Annual Houston student startup competition doles out over $1.5M in cash, investment prizes

winner, winner

Thirteen of the 42 teams participating in RBPC 2024 walked away with investment funding. Photo courteys of Rice University

For the 24th year, the Rice Alliance for Technology and Entrepreneurship hosted its Rice Business Plan Competition, facilitating over $1.5 million in investment and cash prizes to the top teams.

The 42 startups competing this year, which were announced earlier this year and included teams from around the world, participated in the three-day event that culminated in a reception on Saturday, April 6. The companies were divided into five categories: Energy, Cleantech and Sustainability; Hard Tech; Life Sciences and Healthcare Solutions; Digital Enterprise; Consumer Products and Services.

“We award the competitors $1 million in prizes, prizes that serve as foundational capital to launch their startup,” RBPC Director Catherine Santamaria says at the awards gala. “That’s a large number of prizes, but the biggest thing our startups leave with is a feeling of generosity and community from this room. This community is always ready and willing to help our founders and support our vision for the competition by investing time, money and resources in these student innovators.”

While all participating teams received $950 for being selected, several teams walked away with thousands in funding, cash, and in-kind prizes. Here's which companies won big.

MesaQuantum, Harvard University — $335,000

MesaQuantum is developing accurate and precise chip-scale clocks. While not named a finalist, the company secured the most amount of funding across a few prizes:

$250,000 OWL Investment Prizes
$60,000 nCourage Courageous Women Entrepreneur Investment Prize
$25,000 Jacobs, Intuitive Machines and WRX Companies Rising Stars Space Technology and Commercial Aerospace Cash Prize

Protein Pints, Michigan State University — $251,000

The big winner of the night was Protein Pints, a high-protein, low-sugar, ice cream product from Michigan State University. Not only did the company win first place and the $150,000 GOOSE Capital Investment Grand Prize, as decided by the more than 350 judges, but it won a few other investment prizes, including:

$100,000 The Indus Entrepreneurs (TiE) Texas Angels Investment Prize — Protein Pints, Michigan State University
The Eagle Investors Prize
$1,000 Anbarci Family Company Showcase Prize
Mercury Elevator Pitch Competition Prize (Best in Consumer Products)
An invitation to Entrepreneur Magazine's elevator pitch show

Osphim, RWTH Aachen University —$201,000

Osphim, a data acquisition and monitoring platform from Germany, won these prizes despite not being named a finalist:

$200,000 Goose Capital Investment Prize
$1,000 Anbarci Family Company Showcase Prize
Mercury Elevator Pitch Competition Prize (Best in Digital)

Somnair, Johns Hopkins University — $200,000

Taking second place and a $100,000 from David Anderson, Jon Finger, Anderson Family Fund, Finger Interests, Greg Novak and Tracy Druce was Somnair is a novel non-invasive neurostimulation device for the treatment of obstructive sleep apnea. The company also won:

$100,000 Houston Angel Network Investment Prize
Mercury Elevator Pitch Competition Prize (Best in Life Science)
An invitation to Texas Medical Center's Accelerator Bootcamp
An invitation to Entrepreneur Magazine's elevator pitch show

Icorium Engineering Company, University of Kansas — $171,000

Icorium Engineering Company — a chemical engineering startup developing technologies to make sustainable, circular economies a reality for refrigerants and other complex chemical mixtures — won fifth place and a $5,000 prize sponsored by Norton Rose Fulbright, EY, Chevron Technology Ventures and Shell Ventures, as well as:

$100,000 OWL Investment Prizes
$40,000 nCourage Courageous Women Entrepreneur Investment Prize
$25,000 from Finger Interests, the Anderson Family Fund at the Greater Houston Community Foundation, Greg Novak and Tracy Druce
$1,000 Anbarci Family Company Showcase Prize
Mercury Elevator Pitch Competition Prize (Best in Energy, Sustainability)
An invitation to Entrepreneur Magazine's elevator pitch show

Informuta, Tulane University — $70,000

Informuta's proprietary technology leverages DNA sequencing to predict if bacteria will respond to different antibiotics or, for the very first time, develop future resistance thus causing treatment failure. The company won fourth place and a $5,000 prize sponsored by Norton Rose Fulbright, EY, Chevron Technology Ventures and Shell Ventures.

