This week's roundup of Houston innovators includes Rachel Moctron of ClassPass, Sid Upadhyay of WizeHire, and Ashley Small of Medley Inc. Courtesy photos

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to three innovators across industries recently making headlines — from fitness tech and software to PR and communications.

Rachel Moncton, vice president of Global Marketing at ClassPass

Rachel Moncton shares why ClassPass tapped Houston as a prime place to expand. Photo courtesy of ClassPass

ClassPass recently announced its entrance into the Houston market, and at the helm of the company's new local presence is Rachel Moncton. In a guest article for InnovationMap, she shares why ClassPass was so interested in Houston. The search actually started four years ago, but the tech company finally landed in Houston for its fourth location.

"In 2017, the ClassPass team spent nine months conducting an intensive nationwide search for a city that matched our mission and values," Moncton writes. "As a brand focused on supporting an active lifestyle, we wanted a city that offered a connection to the outdoors. One of the most important driving factors in our search was finding a city where we could attract incredible talent to our team. Though we settled on Missoula, Houston was high on the list." Click here to read more.

Sid Upadhyay, co-founder and CEO of WizeHire

A Houston startup has closed a $7.5 million round of funding with mostly local investment. Photo courtesy of WizeHire

Sid Upadhyay's startup has something to celebrate. The software company founded in Houston closed a $7.5 million series A round of funding led by two Houston-area venture capital firms — Amplo and Mercury Fund. According to a news release, WizeHire will use the funds to scale their business, which is centered around providing personalized hiring resources to small businesses.

"We're a small business helping small businesses with a team of people looking out for you," says Upadhyay. "Hiring is complex and personal. Our customers see what we do not just as software; they see us as a trusted advisor." Click here to read more.

Ashley Small, founder and CEO of Medley Inc.

From events to online shopping — here are four tech trends to look out for this year according to Ashley Small. Photo courtesy of Medley

For Ashley Small, founder and CEO of Medley Inc., innovation and inclusion go hand in hand. Business leaders need diverse voices at the table to drive new ideas and innovation.

"Innovation is actually impossible without diversity," Small says on the most recent episode of the Houston Innovators Podcast. "A part of this is also being really open minded to the fact that you are going to hear ideas that sound and look different. Be open to that, because that is 100 percent the point."

Small discusses more about how she's honoring Black History Month with her team and the evolution the PR and media industries have seen over the past decade on the episode. Click here to stream the episode and read more.

Ashley Small, founder and CEO of Medley Inc., joins the Houston Innovators Podcast this week to discuss COVID-19's affect on her business and fostering diversity at startups. Photo courtesy of Medley Inc.

Houston founder calls for business leaders to 'make room for diverse voices'

HOUSTON INNOVATORS PODCAST EPISODE 70

Last year was one of quick pivots and tech solutions for Ashley Small and her company's clients. Small — the CEO and founder of Medley Inc., a Houston-based branding and public relations firm — works with both for-profit and nonprofit entities to tell their stories, and of course 2020 had its challenges in doing so. But they weren't anything Small, her team, and technology couldn't overcome.

Small founded Medley over 12 years ago, and for the past three of those years, her team has been completely virtual. She shares on the Houston Innovators podcast that this give her team a headstart on being able to find and quickly adopt quick tech solutions — but last year's shutdown also meant navigating this for all her clients.

"The biggest obstacle we had to overcome was figuring out what the best technology was for each client," Small says. "Where the learning curve has been is understanding all the available resources out there and understanding how offline experiences can help audiences connect online."

Founded in Houston, Medley has grown to the Los Angeles and Chicago markets over the years — and Small says that was intentional. An Oklahoma native, Small fell in love with Houston's diversity when she attended Texas Southern University, and sought out other diverse markets to expand her business. And, as a Black female founder, she fosters an inclusive community at her company — and wants to remind her fellow business owners how imperative it is to running an innovative company.

"Innovation is actually impossible without diversity," Small says, adding that when you bring different people to the table, you get new ways of thinking. "A part of this is also being really open minded to the fact that you are going to hear ideas that sound and look different. Be open to that, because that is 100 percent the point."

Small knows early-stage companies aren't always able to hire a bunch of people from diverse backgrounds right from the start, but there are other ways to surround yourself with diverse ideas.

"Make room for diverse voices -- and you may have to be a bit creative," Small says.

Medley's team also realizes that not every startup can afford to bring on an in-house or third-party PR team, but the company has a few options for startups, such as a three-month retainer to start as well as a series of workshops available online for as low as $19.

Small discusses more about how she's honoring Black History Month with her team and the evolution the PR and media industries have seen over the past decade on the episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


This week's roundup of Houston innovators includes Nicole Rogers of Validere, Allie Danziger of Ampersand, and Ashley Small of Medley Inc. Courtesy photos

3 female Houston innovators to know this week

who's who

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to three female innovators across industries — from energy tech to business entrepreneurship.

Nicole Rogers, senior vice president at Validere

Nicole Rogers, senior vice president at Validere, joins the Houston Innovators Podcast to discuss how her company has grown exponentially over the past year. Photo courtesy of Validere

Nicole Rogers joined Canadian startup Validere during the summer last year — right smack dab in the middle of a pandemic. But despite COVID-19 and the drop in oil prices, the energy company grew exponentially — in clientbase, in venture capital support, and in employee count.

"One of the things we found that was to our advantage throughout the pandemic was a lot of folks in oil were having a career identity crisis. Oil really struggles with employment elasticity," Rogers says. "A lot of the colleagues we were talking to were just fatigued with the ups and downs going on in the past decade."

Rogers, who's based in the company's Houston office, shares more about Validere's growth and opportunities in the new year — plus what she thinks Houston needs to do to maintain its status of energy capital of the world in the episode. Click here to read more and to stream the podcast.

Allie Danziger, founder of Ampersand

Houston entrepreneur, Allie Danziger, wanted to create a program for young professionals looking to gain experience in unprecedented times. Photo courtesy of Ampersand

Allie Danziger has two small children, but she started thinking about if her kids were college age, would she want them to enroll in a virtual college experience or hold off for a time where they could have a more traditional experience. Realizing she probably wasn't alone, she thought about how she could create an alternative for high school grads — in this time of the pandemic but also in a time where college degrees aren't the best option for job security.

"I really believe that it scales way beyond this pandemic," says Danziger. In her research, she saw a lack of career-focused gap curriculums and resources available. "There are no programs that help you determine what the right path for you is—to really do that self-exploration and then apply it to your career path," she explains. Click here to read more.

Ashley Small, founder and CEO of Medley Inc.

From events to online shopping — here are four tech trends to look out for this year according to Ashley Small. Photo courtesy of Medley

It's a new year and the perfect time to reflect on where society is at from a technological standpoint. In light of the pandemic and an overarching trend of tapping into tech to provide solutions to COVID-19-related challenges, 2021 will likely see more of these trends.

"As a business owner, it's clear to me that many of these shifts will persist long after the pandemic has ended," writes Ashley Small, founder and CEO of Medley Inc., in a guest column for InnovationMap.

From subscriptions to online shopping, Small highlighted the types of tech in the digital realm that deserve our special attention in 2021. Click here to read more.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.