10+ can't-miss Houston business and innovation events for April

Where to be

From enlightening talks to networking opportunities, here's where you need to be in April. Getty Images

Happy Q2, everyone. With 2019 already a quarter of the way through, it's a bit overwhelming to prioritize what networking and thought talks to attend. We've rounded up a list of over 10 (and growing) events for you to consider adding to your calendar.

If you know of innovation-focused events for this month or next, email me at natalie@innovationmap.com with the details and subscribe to our daily newsletter that sends fresh stories straight to your inboxes every morning.

April 4 — FIRMSPACE Houston Grand Opening Celebration

A national high-end workspace brand has opened its latest location in Houston. Check out the space and network with potential coworkers.

Details: The event is from 7 to 10 pm on Thursday, April 4, at FIRMSPACE Houston (2200 Post Oak Boulevard). Learn more.

April 4 — Accelerator Info Session and Panel

Join the Social Enterprise Alliance for an info session on BBVA Momentum's accelerator program followed by a panel discussion led by Grace Rodriguez, CEO of Impact Hub Houston.

Details: The event is from 11:30 am to 1 pm on Thursday, April 4, at Station Houston (1301 Fannin, suite 2440). Learn more.

April 4-6 — Rice Business Plan Competition

This weekend, 42 teams will be competing for over $1.5 million in awards at the 19th annual Rice Business Plan Competition. Learn more about the awards and teams here.

Details: The three-day challenge takes place in a few different buildings on Rice University Campus. Learn more.

April 5 — ChIPs Texas' Houston Innovation Ecosystem

Gina Luna of Houston Exponential and Tom Luby of the TMC Innovation Institute will take the stage for a panel moderated by Payal Patel of Station Houston. It's the first ChIPs event in Houston. ChIPs is a nonprofit organization that advances and connects women in technology, law, and policy.

Details: The event is from 11:30 am to 1:30 pm on Friday, April 5, at TMC Innovation Institute (2450 Holcombe Blvd, Suite X). Learn more.

April 10 — MassChallenge Texas' Houston Launch Party

In case you missed it, MassChallenge Texas has a new Houston program and it's officially launching this month. Network with the international program, potential applicants, and other members of the Houston innovation ecosystem.

Details: The event is from 6 to 8 pm on Wednesday, April 10, at Four Seasons Houston (1300 Lamar St.). Learn more.

April 11 — 2019 Future of Leadership Luncheon

The annual event honors leadership and celebrates the important role of philanthropy in the Houston community. Tickets start at $250 for the luncheon that features a conversation between Darren Walker, president of the Ford Foundation, and Laura Arnold, co-chair of Arnold Ventures, on the future of philanthropy.

Details: The event is from noon to 1:30 pm on Thursday, April 11, at the Hilton Americas (1600 Lamar Street). Learn more here.

April 11 — Startup Pains: What I Wish I Knew

This monthly series hosted by the University of Houston lets you learn from someone else's mistakes and successes. This month's speaker is Jason Eriksen, Ph.D.UH associate professor of pharmacy, and founder of Alzeca Biosciences and Teomics LLC.

Details: The event is from 4 to 5 pm on Thursday, April 11, at the UH Technology Bridge (Innovation Center, building 4, floor 2, 5000 Gulf Fwy). Learn more here.Learn more here.

April 11 — B2B Startup Pitch Party

Cannon Ventures is hosting another night of pitches. This event is focused on all things B2B and will feature some B2B startups looking for early stage funding in Houston.

Details: The event is from 6:30 to 9 pm on Thursday, April 11, at The Cannon (1336 Brittmoore Road). Learn more.

April 12 — The Agile Shift Conference

Join industry professionals to network and talk the unification of Agile and DevOps to build and deliver better teams and software.

Details: The event is from 8 am to 5 pm on Friday, April 12, at the Hyatt Regency Houston (1200 Louisiana St.). Learn more.

April 18 — Lemonade Day at Station Houston

Join Station Houston for what is likely going to be the cutest pitch competition you'll ever see. Ten teams made up of future entrepreneurs will pitch their ideas for a lemonade stand.

Details: The event is from 5:30 to 7:30 pm on Thursday, April 18, at Station Houston (1301 Fannin Street, suite 2440). Learn more.

April 18 — Rice Alumni | Entrepreneurs & Innovators, Houston Launch

A Rice University organization has a new name, and they are ready to celebrate it. Meet the new Rice Alumni | Entrepreneurs & Innovators network, or RA|EI, and discuss what you want out of the organization.

Details: The event is from 5:30 to 7:30 pm on Thursday, April 18, at Pitch 25 (2120 Walker Street). Learn more.