$40,000 Pearland EDC Spirit of Entrepreneurship Cash Prize
$25,000 from Finger Interests, the Anderson Family Fund at the Greater Houston Community Foundation, Greg Novak and Tracy Druce

EndoShunt Medical, Harvard University — $55,000

EndoShunt created a rapid, targeted blood flow control device to be use in emergency or trauma settings. The company won sixth place and the $5,000 prize, sponsored by Norton Rose Fulbright, EY, Chevron Technology Ventures and Shell Ventures, as well as:

$25,000 Southwest National Pediatric Device Consortium Pediatric Device Cash Prize
$25,000 from Finger Interests, the Anderson Family Fund at the Greater Houston Community Foundation, Greg Novak and Tracy Druce

Power2Polymers, RWTH Aachen University —$50,000

Tackling the challenge of forever chemicals, Power2Polymers is creating safe alternatives free of forever chemicals. The German company took third place and the $50,000 investment sponsored by Finger Interests, the Anderson Family Fund at the Greater Houston Community Foundation, Greg Novak and Tracy Druce. The company also won the Mercury Elevator Pitch Competition Prize (Best Overall).

D.Sole, Carnegie Mellon University — $30,000

D. Sole won the wild card ticket to the finals and took seventh place. The company is advancing the development of remote patient monitoring in podiatry with foot insoles designed for the early detection and monitoring of diabetic foot complications, such as ulcers and deformities. They also won $30,000 from Finger Interests, the Anderson Family Fund at the Greater Houston Community Foundation, Greg Novak and Tracy Druce.

Other prizes:

$25,000 New Climate Ventures Sustainable Investment Prize went to Oxylus Energy from Yale University
$25,000 Dream Big Ventures Latino Entrepreneur Investment Prize went to Dendritic Health AI from Northwestern University
$25,000 NOV Energy Technology Innovation Cash Prize went to LiQuidium from the University of Houston
$25,000 Urban Capital Network Diversity Investment Prize in Partnership with South Loop Venture Investment Prize went to TouchStone from University of California, Berkeley

Brad Burke has been named associate vice president for industry and new ventures within Rice University's Office of Innovation. Photo by Jeff Fitlow/Rice University

Houston innovation leader named to new role to drive strategy, programming

supporting innovators

A longtime Houston innovation leader has added a new title to his role at Rice University.

Brad Burke, who has served as executive director of the Rice Alliance for Technology and Entrepreneurship for 20 years, has been named associate vice president for industry and new ventures, the university announced this week. He will take on this new role within the Office of Innovation, as well as continue leading the Rice Alliance.

Rice's Office of Innovation, which was established in 2022 with the appointment of Chief Innovation Officer and Vice President for Innovation Paul Cherukuri, exists to support new and innovative initiatives and technologies from the Rice community with mentorship, funding, pilots, and more.

“The Rice Alliance has played a key role over the past two decades in building Rice’s reputation as a leading institution for innovation and entrepreneurship,” Cherukuri says in a news release. “We are thrilled to have Brad Burke join the Office of Innovation to support our faculty and students in commercializing their inventions.”

Burke has played a major role in the collaboration of Houston for the past 20 years leading the Rice Alliance, which coordinates many event programs and accelerators — including the Rice Business Plan Competition, energy and life science forums, the Clean Energy Accelerator, Owl Spark, Blue Launch, and more.

