NanoTech Materials celebrated its move into a new facility — a 43,000-square-foot space in Katy, Texas, this week. Photo courtesy of NanoTech Materials

A Houston startup has moved into a new space that's more than four times larger than its previous setup — a move that's setting the company up to scale its business.

NanoTech Materials celebrated its move into a new facility — a 43,000-square-foot space in Katy, Texas, this week. The materials science company currently distributes a roof coating that features its novel heat-control technology across the company. Originally founded in a garage, the company has now moved from its 10,000-square-foot space at Halliburton Labs into the larger location to support its growth.

“The new facility allows us to not just focus on the roofing, and that’s growing at a pretty rapid pace, but also stand up different production lines for our next iteration of technologies coming-out," Mike Francis, co-founder and CEO of NanoTech tells InnovationMap.

The space allows for a 340 percent increase in the manufacturing and operational capabilities, including producing 55 million square feet a year of roof coating. Francis says the new products he's focused on launching and scaling include a wildfire protectant coating and liquid applied insulation for trucks and containers to control heat for driver and worker safety.

Francis adds that he will be expanding the company's team to support this growth.

“We’re constantly hiring now,” he says. “We have about 25 employees right now. Next year, we’ll probably be double that. We’re kind of in a hypergrowth phase."

Francis likes to credit Houston in part for NanoTech's ability to grow at this pace and to be successful.

Mike Francis is the CEO and co-founder of NanoTech Materials. Photo via LinkedIn

“Houston has a shot at being one of the top startup cities of the world — I think it’s going to take a lot of time and capital, but what makes Houston different is its ability to scale existing technologies,” Francis says.

“I really think that Houston is already the spot to take an existing technology and build a team around it to turn it into a company because you have all of the players — whether it’s the end customer or the incubators and 'scalerators' — and you have all of these pieces coming into place," he continues. "Maybe it’s not the best place to start a company, but it’s definitely the best place to scale a company because of the ecosystem is really willing to participate and raise up startups like ours."

As the first company selected for Halliburton's incubator, Halliburton Labs, when it launched in 2020, NanoTech has worked closely with the company that housed and supported them for years.

“Once you’re in the Halliburton Labs fold, they are always just a phone call away from making something happen," he says. “We’re transferring all that knowledge into a bigger facility — growing up and graduating from what they gave us.”

Last year, NanoTech raised an oversubscribed funding round that brought on a handful of new investors. The details of the round were not disclosed, but NanoTech did release that the round included participation from three institutional investors, two corporate-strategic investors, and seven family offices. The company originally raised its seed round in 2020.

The NanoTech team, including Francis and Carrie Horazeck, chief commercial officer, joined the Houston Innovators Podcast last year to discuss how they've rolled out their first line of business.


The ultimate who's who of 2023 — these are our favorite Houston Innovators Podcast guests of last year. Photos courtesy

Editor's Picks: 7 favorite Houston Innovator Podcast episodes of 2023

year in review

Editor's note: In 2023, I recorded 50 episodes of the Houston Innovators Podcast — a weekly discussion with a Houston innovator, startup founder, investor, and more. I've rounded up seven podcast episodes that stood out for me looking back at the year of recordings. Scroll through to see whom I selected and stream their individual episodes, and tune into the last episode of the year where I explain why I enjoyed each conversation.



Episode 174 - Rolling out nationwide - Mike Francis and Carrie Horazeck of NanoTech

NanoTech's Chief Commercial Officer Carrie Horazeck and Co-Founder and CEO Mike Francis join the Houston Innovators Podcast to celebrate the nationwide launch of their roof coating product. Photo via LinkedIn

A Houston startup is celebrating its nationwide launch of its flagship product that coats roofs to reduce energy waste.

NanoTech's Nano Shield Cool Roof Coat is a unique product that can be added onto roofs to reduce energy waste on buildings. Co-founder and CEO Mike Francis and Chief Commercial Officer Carrie Horazeck joined the Houston Innovators Podcast to share more details about the product.

"It's just a coating that can go on top of existing structure — any type of commercial roof," Horazeck says on the show. "We have a pretty good amount of data from 2022 showcasing that we can reduce HVAC consumption within the building by about 30 to 40 percent.

"Our clients really see a immediate benefit in their energy bill, and, of course, if you reduce the HVAC consumption, that automatically translates to a decrease in your scope one emissions," she continues. Continue reading.


