Here's which life science companies — in Houston and beyond — are ones to watch. Photo by Dwight C. Andrews/Greater Houston Convention and Visitors Bureau

Last week, the Rice Alliance for Technology and Entrepreneurship gathered over 1,000 life science experts and attendees virtually for thought leadership as well as 40 company presentations.

The three-day 2020 Virtual Texas Life Science Forum was made possible through a partnership with BioHouston and support from Texas Medical Center and Insperity. At the close of the summit, several companies were recognized with awards.

Houston-based Starling Medical won the Michael E. DeBakey Memorial Life Science Award, established by BioHouston in honor of the groundbreaking Houston cardiovascular surgeon. The digital health device company is revolutionizing severe bladder dysfunction management with artificial intelligence.

Every year at the forum, the Rice Alliance names its 10 most promising companies working on developing innovative solutions in medical devices, digital health, diagnostics, pharmaceuticals, and therapeutics. This year, Brad Burke, managing director of the Rice Alliance, says they had more applications to present than ever before. Additionally, the presenting companies — about half of which are Houston-based — have already raised more than $275 million in funding.

The 2020 most-promising life science companies, which were chosen by investors and presented by the Greater Houston Partnership, were:

Droice Labs

Image via droicelabs.com

New York-based Droice Labs, is an artificial intelligence and big data company matches patients to therapies and delivers personalized medicine at scale while reducing costs.

"Our cutting-edge technology seamlessly integrates into clinical workflows, and we continue to evolve unique and powerful applications for our clients and the patients they serve," reads the company's website.

SFA Therapeutics

Image via sfatherapeutics.com

Based in Jenkintown, Pennsylvania, SFA Therapeutics is developing oral drugs for treating conditions of chronic inflammation that have the potential to change the practice of medicine. The company has treatments for Psoriasis, Liver Cancer (Hepatitis B, NASH and HCC), Ophthalmic Diseases, Cytokine Release Syndrome- a side effect in CAR-T, Prevention of Relapse/Recurrence in Leukemias, and other diseases.

Hummingbird Bioscience

Photo via jlabs.jnjinnovation.com

Hummingbird Bioscience, based in Houston's JLABS @ TMC, is tackling challenging targets that play a key role in disease yet have not been effectively drugged. The company has worked on 12 therapies in various stages of development, four of which have the potential to revolutionize their fields.

"At Hummingbird, we believe that modern approaches to systems biology and data science can overcome the challenges of classical methods of therapeutics discovery, and profoundly improve the way we deliver new transformative medicines," reads the company website.

CaseCTRL

Image via casectrl.com

Houston-based CaseCTRL is empowering surgeons with a management platform with software-as-a-service technology that uses AI and logistics to lower operational costs and simplify surgical planning.

"The surgical scheduling process is frustratingly stuck in the past: siloed, paper-based, and too dependent on single schedulers," reads the website. "Surgeons are stressed and overworked. They need a better way to communicate their complex surgical plans, timelines and resource needs."

Perimeter Medical

Image via perimetermed.com

Perimeter Medical, based in Dallas, is driven to transform cancer surgery with advanced, real-time, ultra high-resolution imaging tools including AI to address areas of unmet medical need.

"Perimeter is dedicated to providing solutions that drive better patient care and lower healthcare costs by providing critical information, during clinical procedures," reads the website.

Studio Bahria

Image via studiobahia.org

San Antonio-based Studio Bahia, is developing an accessible model for therapy in addressing mental health crises from the pandemic through virtual reality.

"We are in production of our first two therapies for release in the 4th quarter of 2020. Studio Bahia clients include corporate, retail, and institutional partners who purchase our headsets for $25 in providing mental health therapies and wellness tools to employees, executives, and patients," reads the company's website.

Tvardi Therapeutics

Photo via Getty Images

Tvardi Therapeutics, based in Houston, is a clinical-stage biopharmaceutical company focused on the development of a new class of breakthrough medicines for diverse cancers and chronic inflammatory and fibrotic diseases.

"Tvardi is focused on the development of orally delivered, small molecule inhibitors of STAT3, a key signaling molecule positioned at the intersection of many disease pathways," reads the website.

Koda Health

Image via kodahealthcare.com

Koda Health, Houston, uses AI to help guide difficult conversations in health care, starting with end-of-life care planning.

"You're entitled to protect the healthcare decisions that matter most to you and your family," the company's website promises. "Koda creates Care Plans to ensure that you get the medical care you want."

Immuno Genesis

Photo via Getty Images

Houston-based ImmunoGenesis is a clinical-stage biotechnology company developing therapeutics to catalyze effective immune responses in immunologically "cold" cancers such as prostate, colorectal, and pancreatic.

