Over $1.4M in prizes awarded at Rice University's student startup competition

RBPC 2021

Auburn University's SwiftSku took first place in this year's virtually held Rice Business Plan Competition, but it was the second place company that went home with over half a million in cash and investment prizes. Photo via rice.edu

In its 21st year, the Rice Business Plan Competition hosted 54 student-founded startups from all over the world — its largest batch of companies to date — and doled out over $1.4 million in cash and investment prizes at the week-long virtual competition.

RBPC, which is put on by the Rice Alliance for Technology and Entrepreneurship, took place Tuesday, April 6, to Friday, April 9 this year. Just like 2020, RBPC was virtually held. The competition announced the 54 participating startups last month, and coordinated the annual elevator pitches, a semi-finals round, wildcard round and live final pitches. The contestants also received virtual networking and mentoring.

Earlier this week, Rice Alliance announced the seven student-led startups that then competed in the finals. From this pack, the judges awarded the top prizes. Here's how the finalists placed and what won:

SwiftSku from Auburn University, point of sales technology for convenience stores that allows for real time analytics, won first place and claimed the $350,000 grand prize from Goose Capital. The company also won the $50,000 Business Angel Minority Association Prize, the $500 Best Digital Elevator Pitch Prize from Mercury Fund, and the $500 Third Place Anbarci Family People's Choice prize, bringing the company's grand total in cash and investment prizes to $401,000. The company also won the CFO Consulting Prize, a $25,000 in-kind award.
AgZen from the Massachusetts Institute of Technology, a pesticide alternative spray and formulation technology company, won the second place $100,000 investment prize (awarded by Finger Interests, Anderson Family Fund, Greg Novak, and Tracy Druce). The startup also won a $300,000 Owl Investment Prize, the $100,000 Houston Angel Network Prize, the $500 Best Energy Elevator Pitch Prize from Mercury Fund, and the $1,500 Third Place Anbarci Family People's Choice prize, bringing the company's grand total in cash and investment prizes to $502,000. The company also won the $30,000 in-kind Polsinelli Energy Prize.
FibreCoat GmbH from RWTH Aachen University, a startup with patented spinning technology for the production of inexpensive high-performance composite fibers, won the third place $50,000 investment prize (also awarded by Finger Interests, Anderson Family Fund, Greg Novak, and Tracy Druce). The company also won the $100,000 TiE Houston Angels Prize and the $500 Best Hard Tech Elevator Pitch Prize from Mercury Fund, bringing the company's grand total in cash and investment prizes to $150,500.
Candelytics from Harvard University, a startup building the digital infrastructure for 3-D data, won the fourth place $5,000 prize.
OYA FEMTECH Apparel from UCLA, an athletic wear company that designs feminine health-focused clothing, won the fifth place $5,000 prize. The company also won the $5,000 Eagle Investors Prize, the $25,000 Urban Capital Network Prize, and the $1,000 Second Place Anbarci Family People's Choice prize, bringing the company's grand total in cash and investment prizes to $36,000.
LFAnt Medical from McGill University , an innovative and tech-backed STI testing company, won the sixth place $5,000 prize and the $20,000 Johnson and Johnson Innovation Prize, bringing the company's grand total in cash and investment prizes to $25,000.
SimpL from the University of Pittsburgh, an AI-backed fitness software company, won the seventh place $5,000 prize. The company also won the $25,000 Spirit of Entrepreneurship Prize from the Pearland Economic Development Corp., bringing the company's grand total in cash and investment prizes to $30,000.

Some of the competition's participating startups outside of the seven finalists won monetary and in-kind prizes. Here's a list of those.

Mercury Fund's Elevator Pitch Prizes also included:
- Best Life Science $500 Prize to Blue Comet Medical Solutions from Northwestern University
- Best Consumer $500 Prize to EasyFlo from the University of New Mexico
- Best Overall $1,000 prize to Anthro Energy from Stanford University
The Palo Alto Software Outstanding LivePlan Pitch $3,000 Prize went to LiRA Inc. from the University of North Carolina at Chapel Hill
The OFW Law FDA Regulatory Strategy Prize, a $20,000 in-kind award went to Paldara Inc. from Oklahoma State University.
The Silver Fox Mentoring Prize, which included $20,000 in kind prizes to three winners selected Ai-Ris from Texas A&M University, BruxAway from the University of Texas, and Karkinex from Rice University as recipients.
The first, second, and third place winners also each received the legal service prize from Baker Botts for a total of $20,000 in-kind award.
The Courageous Women Entrepreneurship Prize from nCourage — a $50,000 investment prize — went to Shelly Xu Design from Harvard University.
The SWPDC Pediatric Device Prize — usually a $50,000 investment divided its prize to two winners to receive $25,000 each
- Blue Comet Medical Solutions from Northwestern University
- Neurava from Purdue University
TMC Innovation Healthcare Prize awarded a $100,000 investment prize and admission into its accelerator to ArchGuard from Duke University
The Artemis Fund awarded its $100,000 investment prize to Kit Switch from Stanford University