Last year, Burke received the Outstanding Contributions to Advancing Innovation and Entrepreneurship in Higher Education Award at the 2023 Deshpande Symposium for Innovation and Entrepreneurship in Higher Education. He also accepted the 2023 Trailblazer Award at the Houston Innovation Awards.

Last fall, Rice University's Office of Innovation established the One Small Step Grant — named for Neil Armstrong's first words spoken from Tranquility Base just several years after JFK's speech at Rice. The program will provide funding to faculty working on "promising projects with commercial potential," according to the website.

The Office of Innovation also grew its team last August with the appointment of Houston materials scientist-turned-entrepreneur Adrian Trömel as its new assistant vice president for strategy and investments.

In 2022, Brad Burke joined the Houston Innovators Podcast to discuss the work he and his team do at Rice Alliance.

This year, seven of the 10 most-promising life science companies are based in Houston. Photo courtesy of Rice Alliance

Houston startups dominate ‘most-promising’ companies announcement at annual event

on the list

Rice University played host this week to the 12th annual Texas Life Science Forum, where life science leaders and startup founders could network, learn and present pitches on their solutions to a wide array of health-related issues.

Hosted by Rice Alliance for Technology and Entrepreneurship and BioHouston on November 7, the event brought together more than 600 attendees for a series of keynote speakers and panels. This year, 45 early-stage therapeutic, diagnostic, medical device and digital health companies—many of which are based in Houston—also pitched their concepts.

Fort Worth-based AyuVis Research walked away from the event with the two top recognitions: The Michael E. DeBakey Memorial Life Science Award and the People's Choice Award. The company, which has developed a small molecule immunotherapy targeting bronchopulmonary dysplasia (BPD) in preterm neonates and other respiratory disorders. The company is raising a $20 million Series A round to support its clinical development and is slated to pitch at IGNITE Health’s Fire Pitch 2023 today, November 9, at the Ion.

Each year the Rice Alliance and BioHouston also name its 10 most promising life science companies, selected by investors—seven out of 10 of which are based in Houston. This year's selection included the following companies, in alphabetical order:

7 Hills Pharma: This Houston-based clinical stage immunotherapy company has developed the concept of allosteric activation of integrins to facilitate cell adhesion and promote immune responses. The concept has uses in preventing infection and cancer, and increasing the effectiveness of oncology drugs and infectious disease vaccines.
Bairitone Health: This Houston-based company is building a scalable diagnostic system for sleep apnea anatomy utilizing home-use wearable, passive Sonar technology and AI techniques.
Diakonos Oncology: Also based in Houston, Diakonos' Dendritic Cell Vaccine was awarded the FDA’s Fast Track designation. The clinical-stage biotech company's immunotherapies have shown early successes for hard-to-reach, aggressive cancers like Glioblastoma Multiforme.
Mongoose Bio: With more than 20 years of research, Mongoose specializes in T cell-based therapies for diverse solid tumors TCR-based therapies in cancer patients. The Houston-based company has developed an immunopeptidome discovery platform for TCR-based therapies in cancer patients.
Nandi Life Sciences: Nandi is developing antibodies for Avastin-resistant ovarian cancer, with
further application in breast, colorectal and lung cancer. The company is based out of Texas Medical Center Innovation.
NKILT Therapeutics: This Houston-based company's seed-stage cell therapy has applications in solid tumors, such as colorectal cancer, ovarian cancer, clear cell renal carcinoma, endometrial
cancer and more. It is developing a novel and proprietary Chimeric ILT-Receptor.
NuVision Biotherapies: Based in the United Kingdom, NuVision has developed and proven a treatment for dry eye disease. It's known for its Omnigen and OmniLenz products and is raising a series A to scale, take the business to profitability and exit.
Panakeia Technologies: Also based in the UK, Panakeia has developed an AI-based software that can provide multi-omic biomarkers in minutes. Currently this process takes days or weeks. It's RuO platform can identify 4,500 known multi-omics cancer markers.
Taurus Vascular: A recent spin-out of the Texas Medical Center Innovation Biodesign program, Taurus is developing a novel, catheter-based solution for treating endoleaks, which can be related to aortic aneurysms.
YAP Therapeutics: The only California-based company to make the cut, this preclinical-stage biotech develops genetic medicines that leverage the company’s tissue renewal and regeneration platform to reverse and cure severe diseases, including heart failure, pulmonary diseases, retinal degeneration and hearing loss.

