3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Steve Latham of DonateStock, Arianne Dowdell of Houston Methodist, and Howard Berman of Coya Therapeutics. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from fintech to health care DEI — recently making headlines in Houston innovation.

Steve Latham, co-founder and CEO of DonateStock

Houstonian and serial entrepreneur plans to scale nonprofit fintech toolThe sky's the limit for DonateStock, Co-Founder and CEO Steve Latham says. Photo courtesy of DonateStock

For the third time in his career, serial entrepreneur Steve Latham recession activity, so he feels confident he knows the playbook of how to handle what's on the horizon. For his latest venture, Donate Stock, a tech platform that simplifies stock donation for both the donor and the beneficiary, he's focused on weathering whatever storm is incoming.

"We've raised more money to extend our runway, and we're keeping a super tight lid on expenses because your cash is your oxygen," he says. "There are companies going out of business in our industry right now that had really promising businesses but just spent too much money before they could get to the revenue phase."

He shares the background story on DonateStock and his own career on last week's Houston Innovators Podcast episode. Read more and stream the episode.

Arianne Dowdell, vice president and chief diversity, equity and inclusion officer at Houston Methodist

Arianne Dowdell spoke with InnovationMap about Houston Methodist's DEI initiatives — and how they will help develop the hospital of the future. Photo courtesy of Houston Methodist

Innovation and equity are two things they have to go together — and Houston Methodist knows that. Which is why Arianne Dowdell serves as vice president and chief diversity, equity and inclusion officer at Houston Methodist. Under her leadership, the health care provider is putting the patients at the forefront of the hospital system's priorities through its DEI initiatives.

In an interview with InnovationMap, Dowdell shares more about these ongoing initiatives and her role, as well as the importance of DEI in innovative health care.

"It doesn't matter if you're down here in the medical center or out in Baytown," she says. "The innovation and what we're thinking about and the technologies and the way that we communicate with our patients, all that is part of innovation, which helps our DEI initiatives become more successful in everything that we're doing." Read more.

Howard Berman, CEO of Coya Therapeutics

A Houston biotech startup focused on developing therapeutics for neurodegenerative and autoimmune diseases has closed its IPO. Photo courtesy of Coya

A clinical-stage biotech company based in Houston has announced the closing of its $15.25 million IPO.

Coya Therapeutics, now trading under the ticker COYA, announced this week that its IPO — previously disclosed in December — has closed its initial public offering of 3,050,000 shares of its common stock and accompanying warrants to purchase up to 1,525,000 shares of common stock, per a news release. Howard Berman, CEO of Coya Therapeutics, has lead the company since February of 2021. Read more.

A Houston biotech startup focused on developing therapeutics for neurodegenerative and autoimmune diseases has closed its IPO. Photo via Getty Images

Houston biotech company closes IPO in $15.25M deal

new ticker

A clinical-stage biotech company based in Houston has announced the closing of its $15.25 million IPO.

The company is developing proprietary therapies to enhance the function of regulatory T cells to target systemic inflammation and neuroinflammation.

According to the company, the net proceeds from the offering — which was estimated to be at around $13.2 million, per a release — will go toward advancing its programs in preclinical studies into clinical trials — as well as to advance its discovery and candidate selection stage programs and other scaling purposes.

In 2021, Coya Therapeutics announced that it had merged with Nicoya Health Inc. and raised $10 million in its series A. The round was led by Florida-based Allele Capital Partners LLC. Howard Berman, founder and board of directors for imaware, was named the CEO of Coya, as well as a member of the company's board of directors, alongside the merger and series A announcement.

Coya's therapeutics uses innovative work from Dr. Stanley H. Appel, co-director of Houston Methodist Neurological Institute and Chair of the Stanley H. Appel Department of Neurology at Houston Methodist Hospital. The researcher has created a way to "isolate dysfunctional Tregs from a patient, convert them to a highly functional and neuroprotective condition, and expand these cells into the billions for intravenous reinfusion back to the patient," says Berman in a 2022 news release. This revolutionary work overcomes previous limitations in the field.

"Patients with neurodegenerative diseases are in desperate need of transformative therapeutic options; harnessing the neuroprotective effects of Treg cell therapy shows great potential in unlocking a new treatment paradigm and may enable us to revolutionize care for patients with devastating neurodegenerative diseases," Appel said last February. "We have successfully demonstrated, in a phase 1 trial, the safety and tolerability of autologous infusions of expanded Tregs in ALS patients, with the potential of slowing or halting disease progression. Ongoing studies provide a transformative framework for advanced clinical trials in ALS and other neurodegenerative disorders."

These fast-growing companies have new personnel announcements to share. Photos courtesy

3 Houston tech startups name new leadership members

SHORT STORIES

Three Houston startups have new hires they're excited about. From new board members to C-level execs, here's who's moving and shaking in Houston innovation.

