Houston Technology Center founder dies, leaves legacy of innovation

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Paul Frison, the founder of the Houston Technology Center, has died. Photo via dignitymemorial.com

The Houston innovation ecosystem is mourning the loss of one of its early leaders, Paul Frison, who died on September 5. He was 87.

A long-time Houston businessman, Frison founded the Houston Technology Center in 1999 and served as its CEO and president. The organization evolved into Houston Exponential several years ago. Frison remained active within Houston innovation until 2020.

“Paul Frison was a visionary and energetic leader who always presented a positive outlook on what the Houston technology entrepreneurship community could become," Brad Burke, associate vice president for industry and new ventures at Rice University's Office of Innovation, remembers. "He was one of the pioneers in the community who established the Houston Technology Center as one of the early leaders of the Houston ecosystem. I admired how he helped launch the ecosystem and created the platform for many others to build upon.”

Prior to HTC, he served in various executive roles at American Hospital Supply, LifeMark, ComputerCraft, and LifeCell, spending the last 50 of his years in Houston. Born in Glendale, California, he served in the Unites States Coast Guard.

Blair Garrou, co-founder and managing director of Mercury Fund, says Frison was his first boss and mentor in the tech and entrepreneurship sector.

“When people look back to how the Houston tech community was founded, it starts with Paul Frison," Garrou says. "Paul had run multiple companies and I was lucky to have him as CEO when I worked for him at the Houston Technology Center. He quickly became a mentor, and over time, a good friend and confidant. I have Paul to thank for launching my career in tech and venture capital.

"My favorite quote of Paul’s was, 'Do not confuse effort with results,'” Garrou continues. "Despite his results-driven work ethic – which was legendary — Paul was also deeply-rooted in family and faith, and has been a role model for me over my entire professional life.”

He is preceded in death by his wife, Barbara, and his grandson, Christian David Elders. He is survived by his daughters Maryanne Elders and Jill Cortez and their families, including grandchildren Matthew Elders, Laney Elders, Max Cortez, Jake Cortez, and Sofie Cortez.

A celebration of life will be held for Frison on September 16 at 1 pm at Second Baptist Church, with a reception following in the Deacon’s Parlor. More details are available online. In lieu of flowers, Frison's wishes were for for donations to Second Baptist Church to be made in his honor.

Angela Wilkins joins the Houston Innovators Podcast to discuss the intersection of data and health care. Photo courtesy

Houston data scientist joins medical device startup amid AI evolution in the sector

HOUSTON INNOVATORS PODCAST EPISODE 241

When most people hear about Houston startup Starling Medical, they might think about how much potential the medical device company has in the field of urinalysis diagnostics. But that's not quite where Angela Wilkins's head went.

Wilkins explains on the Houston Innovators Podcast that when she met the company's co-founders, Hannah McKenney and Drew Hendricks, she recognized them as very promising startup leaders taking action on a real health care problem. Starling's device can collect urine and run diagnostics right from a patient's toilet.

"It was one of those things where I just thought, 'They're going to get a bunch of data soon,'" Wilkins says. "The opportunity is just there, and I was really excited to come on and build their AI platform and the way they are going to look at data."

For about a year, Wilkins supported the startup as an adviser. Now, she's working more hands on as chief data officer as the company grows.



Wilkins, who serves as a mentor and adviser for several startups, has a 20-year career in Houston across all sides of the innovation equation, working first at Baylor College of Medicine before co-founding Mercury Data Science — now OmniScience. Most recently she served as executive director of the Ken Kennedy Institute at Rice University.

This variety in her resume makes her super connective — a benefit to all the startups she works with, she explains. The decision to transition to a startup team means she gets to work hands on in building a technology — while bringing in her experience from other institutions.

"I think I've really learned how to partner with those institutions," she says on the show. "I've really learned how to make those bridges, and that's a big challenge that startups face."

"When we talk about the Houston innovation ecosystem, it's something we should be doing better at because we have so many startups and so many places that would like to use better technology to solve problems," she continues.

Wilkins has data and artificial intelligence on the mind in everything she does, and she even serves on a committee at the state level to learn and provide feedback on how Texas should be regulating AI.

"At the end of the day, the mission is to put together a report and strategy on how we think Texas should think about AI," she explains. "It's beyond just using an algorithm, they need infrastructure."

Colorado is the first state to pass legislation surrounding AI, and Wilkins says all eyes are on how execution of that new law will go.