Last year, Bairitone Health took home the DeBakey and People's Choice awards.

The 2023 Houston Innovation Awards revealed its big winners across 13 categories. Photos courtesy

Houston Innovation Awards winners revealed at 2023 event

drum roll, please...

Who are the top innovators and startups in Houston? We just found out for you.

The Houston Innovation Awards honored over 50 finalists categories, naming the 12 winners at the event. The 2023 Trailblazer Award recipient, Brad Burke, managing director of the Rice Alliance for Technology and Entrepreneurship, was also honored at the event by inaugural winner, Barbara Burger.

The 2023 judges — who represent various industries and verticals in Houston — scored over 200 submissions. The event, hosted November 8 in partnership with Houston Exponential and emceed by Scott Gale, executive director of Halliburton Labs, revealed the winners.

The event's sponsors included Halliburton Labs, Microsoft, The Ion, Houston Community College, Houston Energy Transition Initiative, NOV, Tito's Handmade Vodka, Uncle Nearest Premium Whisky, 8th Wonder Brewery, and 8th Wonder Cannabis.

Without further adieu, here the winners from the 2023 Houston Innovation Awards.

BIPOC-Owned Business: Milkify

The winner of the BIPOC-Owned Business category, honoring an innovative company founded or co-founded by BIPOC representation, is Milkify, a service that turns breast milk into a shelf-stable powder.

Female-Owned Business: The Postage

The winner of the Female-Owned Business category, honoring an innovative company founded or co-founded by a woman, is The Postage, a comprehensive life planning and succession software platform for families and small businesses.

Hardtech Business: Syzygy Plasmonics

The winner of the Hardtech Business category, honoring an innovative company developing and commercializing a physical technology, is Syzygy Plasmonics, a deep decarbonization company that builds chemical reactors designed to use light instead of combustion to produce valuable chemicals like hydrogen and sustainable fuels.

Digital Solutions Business: RepeatMD

The winner of the Digital Solutions Business category, honoring an innovative company developing and programming a digital solution to a problem in an industry, is RepeatMD, software platform for customer loyalty, eCommerce, and fintech solutions to enhance the patient experience and provide a new source of revenue for the aesthetics and wellness space.

Social Impact Business: ALLY Energy

The winner of the Social Impact Business category, honoring an innovative company providing a solution that would enhance humanity or society in a significant way, is ALLY Energy, helping energy companies and climate startups find, develop, and retain great talent.

Sustainability Business: Fervo Energy

The winner of the Sustainability Business category, honoring an innovative company providing a solution within renewables, climatetech, clean energy, alternative materials, circular economy, and beyond, is Fervo Energy, leveraging proven oil and gas drilling technology to deliver 24/7 carbon-free geothermal energy.

Life Science Business: CellChorus

The winner of the Life Science Business category, honoring an innovative company within the health and medical industries designing a treatment or technology, is CellChorus, using AI to evaluate immune cell function and performance to improve the development and delivery of therapeutics.

Corporate of the Year: Houston Methodist

The winner of the Corporate of the Year category, honoring a corporation that supports startups and/or the Houston innovation community, Houston Methodist, a hospital system and health care innovation leader.

DEI Champion: Calicia Johnson

The winner of the DEI Champion, honoring an individual who is leading impactful diversity, equity, and inclusion initiatives and progress within Houston and their organization, is Calicia Johnson, chair of Blacks at Microsoft Houston.

