research roundup

These are the latest COVID-19-focused research projects happening at Houston institutions

A new AI-optimized COVID screening device, a free response resource, and more — here's your latest roundup of research news. Image via Getty Images

Researchers across the Houston area are working on COVID-19 innovations every day, and scientists are constantly finding new ways this disease is affecting humankind.

From a COVID breathalyzer to a new collaboration in Houston — here's your latest roundup of local coronavirus research news.

A&M System to collaborate on a COVID-19 breathalyzer

A prototype of the device will be used on the Texas A&M campus. Photo via tamu.edu

Researchers at Texas A&M University System are collaborating on a new device that uses artificial intelligence in a breathalyzer situation to detect whether individuals should be tested for COVID-19. The technology is being developed through a collaboration with Dallas-based company, Worlds Inc., and the U.S. Air Force.

The device is called Worlds Protect and a patient can use a disposable straw to blow into a copper inlet. In less than a minute, test results can be sent to the person's smartphone. Worlds Inc. co-founders Dave Copps and Chris Rohde envision Worlds Protect kiosks outside of highly populated areas to act as a screening process, according to a news release.

"People can walk up and, literally, just breathe into the device," says Rohde, president of Worlds Inc., in the release. "It's completely noninvasive. There's no amount of touching. And you quickly get a result. You get a yay or nay."

The university system has contributed $1 million in the project's development and is assisting Worlds Inc. with engineering and design, prototype building and the mapping of a commercial manufacturing process. According to the release, the plan was to test the prototypes will be tried out this fall on the Texas A&M campus.

"Getting tech innovations to market is one of our sweet spots," says John Sharp, chancellor of the Texas A&M System, in the release. "This breakthrough could have lasting impact on global public health."

Baylor College of Medicine researchers to determine cyclosporine’s role in treating hospitalized COVID-19 patients

BCM researchers are looking into the treatment effect of an existing drug on COVID-19 patients. Photo via BCM.edu

The Baylor College of Medicine has launched a randomized clinical trial to look into how the drug cyclosporine effects the prevention of disease progression in pre-ICU hospitalized COVID-19 patients. The drug has been used for about 40 years to prevent rejection of organ transplants and to treat patients with rheumatoid arthritis and psoriasis.

"The rationale is strong because the drug has a good safety profile, is expected to target the body's hyperimmune response to COVID and has been shown to directly inhibit human coronaviruses in the lab," says Dr. Bryan Burt, chief of thoracic surgery in the Michael E. DeBakey Department of Surgery at Baylor, says in a press release.

Burt initiated this trial and BCM is the primary site for the study, with some collaboration with Brigham and Women's. The hypothesis is that the drug will help prevent the cytokine storm that patients with COVID-19 experience that causes their health to decline rapidly, according to the release.

The study, which is funded by Novartis, plans to enroll 75 hospitalized COVID-19 patients at Baylor St. Luke's Medical Center who are not in the ICU. There will be an initial evaluation at six months but Burt expects to have the final study results in one year.

Rice launches expert group to help guide pandemic response

A new response team is emerging out of a collaboration led by Rice University. Photo courtesy of Rice

Rice University is collaborating with other Houston institutions to create the Biomedical Expert Panel, supported by Texas Policy Lab, to assist officials in long-term pandemic recovery.

"Not all agencies and decision-makers have an in-house epidemiologist or easy access to leaders in infectious disease, immunology and health communications," says Stephen Spann, chair of the panel and founding dean of the University of Houston College of Medicine, in a news release. "This panel is about equity. We must break out of our knowledge siloes and face this challenge together, with a commitment to inclusivity and openness."

The purpose of the panel is to be available as a free resource to health departments, social service agencies, school districts and other policymakers. The experts will help design efficient public health surveillance plans, advise on increasing testing capacity and access for underserved communities, and more.

"The precise trajectory of the local epidemic is difficult to predict, but we know that COVID-19 will continue to be a long-term challenge," says E. Susan Amirian, an epidemiologist who leads the TPL's health program, in the release. "Although CDC guidelines offer a good foundation, there is no one-size-fits-all approach when managing a crisis of this magnitude across diverse communities with urgent needs."

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A new sports festival is headed to Houston next year. Rendering courtesy of Pokatok

A Houston team announced their plans to bring the “world’s fair for sports” to downtown Houston in April 2024.

Pokatok, the four-day festival, will feature a sports tech expo, a film festival, speakers and panels, live music, pitch competitions, and more. The venue will be George R. Brown Convention Center, Discovery Green, and various nearby hotels, according to the release.

Gow Companies, founded by Lawson Gow (who is the son of David Gow, InnovationMap's parent company's CEO), announced that the team has secured support from Houston First, the Greater Houston Partnership, and the Harris County Houston Sports Authority to put on the event, which is slated to take place April 4-7, 2024. The company also owns Houston Exponential and a sports accelerator called Pokatok Labs.

“Pokatok will not only be the largest gathering of the entire sports tech ecosystem, it will also be a true fan festival for sports enthusiasts,” says Gow in the news release. “Everyone speaks the language of sport, it’s an incredibly powerful unifier of our society, and this festival will bring together people from around the world to experience hundreds of events revolving around the new and the next in sport.”

The festival will take place in April 2024 in downtown. Rendering courtesy of Pokatok

The festival will feature two tracks — one focused on sports innovation and the other surrounding a fan experience. Pokatok X will include an expo and showcase focused on sports innovation, bringing together startups, investors, accelerators, athletes, and industry experts to dive into sports tech.

The Pokatok Fan Festival's track will include product releases, demos for sports technology, sporting events, competitions, tournaments, and more.

Houston is no stranger to hosting major sport events, Harris County - Houston Sports Authority CEO Janis Burke points out in the news release, including the 2023 NCAA Men’s Final Four and the upcoming 2024 College Football National Championship, the 2024 Cricket World Cup, and the 2026 FIFA World Cup.

"Houston is known as one of the best sports destinations in the world," Burke continues. "As an organization, we are consistently looking for ways to innovate and grow in the sports sector. Events like Pokatok are great for advancing sports within the region and providing unique opportunities for our community!"

Tickets are expected to go on sale in the fall, and the organization is looking for potential speakers and partners. The festival's name derives from sport of pok-a-tok, which dates back thousands of years as the world’s first team sport played throughout Mesoamerica.

“The City of Houston is a sports town to its core and has been host to some of the greatest events and moments in sports,” says Mayor Sylvester Turner in the release. “Pokatok will help further Houston’s vision of being a destination city for global sporting events and innovations. The business community also supports this venture, and I thank them for their involvement and support. This project is an excellent example of local business leaders joining forces to expand the attractions the City has to offer to both residents and visitors.”

Pokatok will take place in and around the George R. Brown Convention Center. Rendering courtesy of Pokatok

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