Software company hires new product exec

Photo courtesy of Cart.com

Cart.com, an end-to-end e-commerce services provider, announced Michael Svatek as the company's first chief product officer. Formerly, Svatek served as chief product and strategy officer at Bazaarvoice and then co-founded and served as the CEO and head of product at Rivet Works, a cloud software platform.

"Michael's deep expertise across the e-commerce technology value chain coupled with his experience in M&A, strategic alliances, and entrepreneurship are one-of-a-kind in this industry, and a testament to our growth and trajectory at Cart.com," says Omair Tariq, Cart.com co-founder and CEO, in a news release. "We are so pleased to welcome Michael, a proven leader with an innate understanding of the Cart.com mission to unify and streamline the fragmented e-commerce value chain for brands of any size."

Earlier this year, Cart.com raised a $25 million series A funding round and emerged from stealth mode.

Fast-growing e-commerce startup lawyers up

Photo courtesy of GoExpedi

Houston-based GoExpedi, another tech company disrupting e-commerce, once again expanded its executive board, naming Julie Gremillion as general counsel. She has more than 10 years of experience in working with energy companies, and will lead the company's legal strategy, managing compliance and risk throughout the organization, and more.

"We are thrilled to have found Julie, one of the most experienced, savvy and well-rounded legal counsels in the industry," says Tim Neal, GoExpedi CEO, in a news release. "Her legal background in the energy space is beyond reproach. As we enter this next critical phase of growth, Julie's combined commercial and legal expertise will provide us with a platform for long-term and sustainable success."

GoExpedi also recently fundraised a $25 million round last fall.

Recently acquired therapeutics company adds board member

Photo via aiche.org

Clinical-stage biotechnology company, Coya Therapeutics Inc. has appointed Ann Lee., senior vice president of Cell Therapy Development and Operations at Bristol Myers Squibb, to the company's board of directors.

"Dr. Lee is one of the leading cell therapy technical development, supply chain and manufacturing executives in the biopharmaceutical industry," says Howard Berman, Coya CEO, says in a release. "At Coya, we are revolutionizing cell therapy manufacturing and supply chain management via proprietary cryopreservation to overcome prior limitations of Treg cell therapies. Dr. Lee's expertise will be instrumental as we advance in the clinic and build out manufacturing partnerships."

The company, which focuses on creating therapeutics for neurodegenerative and autoimmune diseases, announced earlier this year that it has completed a merger with Nicoya Health Inc. and raised $10 million in its series A.

A biotech startup focused on developing therapeutics for neurodegenerative and autoimmune diseases has some big news to share. Photo via Getty Images

Houston biotech startup announces merger and $10M series A

getting ahead

A Houston company has emerged from stealth mode to announce a merger and a round of financing.

Coya Therapeutics, a clinical-stage biotech startup that focuses on creating therapeutics for neurodegenerative and autoimmune diseases, announced that it has completed a merger with Nicoya Health Inc. and raised $10 million in its series A. The round was led by Florida-based Allele Capital Partners LLC. Howard Berman, founder and board of directors for imaware, has been named CEO of Coya, as well as a member of the company's board of directors.

Coya's therapeutics uses innovative work from Dr. Stanley H. Appel, co-director of Houston Methodist Neurological Institute and Chair of the Stanley H. Appel Department of Neurology at Houston Methodist Hospital. The researcher has created a way to "isolate dysfunctional Tregs from a patient, convert them to a highly functional and neuroprotective condition, and expand these cells into the billions for intravenous reinfusion back to the patient," says Berman in a news release. This revolutionary work overcomes previous limitations in the field.

"I'm excited to have the opportunity to lead Coya at such an exciting and pivotal phase of growth," Berman says. "Through our sponsored research program in conjunction with Dr. Appel, we look forward to continuing advancement of this promising work and translating this work into a meaningful therapy for patients."

The company's fresh funds will be used to continue work on the company's lead therapeutic program, ALS001, an autologous, expanded Treg cell therapy for amyotrophic lateral sclerosis (ALS) patients , as well as to introduce clinical pipeline candidates targeting Parkinson's disease, Alzheimer's disease, frontal temporal dementia, and more, according to the release.

"Patients with neurodegenerative diseases are in desperate need of transformative therapeutic options; harnessing the neuro-protective effects of Treg cell therapy shows great potential in unlocking a new treatment paradigm and may enable us to revolutionize care for patients with devastating neurodegenerative diseases," says Appel. "We have successfully demonstrated, in a phase 1 trial, the safety and tolerability of autologous infusions of expanded Tregs in ALS patients, with the potential of slowing or halting disease progression. Ongoing studies provide a transformative framework for advanced clinical trials in ALS and other neurodegenerative disorders."