Ecosystem Builder: Joey Sanchez

The winner of the Ecosystem Builder category, honoring an individual who has acted as a leader in developing Houston’s startup ecosystem, is Joey Sanchez, founder of Cup of Joey and senior director of ecosystems at the Ion.

Mentor of the Year: Wade Pinder

The winner of the Mentor of the Year category, honoring an individual who dedicates their time and expertise to guide and support to budding entrepreneurs, is Wade Pinder, founder of Product Houston.

People's Choice:

The winner of the People's Choice: Startup of the Year category, selected via an interactive voting portal during the event, is Blue People, helping bring ideas to life through software development expertise.

This week's roundup of Houston innovators includes Kelsey Hultberg of Sunnova, Brad Burke of Rice Alliance, and Yaxin Wang of the Texas Heart Institute. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health care to energy tech — recently making headlines in Houston innovation.

Kelsey Hultberg, executive vice president of corporate communications and sustainability of Sunnova Energy International

Kelsey Hultberg, executive vice president of corporate communications and sustainability at Sunnova Energy, joins the Houston Innovators Podcast. Photo courtesy of Sunnova

Several years ago, Kelsey Hultberg decided to make a pivot. Looking for a role with career growth opportunities, the communications professional thought she'd find something at an oil and gas company, but then she met John Berger, founder and CEO of Sunnova, who was looking for someone to stand up their communications team amidst the solar energy company's growth.

"He hooked me," Hultberg shares on the Houston Innovators Podcast. "He said, 'I've got big plans for this company. I see where this energy industry is going, I see that we're prime for a transition, and I want to take this company public.' And I started a few weeks later."

Hultberg has been telling the story for Sunnova — which equips customers with solar and storage technology, providing them with energy independence — ever since, through scaling, new technologies, and its IPO in 2019. Read more.

Houston Innovation Awards names longtime Rice leader as 2023 Trailblazer

Brad Burke has been named the 2023 Trailblazer Award recipient. Photo via alliance.rice.edu

In less than a month, all of Houston's innovation community's movers and shakers will gather to celebrate the Houston Innovation Awards, and the night's first honoree has officially been named.

Brad Burke, managing director of the Rice Alliance for Technology and Entrepreneurship, was selected to receive the 2023 Trailblazer Award. The award was established to recognize an individual who has already left a profound impact on Houston's business and innovation ecosystem and is dedicated to continuing to support Houston and its entrepreneurs.

The award, which is selected from a group of internal and external nominations, was decided by a vote of the 2023 awards judges, who represent Houston's business, investment, and entrepreneurial community across industries. Read more.

Yaxin Wang leads the IDEA Lab at the Texas Heart Institute. Photo via texasheart.org

Meet Yaxin Wang, PhD. The research engineer leads the IDEA Lab at the Texas Heart Institute. IDEA stands for Innovative Device & Engineering Applications, an apt description of what Wang and her colleagues do. She’s currently focused intensely on projects that could radically change transplantation for patients in need of an artificial heart or new, healthy lungs.

Specifically, Wang is helping to develop a pediatric left ventricular assist device (NeoVAD) to mechanically pump that part of the heart in infants and small children born with heart defects.

“There aren’t a lot of options for very small kids,” explains Wang. “That’s why we’re working on an implantable LVAD for very young kids.” Read more.

Here's what energy transition companies stood out to Rice Alliance's experts. Photo via Rice Alliance

10 startups named most-promising in energy tech at Houston conference

rising stars

At the 20th annual Energy Tech Venture Forum presented by Rice Alliance for technology and Entrepreneurship, 11 startups scored recognition from the event's investors who evaluated over 90 early-stage energy transition companies.

"The selection process was both exhilarating and challenging given the incredible ideas we've seen today," says Jason Sidhu, director of information services business engagement at TC Energy, who announced the top companies. "I want to extend my gratitude to every company that participate din this year's Energy Tech Venture Forum. Your commitment to solving energy problems and pursuing ambitions ideas is truly commendable."

