Among this week's top stories is a feature on a Houston-based startup aiming to be the Uber or Lyft of personal trainers. Courtesy of Kanthaka

Editor's note: Houston saw big shake ups at some major innovation institutions this week, which made for some trending stories. And, per usual, readers enjoyed learning about local entrepreneurs fighting the good fight with their organizations.

Station Houston announces its transition into becoming a nonprofit

Station Houston's stakeholders voted in favor of the organization transitioning to a nonprofit. Station Houston/Facebook

Houston's startup scene just got a little more accessible. Station Houston's stakeholders voted to transition the organization to nonprofit status from the C-corp status it currently holds. The status change is effective January 1, 2019, for the acceleration hub, which is based in downtown Houston. The news was announced to its members in an email sent on December 13. Read the full story here.

Houston entrepreneur creates a network to link up with other blockchain professionals

The Houston Blockchain Alliance aims to connect and educate tech professionals in town. Getty Images

Houstonians traveling around the country might covet other cities for their mountain scapes, beaches, or more mild summers, but Mahesh Sashital envied the fact that other major cities had developed networks and organizations focused on connecting and educating tech professionals. Houston, it seems, was late to the party.

So, he decided to make his own blockchain-focused organization, and a few months ago, he launched the Houston Blockchain Alliance. Read the full story here.

3 Houston energy innovators to know this week

These energy startup leaders are the reason Houston will keep its "energy capital of the world" title. Courtesy images

Houston's known as the energy capital of the world, but it won't stay that way if the city as a whole doesn't work toward innovation. These three professionals started their own companies to improve efficiency and promote ingenuity in their fields. From drones and AI to quicker pipeline data access, this week's three innovators to know are the future of the energy industry. Read the full story here.

TMC Innovation Institute leader leaves the organization

Erik Halvorsen has reportedly left his position at the TMC Innovation Institute. Courtesy of TMC

Erik Halvorsen, director of the Texas Medical Center's Innovation Institute, has left his position, according to multiple reports.

TMC's medical device innovation team lead, Lance Black, was named as the interim replacement for Halvorsen, according to Xconomy. Black has been with TMC for almost two years. Read the full story here.

Get on-demand personal training from Houston-based app

Houston-based Kanthaka is the Uber or Lyft of personal training, and has recently expanded into the Austin market. Courtesy of Kanthaka

As a busy lawyer who traveled heavily for work, Sylvia Kampshoff found her workouts were often overlooked as she went from city to city, a casualty of long hours and a busy schedule. And, even though she did have a membership to a national gym with privileges at any of its locations, she hated the feeling of always being sold something and disliked that both the trainers and managers she worked with took very little interest in her personal needs and fitness goals.

She wanted something that allowed her to exercise with someone on her own schedule, and with people who valued customer service. That's how the idea for Kanthaka was born. Read the full story here.


The Houston Blockchain Alliance aims to connect and educate tech professionals in town. Getty Images

Houston entrepreneur creates a network to link up with other blockchain professionals

New kids on the block

Houstonians traveling around the country might covet other cities for their mountain scapes, beaches, or more mild summers, but Mahesh Sashital envied the fact that other major cities had developed networks and organizations focused on connecting and educating tech professionals. Houston, it seems, was late to the party.

So, he decided to make his own blockchain-focused organization, and a few months ago, he launched the Houston Blockchain Alliance.

Sashital, who is the co-founder of Smarterum, a blockchain news site, works from home and says — every once and a while — he needs some "adult talk time" with his fellow tech professionals.

"I thought that I'd start the Houston Blockchain Alliance so that someone like me, who's already in the industry, can find other people working in the industry," he says. "And for other people interested in blockchain can learn more and get up to speed with the technology."

The Houston Blockchain Alliance's goals are two part: to connect and to educate. The group plans to have an event in February, Sashital says, as well as a citywide blockchain conference in the third or fourth quarters of 2019. Sashital also wants to inform those interested on blockchain news and development by providing educational resources and opportunities.

"We plan on having workshops where people can talk about all sorts of aspects of blockchain — there's so much to talk about," he says. "We can have workshops on legal, accounting, technical, business strategy, and more."