Episode 181 - Gearing up for high-speed global travel - Sassie Duggleby of Venus Aerospace

Sarah "Sassie" Duggleby of Venus Aerospace joins the Houston Innovators Podcast this week. Photo courtesy of Venus

Sarah "Sassie" Duggleby is on a mission to get people home in time for dinner — whether they are traveling around the world or working for her business. That's why she founded Venus Aerospace, which is developing hypersonic space planes. It's also why she relocated the company from the West Coast to Houston.

"We knew we had to find a location where we could test our engine and still be home for dinner," Duggleby says on this week's episode of the Houston Innovators Podcast. "Our company vision is 'home for dinner.' We want to fly you across the globe and have you home for dinner. And, if you work for us, we want you home for dinner."

Venus's technology enables this revolutionary travel through its supersonic combustion engine — more akin to a rocket's engine than an airplane's — that allows for travel at a higher elevation, she explains on the show. Jet engines rely on air outside of the aircraft to combust, and rocket engines work with a system that supplies air internally. And, as Duggleby explains, the engine can go further with the same amount of fuel, so it's a more sustainable way of traveling too. Continue reading.


Episode 182 - Stopping neurodegenerative diseases in their tracks - Howard Berman of Coya Therapeutics

For Howard Berman, CEO and co-founder of Coya Therapeutics, commercializing his company is personal. Photo courtesy of Coya

When Howard Berman sought out renowned Houston Methodist researcher and neurologist Dr. Stanley Appel, he was looking for treatment for his father, who was suffering from dementia. He wasn't looking for a job, but Dr. Appel had other ideas and asked Berman to meet with him.

"I was interested in what I could do for my dad," Berman says on the Houston Innovators Podcast, explaining how he took the meeting with Dr. Appel, who then presented him with some of his research. "By slide five my jaw had hit the ground.

"He had shown that he could stop the progression in one of his early trials of ALS," Berman says.

Not too long after that meeting, Berman, who founded digital health platform imaware, joined Dr. Appel to lead commercialization of Coya Therapeutics, a biotech startup that raised over $20 million in venture funding before going public a few months ago. Continue reading.


Episode 187 - Bridging the gap to innovation - Ramanan Krishnamoorti of University of Houston

Ramanan Krishnamoorti, vice president of energy and innovation at the University of Houston, joins the Houston Innovators Podcast to talk about the university's dedication to helping the city become an innovative force. Photo via UH.edu

Ramanan Krishnamoorti has had a varied career in academia, from an engineering professor to nanotech research. While he never made the transition from researcher to entrepreneur, he managed to snag a CEO title at the university about a decade ago: Chief energy officer.

Since then his role has expanded to include advancing UH's innovation of all kinds — from health tech to the arts — as vice president of energy and innovation at UH. In his role, he oversees the UH Technology Bridge, a lab and coworking space for tenants just a short drive away from UH's main campus, as well as future plans, like a new central campus hub for innovation that's in its early stages of development.

"What we really need at the university today is to bring innovation — which tech transfer is a piece of — and connect that to real-world challenges to deliver what the world needs, which is talented folks delivering new innovative, entrepreneurial, or intrapreneurial programs," Krishnamoorti says on this week's episode of the Houston Innovators Podcast. Continue reading.

Episode 193 - Innovating in the East End - Erik Ibarra of Magnolia Fund and ORDRS

Erik Ibarra's latest venture is to give agency to residents in the neighborhood he grew up in. Photo courtesy

Innovation isn't always tinkering with tech or programming software, although serial entrepreneur Erik Ibarra knows that world well. Sometimes it's about rethinking how a community improves and develops without doing the residents a disservice.

That's why Ibarra started Magnolia Fund, a mission-driven investment fund dedicated to enriching the East End community and preserving the neighborhood's culture and history. Ibarra, who has lived in the area the majority of his life, says on the Houston Innovators Podcast, that he's looking to turn residents into investors.

"Our investors from the neighborhood, today they walk around and look at their house and say, 'I own that,' and that's great," Ibarra says. "In the future, our investors should be able to say that, and then point to a building and say, 'I own a portion of that building too. And I helped that small business over there.'" Continue reading.