"Compared to existing immunotherapy drugs, we believe this antibody will both provide more consistent benefit for patients with immune-infiltrated tumors, and, for the first time, will also benefit patients with immune 'cold' cancers," says founder Dr. Michael A. Curran in a press release announcing the company's grant from the Cancer Prevention and Research Institute of Texas.

Ictero Medical

Image via Getty Images

Ictero Medical, based in Houston, is developing the first minimally invasive cryoablation solution to treat patients with gallstone disease. Ictero Medical has created a minimally invasive treatment, called The CholeSafe System, that uses cryoablation to defunctionize the gallbladder without having to remove it.

gBETA has announced its second Houston cohort. Photo courtesy of gBETA

Early-stage startup accelerator names latest Houston cohort

ready cohort 2

An early-stage startup accelerator with a national presence has announced its latest cohorts across the country. Five Houston companies have been named to the local class.

The accelerator, gBETA, is a part of Madison, Wisconsin-based gener8tor's suite of accelerators, and announced its plan to launch in Houston in September 2019. The program's inaugural cohort premiered in May and conducted the first program this summer completely virtually.

This week, gBETA named 50 startups across 10 cohorts to its fall program. Here are the five startups selected from Houston:

  • DOSS: Launched in April, DOSS uses artificial intelligence and data aggregation in the homebuying process.
  • Camelia Alise: The company creates gender-neutral skincare products to treat pseudo-folliculitis condition and has developed a specific spa curriculum for aspiring spa owners and specialists.
  • CaseCTRL: A management platform for surgeons, CaseCTRL's software-as-a-service technology uses AI and logistics to lower operational costs and simplify surgical planning.
  • Melanoid Exchange: An online platform, Melanoid Exchange is giving small minority businesses the opportunity to grow their business through eCommerce.
  • ScalaMed: The company has developed a smart prescriptions platform that provides care teams real-time information on their patients' drug management, and patients with an empowering tool that helps them take control over the prescription process.

The no-cost, equity-free program will last seven weeks and kicked off on October 1. While the program will continue to be virtual, gBETA's operations are located in Amegy Bank's Downtown Launchpad along with Impact Hub Houston and MassChallenge Texas.

"Over the past year, Central Houston has focused on establishing Downtown as a vibrant innovative center of gravity for technology and entrepreneurship in the northern node of the Houston Innovation Corridor," says Robert Pieroni, director of economic development at Central Houston, a gBETA Houston sponsor, in the news release.

"The result has been recruiting nationally-acclaimed accelerator programs, such as gener8tor, to our city and creating Downtown Launchpad, an inclusive village that offers a framework of resources for these programs and the startups and entrepreneurs involved as they seamlessly navigate through the stages of startup production. We're thrilled that gener8tor is one of Downtown Launchpad's resident partners and look forward to the impact created by the startups in the fall cohort."

gBETA Houston's Virtual Pitch Night will be held on Wednesday, Nov. 18, at 5 pm. For more information and to RSVP, click here.

gBETA kicked off its 2020 fall accelerator virtually. Photo courtesy of gBETA

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Innovative Houston urban farm scores national award for green work

to the moon

A Houston urban farm has earned national recognition for its innovative approach to water conservation. Moonflower Farms won the American Heart Association's Foodscape Innovation Excellence Award, which recognizes positive changes in the foodscape, a term for all of the places where food is produced, purchased, or consumed.

The Heart Association selected Moonflower's submission, titled "Sustainable Farming Through Water Conservation," from 26 entries. Dallas' Restorative Farms earns the Foodscape Innovation Consumer Choice Award.

"These two innovations demonstrate a way of producing food that promotes affordability and equitable access, and the American Heart Association is proud to recognize these efforts," AHA chief medical officer for prevention Eduardo Sanchez said in a release.

Located in a 20,000-square-foot greenhouse south of downtown, Moonflower operates what it describes as Houston's first vertical indoor farm. The method both reduces the amount of space needed to grow the farm's microgreens, lettuces, herbs and edible flowers and it eliminates the disruptions caused by adverse weather conditions, which allows the farm to produce year round.

Moonflower uses a closed-loop system for capturing rainwater to feed its crops. The water is treated and oxygenated so that it can be reused. Not having to pay for water from the City of Houston allows the farm to operate more economically and sell its produce at an affordable price to restaurants and individuals.

"Our hydroponic farm uses 90-percent less water than conventional farms," Moonflower founder and CEO Federico Marques said in a statement. "We provide year-round produce to residents in historically underserved communities and donate produce to local charitable food systems."

One of those charities is Houston non-profit Second Servings, which "rescues" food from restaurants and events and distributes it to food pantries and other resources.