"We should have technology that can be double checked to make sure we're applying it in a way that's fair across all demographics. It's obvious that we should do that — it's just very hard," she says.

Houston's ranking on this global report improved 14 spots between now and last year. Photo via Getty Images

Houston tech ecosystem ranks as No. 5 in the world for emerging startup hubs

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As a startup hub, Houston is movin’ on up.

In a new report from Startup Genome and the Global Entrepreneurship Network, Houston ranks fifth among the world’s top 100 emerging ecosystems for startups. Last year, the groups’ report put Houston at No. 19 in the same category.

Ahead of Houston on the list of the top emerging ecosystems for startups are first-ranked Detroit; second-ranked Hong Kong; third-ranked Dublin, Ireland; and fourth-ranked Minneapolis.

Further bolstering Houston’s status as a rising startup hub, Bayou City ranks third among the top North American challengers to traditional startup anchors like Silicon Valley, Boston, and Seattle. Joining Houston on the challengers’ list are first-ranked Detroit; second-ranked Minneapolis; third-ranked Research Triangle, North Carolina; and fifth-ranked Pittsburgh.

A recent report from Houston Exponential, which was recently acquired, emphasizes Houston’s position as the third fastest-growing tech ecosystem in the U.S. for early-stage startups. Houston sits behind Miami (No. 2) and Bridgeport-Stamford-Norwalk, Connecticut (No. 1).

Houston startups at all stages raised $2.34 billion in 2021, setting a record for the region’s annual VC haul, the HX report says. Of that total, early-stage startups collected $618.9 million in 46 deals.

Health and information technology startups dominate the VC landscape in Houston, with each accounting for 30 percent of VC deals in 2021, according to the HX report.

Elsewhere in Texas, Austin ranks 25th among the world’s top 100 ecosystems for startups, while Dallas ties for 31st place, according to the Startup Genome and Global Entrepreneurship Network report. San Antonio is wedged into the 91-to-100 range in the ranking of the world’s top 100 ecosystems.

“The importance and dispersal of tech startups have amplified the influence — for both good and ill — of geopolitics,” the report notes. “Where once the sector was sufficiently small to avoid the kind of pressures experienced by large industries such as energy and travel, those garage-spawned entrepreneurs have grown into a major economic force. Keeping their heads down is no longer an option.”

Houston's density is possibly its biggest challenge when it comes to developing its innovation ecosystem, says a Houston expert. Getty Images

Houston needs to overcome its lack of density to continue to develop as an innovation ecosystem, says expert

Guest column

From the front porch of Houston, Texas, we solve some of humanity's hardest challenges. We're the ones who put humans on the Moon and rovers on Mars, go subsea in search of hydrocarbons, and are discovering a cure for cancer. We solve complex challenges, because of a characteristic seemingly embedded deep within our DNA — we are all explorers of the unknown.

Today, a new challenge is rallying our attention, inspiring us to push the boundaries yet again. And, that's the hard challenge of population density. Houston is fourth in population in the country, and yet 89th in the number of people per unit of area.

Why is this an issue, one might ask? Houston, like many other cities around the world, is racing to become a hub for innovation, a critical catalyst fueling the next generation of growth and economic prosperity. And, density is a key component of innovation — it brings divergent mindsets together to look at challenges from multiple perspectives and creates an environment that brings big bold ideas to life.

However, the nature of our geography has created silos that are not easily broken down and separates us by industries, communities, interests, mindsets, and access to transportation, among other things.

But, let's not underestimate our true spirit — and our ability to explore the unexpected, push the boundaries and tackle the challenges the world throws at us.

If I learned anything from living here my entire life, Houston has grit, imagination, and motivation and knows what it means to be a trailblazer. Houston is the most diverse city in the United States. Our culinary landscape is constantly pushing the boundaries of creativity and imagination. Local graffiti and modern art installations are reshaping the visual identity of our community. Our sports and performing arts "rockstars" consistently deliver real-time experiential immersion.

We need to recognize and embrace how these colors of Houston connect us all regardless of our geographic silos and push innovation forward. Said another way, we have all the colors; we just need to converge and paint the canvas together.

True to our nature, some of our Houstonian friends have begun chipping away at this challenge already. Central Houston is attracting world-renowned incubators and accelerators like MassChallenge and Gener8tor — and this scene alone is ever-expanding. The Cannon, The Ion, Impact Hub, Launchpad, Headquarters, and other players are creating environments that bring people together and meet the needs of an ever-evolving workforce through experiential community. We even have a dedicated publication for all things innovation — Innovation Map — sharing resources across our vast city and ensuring no great story is left untold.

