Overheard: Houston Innovation Awards finalists share top advice for fellow founders

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Fifteen of Houston Innovation Awards finalists share the best advice they've given or received. Photo via Getty Images

The startup journey is a long and winding road, and there's many ways to navigate it. Fifteen of this year's finalists have shared what their most valuable startup advice for their fellow Houston founders.

From the importance of mentorship to tips for female and BIPOC founders, these pearls of wisdom come directly from a selection of finalists across a handful of categories, including DEI Champion, BIPOC-Owned Business, Female-Owned Business, and Mentor of the Year.

Read these excerpts of advice from Houston's innovation community's top startup founders and supporters.

Click here to secure your tickets to the November 8 event where we'll name the 2023 Houston Innovation Awards winners.

"Be comfortable with asking for and accepting help. This journey is a marathon, not a sprint, but helping yourself with supportive people around is critical." — Cameron Carter of Rosarium Health, a BIPOC-Owned Business finalist

"Underrepresented founders often have trouble asking for what they want or deserve. ... Don't be scared to ask for what you want, or what you believe you deserve." — Pedro Silva of Milkify, a BIPOC-Owned Business finalist

"It's not 'fake it' until you make it. It's 'take it' until you make it. Be proud to be you." — Pamela Singh of CaseCTRL, a BIPOC-Owned Business finalist

"When starting a company, remember it’s a game of attrition. The best way to last longer than your nearest neighbor is to find your tribe." — Aaron Fitzgerald of Mars Materials, a BIPOC-Owned Business finalist

"Know your worth and add tax. Choose your partners wisely — at home and work. Invest in the best stock you own: YOU." — Katie Mehnert of ALLY Energy, a Female-Owned Business finalist

"Whatever battle you're fighting now that no one knows about — go ahead and WIN the war." — Shoshi Kaganovsky of Feelit Technologies, a Female-Owned Business finalist

"My advice would be to find truly effective mentors who are willing to open up their network for you. It doesn't matter if the mentors are men or women — what matters is that they genuinely care about your professional success and who you are as a person." — Tatiana Fofanova of Koda Healthcare, a Female-Owned Business finalist

"Remember...There are a BILLION ways to apply sunscreen, but no matter how you apply it, it ALL protects you from the sun. Like sunscreen, there are infinite ways to succeed in the startup world. Trust your gut, stick to your vision, and keep trying until you find what works for you. ... Your purpose and vision should be your North Star, guiding decisions in team-building, coaching, and creating a company culture. Stick to that purpose—it's what will drive you through the rollercoaster of entrepreneurship." — Emily Cisek of The Postage, a Female-Owned Business finalist

"First and foremost, embrace your uniqueness. As a woman of color, you bring a distinctive perspective to the table. Your background is not just a part of who you are; it's a strength that sets you apart in a male-dominated industry. ... Resilience is your greatest ally. Challenges will arise, and it's okay to acknowledge them. What matters most is how you respond. Each obstacle is an opportunity for growth and learning. ... Lastly, trust yourself. You are not just running a business; you are shaping a narrative of empowerment and change." — Ghazal Qureshi of UpBrainery Technologies, a Female-Owned Business finalist

"Figure out, learn, and understand your mission inside and out and use it to make all your major business (and sometimes personal) decisions." — LaGina R Harris, founder and CEO of The Us Space and Mentor of the Year finalist

"Know your value and continue advocating for inclusion." — Janice Tran of Kanin Energy, a BIPOC-Owned Business finalist

"Be your true, authentic self. There are going to be some people that like what you are doing, and there's going to be some people that don't, but the biggest thing is being true to who you are, and that's always going to flourish more than being who someone else wants you to be." — Muriel Foster, director of gBETA Houston and Mentor of the Year finalist

"Until you hire someone, you are the one wearing the product manager hat. You've got to love the problem more than the solution." — Wade Pinder, founder of Product Houston and Mentor of the Year finalist