The awards program concluded with a plan to host the 22nd annual awards in 2022 in person.

If you missed the virtual programming, each event was hosted live on YouTube and the videos are now available on the Rice Alliance's page.

In the latest round up of Houston innovation news you may have missed, applications open for Houston accelerators, Greentown Labs has a grand opening date, and more. Photo via Getty Images

Greentown Houston announces grand opening, clean energy accelerators open apps, and more innovation news

short stories

It's been a crazy start to 2021 with the innovation ecosystem being especially busy. For this reason, Houston innovation news may have fallen through some of the cracks.

In this roundup of short stories within Houston innovation, Greentown Labs makes a big announcement, new accelerator programs open applications, a UH-born technology wins big, and more.

Greentown Labs announces grand opening for Houston location

Greentown Houston is opening next month. Photo via GreentownLabs.com

Last Earth Day, the City of Houston launched its first Climate Action Plan. This Earth Day, the Greentown Houston is opening its doors. On Thursday, April 22, from 2 to 3:30 pm, Greentown Labs is hosting a virtual event to mark the grand opening.

At the event, attendees will be able to meet startups that are a part of the program, hear from energy and civic leaders, catch the latest Greentown partners, and watch the building's ribbon cutting. The event is free and registration is open.

"Greentown Houston is our first out-of-state expansion, and we have already welcomed more than 20 startup members and more than 20 Founding and Grand Opening partners," reads a recent announcement from Greentown. "Located in the city's Innovation District, Greentown Houston will provide more than 40,000 sq. ft. of prototyping lab, office, and community space for about 50 climatetech startups, totaling 200-300 employees."

Rice Alliance opens applications for its clean energy accelerator program

The Rice Alliance Clean Energy Accelerator's inaugural cohort will be held virtually — but will eventually be housed in The Ion. Courtesy of Rice University

The Rice Alliance for Technology and Entrepreneurship has opened applications for its inaugural cohort for the recently announced Clean Energy Accelerator. The program will be held virtually this summer from June to September — but will eventually be hosted out of The Ion.

At the conclusion of the program, the cohort will present in a Demo Day in conjunction with the 19th annual Rice Alliance Energy Venture Forum.

Applications are due by April 14 and interested parties can apply online.

University of Houston-born innovation wins big at SXSW

A UH-born device won a $25,000 investment at a SXSW event. Photo via UH.edu

A University of Houston professor took home an innovation prize and $25,000 investment from the Southwest National Pediatric Device Innovation Consortium's Pediatric Device Prize at this year's SXSW. The UH-born device is the Pediatric Lower-Extremity Gait System – known as P-LEGS – which is a mobility assistant, rehabilitation platform and diagnostic tool designed to help children with motor disabilities. It won one of two prizes out of 18 devices.

The principal investigator for the project, Jose Luis Contreras-Vidal, is a Hugh Roy and Lillie Cullen Distinguished Professor of Electrical and Computer Engineering and the director of UH's BRAIN Center. Other team members include graduate student lead, David Eguren, as well as Alexander Steele, Yang Hu, Krishna Sarvani Desabhotla, Swagat Bhandari, Lujayna Taha, Nivriti Sabhnani, and Allen Shen.

"We were excited and honored to have been selected by the SWPDC for this award," Eguren says in a news release. "The award will be valuable in helping us continue device development and testing."

Halliburton Labs opens next round of applications

Halliburton Labs is looking for its next cohort. Photo courtesy of Halliburton

A new corporate accelerator has announced that its latest round of startup applications is open. Halliburton Labs looking for startups for its next cohort, and applications are due on April 23.

"We're excited to identify technology entrepreneurs with ready-to-scale solutions in energy generation, storage, distribution, conservation, and the circular economy," says Dale Winger, managing director of Halliburton Labs, in a news release. "Our program provides critical resources, including technical and operational expertise across numerous hardware disciplines and a global business network, to help participants advance their products, prepare for further scale and position for additional financing."