Our rich diversity means we have access to human beings from a multitude of backgrounds, which in itself is a force to be reckoned with. By interacting with a variety of human beings, we become more empathetic, understanding, and celebratory of new ideas. This is fundamental to continuous innovation — how we interact and approach challenges, engage in new experiences, and become an inspirational leader in life and work. So, break down the silos and access the diversity of thinking that's already outside the door.

At the same time, the challenge of density must be tackled not only physically but also digitally. By converging the physical and digital ecosystem through a neural network, we can intelligently connect the activity with centralized access to start-ups, corporations, nonprofits, free-lancers, incubators, accelerators, maker-spaces, academia, local influencers, and public partners. Digitally bridging all of us can make one of the largest and most spread-out cities in the U.S. feel like a small Texas town with big ideas and an ever-stronger dimension of inclusivity.

So, join the movement, strike up a conversation, grab your metaphorical spray paint and converge with all the vibrant colors of Houston as we energize the future of humanity, navigate to Mars and back safely, and annihilate the existence of cancer.

As Steve Jobs said: "The people who are crazy enough to think that they can change the world, are the ones who do." Are we ready?

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Brad Rossacci is creative director at Accenture's Innovation Hub in Houston.

Thomas Rubenak is senior principal of Accenture Ventures. Courtesy of Accenture

New Accenture exec aims to put Houston's innovation ecosystem on the map

Featured Innovator

In most industries, there's a disconnect between startups and major corporations. The startups may have solutions for the big companies, but the two entities might not know how to connect with each other. That's something Accenture hopes to help with.

The company created Accenture Ventures to help connect the dots between emerging technology and big business. As the program has expanded, Thomas Rubenak was selected to serve the Southwest region as senior principal.

With a long career of working in tech, research and design, and startups, Rubenak hopes to use his experience to help grow Houston's blossoming innovation ecosystem.

"It takes a village. It's not just the amazing accelerators we have throughout the region," Rubenak says. "If you look at the Cannon, Houston Exponential, MassChallenge, and all of the ecosystem — it takes all of us together to prop up a thriving economy. That's what we're doing. We're changing not just the face of Houston but really impacting the startups as well as the clients we serve."

Rubenak spoke with InnovationMap to discuss the role Accenture Ventures plays in the ecosystem and how he sees innovation in Houston growing.

InnovationMap: You're new to your role, but you've worked with tech and startups for years. Tell me a little bit about your career to date. 

Thomas Rubenak: I come most recently from EY. I did a few assignments there, primarily working with the EY and Microsoft alliance. I was also a go-to-market lead for deep technical accounting for IPOs and other regulatory compliance issues. I worked a lot with the Entrepreneur of the Year program. Before that, I spent most of my career in tech research with Gartner and Forrester. This space is all about brilliant minds that really focus on helping the world understand what's next in emerging technology. I worked pretty extensively with venture capital, private equity and venture banks.

IM: While you’ve worked on projects across the country, you’ve been based in Houston, so you’ve been able to see the city transform, right?

TR: In my career, I've been really fortunate enough to align with amazing people in the market. Several years ago, we started a community just in Houston to bring entrepreneurs, angel investors, and some VC together. It was a nonprofit, grassroots effort called TeXchange; I just wanted to help entrepreneurs connect to sources of capital.

IM: How did Accenture Ventures get its start and what does it aim to do?

TR: Accenture realized four years ago that in order to stay competitive, it needed to tap the best of the best in the startup world. The only way to do that is to dedicate resources and people to that task, and that's how we started Ventures. As a recent joiner, my role is primarily the lead for the Southwest to bring the best of the startup ecosystem into our clients to help them solve their most pressing problems. And it's not just about problems, but also about opportunities.

It's a win-win-win. The client gets the benefit of having the best of the best and the startups get amazing exposure to companies they might not have been able to get in front of. And, Accenture is happy because it gets to serve the client.

Accenture works in multiple sectors, including resources (oil and gas), chemicals, mining — so for obvious reasons, the Southwest is a big sector for us — but, we also tap the health and public safety sectors.

As we look to design these arrangements with these startups and we find that there is a compelling need to invest in them, we'll become a minority investor. If that startup then has a M&A play that makes sense to everyone, we'll look into that as well.

IM: How do Accenture Ventures and the Innovation Hub work together?