April 23 — Houston Female Founder Roundtable: How to Get Ahead in Entrepreneurship with Alice

A panel of entrepreneurial women will share their stories, challenges, successes, and tips.

Details: The event is from 11 am to 1 pm on Tuesday, April 23, at The Cannon (1336 Brittmoore Rd). Learn more.

April 25 — EO Talks Houston

Think TED Talks but from Houston entrepreneurs. The goal is to share success stories and inspire other entrepreneurs in town.

Details: The event is from 7:30 to 10:30 am on Thursday, April 25, at Houston Baptist University, Linda & Archie Dunham Theater (7502 Fondren Road). Learn more.

April 25 — 7th Annual City of Houston Investor Conference

The City of Houston is gathering professionals to talk money for a full day of presentations by local government CFOs and an update on the region's economy.

Details: The event is from 8 am to 5 pm on Thursday, April 25, at Hilton Americas-Houston (1600 Lamar Street). Learn more.

April 25 — Enterprise XR: How AR/VR is Preparing Modern Workers

Immersive technology is shifting the paradigm of corporate training, and you and your company need to learn about it. The event has a keynote speaker and networking before and after.

Details: The event is from 6:30 to 8 pm on Thursday, April 25, at Station Houston (1301 Fannin St., suite 2440). Learn more.

April 26 — Data Science and You: Ethics in Data Science

Visiting professor Lawrence Hunter, director of the Computational Bioscience Program and of the Center for Computational Pharmacology at the University of Colorado School of Medicine, talks advances in data science and what you need to know.

Details: The event is from 3 to 5 pm on Friday, April 26, at the University of Houston Student Center (4455 University Drive).Learn more here.

April 26 — SPE Pitch Perfect

Join the Society of Professional Engineers' GCS Innovate! Committee for an event that will help you perfect your business plan.

Details: The event is from 9 am to 2 pm on Friday, April 26, at the Newpark Drilling Fluids (21920 Merchants Way). Learn more here.

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Houston cleantech, space startups named to World Economic Forum cohort

top honor

Two Houston-based startups have been selected to join the World Economic Forum's Technology Pioneers community.

The two-year program aims to help mission-driven, early-stage start-ups scale their innovations through multi-stakeholder initiatives, co-creating partnerships and other gatherings for community members. One-hundred startups are selected each year from around the globe, this year hailing from 23 countries and working in AI, energy, space, biotech markets and more.

Cleantech startup Vaulted Deep was one of 11 energy and climate companies to be named to the cohort. Julia Reichelstein and Omar Abou-Sayed founded the company in 2023. Its technology injects excess organic waste underground to remove carbon dioxide from the atmosphere.

Last year, Vaulted Deep inked a 12-year deal with Microsoft to remove up to 4.9 million metric tons of carbon dioxide from the environment.

The startup has earned several accolades in recent years, including a No. 3 spot on Fast Company’s list of the World’s Most Innovative Companies of 2026. It was also recently named to market intelligence and advisory firm Cleantech Group's annual Global Cleantech 100 list for a second year in a row.

"Waste management is one of the world's great invisible infrastructure systems ... The need for new infrastructure is growing as disposal challenges become more complex and regulations evolve. Vaulted is building the first new disposal pathway for organic waste in decades by putting it deep underground, permanently," the company shared in a LinkedIn post. "This year, we're joining the World Economic Forum's 2026 Tech Pioneers alongside innovators working on the many interconnected challenges shaping our future."

Houston-based Venus Aerospace was also selected to join the cohort, along with six other spacetech companies. The company was founded in 2020 by Sassie and Andrew Duggleby.

The startup specializes in next-generation rocket engine propulsion as a cleaner alternative to traditional combustion engines. The company's rotating detonation rocket engine (RDRE) burns fuel more efficiently and completed a successful high-thrust test flight last year. Venus says it’s the only company in the world that makes a flight-proven, high-thrust RDRE with a “clear path to scaled production.”

"Frontier technologies matter most when they expand what people, industries, and nations can do," Sassie Duggleby, co-founder and CEO of Venus, said in a news release. "For Venus, RDRE does not just represent a more efficient engine. It is a foundation for faster movement, more capable space systems, and new forms of connectivity across the planet. Being named a Technology Pioneer validates the potential of this technology to help shape a future where distance is less limiting."

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston Methodist receives record $110M gift, names future tower

historic gift

Houston Methodist has received the largest gift in the health system's history to establish new funds for neurological, neuroscience, and women’s health research and treatment.

The $110 million gift comes from Houston-based The Brockman Medical Research Foundation, which supports education and research in the science, medicine and healthcare fields. In response, Houston Methodist announced that it will name its forthcoming 26-story hospital facility the Brockman Centennial Tower.