In addition to the top 10 most-promising companies, the event's attendees decided the people's choice pick out of the 50 or so pitching companies. The winner of that recognition was Calgary, Alberta-based Galatea Technologies, which has created a tech platform to enhance workflows for operational, financial, and environmental performance.

The top companies, according to the Rice Alliance experts and investors, were:

Circular economy startup, Polystyvert. Based in Montreal, the company has created a unique dissolution recycling process that creates a material that can contribute to cutting carbon emissions by up to 90 percent.
United Kingdom-based Mirico provides a tracking technology to its customers to measure climate gases (like methane, carbon dioxide, nitrous oxide, and ammonia), across areas up to half a square mile and in all conditions.
Protein Evolution, from New Haven, Connecticut, taps into a combination of green chemistry and enzyme technology to break down synthetic polymers.
Another Canadian company, Ayrton Energy, based in Calgary, created a liquid organic H2 carrier (LOHC) storage technology presents an opportunity for large, scalable and efficient transport of H2 over long distances.
Also representing New Haven, Connecticut, Carbon Loop is on a mission to make carbon capture and conversion scalable through carbon dioxide electrolysis using a proprietary catalyst to convert captured carbon dioxide into methanol.d
Based in London, Mobilus Labs has designed a new way for frontline communication with an in-helmet hardware and software solution. software solution designed for the frontline workforce.
1s1 Energy, based in California, is working on producing low-cost green hydrogen by creating new materials to unlock unprecedented electrolyzer efficiency, durability, and more.
From Skokie, Illinois, Numat is specializing in solutions within Metal-organic framework (MOF) research to enhance the process of separating the hazardous chemicals negatively impacting human health and the environment.
Mantel, headquartered in Cambridge, Massachusetts, created a molten borate technology to capture CO2 in a new and efficient way.
The lone Houston-based company, Mars Materials is working to produce acrylonitrile using CO2 and biomass to enable decarbonization applications in carbon fiber and wastewater treatment.

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This article originally ran on EnergyCapital.

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2 Houston startups selected by US military for geothermal projects

hot new recruits

Two clean energy companies in Houston have been recruited for geothermal projects at U.S. military installations.

Fervo Energy is exploring the potential for a geothermal energy system at Naval Air Station Fallon in Nevada.

Meanwhile, Sage Geosystems is working on an exploratory geothermal project for the Army’s Fort Bliss post in Texas. The Bliss project is the third U.S. Department of Defense geothermal initiative in the Lone Star State.

“Energy resilience for the U.S. military is essential in an increasingly digital and electric world, and we are pleased to help the U.S. Army and [the Defense Innovation Unit] to support energy resilience at Fort Bliss,” Cindy Taff, CEO of Sage, says in a news release.

A spokeswoman for Fervo declined to comment.

Andy Sabin, director of the Navy’s Geothermal Program Office, says in a military news release that previous geothermal exploration efforts indicate the Fallon facility “is ideally suited for enhanced geothermal systems to be deployed onsite.”

As for the Fort Bliss project, Michael Jones, a project director in the Army Office of Energy Initiatives, says it’ll combine geothermal technology with innovations from the oil and gas sector.

“This initiative adds to the momentum of Texas as a leader in the ‘geothermal anywhere’ revolution, leveraging the robust oil and gas industry profile in the state,” says Ken Wisian, associate director of the Environmental Division at the U.S. Bureau of Economic Geology.

The Department of Defense kicked off its geothermal initiative in September 2023. Specifically, the Army, Navy, and Defense Innovation Unit launched four exploratory geothermal projects at three U.S. military installations.

One of the three installations is the Air Force’s Joint Base San Antonio. Canada-based geothermal company Eavor is leading the San Antonio project.