Sashital, who's been a developer for the better part of his life, has a bigger, personal goal for the alliance too. He's worked and lived in Houston for 12 years and he says he's noticed that Houston hasn't yet claimed a reputation for being a tech city. It gets beaten out by cities like Austin, which just was announced to be the home of the new Apple campus. But a decade or so ago, Austin didn't have a tech reputation either. The city positioned itself to be that, and now it's Houston's turn, he says.

"We have a whole bunch of tech workers in Houston — but they are all fragmented across the city. We want to change that perception that Houston's not the place to go if you want to do tech work," Sashital says.

"Hopefully the Houston Blockchain Alliance is a small step in that direction."

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Rice researchers score $45M from NIH for cancer-fighting tech

freshly funded

A research funding agency has deployed capital into a team at Rice University that's working to develop a technology that could cut cancer-related deaths in half.

Rice researchers received $45 million from the National Institutes of Health's Advanced Research Projects Agency for Health, or ARPA-H, to scale up development of a sense-and-respond implant technology. Rice bioengineer Omid Veiseh leads the team developing the technology as principal investigator.

“Instead of tethering patients to hospital beds, IV bags and external monitors, we’ll use a minimally invasive procedure to implant a small device that continuously monitors their cancer and adjusts their immunotherapy dose in real time,” he says in a news release. “This kind of ‘closed-loop therapy’ has been used for managing diabetes, where you have a glucose monitor that continuously talks to an insulin pump. But for cancer immunotherapy, it’s revolutionary.”

Joining Veiseh on the 19-person research project named THOR, which stands for “targeted hybrid oncotherapeutic regulation,” is Amir Jazaeri, co-PI and professor of gynecologic oncology at the University of Texas MD Anderson Cancer Center. The device they are developing is called HAMMR, or hybrid advanced molecular manufacturing regulator.

“Cancer cells are continually evolving and adapting to therapy. However, currently available diagnostic tools, including radiologic tests, blood assays and biopsies, provide very infrequent and limited snapshots of this dynamic process," Jazaeri adds. "As a result, today’s therapies treat cancer as if it were a static disease. We believe THOR could transform the status quo by providing real-time data from the tumor environment that can in turn guide more effective and tumor-informed novel therapies.”

With a national team of engineers, physicians, and experts across synthetic biology, materials science, immunology, oncology, and more, the team will receive its funding through the Rice Biotech Launch Pad, a newly launched initiative led by Veiseh that exists to help life-saving medical innovation scale quickly.

"Rice is proud to be the recipient of the second major funding award from the ARPA-H, a new funding agency established last year to support research that catalyzes health breakthroughs," Rice President Reginald DesRoches says. "The research Rice bioengineer Omid Veiseh is doing in leading this team is truly groundbreaking and could potentially save hundreds of thousands of lives each year. This is the type of research that makes a significant impact on the world.”

The initial focus of the technology will be on ovarian cancer, and this funding agreement includes a first-phase clinical trial of HAMMR for the treatment of recurrent ovarian cancer that's expected to take place in the fourth year of THOR’s multi-year project.

“The technology is broadly applicable for peritoneal cancers that affect the pancreas, liver, lungs and other organs,” Veiseh says. “The first clinical trial will focus on refractory recurrent ovarian cancer, and the benefit of that is that we have an ongoing trial for ovarian cancer with our encapsulated cytokine ‘drug factory’ technology. We'll be able to build on that experience. We have already demonstrated a unique model to go from concept to clinical trial within five years, and HAMMR is the next iteration of that approach.”

TMC again expands global impact with new Netherlands partnership

breaking news

The Texas Medical Center may be based in Houston, but the organization has again grown its global impact.

Since 2016, TMC’s BioBridges have worked with 88 startup companies. Those include strategic alliances with four other countries. Australia, the United Kingdom, Denmark and Ireland are all among TMC’s BioBridges partners. As of today, add the Netherlands to that list.

On September 27, TMC president and CEO, William F. McKeon, and Carmen van Vilsteren, chair of Health~Holland, Top Sector Life Sciences & Health (LSH), signed an agreement in Rotterdam. The TMC Netherlands BioBridge Memorandum of Understanding codifies the innovative goals of the partnership. Essentially, the BioBridge program provides a means for entrepreneurs, researchers, clinicians and industry partners from other countries to access the US market, as well as TMC experts.