Tribal Capital Markets LLC acted as sole placement agent for the offering, according to the release, and Allele Capital Partners — through Tribal Capital Markets — was responsible for sourcing, investing and executing the $10 million offering.

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Following Silicon Valley Bank collapse, banking diversification is key for Houston founders

SVB shake up

Last week, Houston founder Emily Cisek was in between meetings with customers and potential investors in Austin while she was in town for SXSW. She was aware of the uncertainty with Silicon Valley Bank, but the significance of what was happening didn't hit her until she got into an Uber on Friday only to find that her payment was declined.

“Being positive in nature as I am, and with the close relationship that I have with SVB and how they’ve truly been a partner, I just thought, ‘OK, they’re going to figure it out. I trust in them,'” Cisek says.

Like many startup founders, Cisek, the CEO of The Postage, a Houston-based tech platform that enables digital legacy planning tools, is a Silicon Valley Bank customer. Within a few hours, she rallied her board and team to figure out what they needed to do, including making plans for payroll. She juggled all this while attending her meetings and SXSW events — which, coincidentally, were mostly related to the banking and fintech industries.

Sandy Guitar had a similar weekend of uncertainty. As managing director of HX Venture Fund, a fund of funds that deploys capital to venture capital firms around the country and connects them to the Houston innovation ecosystem, her first concern was to evaluate the effect on HXVF's network. In this case, that meant the fund's limited partners, its portfolio of venture firms, and, by extension, the firms' portfolios of startup companies.

“We ultimately had no financial impact on venture fund 1 or 2 or on any of our portfolio funds or our underlying companies,” Guitar tells InnovationMap. “But that is thanks to the Sunday night decision to ensure all deposits.”

On Sunday afternoon, the Federal Deposit Insurance Corp. took control of SVB and announced that all accounts would be fully insured, not just up to the $250,000 cap. Customers like Cisek had access to their accounts on Monday.

“In the shorter term, the great news is SVB entity seems to be largely up and functioning in a business as usual manner,” Guitar says. “And they have a new leadership team, but their existing systems and predominantly the existing employee base is working well. And what we're hearing is that business as usual is taking place.”

Time to diversify

In light of the ordeal, Guitar says Houston founders and funders can take away a key lesson learned: The importance of bank diversification.

“We didn't think we needed one last week, but this week we know we need a resilience plan," she says, explaining that bank diversification is going to be added to "the operational due diligence playbook."

"We need to encourage our portfolio funds to maintain at least two banking relationships and make sure they're diversifying their cash exposure," she says.

A valued entity

Guitar says SVB is an integral part of the innovation ecosystem, and she believes it will continue on to be, but factoring in the importance of resilience and diversification.

"Silicon Valley Bank and the function that they have historically provided is is vital to the venture ecosystem," she says. "We do have confidence that either SVB, as it is currently structured or in a new structure to come, will continue to provide this kind of function for founders."

Cisek, who hasn't moved any of her company's money out of SVB, has similar sentiments about the importance of the bank for startups. She says she's grateful to the local Houston and Austin teams for opening doors, making connections, and taking chances for her that other banks don't do.

"I credit them to really being partners with startups — down to the relationships they connect you with," she says. "Some of my best friends who are founders came from introductions from SVB. I've seen them take risks that other banks won't do."

With plans to raise funding this yea, Cisek says she's already started her research on how to diversify her banking situation and is looking into programs that will help her do that.

Staying aware

Guitar's last piece of advice is to remain confident in the system, while staying tuned into what's happening across the spectrum.

“This situation that is central to the venture ecosystem is an evolving one," she says. "We all need to keep calm and confident in business as usual in the short term while keeping an eye to the medium term so that we know what happens next with this important bank and with other associated banks in the in our industry."

Meet the Texas security experts building a framework for safer schools

For the Kids

For a large portion of his career, Mike Matranga worked as a Secret Service agent protecting the President and First Family all over the world.

He then moved to the Department of the Interior, specializing in domestic terrorism, when the 2018 shooting at Marjory Stoneman Douglas High School occurred. Only three months later, another school shooting happened in Santa Fe, Texas.

That's when Matranga received a phone call from a Texas superintendent, asking him to take his decades of security experience and training and develop a proactive school safety program — something that didn't yet exist. That comprehensive, holistic plan would go on to be ranked No. 1 in Texas and No. 5 in the nation.M6

Mike Matranga, M6 Global M6 Global's Mike Matranga.Photo courtesy of M6 Global

This led Matranga to found M6 Global, which today specializes not only in school safety plans but also programs for industrial and corporate settings and even major sporting events.

The team is comprised of current and former federal agents and security specialists, a psychiatrist, a leading emotional intelligence doctor, a former White House doctor, and emergency management experts. Together, they have more than 100 years combined experience in school safety, law enforcement, and national and global security.