Another geothermal company, Atlanta-based Teverra, was tapped for an exploratory geothermal project at the Army’s Fort Wainwright in Alaska. Teverra maintains an office in Houston.

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This article originally ran on EnergyCapital.

Houston investor calls for all angels to move the ecosystem forward

houston innovators podcast episode 233

One of the biggest components of a well-functioning startup ecosystem is inarguably access to capital, and Mitra Miller is dedicated to enhancing education around investment and growing Houston's investor base.

As vice president and board member of the Houston Angel Network, the oldest angel network in Texas and one of the most active angel networks in the country, Miller strives to provide guidance to new and emerging angel investors as well as founders seeking to raise money from them.

"Most founders have no idea or understanding of how investors think — we are not an ATM," Miller says on the Houston Innovators Podcast. "We are really partners you are getting married to for the next 5, 8, 10 years — sometimes longer. We need to bring your allies in every sense of the word."

HAN, a nonprofit, provides a unique opportunity for its members, as Miller explains. The group consists of around 100 individuals from all business backgrounds, so evaluating companies together brings more than just a wealth of capital — but also a wealth of knowledge.

"What HAN provides is access to investments," Miller says, adding that members have the benefit in evaluating companies together with people from different backgrounds. "Inside a group like HAN, we have extraordinary expertise."

In addition to educating both founders and investors in the process, Miller has dedicated herself to providing opportunities for students in low-income parts of Houston to learn about the startup world. Eight years ago, she founded Eagle Investors, an organization that provides a year-long program that culminates in a group of students participating as judges for the Rice Business Plan Competition.

"They spend a year learning about innovation, entrepreneurship, and investing by meeting local investors, entrepreneurs, and service providers. They go around Houston to get to visit and ... experience all of the ecosystem," Miller says.

At RBPC, the cohort of high school students evaluate the pitches and select a company to provide a $5,000 prize.

Miller herself has been a judge at RBPC for 20 years now, and she's had a front row seat for watching Houston develop as an ecosystem. She's seen the city make real progress, but has one major call to action.

"The piece that I am most aware of that I would like to see grow is activating more accredited investors who are interested in this asset class of early-stage companies and plugging in," Miller says. "They can also invest their time and knowledge to help companies in our region grow and scale."

Report: Houston secures spot on list of top 50 startup cities

by the numbers

A new ranking signals great promise for the growth of Houston’s startup network.

Houston ranks among the world’s top 50 startup cities on a new list from PitchBook, a provider of data and research about capital markets. In fact, Houston comes in at No. 50 in the ranking. But if you dig deeper into the data, Houston comes out on top in one key category.

The city earns a growth score of 63.8 out of 100 — the highest growth score of any U.S. city and the seventh highest growth score in the world. In the growth bucket, Houston sits between between Paris (64.4) and Washington, D.C. (61.7).

The PitchBook growth score reflects short-term, midterm, and long-term growth momentum for activity surrounding venture capital deals, exits, and fundraising for the past six years.

PitchBook’s highest growth score (86.5) goes to Hefei, a Chinese manufacturing hub for electric vehicles, solar panels, liquid crystal displays, home appliances, and Lenovo computers.

The overall ranking is based on a scoring system that relies on proprietary PitchBook data about private companies. The system’s growth and development scores are based on data related to deals, exits, fundraising and other factors.

Houston earns a development score of 34.1 out of 100, which puts it in 50th place globally in that regard. This score measures the size and maturity of a city’s startup network.

Topping the overall list is San Francisco, followed by New York City and Beijing. Elsewhere in Texas, Austin appears at No. 16 and Dallas at No. 36.

The ranking “helps founders, operators, and investors assess locations when deciding where to expand or invest,” says PitchBook.

“Network effects matter in venture capital: Investors get more than half of their deals through referrals, according to research led by Harvard professor Paul Gompers,” PitchBook goes on to say. “So it stands to reason that dealmakers should seek these networks out when deciding where to do business.”

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