TR: I am part of the hub, and I also serve the broader team.

What we bring to the table is amazing talent to data scientists to designers — many different resources — and we work with our clients to figure out what they want to solve or if there's a play in the market they are interested in. We can pull the best from Accenture and from the startup ecosystem to design solutions.

IM: What’s the most challenging thing about solving clients’ goals?

TR: It's not a challenge so to speak, but it's something I have to be mindful of, and that is always keeping the client's interest at hand, so recognizing and realizing that they have short- and long-term goals that they want to achieve.

IM: What's it like working with companies on the startup side?

TR: We seek specific types of startups. In order for us to be really effective, we keep a pulse on the market. Our focus is on companies that have gotten their source of funding, they've gone through their first round, companies that have great management who have been in industry or served big companies, and companies that are disruptors, innovators, or have something really compelling to bring to us. The challenge is that there are so many of them. There are so many great startup companies doing amazing things. But, as many startups as there are, there's just as many client issues.

IM: In your opinion, what challenges does the Houston innovation ecosystem still have to overcome?

TR: It's no secret that the economic engine of venture capital is in the east and west coasts. We have a lot of great VCs here, but it's about how do we keep our startups here. That's an issue that everyone talks about. But we also have seen a lot of startups move to Houston from other places. But, from the financial aspect of it, I think we could always use more of that. I personally don't think there will ever be another Silicon Valley, but we'll be something different. We'll be ourself. But, we do need those sources of capital in place. But something I want to mention is the diversity and the universities in Houston — we have a lot going for us.

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Portions of this interview have been edited.

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Rice biotech accelerator appoints 2 leading researchers to team

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The Rice Biotech Launch Pad, which is focused on expediting the translation of Rice University’s health and medical technology discoveries into cures, has named Amanda Nash and Kelsey L. Swingle to its leadership team.

Both are assistant professors in Rice’s Department of Bioengineering and will bring “valuable perspective” to the Houston-based accelerator, according to Rice. 

“Their deep understanding of both the scientific rigor required for successful innovation and the commercial strategies necessary to bring these technologies to market will be invaluable as we continue to build our portfolio of lifesaving medical technologies,” Omid Veiseh, faculty director of the Launch Pad, said in a news release.

Amanda Nash

Nash leads a research program focused on developing cell communication technologies to treat cancer, autoimmune diseases and aging. She previously trained as a management consultant at McKinsey & Co., where she specialized in business development, portfolio strategy and operational excellence for pharmaceutical and medtech companies. She earned her doctorate in bioengineering from Rice and helped develop implantable cytokine factories for the treatment of ovarian cancer. She holds a bachelor’s degree in biomedical engineering from the University of Houston.

“Returning to Rice represents a full-circle moment in my career, from conducting my doctoral research here to gaining strategic insights at McKinsey and now bringing that combined perspective back to advance Houston’s biotech ecosystem,” Nash said in the release. “The Launch Pad represents exactly the kind of translational bridge our industry needs. I look forward to helping researchers navigate the complex path from discovery to commercialization.”

Kelsey L. Swingle

Swingle’s research focuses on engineering lipid-based nanoparticle technologies for drug delivery to reproductive tissues, which includes the placenta. She completed her doctorate in bioengineering at the University of Pennsylvania, where she developed novel mRNA lipid nanoparticles for the treatment of preeclampsia. She received her bachelor’s degree in biomedical engineering from Case Western Reserve University and is a National Science Foundation Graduate Research Fellow.

“What draws me to the Rice Biotech Launch Pad is its commitment to addressing the most pressing unmet medical needs,” Swingle added in the release. “My research in women’s health has shown me how innovation at the intersection of biomaterials and medicine can tackle challenges that have been overlooked for far too long. I am thrilled to join a team that shares this vision of designing cutting-edge technologies to create meaningful impact for underserved patient populations.”

The Rice Biotech Launch Pad opened in 2023. It held the official launch and lab opening of RBL LLC, a biotech venture creation studio in May. Read more here.

University of Houston archaeologists make history with Mayan tomb discovery

History in the Making

Two University of Houston archaeologists have made scientific history with the discovery of a Mayan king's tomb in Belize.

The UH team led by husband and wife scientists Arlen F. Chase and Diane Z. Chase made the discovery at Caracol, the largest Mayan archeological site in Belize, which is situated about 25 miles south of Xunantunich and the town of San Ignacio. Together with Belize's Institute of Archeology, as well as support from the Geraldine and Emory Ford Foundation and the KHR Family Fund, they uncovered the tomb of Caracol's founder, King Te K’ab Chaak. Their work used airborne light detection and ranging technology to uncover previously hidden roadways and structures that have been reclaimed by the jungle.