Episode 198 - The undeniable impact of AI - Anshumali Shrivastava of ThirdAI CorpEpisode 198 - The undeniable impact of AI - Anshumali Shrivastava of ThirdAI Corp

Anshumali Shrivastava joins the Houston Innovators Podcast to share the revolutionary work ThirdAI is doing for artificial intelligence. Photo via rice.edu

Anshumali Shrivastava's career has evolved alongside the rise of artificial intelligence. Now, he believes his company represents the future of the industry's widespread implementation.

Shrivastava, who's also a professor at Rice University, founded ThirdAI, pronounced "third eye," in 2021 to democratize artificial intelligence through software innovations. As Shrivastava explains on the Houston Innovators Podcast, AI processes have historically been run on larger, less accessible computing hardware. ThirdAI's tools are able to run on a regular central processing unit, or CPU, rather than the more powerful graphics processing unit, or GPU.

"We focus on the problems that people are facing in the current AI ecosystem," Shrivastava says on the podcast. "Right now, if you are to build some of the large-language models and (linear programming) models, you need a lot of computing power, dedicated engineers to move it, and, even if you are using fully managed services, it's costly and there are a lot of privacy implications because you have to move data around." Continue reading.


Episode 212 - The 'frivolous' lawsuit over DEI funding - Carolyn Rodz and Elizabeth Gore of Hello Alice

Hello Alice Co-Founders Carolyn Rodz and Elizabeth Gore join the Houston Innovators Podcast to discuss the lawsuit they're facing. Photo courtesy Cayce Clifford/Hello Alice

For years, Hello Alice has been helping small businesses across the country get equitable access to funding and support. Now, the Houston tech company is facing its own obstacle: An affirmative action lawsuit.

"I don't think in a million years that we ever expected anything like this," Elizabeth Gore, co-founder and president of Hello Alice, says on the Houston Innovators Podcast. "There's surprise, then there's fear, and then there's anger. But now on the other side of it, we're emboldened, confident, and more passionate than ever."

America First Legal's lawsuit against Hello Alice and its partner, Progressive Insurance, alleges that their program to award10 $25,000 grants to Black-owned small businesses constitutes racial discrimination. AFL was founded by former Trump Administration adviser Stephen Miller and features a handful of other former White House officials on its board. Continue reading.

NanoTech closed an oversubscribed round of funding, the company announced this week. Photo courtesy of NanoTech

Houston climate-tech startup adds new investors in oversubscribed funding round

cap table additions

A Houston startup that has developed an innovative coating material that can reduce energy consumption has raised fresh funding for its cross-country expansion.

NanoTech Inc. announced its latest funding news — an oversubscribed funding round that brings onboard a handful of new investors. The details of the round were not disclosed, but NanoTech did release that the round included participation from three institutional investors, two corporate-strategic investors, and seven family offices. These entities join initial investor, Austin-based Ecliptic Capital.

NanoTech's flagship product is a waterproof thermal coating, called the Nano Shield Cool Roof Coat, which began rolling out across the country this year. Not only does the product reduce energy costs for the building owner, but it reduces emissions as well.

"It's crucial to recalibrate the sustainability narrative – environmental responsibility and financial return can go hand in hand," says Mike Francis, CEO and co-founder of NanoTech, in a news release. “We’ve transformed the roof from a cost center to a savings source by reducing energy expenditures while also significantly shrinking the building's carbon footprint.”

"The substantial decline in CO2 emissions and energy costs resulting from reduced reliance on HVAC systems is far more than a fringe benefit — it forms the cornerstone of our long-term strategy to lead the climate-resilient materials market. Beyond corporate objectives, it's a personal source of immense pride to foster a healthier planet for generations to come," Francis continues.

As the first selected company in Houston-based Halliburton Labs, NanoTech continues to benefit from the incubator's industrial scaling resources. Francis and Chief Commercial Officer Carrie Horazeck recently joined the Houston Innovators Podcast to discuss the impact their product is making as they roll out nationwide.

"It's just a coating that can go on top of existing structure — any type of commercial roof," Horazeck says on the show. "We have a pretty good amount of data from 2022 showcasing that we can reduce HVAC consumption within the building by about 30 to 40 percent.

"Our clients really see a immediate benefit in their energy bill, and, of course, if you reduce the HVAC consumption, that automatically translates to a decrease in your scope one emissions," she continues.


