Central Houston Inc. and its Downtown Launchpad recently took home a couple big wins. Photo courtesy of CHI

A Houston organization has been recognized for a newly opened innovation hub in downtown.

The International Economic Development Council has awarded Central Houston Inc.'s Downtown Launchpad two honors in its Excellence in Economic Development Awards Program. The new 17,000-square-foot innovation hub in Southern Downtown won a silver rank in the awards' Innovation Programs and Initiatives category and a bronze rank in the Entrepreneurship category.

"The creation of a vibrant innovation district in Downtown has been a strategic priority for Central Houston since it was identified in the 2017 Plan Downtown, our 20-year vision plan for the area's growth and development," says Bob Eury, CHI president, in a news release.

"Downtown Launchpad, which opened just last month, achieves our goal of strengthening connections between entrepreneurs, industry, startups and funders, and we're honored to see the hard work of Central Houston, Inc. and our partners recognized by the International Economic Development Council."

IEDC received over 500 submissions for 35 categories for this year's award. Each submission was evaluated by a diverse panel of economic and community developers from around the world and were looking at the nominees' efforts in creating positive change in urban, suburban and rural communities.

"The winners of IEDC's Excellence in Economic Development awards represent the very best of economic development and exemplify the ingenuity, integrity and leadership that our profession strives for each and every day," says the 2020 IEDC Board Chair and One Columbus CEO Kenny McDonald in the release. "We're honored to recognize the more than 100 communities whose marketing campaigns, projects and partnerships have measurably improved regional quality of life."

Last month, the Downtown Launchpad celebrated its grand opening. The hub is located on the 10th floor of Amegy on Main (1801 Main Street), is home to Houston's MassChallenge Texas and gener8tor accelerators and global nonprofit incubator Impact Hub Houston. The Cannon Houston is the operation partner for the space.

The Downtown Launchpad is officially open for business. Photo courtesy of the Downtown Launchpad

Innovation space in downtown Houston celebrates its grand opening

now open

Almost exactly a year ago, Central Houston Inc. and the Downtown Redevelopment Authority announced the Downtown Launchpad to emerge as a "vertical village" of innovation space. Now, as of this week, the new space has been revealed at its official grand opening.

The 17,000-square-foot innovation hub, which is located on the 10th floor of Amegy on Main (1801 Main Street), is home to Houston's MassChallenge Texas and gener8tor accelerators and global nonprofit incubator Impact Hub Houston. The Cannon Houston is the operation partner for the space.

"Downtown Launchpad innovation hub starts at the edges of technology and entrepreneurship where cutting-edge ideas can quickly be cultivated and explored," says Bob Eury, president of Central Houston and Downtown Redevelopment Authority, in a news release. "We set out to recruit and develop partnerships with some of the nation's premier accelerators and incubators in order to build an inclusive vertical village with all the critical support functions just steps away. We are excited and look forward to the impact created by the hundreds of startups that will walk through our doors."

The "vertical village" features coworking and accelerator space. Photo courtesy of the Downtown Launchpad

The new space, which has been partially open since last December, celebrated the opening with a virtual event and panel on September 30. Mayor Sylvester Turner joined the programming to recognize the Launchpad.

"To meet the challenges of today, we must empower a can-do spirit by offering a framework of resources that includes supporting startups and entrepreneurs as they seamlessly navigate through the stages of startup production — from idea generation and incorporation to talent development, investment, and scaling, as well as ensuring upskilling and reskilling to provide economic vitality for all Houstonians," Mayor Turner says at the event. "Downtown Launchpad enables this to happen. Hundreds of new businesses will be built here in the coming years."

The space, which will be used for programming and events, features a communal ground-floor lobby area with meeting rooms, a game room, workstations, and a coffee bar and deli, according to the release. There's also a dedicated event space on the building's 11th floor.