And that's what's made Matranga's initiatives so successful: the people.

“Of all the measures and initiatives we implemented, the absolute most important thing we have are people who have the ability to make real change — which no camera system will provide," he says. "Simply teaching people how to identify pre-attack behavior, self-harm behavior, and a person in crisis will always be what is most important. Secondly, having the resources and courage to intervene once those things are identified will keep individuals off the path to violence. We must never discredit the human element.”

M6 Global also partners with ASAP Security Services in Houston to provide the most up-to-date technology and products, with everything from facial recognition software to cameras to threat detection software. It makes their services fully turn-key, and as Matranga says, "two brains are better than one."

Mike Matranga and President Joe Biden, M6 Global Mike Matranga (left) with President Joe Biden.Photo courtesy of M6 Global

"At some point we have to realize that the law enforcement response that we adopted in the '80s is not working," he adds. "And it’s not just police — it’s the patterns and behaviors of people that will tell you there is a problem, so we need to shift from a reactive to a proactive mindset. We need to have actionable resources in place and a society that's better informed to recognize the signs before someone becomes a person in crisis."

To learn more about M6 Global and explore its services, visit here.

5 most popular innovation stories in Houston this week

what's trending

Editor's note:Another week has come and gone, and it's time to round up the top headlines from the past few days. Trending Houston tech and startup news on InnovationMap included Houston mayoral candidates weighing in on the tech ecosystem, a Houston startup raising funding, and more.

3 Houston innovators to know this week

This week's roundup of Houston innovators includes Joanna Nathan of Prana Thoracic, Alfredo Arvide of Cloche, and Susan Davenport of the Greater Houston Partnership. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health tech to mobile ordering — recently making headlines in Houston innovation. Read more.

8 energy tech startups recognized at Houston's CERAWeek pitch competition

Here's what startups took home wins at CERAWeek. Photo by Natalie Harms/InnovationMap

Over 200 startups participated in CERAWeek this year, and 18 of those companies pitched at a Greater Houston Partnership event.

The Houston Energy Transition Initiative, an initiative to promote Houston's work within the energy transition, hosted its second annual HETI Energy Ventures Competition at CERAWeek Innovation Agora. The competition was divided into four categories. The first batch of startups consisted of five companies from the Texas Entrepreneurship Exchange for Energy, or TEX-E, a collaboration with Greentown Labs, MIT’s Martin Trust Center for Entrepreneurship, and universities across Texas.Read more.

U.K. carbon capture startup sets up new HQ in Houston

Carbon Clean is moving into the Ion for its United States headquarters. Photo courtesy of the Ion

A startup that produces carbon capture technology has set up its U.S. headquarters in Houston. Establishment of the HQ marks the company’s formal North American expansion.

Carbon Clean, based in the United Kingdom, says it will double the size of its U.S. workforce to meet greater demand for its CycloneCC technology. The company expects the U.S. to become its biggest market.

The startup’s technology has captured nearly two million tons of carbon dioxide at almost 50 sites around the world. Carbon Clean says CycloneCC can reduce the cost of carbon capture by as much as 50 percent with a footprint that’s 50 percent smaller than traditional carbon capture units. Read more.

This new partnership will triple Houston's electric vehicle rental fleet

A new initiative from the city of Houston and Hertz aims to boost Houston's electric vehicle rental fleet. Photo via Mayor Sylvester Turner/Facebook

A new partnership between The Hertz Corp. and the City of Houston will bring 2,100 rental electric vehicles to Houston, according to an announcement from the organizations earlier this week.

Dubbed Hertz Electrifies Houston, the program aims to boost Houston's EV rental fleet, as well add to the city's charging infrastructure and EV education and training opportunities.

The new vehicles will come from automakers Tesla, Polestar, and GM and can be rented to leisure and business customers, as well as rideshare drivers. Read more.

Experts address Houston's energy transition role — from research to commercialization

At a recent SXSW panel, four Houston energy experts discussed the importance of research, commercialization, and more in Houston to drive the energy transition. Photo via Getty Images

Every part of the energy industry is going to have a role in the energy transition — from the universities where the research and development is happening to the startups and the incumbent industry leaders, as a recent SXSW panel discussed.

“We are well known in Houston for being the energy capital of the world," Jane Stricker, executive director of the Houston Energy Transition Initiative, says as moderator of the panel. "The industry typically comes together with stakeholders to think about the solutions and how to solve this dual challenge of continuing to provide more energy to the world but doing it in a way that significantly reduces emissions at the same time.”

The panel, entitled "Ground Zero: Creating Pathways from Research to Scale Deployment," was put on by HETI, an organization under the Greater Houston Partnership, and took place Sunday, March 12, in Austin at SXSW. Read more.

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