NanoTech's Chief Commercial Officer Carrie Horazeck and Co-Founder and CEO Mike Francis join the Houston Innovators Podcast to celebrate the nationwide launch of their roof coating product. Photo via LinkedIn

Houston material science company strategically rolls out flagship product nationwide

houston innovators podcast episode 174

A Houston startup is celebrating its nationwide launch of its flagship product that coats roofs to reduce energy waste.

NanoTech's Nano Shield Cool Roof Coat is a unique product that can be added onto roofs to reduce energy waste on buildings. Co-founder and CEO Mike Francis and Chief Commercial Officer Carrie Horazeck joined the Houston Innovators Podcast to share more details about the product.

"It's just a coating that can go on top of existing structure — any type of commercial roof," Horazeck says on the show. "We have a pretty good amount of data from 2022 showcasing that we can reduce HVAC consumption within the building by about 30 to 40 percent.

"Our clients really see a immediate benefit in their energy bill, and, of course, if you reduce the HVAC consumption, that automatically translates to a decrease in your scope one emissions," she continues.

Now, NanoTech is playing in the climatetech materials space, the duo explains, and is able to offer clients the opportunity of sustainability with a return — and provide the data for them to prove it.

When deciding how to roll out the product nationally, Francis and Horazeck decided to create a partner enablement program of around 20 companies rather than going with one big distributor.

"We wanted to make sure we developed really strong relationships with our partners and brought on partners that really believed in our vision and understood what we're trying to do at NanoTech — not just with the roof coating, but the whole vision of our company," Horazecks says, explaining that NanoTech has 12 partner companies already and is actively interviewing for the last eight spots.

The roof coating is just the beginning, Francis and Horazeck say about the growing company. NanoTech, which also has a fireproofing product that can protect against fires of up to 1,800 degree Celcius temperatures, also is working on a clear coating product for windows and even solar panels.

"We have the technologies — we're filing multiple patents almost every month to enter different areas of the green building and fireproofing spaces. We're working with more than 40 Fortune 500 companies — things are really clicking," Francis says on the show. "What I think is the next period in our company history is hiring the best talent we can possibly find."

Francis and Horazeck share more about the future of NanoTech on the podcast, and each share their thoughts on the vast opportunities in Houston's networking community and innovation ecosystem. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


Here's your latest roundup of Houston innovation news you may have missed. Photo by Tim Leviston/Getty Images

Houston startup names new exec, innovators join prestigious program, and more news

short stories

Houston's cooling down, but the city's innovation news is heating up, and there might be some headlines you may have missed.

In this roundup of short stories within Houston startups and tech, a Houston startup has a new C-level exec, two innovators join a international cohort of leaders, and more.

NanoTech names new chief commercial officer

Carrie Horazeck is now the chief commercial officer for NanoTech. Photo courtesy of NanoTech

Houston-based materials science company NanoTech Inc. has appointed Carrie Horazeck as chief commercial officer for the startup, which created a fireproofing and carbon reduction through cool roof coatings. In her new role, Horazeck will lead marketing and sales strategy for the growing company.

“I’ve been a fan of NanoTech since I first met co-founder and CEO Mike Francis at a Halliburton Labs event last year," Horazeck says in a statement. “It’s an incredible team, with an incredible product. They are on the precipice of major growth and I’m very honored to be a part of that journey.”

Prior to NanoTech, Horazeck spent 11 years in management consulting helping to grow her clients' businesses, staying tuned into consumer trends and behaviors to guide product development and intelligent marketing strategy. She's worked with a wide range of industries and clients including Samsung, General Mills, Newell Brands, Coca-Cola, Unilever, American Express, British American Tobacco, Anheuser-Busch, and the Department of Education in New York City. Most recently, she led commercial development and market penetration strategy for an Austin based startup in the renewable energy space.

"We are excited to have Carrie join the NanoTech team. She is going to help us get one step closer to our goal of reducing carbon emissions with our cool roof coating and fireproofing critical infrastructure," says Francis in the statement.

2 Houstonians named to global cohort

Houstonians Allie Danziger and Natasha McDaniel were announced to be joining the Fall 2022 Milestone Makers cohort. Photos courtesy

Two Houston innovators have been named to Nasdaq Entrepreneurial Center's Fall 2022 Milestone Makers cohort, which selects individuals addressing the United Nation's Sustainable Development Goals.