Common space are designed to enhance collisions between entrepreneurs. Photo courtesy of the Downtown Launchpad

"In the 2017 Plan Downtown, a key business strategy focuses on facilitating the creation of a collaborative Innovation District within Downtown," says Curtis Flowers, Downtown Redevelopment Authority board chair, in the release. "The purpose is to incubate a vibrant, innovative economy where startups thrive, create jobs, and attract venture capital investments to Houston which will benefit the City's long-term economic vitality. We believe the investment in establishing Downtown Launchpad will garner long-term results for Downtown and the Houston region."

The Downtown Launch Pad will house accelerator programs MassChallenge and gener8tor and coworking space from The Cannon. Photo courtesy of Downtown Launch Pa

New innovation ‘vertical village’ announced for downtown Houston

Coming soon

The Cannon Houston, a startup incubator and coworking space, and Houston-based Amegy Bank announced a partnership to create a 17,000-square-foot innovation space in downtown.

The Downtown Launch Pad is expected to open on a few floors of the Amegy Bank building at 1801 Main St. in the spring. Along with coworking space, the new hub will house MassChallenge Texas, which had its inaugural cohort earlier this year, and gener8tor, an early acceleration program announced in last month.

Mayor Sylvester Turner announced the project at Central Houston Inc.'s annual meeting on October 24. Both the accelerators that will be in the new hub received a combined combined $4 million in economic development grants from the Downtown Redevelopment Authority to be distributed over the next five years.

"Central Houston and the Downtown Redevelopment Authority are committed to establishing Downtown Houston as a nexus for innovation and a leader in urban entrepreneurship," says Bob Eury, president of both entities, in a news release. "We've found strong, strategic partners in Amegy Bank and The Cannon, both of which are committed to fostering and sustaining a vibrant innovation culture in Houston, from startup to production."

Amegy Bank has tapped Gensler for the redesign. The 13th floor of the building will house the coworking space powered by The Cannon. This space is expected to open before the end of the year.

"We originally created The Cannon to be the missing piece in Houston's startup ecosystem," says Lawson Gow, founder and CEO of The Cannon and Cannon Ventures. Gow is the son of David Gow, owner of InnovationMap's parent company, Gow Media. "Through the Cannon Tower and The Downtown Launch Pad, we are excited to join up with Central Houston, the Downtown Redevelopment Authority and Amegy Bank to create an entire 'vertical village' of innovation—a system of floors at Amegy on Main that will provide Houston's entrepreneurs with all the programs and resources they need to thrive."

The building's 10th and 11th floors will also be a part of the Downtown Launch Pad. The 10th floor will house the two accelerators, and the 11th floor will be a dedicated event space. The lobby of the building will be a common space for all members of the Cannon Tower and will have meeting rooms, a game room, work stations, a coffee bar, and a deli.

"Amegy Bank has a long history of reinvesting in the local community and supporting Texas families and businesses," says Kelly Foreman, senior vice president and corporate real estate and facilities manager for Amegy. "Now, through our partnerships with The Cannon and The Launch Pad, we are taking our commitment to small businesses to the next level by converting a part of Amegy on Main into a hub for emerging technology and start-up companies that aligns all the players across the entrepreneurial spectrum—corporations, mentors, investors, service providers and the startups themselves. This combination of offerings and capabilities will unlock significant value for Downtown, helping to attract and retain companies from not only Houston, but from around the country."

The funds will go toward bringing a new, pre-accelerator program to Houston. Shobeir Ansari/Getty Images

Downtown Redevelopment Authority approves $1.25 million grant for new-to-Houston accelerator program

New to town

Houston has yet again attracted a nationally recognized accelerator program to downtown. Wisconsin-based genera8tor has announced its plans to launch its pre-accelerator program, gBETA, in Houston in spring of next year thanks to a $1.25 million grant approved by the Downtown Redevelopment Authority.

"With gener8tor joining nonprofit global accelerator MassChallenge in Downtown, the Houston innovation ecosystem will be home to two nationally ranked accelerators," says Bob Eury, president of Central Houston and the Downtown Redevelopment Authority, in a news release. "This agreement furthers Central Houston's long-term goal to create a collaborative Innovation District within Downtown and helps bridge the gap between small local startups and the city's growing innovation economy."

