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Houston biotech company closes IPO in $15.25M deal

A Houston biotech startup focused on developing therapeutics for neurodegenerative and autoimmune diseases has closed its IPO. Photo via Getty Images

A clinical-stage biotech company based in Houston has announced the closing of its $15.25 million IPO.

Coya Therapeutics, now trading under the ticker COYA, announced this week that its IPO — previously disclosed in December — has closed its initial public offering of 3,050,000 shares of its common stock and accompanying warrants to purchase up to 1,525,000 shares of common stock, per a news release.

The company is developing proprietary therapies to enhance the function of regulatory T cells to target systemic inflammation and neuroinflammation.

According to the company, the net proceeds from the offering — which was estimated to be at around $13.2 million, per a release — will go toward advancing its programs in preclinical studies into clinical trials — as well as to advance its discovery and candidate selection stage programs and other scaling purposes.

In 2021, Coya Therapeutics announced that it had merged with Nicoya Health Inc. and raised $10 million in its series A. The round was led by Florida-based Allele Capital Partners LLC. Howard Berman, founder and board of directors for imaware, was named the CEO of Coya, as well as a member of the company's board of directors, alongside the merger and series A announcement.

Coya's therapeutics uses innovative work from Dr. Stanley H. Appel, co-director of Houston Methodist Neurological Institute and Chair of the Stanley H. Appel Department of Neurology at Houston Methodist Hospital. The researcher has created a way to "isolate dysfunctional Tregs from a patient, convert them to a highly functional and neuroprotective condition, and expand these cells into the billions for intravenous reinfusion back to the patient," says Berman in a 2022 news release. This revolutionary work overcomes previous limitations in the field.

"Patients with neurodegenerative diseases are in desperate need of transformative therapeutic options; harnessing the neuroprotective effects of Treg cell therapy shows great potential in unlocking a new treatment paradigm and may enable us to revolutionize care for patients with devastating neurodegenerative diseases," Appel said last February. "We have successfully demonstrated, in a phase 1 trial, the safety and tolerability of autologous infusions of expanded Tregs in ALS patients, with the potential of slowing or halting disease progression. Ongoing studies provide a transformative framework for advanced clinical trials in ALS and other neurodegenerative disorders."

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Building Houston

 
 

Check out this curated list of innovation events in Houston for February. Photo via Getty Images

It's time to look at what's on the agenda for February for Houston innovators — from pitch competitions to networking events.

Here's a roundup of events not to miss this month. Mark your calendars and register accordingly.

Note: This post might be updated to add more events.

Feb. 8 — Digital Marketing Luncheon

Join Insperity, a partner of The Cannon, and digital marketing expert, Danny Gavin, at The Cannon Downtown for a lunch and learn.

The event is Wednesday, February 8, at noon, at The Cannon Downtown. Click here to register.

Feb. 9 — Innovation on Tap: Fred Higgs, Engineering at Rice University

Discuss research in the speaker’s engineering lab at Rice University on key Industry 4.0 technologies, namely additive manufacturing.

The event is Thursday, February 9, at 4 pm, at the Ion. Click here to register.

February 10 — Women in Leadership Conference 

The 23rd annual Women in Leadership Conference will be held in-person at Rice University. The conference has been a beacon of inspiration in the Houston community, empowering women to accomplish their career goals. In panel discussions and interactive workshops, attendees hear from leaders across different industries, explore various approaches to leadership, and discuss future opportunities for success.

The event is Friday, February 10, at 8 am, at McNair Hall at Rice University. Click here to register.

Feb. 15 — Real Talk from Real VCs

Join this event for a candid fireside chat on venture capital and its role in supporting and growing innovative startups.

The event is Wednesday, February 15, at 5:30 pm, at the Ion. Click here to register.

Feb. 16 — Engage VC: Lerer Hippeau

Lerer Hippeau is an early-stage venture capital firm founded and operated in New York City. Since 2010, they have invested in entrepreneurs who embody audacity, endurance, and winning mindset – good people with great ideas who aren't afraid to do hard things. Join the HX Venture Fund to hear Caitlin Strandberg, Partner at Lerer Hippeau discuss her perspective on how to build and scale a great company, what early-stage investors are looking for, why Houston, and market trends among other topics.

The event is Thursday, February 16, at 8:30 am, at the Ion. Click here to register.

Feb. 16 — Female Founders and Funders

Calling all rockstar female founders and investors in the Houston area. Mark your calendars for this month's Female Founders and Funders meetup. Coffee and breakfast is provided and the event is free to attend.

The event is Thursday, February 16, at 9 am, at Sesh Coworking. Click here to register.

Feb. 21 — Web3 & HOU: Demystifying the Web3 Space Panel I

Join us to learn more about Web3 and its numerous applications.

The event is Tuesday, February 21, at 6 pm, at the Ion. Click here to register.

Feb. 22 — The Trailblazer’s Guide to Cultivating Authenticity

In this fun and interactive workshop presented by Erica D’Eramo of Two Peirs Consulting, we’ll look at how to foster a leadership style that works for you, even in the absence of role models.

The event is Wednesday, February 22, at 2 pm, at Sesh Coworking. Click here to register.

Feb. 22 — Houston Startup Showcase

The Houston Startup Showcase is a year-long series of monthly pitch competitions. Founders will pitch at the Ion and compete for the grand prize package. Watch the startups pitch their company and see who the judges will name the champion of the Houston Startup Showcase 2023.

The event is Wednesday, February 22, at 6 pm, at the Ion. Click here to register.

Feb. 23 — Navigating Innovation in the Corporate World

Join us for a fireside chat with leaders from Houston's largest employers, including Microsoft and Chevron to discuss how they have navigated successful careers in technology and innovation.

The event is Thursday, February 23, at 11:30 am, at the Ion. Click here to register.

Feb. 27-March 2 — Houston Tech Rodeo

The Houston Tech Rodeo is a conference showcasing the best and brightest of the Houston startup community in the region and beyond by putting investors, entrepreneurs, industry leaders, and creative minds in a room to talk about the biggest innovations and the future of tech sandwiched by some happy hours and friendly competition.

The events run Monday, February 27, through Thursday, March 2, at various locations in Houston. Click here to register.

Note: This post might be updated to add more events.


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