The tower’s entrance will be named the Anna Margaret Bellows Centennial Hall to honor Anna Margaret Bellows, a young camper who died during the Camp Mystic flooding last summer.

“This extraordinary gift accelerates discovery and transforms how care is delivered,” Dr. Marc Boom, president and CEO of Houston Methodist, said in a news release. “We are grateful to The Brockman Medical Research Foundation for its incredible generosity and vision that will help change the lives of generations of patients. Naming Centennial Tower in recognition of this gift reflects the scale of this commitment and its impact on the future of neuroscience, neurological care and women’s health.”

The gift will be divided into two parts:

$100 million will go toward creating an innovation fund within the Houston Methodist Academic Institute and the Houston Methodist Neurological Institute
$10 million will be devoted to Houston Methodist's Department of Obstetrics and Gynecology

“This tremendous gift will accelerate translational research that broadens our understanding of neurological and other diseases,” Dr. Jenny Chang, president and CEO of the Houston Methodist Academic Institute, added in the release. “It will allow us to leverage state-of-the-art platforms to detect, diagnose and deliver therapeutics, keeping patient care at the center of our mission.”

The Brockman Centennial Tower is expected to open next year in the Texas Medical Center. Spanning more than 1 million square feet, it will house 400 patient beds, an expanded emergency department, new operating rooms and a rooftop garden. It will be connected to Houston Methodist's flagship Paula and Joseph C. “Rusty” Walter III Tower, which opened in 2018. The Centennial Tower was estimated to cost $1.4 billion when announced in 2022.

In addition to the news of the Brockman gift, Houston Methodist also announced this month that it has launched the Houston Methodist Center for Cell and Gene Therapy and tapped an internationally recognized scientist as its leader.

The new center is focused on discovering and developing innovative and cost-effective therapies for a variety of congenital and acquired diseases, including cancer, HIV and cardiovascular disease.

Dr. Malcolm Brenner has been named as the center's inaugural leader and will assume the role starting in October. He will work alongside scientists and support staff from Baylor College of Medicine and Texas Children's Hospital.

Brenner is a professor of pediatrics, medicine, molecular and human genetics and translational biology at Baylor College of Medicine. He is known for making early advances in using bone marrow transplantation as a form of cell therapy and in engineered immune-cell treatments for cancer and infections, according to a release from Houston Methodist.

“Malcolm Brenner is a pioneer in the field of cell and gene therapy and is uniquely qualified to lead Houston Methodist’s research efforts in this field,” Chang added. “His vision and leadership will play a pivotal role in advancing our work in this space.”

Report: Houston reclaims top 10 ranking among America's best cities

Houston has made a triumphant return to America's 10 best cities for 2026, certifying the city is a cornerstone of the country's growth and economic prosperity.

Houston ranks No. 9 nationwide in the annual "America's Best Cities" report from Canada-based real estate and tourism marketing firm Resonance Consultancy. Each year, the report ranks the relative qualities of livability, cultural "lovability," and economic prosperity in 393 American cities with metropolitan populations of 500,000 or more.

Dallas surpassed H-Town as the No. 8 best city in America, and the Lone Star State boasts a strong presence among the top 25. Austin and San Antonio, respectively, were named the 11th and 24th best American cities this year.

Previously, Houston was dubbed the 13th best American city in 2025, down from its No. 10 ranking in the 2024 report.

Rather than profiling each individual city like in past reports, the 2026 edition focuses on regional and state prosperity. Texas' economic dominance is second only to Florida's, and the state's growth is solidified by the Dallas-Houston-Austin "triangle," where each metro has its own distinct economic identity, but when combined "form one of the most formidable regional economies in the world."

"In our 2026 survey, Dallas ranks third nationally as the place Americans believe offers the best job opportunities, Austin fifth, and Houston seventh," the report's author wrote. "That concentration of perceived economic opportunity in a single state is unmatched, and the GDP data confirms it isn’t just perception."

After being named one of the best places to start a business or a career earlier in 2026, Houston has continued to punch above its weight with its success in tourism, education , and housing growth .

Overall, the report found a correlation between a city's population growth and its latest ranking, with bigger cities appearing higher up on the list. The top three best American cities — New York, Los Angeles, and Chicago — are coincidentally the three largest metros, while Dallas and Houston are the fourth and fifth largest but appear eighth and ninth on the list.

"Scale compounds at the large city level — more people generate more economic activity, more cultural infrastructure, more employer presence, which attracts more people," the report said.

The top 10 best cities in America for 2026 are:

No. 1 – New York
No. 2 – Los Angeles
No. 3 – Chicago
No. 4 – Miami
No. 5 – San Francisco
No. 6 – Seattle
No. 7 – Las Vegas
No. 8 – Dallas
No. 9 – Houston
No. 10 – Boston

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