3 Houston organizations announce strategic appointments

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Here are three of the latest updates on new hires and promotions from these Houston organizations. Photos courtesy

It's been a busy year so far for Houston organizations — three of which have made new appointments to their leadership.

In this round up of movers and shakers in Houston innovation, a venture capital firm names its newest principal, an astronaut gets a leadership role here at ground control, and a VR studio snags a leader to steer its growth.

Joe Acaba, chief of NASA's Astronaut Office at Johnson Space Center

Joe Acaba was promoted to a new role and will be responsible for crew assignments for future spaceflight missions. Photo via NASA

NASA tapped Joe Acaba as its chief of the Astronaut Office based in Johnson Space Center in Houston. He's served on multiple spaceflights and is a former U.S. Marine and former educator. According to NASA, he's the first person of Hispanic heritage selected to lead the office.

Acaba replaces Drew Feustel, who spent two years as deputy chief and has been acting chief of the office since NASA astronaut Reid Wiseman left the post late last year.

"Joe is an experienced space flyer and a proven leader, and he will undoubtedly inspire the next generation of NASA astronauts," says NASA Administrator Bill Nelson in a news release. " As we build on the International Space Station’s unparalleled success in low-Earth orbit with our eyes on the Moon and then Mars, Joe will play an integral role in ensuring our NASA astronauts are prepared for the challenges ahead."

Acaba, who spent a total of 306 days in space, has already supported the astronaut office in a few of roles, including director of operations in Russia and chief of the Vehicle Integration Test Office. In this new role, he will be oversee astronaut resources and operations and help develop astronaut flight crew operation concepts. Additionally, Acaba will make crew assignments for future spaceflight missions, including astronauts assigned to fly on Artemis missions.

“Our Johnson Space Center team congratulates Joe Acaba on his selection to chief of the Astronaut Office. We wish him well as he takes on this new and exciting leadership role,” says NASA Johnson Space Center Director Vanessa Wyche.

Samantha Lewis, partner at Mercury Fund

Samantha Lewis was promoted to partner at Mercury Fund. Photo courtesy of Mercury Fund

Samantha Lewis was promoted to partner from principal at Houston-based venture capital firm Mercury, per her LinkedIn. She previously was the investment director of investor network GOOSE Capital before joining the Mercury team just over two years ago.

Last year, Lewis — who also served on the board of two Houston-founded startups, Syzygy and Topl — was named a member of the Class 27 of the Kauffman Fellows Program, a group of global innovation investors.

Lewis is focused on what she calls the "power theme" at Mercury, which includes fintech, blockchain, web3, and more. She told InnovationMap on a recent episode of the Houston Innovators Podcast that these industries have been hit in particular within market uncertainty.

Bob Kleinhample, senior vice president of growth at HTX Labs

Bob Kleinhample joins HTX Labs at a time of strategic growth. Photo courtesy of HTX Labs

Virtual reality studio HTX Labs has named Bob Kleinhample as the company’s senior vice president of growth. He has more than 15 years leading business efforts in the tech space. A 20-year Army veteran, Kleinhample will oversee all aspects of HTX Labs' growth — including business development, product strategy, and marketing.

“Bob brings the right balance of market knowledge and product strategy, in combination with the commitment to bring immersive training and simulation to the warfighter, to really drive our EMPACT offering into the market,” says Scott Schneider, CEO and co-founder of HTX Labs. "We’re very excited to be adding this incredibly important role to our organization and having Bob lead these efforts as we expand the usage and adoption of EMPACT across the Department of Defense."

The appointment comes after the startup raised $3.2 million in its first outside capital round.

“Last year we secured funding from Cypress Growth Capital for the sole purpose of accelerating the growth of our EMPACT platform and our customer base, and we immediately began a search for the right person to lead these growth efforts," Schneider continues. "After performing an extensive search, we are fortunate to have connected with Bob Kleinhample who is coming on board to lead our company’s growth efforts“.

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Autonomous truck company rolls out driverless Houston-Dallas route

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Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

Elon Musk's SpaceX site officially becomes the city of Starbase, Texas

Starbase, Texas

The South Texas home of Elon Musk’s SpaceX rocket company is now an official city with a galactic name: Starbase.

A vote Saturday, May 3, to formally organize Starbase as a city was approved by a lopsided margin among the small group of voters who live there and are mostly Musk’s employees at SpaceX. With all the votes in, the tally was 212 in favor to 6 against, according to results published online by the Cameron County Elections Department.

Musk celebrated in a post on his social platform, X, saying it is “now a real city!”

Starbase is the facility and launch site for the SpaceX rocket program that is under contract with the Department of Defense and NASA that hopes to send astronauts back to the moon and someday to Mars.

Musk first floated the idea of Starbase in 2021 and approval of the new city was all but certain. Of the 283 eligible voters in the area, most are believed to be Starbase workers.

The election victory was personal for Musk. The billionaire’s popularity has diminished since he became the chain-saw-wielding public face of President Donald Trump’s federal job and spending cuts, and profits at his Tesla car company have plummeted.

SpaceX has generally drawn widespread support from local officials for its jobs and investment in the area.

But the creation of an official company town has also drawn critics who worry it will expand Musk’s personal control over the area, with potential authority to close a popular beach and state park for launches.

Companion efforts to the city vote include bills in the state Legislature to shift that authority from the county to the new town’s mayor and city council.

All these measures come as SpaceX is asking federal authorities for permission to increase the number of South Texas launches from five to 25 a year.

The city at the southern tip of Texas near the Mexico border is only about 1.5 square miles (3.9 square kilometers), crisscrossed by a few roads and dappled with airstream trailers and modest midcentury homes.

SpaceX officials have said little about exactly why they want a company town and did not respond to emailed requests for comment.

“We need the ability to grow Starbase as a community,” Starbase General Manager Kathryn Lueders wrote to local officials in 2024 with the request to get the city issue on the ballot.

The letter said the company already manages roads and utilities, as well as “the provisions of schooling and medical care” for those living on the property.

SpaceX officials have told lawmakers that granting the city authority to close the beach would streamline launch operations. SpaceX rocket launches and engine tests, and even just moving certain equipment around the launch base, requires the closure of a local highway and access to Boca Chica State Park and Boca Chica Beach.

Critics say beach closure authority should stay with the county government, which represents a broader population that uses the beach and park. Cameron County Judge Eddie Trevino, Jr. has said the county has worked well with SpaceX and there is no need for change.

Another proposed bill would make it a Class B misdemeanor with up to 180 days in jail if someone doesn’t comply with an order to evacuate the beach.

The South Texas Environmental Justice Network, which has organized protests against the city vote and the beach access issue, held another demonstration Saturday that attracted dozens of people.

Josette Hinojosa, whose young daughter was building a sandcastle nearby, said she was taking part to try to ensure continued access to a beach her family has enjoyed for generations.

With SpaceX, Hinojosa said, “Some days it’s closed, and some days you get turned away."

Organizer Christopher Basaldú, a member of the Carrizo/Comecrudo Nation of Texas tribe, said his ancestors have long been in the area, where the Rio Grande meets the Gulf.

“It’s not just important,” he said, “it’s sacred.”

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