The virtual, 12-week program provides individualized mentorship and executive coaching, as well as access to the Center’s vast network of industry experts to help each founder with his or her milestone. The new cohort was selected through application process, and all hope to improve the lives of and support communities across the globe. The two Houstonians in the current cohort include:

  • Allie Danziger of Ampersand, which enhances employee retention by ensuring mastery in key skills required for entry-level professionals.
  • Natasha McDaniel of Lit for Life, which offers culturally relevant reading and writing resources as well as family coaching and educational consulting services.

Applications are open for the Winter 2023 program are now open.

Houston robotics company to ring the bell on Wall Street

The Nasdaq Bell Ringing Ceremony for Nauticus Robotics, Inc. will take place this Thursday. Image via LinkedIn

Houston-based Nauticus Robotics, which went public last month via SPAC, is due to ring the Nasdaq bell on Wall Street.

The company, which now trades under the $KITT ticker, will have its bell ringing ceremony beginning at 2:45 p.m. CT on October 20 and can be viewed via this link.

Nauticus continues to be led by CEO Nicolaus Radford and the current executive team.

“The closing of this business combination represents a pivotal milestone in our company’s history as we take public our pursuit of transforming the ocean robotics industry with autonomous systems,” Radford, who founded what was known as Houston Mechatronics in 2014, said in a news release about the IPO. “Not only is the ocean a tremendous economic engine, but it is also the epicenter for building a sustainable future.”

UH named 2022 Hispanic Serving Institution Leader by U.S. Fulbright program

UH — and its students — have been recognized by the Fulbright organization. Photo courtesy of UH

For the second year in a row, the University of Houston has been named as a 2022 Fulbright Hispanic Serving Institution Leader.

“As the state’s premier Hispanic-Serving Institution and a top Fulbright producer, the University of Houston strives to ensure an environment of inclusion and success for all,” said UH President Renu Khator. “This recognition is yet another milestone that reinforces what so many already know about our institution … that our students are supported both culturally and academically.”

The recognition was announced the Hispanic Association of Colleges and Universities annual conference in San Diego on Oct. 10.

The University of Houston recently announced 10 student Fulbright recipients, each prepared to travel far and wide to gain international insights, according to the news release. Since 2018, nearly 50 Fulbright scholarships have been awarded to UH students.

“Enhancing learning and research experiences for students and faculty through the Fulbright Program is important to expanding the University’s international footprint,” says Michael Pelletier, executive director of UH’s Institute for Global Engagement in the release.

Texas investor named among outstanding women in clean energy

Phoebe Wang was honored for her work at Shell Ventures. Photo via LinkedIn

The U.S. Department of Energy recently announced the nine winners of the 2022 Clean Energy Education & Empowerment Awards that honors women for outstanding leadership and accomplishments in clean energy.

“For too long, there has been a significant gender gap in the energy sector, meaning half the population have had a minimized impact on one of our most important industries,” says U.S. Secretary of Energy Jennifer M. Granholm in a news release. “As we transition to a clean energy economy, we will have to tap into the pool of amazing women working in energy and grow their ranks. That’s why DOE is proud to recognize the winners of this year’s C3E Awards, a diverse group of changemaking women tackling some of the biggest challenges in energy.”

Among the honorees, Phoebe Wang, formerly of Shell Ventures and based in Texas, was recognized in the business category. Wang "leads investments in early- and late-stage startups working on technologies to accelerate the energy transition in the areas of hydrogen, carbon capture utilization and storage, energy storage, mobility, and power," per the release. In the past decade, she has invested more than $150 million startups and has been closely involved in the Rice Alliance for Technology and Entrepreneurship. Last week, Wang was announced to be joining the Amazon Climate Pledge Fund as investment partner.

Now in its 11th year, the C3E Inititive led by the DOE — in collaboration with the MIT Energy Initiative, Stanford University’s Precourt Institute for Energy, and the Texas A&M Energy Institute — will award each winner with a cash gift of $8,000 and national recognition of their efforts.

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CultureMap Emails are Awesome

Big winners: 5 Houston companies that raised the most funding in 2024

year in review

Editor's note: As 2024 comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. When it came to the money raised in Houston, these five startups raised the most, according to reporting done by InnovationMap. Be sure to click on each story to read the full article.