The grant will not exceed $1.25 million and will be paid out over the next five years. Gener8tor will have two gBETA cohorts a year, and the seven-week program will have a max of five teams across industries. The program will be equity-free and at no cost to participants accepted into the program. The program will also host six lunch-and-learn events that will be free and open to the Houston innovation ecosystem.

"The city of Houston's leadership is supporting its community members to be the economic drivers of tomorrow," says Abby Taubner, partner at gener8tor and managing director of gBETA, in the release. "We are humbled and excited to be part of the palpable excitement surrounding the local startup ecosystem, and cannot wait to roll up our sleeves and get to work."

According to gener8tor, a third of gBETA graduates will advance to a later stage equity-based accelerator program or raise a seed round of at least $50,000, and gBETA graduates from across the organization's eight states have collectively raised $57.7 million and created 716 jobs.

This announcement comes on the heels of MassChallenge Texas launching its Houston program earlier this year, as well as Silicon Valley's Plug and Play Technology Center entering the Houston market as well this year. Houston's downtown landscape has become a major hotbed for tech and innovation, with UiPath opening a major Houston office and coworking space popping up across downtown.

"Innovation is the next economic frontier for Houston, and gener8tor's gBETA program will help bridge the gap between the city's legacy industries—energy, medicine, space exploration and the port—and our growing innovation ecosystem of startup accelerators, investors and entrepreneurs," says Mayor Sylvester Turner in the release. "gBETA is the latest leap into that future, following in the exciting footsteps of The Ion innovation hub; the relocation or expansion of Silicon Valley firms to Houston such as Bill.com, UiPath and Google Cloud; the plans for the Texas Medical Center's TMC3 translational research commercialization campus; and so much more."

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Rice research breakthrough paves the way for advanced disease therapies

study up

Bioengineers at Rice University have developed a “new construction kit” for building custom sense-and-respond circuits in human cells, representing a major breakthrough in the field of synthetic biology, which could "revolutionize" autoimmune disease and cancer therapeutics.

In a study published in the journal Science, the team focused on phosphorylation, a cellular process in the body in which a phosphate group is added to a protein, signaling a response. In multicellular organisms, phosphorylation-based signaling can involve a multistage, or a cascading-like effect. Rice’s team set out to show that each cycle in a cascade can be treated as an elementary unit, meaning that they can be reassembled in new configurations to form entirely novel pathways linking cellular inputs and outputs.

Previous research on using phosphorylation-based signaling for therapeutic purposes has focused on re-engineering pathways.

“This opens up the signaling circuit design space dramatically,” Caleb Bashor, assistant professor of bioengineering and biosciences and corresponding author on the study, said in a news release. “It turns out, phosphorylation cycles are not just interconnected but interconnectable … Our design strategy enabled us to engineer synthetic phosphorylation circuits that are not only highly tunable but that can also function in parallel with cells’ own processes without impacting their viability or growth rate.”

Bashor is the deputy director for the Rice Synthetic Biology Institute, which launched last year.

The Rice lab's sense-and-respond cellular circuit design is also innovative because phosphorylation occurs rapidly. Thus, the new circuits could potentially be programmed to respond to physiological events in minutes, compared to other methods, which take hours to activate.

Rice’s team successfully tested the circuits for sensitivity and their ability to respond to external signals, such as inflammatory issues. The researchers then used the framework to engineer a cellular circuit that can detect certain factors, control autoimmune flare-ups and reduce immunotherapy-associated toxicity.

“This work brings us a whole lot closer to being able to build ‘smart cells’ that can detect signs of disease and immediately release customizable treatments in response,” Xiaoyu Yang, a graduate student in the Systems, Synthetic and Physical Biology Ph.D. program at Rice who is the lead author on the study, said in a news release.

Ajo-Franklin, a professor of biosciences, bioengineering, chemical and biomolecular engineering and a Cancer Prevention and Research Institute of Texas Scholar, added “the Bashor lab’s work vaults us forward to a new frontier — controlling mammalian cells’ immediate response to change.”