Halliburton Labs will make their selections by the ongoing program's pitch day, which is slated for May 21. The Halliburton Labs Finalist Pitch Day will be a part of the Houston Tech Rodeo.

To apply to participate, click here.

Innovative organization names new board members

Baylor College of Medicine-supported, and NASA-backed TRISH has new board members. Photo via NASA/JPL-Caltech

The Translational Research Institute for Space Health — known as TRISH — recently announced seven new members to its Scientific Advisory Board. The Houston-based, NASA-funded organization is focused on cultivating space health innovations.

"We are at the cusp of space becoming more accessible to regular people. We are working toward safeguarding the health of all humans -- astronauts exploring deep space and people with preexisting conditions that want to experience space for short periods," says TRISH Director Dorit Donoviel. "TRISH's diverse advisory board members will help us focus our resources on the most impactful health technology and science innovations."

According to a press release, the newly appointed members are:

Col. Catherine Coleman, Ph.D., is a former NASA Astronaut and the Global Explorer in Residence at Arizona State University and Research Affiliate at the MIT Media Lab.
Asha Collins, Ph.D., is the U.S. Country Head for Country Clinical Operations at Genentech.
Armen Kherlopian, Ph.D., is a founding partner of BAJ Accelerator.
Manish Kothari, Ph.D., is the President of SRI International.
Nicole Stott, M.S., is a former NASA Astronaut and the Founding Director of the Space for Art Foundation.
Matthew Wagoner, Ph.D., leads Investigative Toxicology at Takeda Pharmaceuticals.
Brian Zambrowicz, Ph.D., is Senior Vice President of Regeneron Pharmaceuticals.

They join existing members:

Board Chair Lisa Suennen, M.A., is the leader of Manatt Digital and Technology and the firm's related consulting practice.
Imran Alibhai, Ph.D., is the Chief Executive Officer of Tvardi Therapeutics.
Susan Alpert, M.D., Ph.D., is the Founder and Principal of SFA Consulting, LLC
Catherine M. Davis-Takacs, Ph.D., is an Assistant Professor at the Uniformed Services University of the Health Sciences.
Seth Feuerstein, M.D., J.D., is a faculty adviser in innovation and entrepreneurship and Assistant Clinical Professor of Psychiatry at the Yale University Center for Biomedical and Interventional Technology
Daniel Lowenstein, M.D., is the Executive Vice Chancellor and Provost of the University of California San Francisco.
Ted Smith, Ph.D., is an Associate Professor of Pharmacology and Toxicology and Director of the Center for Healthy Air, Water and Soil at the Christina Lee Brown Envirome Institute of University of Louisville School of Medicine.
Maj. Gen. Annette L. Sobel, M.D., M.S., is an Adjunct Professor in the Texas Tech University Health Sciences Center's Schools of Nursing and Texas Tech University's Department of Electrical and Computer Engineering.

Here's what not to miss at the first all-virtual CERAWeek by IHS Markit. Screenshot via virtual.ceraweek.com

5 can't-miss innovation events at CERAWeek featuring Houston speakers

where to be online

While usually hundreds of energy experts, C-level executives, diplomats, members of royal families, and more descend upon Houston for the the annual CERAWeek by IHS Markit conference, this year will be a little different. Canceled last year due to COVID-19, CERAWeek is returning — completely virtually.

The Agora track is back and focused on innovation within the energy sector. The Agora track's events — thought-provoking panels, intimate pods, and corporate-hosted "houses" — can be accessed through a virtual atrium.

Undoubtedly, many of the panels will have Houston representatives considering Houston's dominance in the industry, but here are five innovation-focused events you can't miss during CERAWeek that feature Houstonians.

Monday — New Horizons for Energy & Climate Research

The COVID-19 pandemic has made vivid and real the risks of an uncontrolled virus. Risks posed by climate change are also becoming more palpable every day. At the forefront of understanding these risks, universities are developing solutions by connecting science, engineering, business, and public policy disciplines. Along with industry and governments, universities are critical to developing affordable and sustainable solutions to meet the world's energy needs and achieve net-zero emission goals. Can the dual challenge of more energy and lower emissions be met? What is some of the most promising energy and climate research at universities? Beyond research, what are the roles and responsibilities of universities in the energy transition?