“The TMC Netherlands BioBridge represents an unparalleled opportunity for collaboration and growth,” Ashley McPhail, chief external affairs & administration officer at Texas Medical Center said in a press release. “The Netherlands has solidified its position as a global leader in the field of life sciences and health, with a thriving ecosystem of research institutions, innovative companies, and highly skilled professionals. This strategic partnership will bring positive benefits to patients, clinicians and industry partners on a global scale.”

This lifeline for international healthcare companies makes expansion into the United States far smoother. The Global Innovators Launch Pad allows for startup founders to take part in a 10-week residency at the TMC Innovation Factory that will teach them about foundational infrastructure, clinical evidence and funding in the US.

“Since Texas is an important hub for innovation in the MedTech and digital health sectors, the collaboration with Texas Medical Center creates opportunities for Dutch companies looking to expand their international reach. Vice versa, it gives companies in Texas access to the vibrant Dutch Life Sciences & Health sector,” said van Vilsteren.

That exchange includes members of the TMC gaining the opportunity to participate in the Health~Holland Visitors Programme (HVP), “Shaping the Healthcare of the Future.”

The annual event invites high-level representatives from the private sector, NGOs, knowledge institutions, healthcare providers and different tiers of government to share their expertise.

It's the fifth partnership of its kind for TMC, with the last one being with Ireland, announced last year. TMC's other global initiatives include accelerators with Denmark and the United Kingdom, both announced earlier this year.

Houston startup founders prepare to scale globally following Shark Tank success

HOUSTON INNOVATORS PODCAST EPISODE 205

While Milkify's founders — husband and wife team Pedro Silva and Berkley Luck — secured partners on a popular business pitch and investment show, the entire experience almost didn't happen.

Silva and Luck, who got her PhD in molecular and biomedical s at Baylor College of Medicine, founded the company to provide breast milk freeze drying as a service to Houston-area families. Now, Milkify has customers across the country, but the duo didn't know if going through the process would be worth the investment and publicity, or if it would just be a distraction.

"The competitor in me wanted to be the first breast milk company to go on the show and to tell our story to the world — to show the world what my wife came up with that we thought was so great," Silva says on the Houston Innovators Podcast. "It was probably the scariest 45 minutes of my life."

But the sharks bit. Milkify's episode aired in April, and two investors — Gwyneth Paltrow and Lori Greiner — agreed to a $400,000 convertible note for 20 percent equity in the company. Paltrow even said on the show that she would have used the service when she was breastfeeding.

"It was empowering," Luck says of getting to wear her white coat on TV and share the story of how she came up with the idea of Milkify. "It was important to me when we went on the show to express that this had a scientific basis, that we didn't start this lightly, and that we've made huge strides in doing this in the absolute safest way possible."

Silva says they can't talk about some of the details of the show or the deal, but since then, Milkify has reached new customers, received additional investment interest, grown its team, and built out its plan to scale, the founders shared on the podcast. The team also shares its big-picture scale plans, which include tapping international partners to potentially take Milkify's tech global.

"Our vision is for every family to have access to breast milk formula, but instead of re-creating breast milk in a lab, we're doing it with mom's own milk," Silva says, mentioning a partnership with a breast milk bank that will convert its operation from freezing to freeze drying donated milk. "We're also working with groups in the UK and Australia to launch similar services using our patented technology."

"By the end of the year, we hope to see some announcements with those partnerships across the globe."

From the beginning, the importance of Milkify's team has been on supporting working parents to give them the best way to care for their families, Silva says. And for Luck — who says she's proud of the integrity Milkify has at its core despite competitors offering lower-quality and, in some cases, dangerous alternatives — she sees a lot of research benefits for the company.

"It's amazing to be at this leading edge, not just of innovation but of research, and to be able to still put out meaningful advances as an industry partner, not just as an academic," Luck says, adding that she hopes to be able to continue to contribute to the ongoing research into breast milk.

Luck and Silva share more about their Shark Tank experience, their co-founder strengths, and the future of Milkify on the podcast. Listen to the interview here — or wherever you stream your podcasts — and subscribe for weekly episodes.