The tomb was found at the base of a royal family shrine. The king, who ascended the throne in 331 AD, lived to an advanced enough age that he no longer had teeth. His tomb held a collection of 11 pottery vessels, carved bone tubes, jadeite jewelry, a mosaic jadeite mask, Pacific spondylus shells, and various other perishable items. Pottery vessels found in the chamber depict a Maya ruler wielding a spear as he receives offerings from supplicants represented as deities; the figure of Ek Chuah, the Maya god of traders, surrounded by offerings; and bound captives, a motif also seen in two related burials. Additionally, two vessels had lids adorned with modeled handles shaped like coatimundi (pisote) heads. The coatimundi, known as tz’uutz’ in Maya, was later adopted by subsequent rulers of Caracol as part of their names.

 Diane Chase archaeologist in Mayan tomb Diane Z. Chase in the Mayan tomb. Photo courtesy of University of Houston

During the Classical Period, Caracol was one of the main hubs of the Mayan Lowlands and covered an area bigger than that of present-day Belize City. Populations survived in the area for at least 1,000 years before the city was abandoned sometime around 900 AD. The royal dynasty established by Te K’ab Chaak continued at Caracol for over 460 years.

The find is also significant because this was roughly when the Mexican city of Teotihuacan made contact with Caracol, leading to a long relationship of trade and cultural exchange. Cremation sites found in Caracol contain items that would have come from Teotihuacan, showing the relationship between the two distant cities.

"Both central Mexico and the Maya area were clearly aware of each other’s ritual practices, as reflected in the Caracol cremation," said Arlen F. Chase, professor and chair of Comparative Cultural Studies at the University of Houston.

“The connections between the two regions were undertaken by the highest levels of society, suggesting that initial kings at various Maya cities — such as Te K’ab Chaak at Caracol — were engaged in formal diplomatic relationships with Teotihuacan.”

The Chases will present their findings at a conference on Maya–Teotihuacan interaction hosted by the Maya Working Group at the Santa Fe Institute in New Mexico in August 2025.

 UH professors Chase make Mayan Discovery UH archaeologists Arlen F. Chase and Diane Z. Chase Photo courtesy of University of Houston

 

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This story originally appeared on CultureMap.com.

Houston palliative care company integrates with Epic platforms

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Patients and medical teams using MyChart and other Epic Systems' software will now be able to access Houston-based Koda Health's AI-enhanced end-of-life planning platform.

The Houston-based palliative care company, which was born out of the TMC's Biodesign Fellowship, has integrated its advance care planning platform with Epic, one of the most widely used electronic health record (EHR) systems in the U.S., according to a news release.

Epic estimates that more than 325 million patients have a current electronic record in its systems.

“This is a significant milestone for our mission to make advance care planning scalable, meaningful, and seamless,” Tatiana Fofanova, CEO and co-founder of Koda Health, said in the release. “By integrating into systems already used by care teams, we help eliminate friction and ensure that care delivery honors what patients truly want—especially during serious illness and at the end of life.”

The partnership will streamline processes for both patients and clinicians. Users will be able to drop advance care plans directly into the Epic charts, which will be accessible through MyChart for patients and proxies and through Epic Hyperspace/Hyperdrive for care teams. Doctors can also initiate and manage advance care plans through a simple Epic order for patients.

According to Koda Health, its platform saves an average of $10,000 to $15,000 per patient. Roughly 85 percent of users complete advance care plan documents when using the platform, which is four times the national average.

“We developed Koda to give providers the time, training, and tools to guide these critical conversations," Dr. Desh Mohan, co-founder and chief medical officer at Koda Health, added in the statement. "Our integration now makes it possible to operationalize ACP at scale—aligned with value-based care goals and clinical reality.”

The company announced a partnership with Dallas-based Guidehealth, which integrates into primary care workflows and allows providers to identify high-risk patients, coordinate care and reduce administrative burden. Guidehealth works with more than 500,000 patients

Koda Health was founded in 2020 and closed an oversubscribed seed round for an undisclosed amount last year, with investments from AARP, Memorial Hermann Health System and the Texas Medical Center Venture Fund. The company also added Kidney Action Planning to its suite of services in 2024.

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