Featuring: Kenneth B. Medlock, III, James A. Baker, III, and Susan G. Baker Fellow In Energy And Resource Economics, Baker Institute and Senior Director, Center For Energy Studies at Rice University

Catch the panel at 1 pm on Monday, March 1. Learn more.

Tuesday — Conversations in Cleantech: Powering the energy transition

With renewables investment outperforming oil and gas investment for the first time ever in the middle of a pandemic, 2020 was a tipping point in the Energy Transition. Low oil prices intensified energy majors' attention on diversification and expansion into mature and emerging clean technologies such as battery storage, low-carbon hydrogen, and carbon removal technologies. Yet, the magnitude of the Energy Transition challenge requires an acceleration of strategic decisions on the technologies needed to make it happen, policy frameworks to promote public-private partnerships, and innovative investment schemes.

Three Cleantech leaders share their challenges, successes, and lessons learned at the forefront of the Energy Transition. What is their vision and strategy to accelerate lowering emissions and confronting climate change? Can companies develop clear strategies for cleantech investments that balance sustainability goals and corporate returns? What is the value of increasing leadership diversity for energy corporations? Can the Energy Transition be truly transformational without an inclusive workforce and a diverse leadership?

Featuring: Emily Reichert, CEO of Greentown Labs, which is opening a location in Houston this year.

The event takes place at 11:30 am on Tuesday, March 2. Learn more.

Wednesday — Rice Alliance Venture Day at CERAWeek

The Rice Alliance for Technology and Entrepreneurship pitch event will showcase 20 technology companies with new solutions for the energy industry. Each presentation will be followed by questions from a panel of industry experts.

Presenting Companies: Acoustic Wells, ALLY ENERGY, Bluefield Technologies, Cemvita Factory, Connectus Global, Damorphe, Ovopod Ltd., DrillDocs, GreenFire Energy, inerG, Locus Bio-Energy Solutions, Nesh, Pythias Analytics, REVOLUTION Turbine Technologies, Revterra, ROCSOLE, Senslytics, Subsea Micropiles, Syzygy Plasmonics, Transitional Energy, and Universal Subsea.

The event takes place at 9 am on Wednesday, March 3. Learn more.

Thursday — How Will the Energy Innovation Ecosystem Evolve?

Although the cleantech innovation ecosystem—research institutions, entrepreneurs, financiers, and support institutions—is diverse and productive, converting cleantech discoveries and research breakthroughs into commercially viable, transformative energy systems has proven difficult. With incumbent energy systems economically efficient and deeply entrenched, cleantech innovation faces a fundamental dilemma—the scale economies necessary to compete require a large customer base that does not yet exist. How is our clean energy innovation ecosystem equipped to be transformative? What needs to be strengthened? Is it profitable to focus on individual elements, or should we consider the system holistically, and reframe our expectations?

Featuring: Barbara Burger, vice president of innovation at Chevron and president at Chevron Technology Ventures

The event takes place at 7:30 am on Thursday, March 4. Learn more.

Friday — Cities: Managing crises & the future of energy

Houston is the capital of global energy and for the past four decades the home of CERAWeek. Mayor Sylvester Turner will share lessons from the city's experience with the pandemic, discuss leadership strategies during times of crisis, and explore Houston's evolving role in the new map of energy.

The event takes place at 8 am on Friday, March 5. Learn more.

Christine Galib and Courtney Cogdill of The Ion join the Houston Innovators Podcast to discuss the four accelerator programs that are striving to advance Houston. Photos courtesy of The Ion

The Ion's accelerators are working to bring out the best in Houston — from resiliency to diversity

HOUSTON INNOVATORS PODCAST EPISODE 71

When you look at the business accelerator programs offered at The Ion, a rising innovation hub in Midtown, you see Houston represented. From energy and space tech to resiliency and diversity, the four accelerators intentionally cover what Houston is all about.

Courtney Cogdill, program director of the Accelerator Hub, and Christine Galib, senior director, at The Ion joined the Houston Innovators Podcast to discuss what all they are focused on across the business accelerator programs at the hub. Editor's note: This podcast was recorded ahead of the winter storm that affected the state of Texas this week.

Now more than ever, innovators are dedicating their careers to resilient technologies that can enhance the city's future. And this effort comes naturally to Houstonians, Galib says on the podcast.

