3 Houston organizations announce strategic appointments

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Here are three of the latest updates on new hires and promotions from these Houston organizations. Photos courtesy

It's been a busy year so far for Houston organizations — three of which have made new appointments to their leadership.

In this round up of movers and shakers in Houston innovation, a venture capital firm names its newest principal, an astronaut gets a leadership role here at ground control, and a VR studio snags a leader to steer its growth.

Joe Acaba, chief of NASA's Astronaut Office at Johnson Space Center

Joe Acaba was promoted to a new role and will be responsible for crew assignments for future spaceflight missions. Photo via NASA

NASA tapped Joe Acaba as its chief of the Astronaut Office based in Johnson Space Center in Houston. He's served on multiple spaceflights and is a former U.S. Marine and former educator. According to NASA, he's the first person of Hispanic heritage selected to lead the office.

Acaba replaces Drew Feustel, who spent two years as deputy chief and has been acting chief of the office since NASA astronaut Reid Wiseman left the post late last year.

"Joe is an experienced space flyer and a proven leader, and he will undoubtedly inspire the next generation of NASA astronauts," says NASA Administrator Bill Nelson in a news release. " As we build on the International Space Station’s unparalleled success in low-Earth orbit with our eyes on the Moon and then Mars, Joe will play an integral role in ensuring our NASA astronauts are prepared for the challenges ahead."

Acaba, who spent a total of 306 days in space, has already supported the astronaut office in a few of roles, including director of operations in Russia and chief of the Vehicle Integration Test Office. In this new role, he will be oversee astronaut resources and operations and help develop astronaut flight crew operation concepts. Additionally, Acaba will make crew assignments for future spaceflight missions, including astronauts assigned to fly on Artemis missions.

“Our Johnson Space Center team congratulates Joe Acaba on his selection to chief of the Astronaut Office. We wish him well as he takes on this new and exciting leadership role,” says NASA Johnson Space Center Director Vanessa Wyche.

Samantha Lewis, partner at Mercury Fund

Samantha Lewis was promoted to partner at Mercury Fund. Photo courtesy of Mercury Fund

Samantha Lewis was promoted to partner from principal at Houston-based venture capital firm Mercury, per her LinkedIn. She previously was the investment director of investor network GOOSE Capital before joining the Mercury team just over two years ago.

Last year, Lewis — who also served on the board of two Houston-founded startups, Syzygy and Topl — was named a member of the Class 27 of the Kauffman Fellows Program, a group of global innovation investors.

Lewis is focused on what she calls the "power theme" at Mercury, which includes fintech, blockchain, web3, and more. She told InnovationMap on a recent episode of the Houston Innovators Podcast that these industries have been hit in particular within market uncertainty.

Bob Kleinhample, senior vice president of growth at HTX Labs

Bob Kleinhample joins HTX Labs at a time of strategic growth. Photo courtesy of HTX Labs

Virtual reality studio HTX Labs has named Bob Kleinhample as the company’s senior vice president of growth. He has more than 15 years leading business efforts in the tech space. A 20-year Army veteran, Kleinhample will oversee all aspects of HTX Labs' growth — including business development, product strategy, and marketing.

“Bob brings the right balance of market knowledge and product strategy, in combination with the commitment to bring immersive training and simulation to the warfighter, to really drive our EMPACT offering into the market,” says Scott Schneider, CEO and co-founder of HTX Labs. "We’re very excited to be adding this incredibly important role to our organization and having Bob lead these efforts as we expand the usage and adoption of EMPACT across the Department of Defense."

The appointment comes after the startup raised $3.2 million in its first outside capital round.

“Last year we secured funding from Cypress Growth Capital for the sole purpose of accelerating the growth of our EMPACT platform and our customer base, and we immediately began a search for the right person to lead these growth efforts," Schneider continues. "After performing an extensive search, we are fortunate to have connected with Bob Kleinhample who is coming on board to lead our company’s growth efforts“.

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Rice University researchers unveil new model that could sharpen MRI scans

MRI innovation

Researchers at Rice University, in collaboration with Oak Ridge National Laboratory, have developed a new model that could lead to sharper imaging and safer diagnostics using magnetic resonance imaging, or MRI.

In a study recently published in The Journal of Chemical Physics, the team of researchers showed how they used the Fokker-Planck equation to better understand how water molecules respond to contrast agents in a process known as “relaxation.” Previous models only approximated how water molecules relaxed around contrasting agents. However, through this new model, known as the NMR eigenmodes framework, the research team has uncovered the “full physical equations” to explain the process.

“The concept is similar to how a musical chord consists of many notes,” Thiago Pinheiro, the study’s first author, a Rice doctoral graduate in chemical and biomolecular engineering and postdoctoral researcher in the chemical sciences division at Oak Ridge National Laboratory, said in a news release. “Previous models only captured one or two notes, while ours picks up the full harmony.”

According to Rice, the findings could lead to the development and application of new contrast agents for clearer MRIs in medicine and materials science. Beyond MRIs, the NMR relaxation method could also be applied to other areas like battery design and subsurface fluid flow.

“In the present paper, we developed a comprehensive theory to interpret those previous molecular dynamics simulations and experimental findings,” Dilipkumar Asthagiri, a senior computational biomedical scientist in the National Center for Computational Sciences at Oak Ridge National Laboratory, said in the release. ”The theory, however, is general and can be used to understand NMR relaxation in liquids broadly.”

The team has also made its code available as open source to encourage its adoption and further development by the broader scientific community.

“By better modeling the physics of nuclear magnetic resonance relaxation in liquids, we gain a tool that doesn’t just predict but also explains the phenomenon,” Walter Chapman, a professor of chemical and biomolecular engineering at Rice, added in the release. “That is crucial when lives and technologies depend on accurate scientific understanding.”

The study was backed by The Ken Kennedy Institute, Rice Creative Ventures Fund, Robert A. Welch Foundation and Oak Ridge Leadership Computing Facility at Oak Ridge National Laboratory.

Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

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