Fervo Energy secures $600M in multiple rounds

The latest deal brings Fervo's total funding secured this year to around $600 million. Photo courtesy of Fervo

Fervo secured a lot of fresh funding this year to deliver on its 100x growth plans. Most recently, the company announced that it has raised $255 million in new funding and capital availability. A $135 million corporate equity round was led by Capricorn’s Technology Impact Fund II and a $120 million letter of credit and term loan facility was granted by Mercuria, an independent energy and commodity group that previously invested in the company. Read more about the round.

In February, Fervo secured $244 million in a financing round led by Devon Energy, and in September, the company received a $100 million bridge loan for the first phase of its ongoing project in Utah. This project, known as Project Cape, represents a 100x growth opportunity for Fervo, as Latimer explained to InnovationMap earlier this year. As of now, Project Cape is fully permitted up to 2 GW and will begin generating electricity in 2026, per the company.

Solugen scores $213.6M to support new facility

The new Solugen facility is expected to reduce annual carbon emissions by up to 18 million kilograms. Photo courtesy of Solugen

Houston-based Solugen secured financing from the U.S. Department of Energy's Loan Programs Office in June to support its mission of producing clean chemicals.

The LPO's $213.6 million loan guarantee will go toward the construction of the company's 500,000-square-foot Bioforge Marshall facility in Southwest Minnesota, which broke ground in April and will produce bio-based chemical products to be used in wastewater treatment, construction, agriculture, and the energy sector. According to Solugen, the facility is expected to reduce annual carbon emissions by up to 18 million kilograms.

"American manufacturing is at a turning point, and we are proud to have the opportunity to work with the DOE in bringing critical chemical production capabilities onshore to communities like Marshall," Gaurab Chakrabarti, CEO of Solugen, says in a news release. "By scaling cutting-edge technologies, we are meeting domestic demand for innovative solutions and setting global standards for sustainable biomanufacturing." Read more about the round.

Cart.com brings in $130M in financing, series C extension

Cart.com announced a $25 million series C extension round and $105 million in debt refinancing from investment manager BlackRock. Photo courtesy of Cart.com

While 2024 was less lucrative for Houston-based Cart.com when it comes to VC activity, the scaleup did pull in significant funding.

The company, which operates a multichannel commerce platform, secured $105 million in debt refinancing from investment manager BlackRock in July.

The debt refinancing follows a recent $25 million series C extension round, bringing Cart.com’s series C total to $85 million. The scaleup’s valuation now stands at $1.2 billion, making it one of the few $1 billion-plus “unicorns” in the Houston area. Read more about the round.

Procyrion closes $57.7M series E to fund journey to FDA approval, commercialization

Procyrion has announced the closing of its series E round of funding. Photo via Getty Images

Houston-born and bred medical device company, Procyrion, has completed its series E with a raise of $57.7 million, including the conversion of $10 million of interim financing.

Procyrion is the company behind Aortix, a pump designed to be placed in the descending thoracic aorta of heart failure patients, which has been shown to improve cardiac performance in seriously ill subjects. The money raised will allow the company to proceed with a the DRAIN-HF Study, a pivotal trial that will be used for eventual FDA approval and commercialization.

The Aortix is the brainchild of Houston cardiologist Reynolds Delgado. According to Procyrion’s CSO, Jace Heuring, Delgado, gained some of his experience with devices for the heart working with legendary Texas Heart Institute surgeon O.H. “Bud” Frazier. He filed his first patents related to the Aortix in 2005. Read more about the round.

Utility Global raises $53M series C investment

Utility Global’s technology enables reduction of greenhouse gas emissions along with generation of low-carbon fuels and chemicals. Photo courtesy of Utility Global

Houston-based Utility Global, a maker of decarbonization-focused gas production technology, has raised $53 million in an ongoing series C round.

Among the participants in the round are Canada’s Ontario Power Generation Pension Plan, the XCarb Innovation Fund operated by Luxembourg-based steel company ArcelorMittal, Houston-based investment firm Ara Partners, and Saudi Aramco’s investment arm.

Also, Utility Global and ArcelorMittal have agreed to develop at least one decarbonization facility at an ArcelorMittal steel plant. Read more about the round.

Houston scientists create first profile of Mars’ radiant energy budget, revealing climate insights on Earth

RESEARCH FINDINGS

Scientists at the University of Houston have found a new understanding of climate and weather on Mars.