"The donations we receive from Moonflower Farms are incredible," Second Servings founder and president Barbara Bronstein said. "Their hydroponically grown greens are so appreciated by the needy Houstonians we serve, who lack affordable, convenient access to fresh produce."

Recently, Moonflower introduced a SupaGreens subscription box that allows customers to purchase greens weekly, bimonthly, or monthly. The box is delivered directly to consumers.

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This article originally ran on CultureMap.

Houston blockchain startup to collaborate to increase supply chain transparency

impact shopping

More than two-thirds of the country's consumers have been reported saying that a business's social reputation will influence their buying decisions. A Houston blockchain startup has teamed up with another company to increase transparency.

Topl and Denver-based TrackX, a software-as-a-service asset management and supply chain solution provider, have entered into a partnership aimed at combining technology to create a verifiable tracking and tracing solution to equip company supply chains with sustainability, transparency, and efficiency.

According to Topl CEO, Kim Raath, the FDA announced new requirements in September, and the new rule requires full traceability in several agri-food products.

"This new rule will force many agri-food brands to take a deep look across their supply chains and find a way to track and trace their products," says Raath in a press release. "Topl and TrackX's solution will be a great option for these companies having to comply with new regulations and compliance mandates. Further, our joint solution allows users to visualize their supply chain data, monitor suppliers, and easily report the progress of ESG initiatives to all stakeholders."

Kim Raath is the CEO of Topl. Photo courtesy of Topl

Together with Topl's purpose-built blockchain technology and TrackX's core enterprise asset management and supply chain optimization capabilities, companies can securely share verified event data to lower costs and increase transparency.

"Our clients have a unique opportunity to turn supply chain optimization into a competitive advantage," says Tim Harvie, TrackX CEO, in the release. "TrackX already automates supply chain execution and analytics for many leading brands and retailers.

"Tight integration with Topl's blockchain will now provide the 'proof' to all supply chain stakeholders that certain events have occurred," he continues. "In partnership with Topl, our enterprise customers will have the tracing, tracking, visibility and accountability they need to meet their digital supply chain and ESG initiatives."

Houston energy expert on how big data yields more reliable results

Guest column

Abraham Maslow's hierarchy of need tells us that at our core, humans crave safety and sustenance. When you turn on the light each morning while getting ready for work, or when you check your bank account and see your paycheck arrived on schedule, we expect every aspect of our daily lives to work.

In today's world, we often take these things for granted, until reliability is threatened. Our dependency is revealed in the frenzy over a potential toilet paper shortage and in the panic buying of gasoline in a hurricane. When things in society are consistent, economies thrive. However, when you introduce fear and uncertainty, things begin to spiral. It is in these times that the decisions we make can have the biggest impact on the world around us.

The link between impactful decisions and reliability has brought our society to a pivotal moment in history. We have created a society so reliable and developed that even during the coronavirus lockdown, the basic needs of Americans could be met with only 25 percent of our workforce actively working. By increasing productivity using machines and systems, we have been able to improve our overall quality of life, but not without a price. As a result of such high improvement, we as a society have come to not only expect, but demand, reliability at all times.

When dependability waivers and anxiety rises, those in key decision-making positions are faced with unprecedented situations. Due to distress and a lack of understanding of certain situations, those in decision making positions are often times forced to make decisions based on rapid response and emotion. Because of this, consistency and reliability suffer.

A prime example of an emotional response is the coronavirus shutdown that occurred earlier this year. As a response to the growing fear and panic over the virus, major portions of our economy were shut down; schools were closed; and citizens were confined to their homes.

What followed was the bankruptcy of thousands of businesses, an unprecedented wave of fear throughout society and a disruption to the consistency of our daily lives. We have yet to know what lasting impacts this decision will have on our future economy or livelihood, but we now understand that rapid decision making is often met with long-term consequences.

While there will continue to be disagreements on all sides regarding the handling of the shutdown, what is undisputable is that we as a society have gained an opportunity to learn. We now have the unique advantage of using data in ways that has never been used before in order to make consistently better decisions, allowing us the opportunity to perform at levels we have never thought possible.

Whether it be data advancements in sports (think Billy Beane and the Oakland Athletics), or the progression of technology (continuous iPhone updates), we are able to study the improvements of data on society in order to make more reliable decisions. With more powerful data analytics and innovations in data sciences, we are able to positively impact the most vital components of our society in order to make decisions that will drive evolution and reliability.

As the world continues to progress, the decisions we are forced to make have become more complex. With each complicated decision comes the potential for lasting positive or negative impact on society. In shifting from emotional, rapid reactions towards more data and quantitative focused methods, we have the unique and unprecedented opportunity to make our world a more reliable, stable and creative place.

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Ryan Sitton is the founder of Pinnacle and the author of "Crucial Decisions."