"There is an ethos here that is one of roll up your sleeves, collaborate, and get to work. Get the work done, and have fun while you're doing it," she says on the show. "We all come together in a time of challenge, and we really show each other that we're not just individually resilient, we are collectively resilient."

Neither Galib nor Cogdill are from Houston — but each have observed the same resiliency among the city and its people.

"Houston really just picks itself back up by the bootstraps and just runs," Cogdill says.

But The Ion Smart and Resilient Cities Accelerator, launched in 2019, was only just the beginning for The Ion's Accelerator Hub. Last year, three more accelerator programs were announced — the Aerospace Innovation Hub for Minority Business Enterprises at The Ion, Austin-based DivInc's Accelerator, and the Rice Alliance Clean Energy Accelerator. These were made possible through a series of grants — a $1.4 million one from NASA to launch the ASCI-Hub and a $1.5 million one from Economic Development Administration.

Galib and Cogdill discuss each of the programs, as well as what they are excited for when The Ion opens later this year. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

Houston — known as the Energy Capital of the World — had several trending stories in 2020 focused on energy innovation. Photo via Getty Images

Houston organization names 10 most promising life sciences startups

ones to watch

Last week, the Rice Alliance for Technology and Entrepreneurship gathered over 1,000 life science experts and attendees virtually for thought leadership as well as 40 company presentations.

The three-day 2020 Virtual Texas Life Science Forum was made possible through a partnership with BioHouston and support from Texas Medical Center and Insperity. At the close of the summit, several companies were recognized with awards.

Houston-based Starling Medical won the Michael E. DeBakey Memorial Life Science Award, established by BioHouston in honor of the groundbreaking Houston cardiovascular surgeon. The digital health device company is revolutionizing severe bladder dysfunction management with artificial intelligence.

Every year at the forum, the Rice Alliance names its 10 most promising companies working on developing innovative solutions in medical devices, digital health, diagnostics, pharmaceuticals, and therapeutics. This year, Brad Burke, managing director of the Rice Alliance, says they had more applications to present than ever before. Additionally, the presenting companies — about half of which are Houston-based — have already raised more than $275 million in funding.

The 2020 most-promising life science companies, which were chosen by investors and presented by the Greater Houston Partnership, were:

Droice Labs

Image via droicelabs.com

New York-based Droice Labs, is an artificial intelligence and big data company matches patients to therapies and delivers personalized medicine at scale while reducing costs.

"Our cutting-edge technology seamlessly integrates into clinical workflows, and we continue to evolve unique and powerful applications for our clients and the patients they serve," reads the company's website.

SFA Therapeutics

Image via sfatherapeutics.com

Based in Jenkintown, Pennsylvania, SFA Therapeutics is developing oral drugs for treating conditions of chronic inflammation that have the potential to change the practice of medicine. The company has treatments for Psoriasis, Liver Cancer (Hepatitis B, NASH and HCC), Ophthalmic Diseases, Cytokine Release Syndrome- a side effect in CAR-T, Prevention of Relapse/Recurrence in Leukemias, and other diseases.

Hummingbird Bioscience

Photo via jlabs.jnjinnovation.com

Hummingbird Bioscience, based in Houston's JLABS @ TMC, is tackling challenging targets that play a key role in disease yet have not been effectively drugged. The company has worked on 12 therapies in various stages of development, four of which have the potential to revolutionize their fields.

"At Hummingbird, we believe that modern approaches to systems biology and data science can overcome the challenges of classical methods of therapeutics discovery, and profoundly improve the way we deliver new transformative medicines," reads the company website.

CaseCTRL

Image via casectrl.com

Houston-based CaseCTRL is empowering surgeons with a management platform with software-as-a-service technology that uses AI and logistics to lower operational costs and simplify surgical planning.

"The surgical scheduling process is frustratingly stuck in the past: siloed, paper-based, and too dependent on single schedulers," reads the website. "Surgeons are stressed and overworked. They need a better way to communicate their complex surgical plans, timelines and resource needs."

Perimeter Medical

Image via perimetermed.com

Perimeter Medical, based in Dallas, is driven to transform cancer surgery with advanced, real-time, ultra high-resolution imaging tools including AI to address areas of unmet medical need.

"Perimeter is dedicated to providing solutions that drive better patient care and lower healthcare costs by providing critical information, during clinical procedures," reads the website.

Studio Bahria

Image via studiobahia.org

San Antonio-based Studio Bahia, is developing an accessible model for therapy in addressing mental health crises from the pandemic through virtual reality.