"Be the person your younger self needed. Representation really does matter. Be a listening ear, share your lessons, and allow people to blossom under your leadership." — Michelle Ngome, founder and president of the African American Marketing Association and DEI Champion finalist

"Embrace your unique perspective as a source of strength and innovation. ... In Houston's dynamic startup scene, your presence and contributions as a traditionally marginalized founder or investor are essential for driving innovation and diversity. By staying resilient, seeking support, and advocating for inclusivity, you can navigate the entrepreneurial journey and make a lasting impact on both your business and the broader community." — Jessica Adebiyi, diversity and professional development director at Womble Bond Dickinson and DEI Champion finalist

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Want to work for one of the top startups in Houston? Some of the best in Houston are hiring. Photo by Tima Miroshnichenko from Pexels

Looking for a job? These 2023 Houston Innovation Awards finalists are hiring

calling all applicants

More than half of this year's startup finalists in the Houston Innovation Awards are hiring — who's looking for a job at one of the best startups in Houston?

When submitting their applications for the 2023 Houston Innovation Awards, which is taking place November 8 at Silver Street Studios, every startup was asked if it's hiring. Twenty-seven of the 35 startup honorees said yes, ranging from over 20 to just one positions open at each company.

Click here to secure your tickets to see which of these growing startups win.

Here's a look at which of the top startups in Houston are seeking new team members.

Double-digit growth

When it comes to the awards finalists looking to scale their team by 10 or more new hires, five finalists are growing rapidly.

Medical practice software platform RepeatMD, fresh off a $40 million raise — which included participation from Houston-based Mercury — is reportedly growing its team. The company, which has 115 employees already, is looking for over 20 new hires.

Female-owned business Feelit Technologies, which is using nanotechnology for preventive maintenance to eliminate leaks, fires and explosions, increase safety and reduce downtime, has 50 employees, and only three of which are in Houston – for now. The company hopes to grow its team by 12 to 15 employees in Houston alone.

Square Robot, an energy industry-focused robotics company that recently grew its presence in Houston, is hiring 10 to 30 new team members. It has 24 employees already in Houston.

Solugen, an alternative chemicals business, has around 140 of its 200 employees in Houston. The company, which has raised over $600 million to date, is hiring an additional 10 to 15 new hires.

Additionally, Blue People, also a finalist in last year's awards, is hiring 25 new employees. The company was founded in 2015 in Mexico and relocated its primary operations to Houston in 2020. Blue People, which develops software innovation for its clients, has over 150 employees — 10 of whom, including C-level executives, are based in Houston. Some of the company's new hires will be based in town.

Steady growth

Four Houston startups are hiring within the six to 10 team member range — all with fairly significant employee counts already.

A finalist in last year's awards too, Venus Aerospace, a hypersonics company on track to fly reusable hypersonic flight platforms by 2024, is again growing its team. With 48 on-site employees and 23 working remotely, Venus's team will add another five to 10 employees.

Syzygy Plasmonics, a deep decarbonization company that builds chemical reactors designed to use light instead of combustion to produce valuable chemicals like hydrogen and sustainable fuels, has 112 employees in Houston and plans to hire another eight to its team.

Lastly, Fervo Energy, which recently raised $10 million, has 63 full-time employees (34 in Houston, 29 outside of Houston) and looking to hire seven more.

Seeking selectively

The following awards finalists are looking to grow their teams by just a handful or so — between one and five — of new hires:

  • ALLY Energy, helping energy companies and climate startups find, develop, and retain great talent.
  • CaseCTRL, an AI-powered surgery scheduling and coordination software for optimized procedures.
  • CellChorus, using AI to evaluate immune cell function and performance to improve the development and delivery of therapeutics.
  • FluxWorks, making frictionless gearboxes for missions in any environment.
  • Helix Earth Technologies, decarbonizing the built environment and heavy industry.
  • Hope Biosciences, a clinical stage biotechnology company focused on the development and delivery of adult stem cell based therapeutics.
  • Innovapptive, empowering the deskless workers in operations, maintenance and warehouses by unlocking the power of SAP through mobility.
  • INOVUES, re-energizing building facades through its non-invasive window retrofit innovations, making building smarter, greener, and healthier for a better and sustainable future.
  • Koda Health, , a tech-enabled care coordination service to improve serious illness care planning and drive savings for value-based care at scale.
  • Molecule, an energy/commodity trading risk management software that provides users with an efficient, reliable, responsive platform for managing trade risk.
  • Rhythm Energy, 100 percent renewable electricity service for residential customers in Texas.
  • Starling Medical, bringing the future of a proactive and predictive home-based healthcare system to patients today through passive AI powered at home urine screening.
  • Taurus Vascular, pioneering a new era of aortic aneurysm treatment by developing minimally invasive catheter solutions to drive better long-term patient outcomes.
  • Tierra Climate, decarbonizing the power grid faster by helping grid-scale batteries monetize their environmental benefits and change their operational behavior to abate more carbon.
  • UpBrainery Technologies, an innovative educational technology company that provides personalized and adaptive learning experiences to learners
  • Utility Global, a technology company converting a range of waste gases into sustainable hydrogen and syngas.
  • Voyager Portal, helping commodity shippers identify root causes of demurrage, reduce risk and streamline the entire fixture process.

Three female-founded health tech startups won awards at this year's Ignite Healthcare's Fire Pitch Competition. Photo courtesy of Ignite

Houston health tech startup wins female-focused pitch competition

women in health care

For the fourth year, a Houston-based, female-focused health tech organization has spotlighted the industry's emerging technology entrepreneurs.

Earlier this month, Ignite Healthcare Network’s Accelerator Program hosted its seven women-led digital health startup finalists, narrowed down from over 330 startups, at its annual Fire Pitch Competition. The nonprofit is led by a group of women executives committed to shaping the future of health care.

“The fourth year of Ignite Health’s Accelerator Program has proved to attract more and more women founders of digital tech and med device startups from around the world,” says Ayse McCracken, Ignite's founder, in a news release.

According to McCracken, 22 applicants made it into the program, which launched earlier this year. A group of judges narrowed down that group to seven finalists, before announcing the top three companies for the competition.

Joanna Nathan, CEO of Houston-based Prana Thoracic, won the top award for her company. Stephanie Gravenor, founder of Denver-based Medecipher, and Liane Clamen, founder of Chestnut Hill, Massachusetts-based Adaptilens, won second and third, respectively.

The event doled out over $500,000 in total. Jay Goss, general partner of Wavemaker Three-Sixty Health, announced $100,000 investments into four finalists' companies. The finalists receiving this award are:

  • Pamela Bonnett, CEO of Denver-based Ultrasound AI
  • Christine Lum Lung, co-founder and CEO of Fort Collins, Colorado-based Origin Healthcare
  • Pamela Singh, co-founder and CEO of Houston-based CaseCTRL
  • Stephanie Gravenor, founder and CEO of Denver-based Medecipher

The partner organizations participating in this year's accelerator and event included Houston Methodist, Memorial Hermann Health System, Texas Children’s Hospital, Texas Children’s Pediatrics, The Menninger Clinic, HCA, Kindred Healthcare, Aetna, Texas Health Resources, Cook Children’s Hospital, TMC, Golden Seeds, Wavemaker 360 Health, Portfolia, Prosalus, 7Wire, Texas Halo Fund, Unity Point Ventures, and others.

“We are grateful for the support and generosity of our sponsors for helping to make this event possible,” says Cheryl Stavins, Ignite board member and co-chair of the event, in the news release. “Their support and involvement continue to ignite our mission and passion to ensure the success and recognition of women entrepreneurs in healthcare.”

Earlier in the day, Ignite Health hosted a new event called “Women Shaping the Future of Healthcare Luncheon." Eighty female executives, investors, founders, and community leaders gathered to hear from three of Ignite Health’s alumni founders: Somer Baburek, CEO of Hera Biotech, Dr. Liz Clayborne, CEO of Nasaclip, and Amanda Gorman, chief clinical officer of Nest Collaborative.