The study, which was published in a new paper in AGU Advances and will be featured in AGU’s science magazine EOS, generated the first meridional profile of Mars’ radiant energy budget (REB). REB represents the balance or imbalance between absorbed solar energy and emitted thermal energy across latitudes. An energy surplus can lead to global warming, and a deficit results in global cooling, which helps provide insights to Earth's atmospheric processes too. The profile of Mars’ REB influences weather and climate patterns.

The study was led by Larry Guan, a graduate student in the Department of Physics at UH's College of Natural Sciences and Mathematics under the guidance of his advisors Professor Liming Li from the Department of Physics and Professor Xun Jiang from the Department of Earth and Atmospheric Sciences and other planetary scientists. UH graduate students Ellen Creecy and Xinyue Wang, renowned planetary scientists Germán Martínez, Ph.D. (Houston’s Lunar and Planetary Institute), Anthony Toigo, Ph.D. (Johns Hopkins University) and Mark Richardson, Ph.D. (Aeolis Research), and Prof. Agustín Sánchez-Lavega (Universidad del País, Vasco, Spain) and Prof. Yeon Joo Lee (Institute for Basic Science, South Korea) also assisted in the project.

The profile of Mars’ REB is based on long-term observations from orbiting spacecraft. It offers a detailed comparison of Mars’ REB to that of Earth, which has shown differences in the way each planet receives and radiates energy. Earth shows an energy surplus in the tropics and a deficit in the polar regions, while Mars exhibits opposite behavioral patterns.

The surplus is evident in Mars’ southern hemisphere during spring, which plays a role in driving the planet’s atmospheric circulation and triggering the most prominent feature of weather on the planet, global dust storms. The storms can envelop the entire planet, alter the distribution of energy, and provide a dynamic element that affects Mars’ weather patterns and climate.

The research team is currently examining long-term energy imbalances on Mars and how it influences the planet’s climate.

“The REB difference between the two planets is truly fascinating, so continued monitoring will deepen our understanding of Mars’ climate dynamics,” Li says in a news release.

The global-scale energy imbalance on Earth was recently discovered, and it contributes to global warming at a “magnitude comparable to that caused by increasing greenhouse gases,” according to the study. Mars has an environment that differs due to its thinner atmosphere and lack of anthropogenic effects.

“The work in establishing Mars’ first meridional radiant energy budget profile is noteworthy,” Guan adds. “Understanding Earth’s large-scale climate and atmospheric circulation relies heavily on REB profiles, so having one for Mars allows critical climatological comparisons and lays the groundwork for Martian meteorology.”

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This article originally ran on EnergyCapital.

Houston startup secures $22.5M to innovate cell therapy to fight cancer

fresh funding

A promising cell therapy company has raised its latest funding round — to the tune of $22.5 million.

Indapta Therapeutics, which has a dual headquarters in Houston and Seattle, is a clinical stage biotechnology and next-generation cell therapy company focused on the treatment of cancer and autoimmune diseases. The company announced it has closed a $22.5 million round of new financing to accelerate the clinical development of its differentiated allogeneic Natural Killer cell therapy.

"This funding will enable us to generate significant additional data in our ongoing trial of IDP-023 in cancer as well as initial data from our first trial in autoimmune disease," Mark Frohlich, Indapta’s CEO, says in a news release.

Indapta has completed enrollment in the safety run-in portion of the Phase 1 clinical trial of IDP-023 in Non-Hodgkin’s Lymphoma and Multiple Myeloma, according to the company. The patients received up to three doses of IDP-023 without and with interleukin (IL)-2.

Completing the round were current investors RA Capital Management, Bayer's impact investment arm Leaps, Vertex Ventures HC, Pontifax, and the Myeloma Investment Fund, the venture philanthropy subsidiary of the Multiple Myeloma Research Foundation. Earlier in December, Indapta announced a collaboration with Sanofi to explore the combination of its allogeneic g-NK cell therapy IDP-023 with Sanofi’s CD38 that targets the monoclonal antibody, Sarclisa (isatuximab).

"Preliminary results of IDP-023 in cancer are encouraging and we look forward to initiating our Phase 1 trial for multiple sclerosis in Q1 2025,” Frohlich continues. “This financing, together with our recently announced collaboration with Sanofi, highlights the promise of our differentiated platform.”

Also in August, Indapta announced a FDA clearance of its IND of IDP-023 in combination with ocrelizumab in progressive MS.


Mark Frohlich is the CEO of the Houston- and Seattle-based company. Photo courtesy of Indapta Therapeutics