"We are in production of our first two therapies for release in the 4th quarter of 2020. Studio Bahia clients include corporate, retail, and institutional partners who purchase our headsets for $25 in providing mental health therapies and wellness tools to employees, executives, and patients," reads the company's website.

Tvardi Therapeutics

Photo via Getty Images

Tvardi Therapeutics, based in Houston, is a clinical-stage biopharmaceutical company focused on the development of a new class of breakthrough medicines for diverse cancers and chronic inflammatory and fibrotic diseases.

"Tvardi is focused on the development of orally delivered, small molecule inhibitors of STAT3, a key signaling molecule positioned at the intersection of many disease pathways," reads the website.

Koda Health

Image via kodahealthcare.com

Koda Health, Houston, uses AI to help guide difficult conversations in health care, starting with end-of-life care planning.

"You're entitled to protect the healthcare decisions that matter most to you and your family," the company's website promises. "Koda creates Care Plans to ensure that you get the medical care you want."

Immuno Genesis

Photo via Getty Images

Houston-based ImmunoGenesis is a clinical-stage biotechnology company developing therapeutics to catalyze effective immune responses in immunologically "cold" cancers such as prostate, colorectal, and pancreatic.

"Compared to existing immunotherapy drugs, we believe this antibody will both provide more consistent benefit for patients with immune-infiltrated tumors, and, for the first time, will also benefit patients with immune 'cold' cancers," says founder Dr. Michael A. Curran in a press release announcing the company's grant from the Cancer Prevention and Research Institute of Texas.

Ictero Medical

Image via Getty Images

Ictero Medical, based in Houston, is developing the first minimally invasive cryoablation solution to treat patients with gallstone disease. Ictero Medical has created a minimally invasive treatment, called The CholeSafe System, that uses cryoablation to defunctionize the gallbladder without having to remove it.

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Exclusive: Houston coworking company to open sports tech-focused hub

go team

It's game time for a Houston-based coworking company that's working on opening a sports innovation hub this summer.

The Cannon is working on opening new hub in 53 West, a Galleria-area office building recently renovated by Braun Enterprises. The project is in partnership with Gow Media, InnovationMap's parent company, and will be co-located with the media business that runs Gow Broadcasting LLC and the SportsMap Radio Network, which includes local sports station 97.5 as well as national syndicated content.

The Cannon's founder Lawson Gow tells InnovationMap that Gow Media — founded by Lawson's father, David Gow — and Braun Enterprises were opportunistic partners for the organization.

"We've always been optimistically looking for strategic partners that we can co-locate with or team up with to create a hyper focused, niche community," Lawson Gow says. "We've spent a lot of time thinking about what that can be."

Expected to open midsummer, the new two-story space will have 23 offices and a 1,500-square-foot open space that can be used for events. All existing Cannon members will have access to the space, and potential tenants can expect a similar pricing model to The Cannon's other three Houston-area locations.

Houston makes sense for sports tech, which Gow defines as encompassing four categories of innovation — fan engagement, activity and performance, fantasy and gambling, and esports. Houston has the money, the big four sports teams, a big fan base, and corporate interest, he explains.

"Sports tech is a thing we can win at. There's no global hub for sports tech — so Houston can do that," Gow says. "We've always had that in our heads as a direction we want the city to head down, so it just makes it so opportunistic to create a space for that kind of innovation at work for the city."

53 West has been undergoing renovations recently. Photo via braunenterprises.com

Houston-based cancer and disease bio-venture launches after multimillion dollar series A

money moves

Sporos Bioventures LLC launched this month after closing a $38.1 million round of series A financing.

The Houston-based biotech company aims to accelerate the development of breakthrough therapies for cancer and immune diseases by sharing resources, capital, access to clinical trial infrastructure, and talent from within its knowledgeable team of biotech executives, entrepreneurs, academic scholars, and investors. The company was launched with four entities: Tvardi Therapeutics, Asylia Therapeutics, Nirogy Therapeutics, and Stellanova Therapeutics.

The most advanced of the four entities, Tvardi, is currently in Phase 1 clinical trial to evaluate it's STAT3 oral inhibitor. It was named a "most promising" life sciences company at the 2020 Texas Life Science Forum, hosted by BioHouston and the Rice Alliance in December. The remaining entities are in the development stages and are focused on cancer, autoimmune disease, fibrosis, and tumor growth, among other conditions.