This week's roundup of Houston innovators includes Pamela Singh of CaseCTRL, Ahmad Atwan of VC Fuel, and Maggie Segrich of Sesh Coworking. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health tech to energy venture capital — recently making headlines in Houston innovation.


Pamela Singh, co-founder and CEO of CaseCTRL

Pamela Singh joins the Houston Innovators Podcast to discuss what's on the horizon for her health tech company. Photo courtesy of CaseCTRL

When COVID-19 shutdown all elective surgeries, Pamela Singh didn't know what would happen to her startup, CaseCTRL, which uses AI to optimize surgery scheduling. But, the back and forth nature of surgeries being allowed then not made for a huge need for CaseCTRL's platform to help medical facilities get back on track.

"COVID has had some sort of silver lining for us," Singh says, explaining that surgical facilities were looking for a way to catch up. "They realized the need for automating and streamlining their practice. And they realized that, instead of spending another four hours coordinating with patients and vendors, they could literally do it with the click of a button."

Singh shares more about her entrepreneurial journey and what's on the horizon for CaseCTRL, as well as her advice for fellow female founders in the podcast. Click here to read more and stream the full interview.

Ahmad Atwan, founder and CEO of VC Fuel

Ahmad Atwan founded VC Fuel in Houston to fund the future of the energy transition. Photo courtesy of VC Fuel

When Ahmad Atwan decided he was going to launch VC Fuel, a venture capital fund focused on early-stage energy transition startups, deciding where to start was easy. While there are similar funds on each of the coasts, Atwan learned that VC Fuel's concept was going to be kind of niche for Houston.

"Houston is the undisputed energy capital of the world," he tells InnovationMap. "So to me, especially when you're looking at energy transition sectors that have to work with the energy industry, it was a no brainer."

Atwan shares more about VC Fuel and the $100 million fund, which he's still raising for while also investing in a few startups at the same time, in an interview with InnovationMap. He also discusses how his expertise as a former founder and former private equity investor with Morgan Stanley and BlackRock makes him an opportune value-add investor. Click here to read more.

Maggie Segrich, co-founder and CFO of Sesh Coworking

Maggie Segrich (right) opened Sesh with Meredith Wheeler in 2020. Photo courtesy of Sesh

Maggie Segrich co-founded Sesh Coworking and the duo opened its first space in early 2020. Now, 18 months later, Sesh is growing. The female-founded, female-focused coworking company has also launched a crowdfunding campaign to support Sesh's growth.

The new coworking space is set to be in Midtown, but Sesh hasn't yet announced the specific location. The plan is to open to members at the beginning of 2022. The move will allow Sesh to offer private offices and dedicated desks, as well as other amenities members are looking for.

"Sesh never set out to be like other coworking spaces," she says. "We are on a mission to create a work space that isn't just four walls and a door. We began in 2017 by building our community first through pop-ups and then with our current space in Montrose. This new space carries on that tradition and mission of putting community first." Click here to read more.

Pamela Singh, co-founder and CEO of CaseCTRL, joins the Houston Innovators Podcast to discuss what's on the horizon for her health tech company. Photo courtesy of CaseCTRL

Houston startup with AI-optimized surgical scheduling technology is ready to scale

houston innovators podcast episode 101

With so many moving parts in the health care industry, Pamela Singh says patients can go through all the pre-operation steps up to literally arriving to the hospital, only to find out their surgery has been canceled due to an admin error.

Singh's startup, which she founded with her husband and surgeon Dr. Ashvin Dewan, CaseCTRL is looking to prevent these surgical scheduling inefficiencies. On this week's episode of the Houston Innovators Podcast, Singh explains how the idea for the company came from an organic need Dr. Dewan saw in his practice.

"We decided there needs to be a better way to help surgeons, schedulers, and patients to have a better experience," Singh, who serves the company as CEO, says on the show. "Surgery is the highest revenue-generating event for any hospital, clinic, or private practice. And your patients are essentially your customers, so you need to give them the best patient experience."

