HOUSTON INNOVATORS PODCAST EPISODE 182

Why this Houston innovator is racing to commercialize its unique treatment for neurodegenerative diseases

For Howard Berman, CEO and co-founder of Coya Therapeutics, commercializing his company is personal. Photo courtesy of Coya

When Howard Berman sought out renowned Houston Methodist researcher and neurologist Dr. Stanley Appel, he was looking for treatment for his father, who was suffering from dementia. He wasn't looking for a job, but Dr. Appel had other ideas and asked Berman to meet with him.

"I was interested in what I could do for my dad," Berman says on the Houston Innovators Podcast, explaining how he took the meeting with Dr. Appel, who then presented him with some of his research. "By slide five my jaw had hit the ground.

"He had shown that he could stop the progression in one of his early trials of ALS," Berman says.

Not too long after that meeting, Berman, who founded digital health platform imaware, joined Dr. Appel to lead commercialization of Coya Therapeutics, a biotech startup that raised over $20 million in venture funding before going public a few months ago.

Coya has developed a biologics therapy that prevents further spreading of neurodegenerative diseases by making regulatory T cells functional again. Diseases like ALS, the company's focus right now, prevent T-regs from doing their job in controlling inflammation, and without these cells hard at work, the human body doesn't stand a chance in fighting autoimmune threats.

Berman, as co-founder and CEO, has been at the helm of the company leading it through both the fundraising and IPO processes. Coya's IPO occured in a tough market — only 12 biotech companies went public last year, he explains. To Berman, that just proves how passionate the team was about getting this product to those who need it.

"It really says something for the fortitude and our team to come together to make it happen," he says on the show. "We're able to deliver and execute in a difficult market climate.

"Once you're a public company, you have different expectations," he continues. "But you also have the opportunity to go out and attract additional investors in ways you can't do as a private company."

For Berman, whose father passed away earlier this year, it's a personal motivation that drives him to lead the company — as well as an opportunity to advance the city of Houston.

"The next number of years as we develop this therapeutic regimen for ALS, we have the potential to transform Houston into something more than it is currently," he says. "Our success will be the city's success."

Berman shares more of the Coya Therapeutics story on the podcast, as well as how he sees Houston's potential as an emerging hub for biotech. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


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Building Houston

 
 

This week's roundup of Houston innovators includes Ramanan Krishnamoorti of UH, Valerie Tompson of SWAN Impact Network, Evan Erickson of TexPower Technologies. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from battery tech to impact inveesting — recently making headlines in Houston innovation.


Ramanan Krishnamoorti,  as vice president of energy and innovation at University of Houston

Natalie Harms

Ramanan Krishnamoorti has had a varied career in academia, from an engineering professor to nanotech research. While he never made the transition from researcher to entrepreneur, he managed to snag a CEO title at the university about a decade ago: Chief energy officer.

Since then his role has expanded to include advancing UH's innovation of all kinds — from health tech to the arts — as vice president of energy and innovation at UH. In his role, he oversees the UH Technology Bridge, a lab and coworking space for tenants just a short drive away from UH's main campus, as well as future plans, like a new central campus hub for innovation that's in its early stages of development.

"What we really need at the university today is to bring innovation — which tech transfer is a piece of — and connect that to real-world challenges to deliver what the world needs, which is talented folks delivering new innovative, entrepreneurial, or intrapreneurial programs," Krishnamoorti says on this week's episode of the Houston Innovators Podcast. Read more.

Valerie Tompson, Houston chapter lead for SWAN Impact Network

Austin-founded SWAN Impact Network has entered the Houston innovation ecosystem. Photo courtesy of SWAN

SWAN Impact Network, which focuses on funding early-stage, impact-driven startups, announced that Houston will be its next market expansion. Founded in 2016 as the Southwest Angel Network, the organization has grown from several investors to over 80 across Texas. The investors, who meet virtually, range from former entrepreneurs, seasoned investors, and first time angels.

Valerie Tompson, who's serving as the Houston market lead, is an example of someone who was drawn to SWAN's mission, even though she had never invested in startups before.

"I was intrigued by the idea of being able to invest in companies that are making a difference in the world — and it's not a charitable donation," she says, explaining that joining a network allowed for her to learn the ropes and understand the process. Read more.

Evan Erickson, co-founder and CEO of TexPower

A Houston startup founded off research out of a Texas university has cut the ribbon on its new lab space. Photo courtesy of TexPower

TexPower EV Technologies Inc. celebrated the opening of its 6,000-square-foot laboratory and three-ton-per-year pilot production line at a ribbon-cutting event last week. The Northwest Houston site is located at 6935 Brittmoore Rd.

TexPower spun out of the University of Texas at Austin in 2019. The company was co-founded by Erickson with CTO Wangda Li and Board Chairman Arumugam Manthiram, a professor at UT whose lithium-ion battery research fuels the foundation of the company.

“We want to point out how lucky we are — as a company and as scientists," Erickson says at the ribbon cutting event. "It’s not common that you see something you work on in academia turn into something that can become commercially successful.” Read more.

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