"Sporos was founded to accelerate the development of new medicines by addressing inefficiencies and risk in the establishment of new biotech companies," Peter Feinberg, Sporos co-founder, said in a statement. "By leveraging our extensive network, including the Texas Medical Center, we first identify transformative scientific opportunities and then deploy our top-tier talent, funding, and operational support to drive these insights into a growing pipeline of first-in-class treatment options."

In conjunction with the launch, Sporos named Michael Wyzga as the company's founding CFO. Wyzga was previously CFO at Genzyme for 12 years and has held various senior-level positions in the industry.

"By strategically deploying valuable resources to young companies that would not typically be supported by top-tier seasoned talent and infrastructure, we believe that we can efficiently bring a diverse set of therapies through clinical development," Wyzga said in a statement. "I am thrilled to join a team with decades of scientific and operational expertise and look forward to guiding our strategic and financial growth."

Wyzga joins a team of seasoned leaders in the biotech and cancer research fields, including Dr. Ronald DePinho, professor of Cancer Biology and past president of MD Anderson, who will serve as the chair of Sporos' Strategic Advisory Council. Jeno Gyuris, a biotech executive in oncology drug discovery and development with more than 25 years of experience, will serve as chief science officer. And Alex Cranberg, an experienced active early-stage biotech investor, serves as director.

To expand or not to expand? Houston researcher weighs in on global growth

houston voices

You built your business from the ground up, patiently finding techniques and products that work, carefully crafting solid bonds with your clients. Then one day a new project, opportunity or simple request poses a question: Is it time to branch out overseas?

Of the welter of questions to consider, the first and most important involves location: not just the physical location of the prospective expansion site, but the cultural differences between a firm's home country and its new destination. Secondly, key company traits need to be considered in choosing the investment locations. Is your firm large or small? Young or old? Finally, of pivotal importance to companies outside the United States: Is your company privately held or state-owned?

In a recent paper, Rice Business professor Yan Anthea Zhang looked closely at these three variables with Yu Li of the University of International Business and Economics Business School in Beijing, China and Wei Shi of the Miami Business School at the University of Miami. What, the researchers wanted to know, was the relation of these three features and firms' location choices for their overseas investments?

To find out, Zhang and her colleagues analyzed 7,491 Chinese firms that had recently ventured into foreign markets with 9,558 overseas subsidiaries. Because China now has become the world's leading source of foreign direct investments, the sample promised to be instructive. Thanks to the large sample size, researchers could test hypotheses relating to firm size, age, ownership and the impact of geographical and cultural distance on their location choices.

After studying the elements of geographic distance and cultural distance, Zhang and her colleagues uncovered a paradox. Companies that had an advantage in tackling one dimension of distance were actually disadvantaged — because of the same characteristic — in another dimension.

How, exactly, did this paradox work? Larger firms, with access to more resources, can "experiment with new strategies, new products, and new markets," the researchers wrote. This large size makes geographic distance less of a concern, but it comes with a ponderous burden of its own. Company culture is directly influenced by the country of origin, Zhang wrote. Transferring that culture into a completely different environment can cause the kind of shock that could lead to failure, even with financial and physical resources to ease the geographical distance. Conversely, smaller firms may be more nimble and able to adapt to needed cultural changes — but lack the resources to make true inroads in a foreign market.

A similar paradox exists for older and younger firms, Zhang wrote. A younger firm is more likely to adapt to a culturally distant country than an older firm might, even if that youth means that geographical distance is a greater logistical challenge.

State-owned firms face a similar paradox, one that comes down to the balance of resources against cultural flexibility. A company with state-generated resources may be better equipped to move a caravan people, machinery and materials to a distant new location. However, state-owned companies often typically lack the internal cultural flexibility to handle expansion to a different environment.

What does this mean for the average manager? Simply that going global demands meticulous weighing of factors. Does your firm have the practical resources to expand overseas? Does your staff have the personal flexibility and willingness to meld company culture with that of a different milieu? It's a truism that major overseas expansions require money and heavy lifting. Less obviously, managers of successful companies must thread a very fine needle: ensuring they have the material resources to get their business overseas physically, while confirming that company culture is light enough on its feet to thrive in day-to-day life in a new place.

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This article originally ran on Rice Business Wisdom and is based on research from Yan Anthea Zhang, a professor and the Fayez Sarofim Vanguard Chair of Strategy in the Jones Graduate School of Business at Rice University.

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