CaseCTRL started with this patient-focused goal, but throughout development, Singh says she realized the overall effect of optimization. Especially, she says, when it came to COVID-19's effect on surgery scheduling. The company got its start amid the pandemic, and wasn't sure how the cancelation of elective surgeries was going to impact the startup's journey. But really, with the backlog of surgeries building up over different periods of stopping and restarting surgeries, a rising need for optimization emerged.

"COVID has had some sort of silver lining for us," Singh says, explaining that surgical facilities were looking for a way to catch up. "They realized the need for automating and streamlining their practice. And they realized that, instead of spending another four hours coordinating with patients and vendors, they could literally do it with the click of a button."

Now, in light of this growing need and awareness, Singh and her team is ready to scale. She says she is working with her team on integration opportunities and building out the tech to make it even more convenient to use.

Currently, the company is in the process of completing its Techstars accelerator and raising pre-seed funding. CaseCTRL was a member of gBETA Houston's second cohort and has pitched at several Houston innovation ecosystem events. Singh was even an inaugural finalist for the 2021 InnovationMap Awards. She says she's been surprised by how supportive Houston has been.

"The community here is diverse and, most importantly, supportive," Singh says, adding that at first they wondered if Houston had too much health care innovation and competition. "We realized the community in Houston ... really wants to see you succeed. The biggest pro is that entrepreneurial spirit here in Houston."

Singh shares more about her entrepreneurial journey and what's on the horizon for CaseCTRL, as well as her advice for fellow female founders in the podcast. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


The five finalists in the Top Founder Under 40 category for the inaugural InnovationMap Awards share the challenges they have had to overcome. Photos courtesy

Overheard: Young founders explain the challenges they've faced

Eavesdropping in houston

It's not easy being the youngest person in a room, and that's certainly the case for startup founders looking to make an impact on an industry that's been doing things a certain way since before they were born.

The five finalists of the Top Founder Under 40 category for the InnovationMap Awards presented by Techwave were asked to share their challenges overcame as young founders. Here's what they had to say. Click here to register for the livestream.

"It wasn't until I stood my ground by being persistent, and by not being afraid to hand their responsibilities to someone else, that they finally took me seriously."

Photo courtesy of CaseCTRL

— Pamela Singh of CaseCTRL says. "While working as on a Department of Defense Contract, I was leading a development effort with other older white men who were mostly retired military," she explains."They did not appreciate a young ethnic female giving them orders, and would often ignore my email requests or assigned tasks. At first, I felt defeated, but then I had to remember that although they have a lot of knowledge in general, I was the one with the right knowledge for this specific project."

"Changing the minds of experienced executives, who have worked in the energy industry for decades, was an uphill battle that took time and a considerable amount of effort."

With fresh funds, this Houston entrepreneur plans to scale his industrial e-commerce startup

Photo by Colt Melrose for GoExpedi

— Tim Neal of GoExpedi. "Over the years, I have enjoyed great success in my professional career, but that has not come without a few challenges," Neal says. "I am incredibly grateful for my mentors who believed in my vision despite my age."

"I think my go getter attitude has always helped me out and aid me mature faster."

Photo courtesy of LAMIK Beauty

— Kim Roxie of LAMIK Beauty. "Since I started at such young age at 21, after being labeled 'at risk' in high school, I think I have always been seen as 'too young,'" she says. "However, My life motto is 'qualify yourself!'"

"Once I started just being myself and not carrying the weight of the no's it really improved my productivity, my leadership, and my overall success as a person and as a leader in my business."

Emily Cisek, CEO and co-founder of The Postage

Photo courtesy of The Postage

— Emily Cisek of The Postage. "I think advocating for myself and my business as a younger female founder has been a challenge mostly because as a person you want to please the people around you, investors, whoever, and sometimes no matter what you do, they aren't going to be on the same page and that's OK," she says. "But not carrying that forward is what's important. There's been times I've been told no, when I was trying to be exactly what I thought an investor or business partner wanted to hear."

