuals should be primed to reinvest their profits into bigger wins.
  • The workforce is truly global, and people are scrambling. The ideas of location being an advantage to hiring is truly disappearing. This means talent acquisition costs are falling through the floor and availability through the ceiling.
  • Consumers and businesses alike have been introduced to new technology so the legwork of explaining things such as defi and blockchain is much easier. It's also easy to find numerous use cases for anything involving proximity, health, privacy, and security.
  • The new administration will be eager to find wins, and invest money in different technologies than the previous. No matter what you think politically about this strategy, the reality is that areas such as healthcare, education, and will offer innovation opportunities. Even regulation itself, which we are likely to see increased, can be a great playground for innovation.

Twenty years ago, the way that business was done is unrecognizable in some industries. Many of the successful business today did not even exist then. Technology has a tendency to change things exponentially so imagine what the next ten years will look like. What are we not seeing today that will be the new business as usual?

The future is ours to create

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Cody Caillet is the founder at Gulf Coast Solutions, a Houston-based technology firm with speed-to-value approach in delivering business technology to impact top-line and bottom-line numbers for a business.

These 3 Houston researchers are revolutionizing health science innovation

research roundup

Research, perhaps now more than ever, is crucial to expanding and growing innovation in Houston — and it's happening across the city right under our noses.

In InnovationMap's latest roundup of research news, a couple local scientists are honored by awards while another duo of specialists tackle a new project.

University of Houston professor recognized with award

Mehmet Orman of UH has been selected to receive an award for his research on persister cells. Photo via UH.edu

Mehmet Orman, assistant professor of chemical and biomolecular engineering at the University of Houston Cullen College of Engineering has been honored with a Faculty Early Career Development Award from the National Science Foundation. The award comes with a $500,000 grant to study persister cells — cells that go dormant and then become tolerant to extraordinary levels of antibiotics.

"Nearly all bacterial cultures contain a small population of persister cells," says Orman in a news release. "Persisters are thought to be responsible for recurring chronic infections such as those of the urinary tract and for creating drug-resistant mutants."

Previously, Orman developed the first methods to directly measure the metabolism of persister cells. He also developed cell sorting strategies to segregate persisters from highly heterogeneous bacterial cell populations, and, according to the release, he will be using his methods in the NSF research project.

Houston researchers collaborate on oral cancer innovation

Dr. Simon Young of UTHealth and Jeffrey Hartgerink of Rice University are working on a new use for an innovative gel they developed. Photo via Rice.edu

Two Houston researchers — chemist and bioengineer Jeffrey Hartgerink at Rice University and Dr. Simon Young at the University of Texas Health Science Center at Houston — have again teamed up to advance their previous development of a sophisticated hydrogel called STINGel. This time, they are using it to destroy oral cancer tumors.

SynerGel combines a pair of antitumor agents into a gel that can be injected directly into tumors. Once there, the gel controls the release of its cargo to not only trigger cells' immune response but also to remove other suppressive immune cells from the tumor's microenvironment. The duo reported on the technology in the American Chemical Society journal ACS Biomaterials Science & Engineering.

SynerGel, combines a pair of antitumor agents into a gel that can be injected directly into tumors, where they not only control the release of the drugs but also remove suppressive immune cells from the tumor's microenvironment.

"We are really excited about this new material," Hartgerink says in a news release. "SynerGel is formulated from a specially synthesized peptide which itself acts as an enzyme inhibitor, but it also assembles into a nanofibrous gel that can entrap and release other drugs in a controlled fashion.

In 2018, the pair published research on the use of a multidomain peptide gel — the original STINGel — to deliver ADU-S100, an immunotherapy drug from a class of "stimulator of interferon gene (STING) agonists."

The research is supported by the Oral and Maxillofacial Surgery Foundation, the National Institutes of Health, the Welch Foundation, the National Science Foundation and the Mexican National Council for Science and Technology.

Texas Heart Institute researcher honored by national organization

Dr. James Martin of Texas Heart Institute has been named a senior member of the National Academy of Inventors. Photo courtesy of THI

The National Academy of Inventors have named Houston-based Texas Heart Institute's Dr. James Martin, director of the Cardiomyocyte Renewal Lab, a senior member.

Martin is an internationally recognized developmental and regenerative biologist and his research is focused on understanding how signaling pathways are related to development and tissue regeneration.

"Dr. Martin has long been a steward of scientific advancement and has proven to be a tremendous asset to the Texas Heart Institute and to its Cardiomyocyte Renewal Lab through his efforts to translate fundamental biological discoveries in cardiac development and disease into novel treatment strategies for cardiac regeneration," says Dr. Darren Woodside, vice president for research at THI, in a news release. "Everyone at the Texas Heart Institute is thrilled for Dr. Martin, whose induction into the NAI as a Senior Member is well-deserved."

Martin has authored over 170 peer-reviewed papers in top journals he holds nine U.S. patents and applications, including one provisional application, all of which have been licensed to Yap Therapeutics, a company he co-founded.

The full list of incoming NAI Senior Members, which includes three professionals from the University of Houston, is available on the NAI website.

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