Greentown Labs names new CEO to lead pioneering climate tech incubator

Transition News

Houston and Boston climate tech incubator Greentown Labs has named Georgina Campbell Flatter as the organization’s incoming CEO.

Flatter will transition to Greentown from her role as co-founder and executive director of TomorrowNow.org, a global nonprofit that studies and connects next-generation weather and climate technologies with communities most affected by climate change.

“We are at a transformational moment in the energy transition, with an unprecedented opportunity to drive solutions in energy production, sustainability, and climate resilience,” Flatter said in a news release. “Greentown Labs is, and has always been, a home for entrepreneurs and a powerhouse of collaboration and innovation.”

Previously, Flatter worked to launch TomorrowNow out of tomorrow.io, a Boston-based AI-powered weather intelligence and satellite technology company. The organization secured millions in climate philanthropy from partners, including the Gates Foundation, which helped deliver cutting-edge climate solutions to millions of African farmers weekly.

Flatter also spent 10 years at the Massachusetts Institute of Technology (MIT), where she was a senior lecturer and led global initiatives at the intersection of technology and social impact. Her research work includes time at Langer Lab and Sun Catalytix, an MIT – ARPA-E-funded spin-out that focused on energy storage solutions inspired by natural photosynthesis. Flatter is also an Acumen Rockefeller Global Food Systems Fellow and was closely involved with Greentown Labs when it was founded in Boston in 2011, according to the release.

“It’s rare to find an individual who has impressive climate and energy expertise along with nonprofit and entrepreneurial leadership—we’re fortunate Georgie brings all of this and more to Greentown Labs,” Bobby Tudor, Greentown Labs Board Chair and Chairman of the Houston Energy Transition Initiative, said in a news release.

Flatter will collaborate with Kevin Dutt, Greentown’s Interim CEO, and also continue to serve on Greentown’s Board of Directors, which was recently announced in December and contributed to a successful $4 million funding round. She’s also slated to speak at CERAWeek next month.

“In this next chapter, I’m excited to build on our entrepreneurial roots and the strength of our ever-growing communities in Boston and Houston,” Flatter added in a news release. “Together, we will unite entrepreneurs, partners, and resources to tackle frontier challenges and scale breakthrough technologies.”

Greentown also named Naheed Malik its new chief financial officer last month. The announcements come after Greentown’s former CEO and president, Kevin Knobloch, announced that he would step down in July 2024 after less than a year in the role.

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This article originally appeared on our sister site, EnergyCapital.

Houston firm invests $150M in leading 'lab on a chip' medical diagnostics co.

fresh funds

Houston-based health technology investment firm Hamershlag Private Capital Management Limited (HPCM) announced a $150.15 million venture investment in Patho Care LLC.

Patho Care is a “lab on a chip” medical diagnostics company known for its noninvasive point-of-care testing platforms, such as its Raman spectroscopy-based platform.

Its digital point-of-care testing devices are programmable, mobile, and reusable and can detect current or future respiratory bacterial or viral infections. The company says the technology is more cost-effective and provides results faster than traditional diagnostic methods.

“Patho Care LLC is a distinguished leader in healthcare diagnostics through the utilization of a novel approach with spectroscopy and this investment aligns with HPCM’s strategy of partnering with high-potential companies in dynamic industries,” L. Mychal Jefferson, Chairman of Hamershlag, said in a news release.

The transaction was structured as an acquisition and recapitalization using newly issued common stock and cash, which will work through a newly formed entity, PathoCare Holdings Inc. The deal will also facilitate the repayment of Patho Care LLC's existing financial obligations and settle Patho Care’s outstanding notes, helping ensure the company’s financial readiness, according to the release.

The investment will help Patho Care LLC improve operational efficiencies, broaden its service offerings and continue to innovate in the diagnostic testing space. The companies hope the collaboration will help “unlock new growth opportunities while maintaining the company’s legacy of excellence in an emerging technology,” according to a news release.

“Our commitment to delivering transformative value through innovative investments underscores our confidence in Patho Care’s vision and capabilities,” Jefferson added.