"Typically, companies that have been around and have older leadership can have an advantage."

Photo via TMC.edu

— Emma Fauss of Medical Informatics Corp. She says she's experienced age discrimination early on within the health care industry.

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Axiom Space expands executive team with two C-suite hires

new leaders

Fresh off officially making Texas its legal headquarters, Axiom Space has named two new C-level executives.

The Houston-based spacetech company, which is developing the first commercial space station, announced earlier this month that it had appointed Zach Gitomer as its new chief financial officer and Erick Wegerer as chief information officer.

Gitomer served as vice president of investor relations and capital markets for Axiom from March to June of this year. Before joining Axiom, he held various leadership roles at Bank of America, Merrill Lynch, and Citi, where he supported technology and growth companies, according to Axiom.

"Building era-defining space infrastructure and pioneering the orbital economy is a complex endeavor that requires not just an audacious vision and stellar engineering talent, but the financial infrastructure, discipline, and capital strategy to match," Gitomer shared in a LinkedIn post. "I’m honored to take on this role ... I’m looking forward to partnering with the exceptional leadership team here at Axiom Space during a defining chapter for the company and commercial spaceflight broadly, as well as a crucial period for maintaining U.S. human presence in low-Earth orbit and leadership in space exploration."

Wegerer joins Axiom after most recently serving as CIO of Washington-based Insitu Inc., a subsidiary of Boeing that develops customized unmanned hardware for commercial, government and defense customers.

"My time at Insitu was defined by talented people, meaningful challenges, and work that mattered. I'm grateful for the teams, partners, and leaders who made progress there possible. Stepping into Axiom, I'm energized by the mission, the momentum, and the opportunity to help shape what's next," Wegerer shared.

Photo via LinkedIn

The duo was celebrated on the floor of the New York Stock Exchange last week.

“We are pleased to welcome these exceptional leaders to the Axiom Space team," Axiom CEO Jonathan Cirtain added in the announcement. “Their strong record of helping complex organizations advance their strategic priorities will strengthen our executive team to further advance our core business objectives."

It's been a busy summer for Axiom. The company tacked on an additional $175 million to a previously announced capital raise, bringing the oversubscribed round to a total of more than $525 million, in June.

It also announced plans to open a Japanese subsidiary July 1. It tapped veteran Japanese astronaut Koichi Wakata to lead Axiom Space Japan as chief technology officer in the Asia-Pacific region. It also shared plans to establish Axiom Space Switzerland, a wholly owned subsidiary based in Lucerne that is also expected to begin operations this summer.

Axiom also officially redomiciled its legal headquarters from Delaware to Texas last month. Read more here.

Houston hardtech accelerator names 8 founders to 2026 cohort

hardtech fellows

Hardtech-focused organization Activate has named 50 new members to its 2026 cohort of scientists, which includes eight startups joining Activate Houston.

Activate aims to support scientists at "the outset of their entrepreneurial journey." It partners with U.S.-based funders and research institutions to support its fellows in developing high-impact technology. Its fellows receive a living stipend, research and development funding, connections from Activate's robust network of mentors and access to a curriculum specific to the program for two years.

This year's fellows represent 41 companies from 22 U.S. cities and 11 states.

“This cohort clearly demonstrates that the next industry-defining companies won't choose between modern technology and deep science; they'll be built by combining both,” Cyrus Wadia, CEO of Activate, said in the announcement. “These are the scientists and engineers turning our most urgent global challenges into the companies that will deliver a more sustainable future.”

The Houston fellows are working across the energy, space, AI infrastructure and agriculture sectors. They include:

  • Sophie Clare Broun, founder of Anning Corporation, which is producing clean hydrogen by stimulating naturally occurring geologic deposits
  • Kathy Andersen, founder of Brint Tech, which builds optical sensing systems that quantify hydrogen for infrastructure operators
  • Dorsa Talebi, founder of Kinetiq Drive, which builds rare-earth-free, contact-free electric motors with wireless rotors for small appliances and heavy industry alike
  • Neethu Pottackal, founder of Nivera, which is developing natural, edible coatings made from agricultural byproducts to reduce food waste and extend the shelf life of fresh food
  • Jonathan Huffman, founder of Orbital Arc, which is shrinking spacecraft propulsion to a microchip powerful enough for deep space
  • Tim Lee, founder of Renesin, which develops advanced materials for faster, more efficient AI hardware
  • Joshua Livingston, founder of Selerra Separations, which is developing high-performance membranes that cut the cost and energy consumption of water treatment
  • Wenli Jiang, founder of SwieNitro Recovery, which is developing technology that converts nitrogen-rich waste streams into valuable fertilizer

"Home to the largest concentration of engineers in the United States and a dense ecosystem of Fortune 100 and Fortune 500 companies, Houston is uniquely positioned for scientists tackling large-scale industrial challenges. Activate Houston fellows are connected to the city's deep networks in energy, chemicals, and materials," Activate said in the announcement.

Activate named its inaugural Houston cohort in 2024. It has other hubs in Boston, New York, and Berkley, California—where Activate is headquartered. The organization also offers a virtual and remote cohort, known as Activate Anywhere. Nationally, it has supported 346 fellows and 276 companies since 2015.

Activate Houston is led by managing director Jeremy Pitts, who co-founded Greentown Labs in Boston. It is based out of the Ion. The latest cohort is Activate Houston's third. Read more about the last year's cohort here.

Rice, Houston Methodist award $90K for cancer research projects

seed grants

Rice University’s Synthesis X Center, in partnership with the Houston Methodist Neal Cancer Center, announced earlier this month the organizations would award $90,000 in seed grant funding to two projects that could help fight cancer. One would ease the pain of chemotherapy, while the other could change the way the progression of leukemia is tracked.

“We’re excited to be collaborating with the Neal Cancer Center to support collaborative, novel and interdisciplinary proposals to improve cancer care and outcomes,” Han Xiao, Rice professor of chemistry and the director of the SynthX Center, said in a news release. “Together, we can achieve translational excellence.”

The projects

Chemotherapy is one of the most effective cancer treatments, but it can be hard on the body. The human body doesn’t like being injected with radioactive material, especially the skin around the injection point, which can become extremely irritated. For patients in long-term treatment, the skin irritation can be more than just a bother; it can lead to infections that are dangerous to a compromised immune system.

Angel A Marti, a professor of chemistry at Rice University, and Biana Godin, an associate professor of nanoscience at Houston Methodist Research Institute, are experimenting with metal nanoclusters as a way to block radiation at the injection site. The nanocluster could be applied in a cream or a gel on the skin, serving as a type of shield against the harsh radioactive material.

Meanwhile, Yuan Ma, an assistant professor of chemistry at Rice, and Shu-Hsia Chen, a professor of immunology at Houston Methodist Research Institute, are working with m6A. Discovered in the 1970s, m6A is the most prevalent chemical modifier found in mRNA in mammals. It is prevalent in many cancers, including leukemia.

Ma and Chen are working on measuring the amount of m6A in leukemia to see if it can determine the most effective cancer treatments. The team is also experimenting with ways to shut off m6A to see if it makes current leukemia treatments more effective.

Progress from SynthX

SynthX was first launched in April 2024 to turn research from Rice and Houston Methodist into real-world cancer treatments. Within a year, the center had secured $1.5 million in grant money to work on crossing the blood-brain barrier in brain cancer treatments. These latest awards show that SynthX Center continues to bridge the worlds of research and clinical practice.

“This collaboration reflects a shared commitment to team science in cancer research,” Daniela Matei, the director of the Houston Methodist Neal Cancer Center, added in the release. “These are the types of translational and pioneering projects that lead to transformation in patient care.”'

The SynthX Center awarded $90,000 in seed grants to three teams in 2025 and $80,000 to three teams in 2024.

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