Practice makes perfect

Houston company is using 3D printing to enhance surgeon training and prevent avoidable patient deaths

Lazarus 3D is using 3D printing to help advance surgeons' skills. Photo via laz3d.com

It is no surprise that, when a company offered life-like bladders for medical training, Houston urologists jumped at the opportunity — many had to learn the surgery by operating on bell peppers.

This sort of produce practice is the traditional method for teaching surgeons. Before a doctor ever makes an incision on a living person, they'll practice surgery on food — slicing bananas open and sewing grapes back together.

But for a pair of Baylor College of Medicine-educated doctors, that didn't seem like sufficient prep for working with living bodies; fruit surgery was not fruitful enough. In 2014, Drs. Jacques Zaneveld and Smriti Agrawal Zaneveld founded Lazarus3D to build a better training model — and layer by layer, they created models of abs and ribs and even hearts with a 3D printer.

"We adapted pre-existing 3D printing technology in a novel proprietary way that allows us to, overnight, build soft, silicone or hydrogel models of human anatomy," says Jacques, who serves as CEO. "They can be treated just like real tissue."

This isn't 3D printing's foray in medicine. In 1999, doctors in North Carolina implanted the first 3D-printed bladder in human bodies — they covered the synthetic organs in the patients' cells so that their bodies accepted them. Since, researchers have continued to find uses for the technology in the field, printing other organs and making prosthetic limbs.

But the Lazarus3D founders felt like medical training was lagging behind. Even cadavers, which medical schools also use to prepare doctors for surgery, don't represent a healthy human body or the diseased state of a hospital patient, said Smriti, who works as the research director.

The pair turned their kitchen into a printing lab and set to work, creating life-like models of human organs. They didn't have to go far after their first successes to find potential buyers — they just went to Starbucks. In a coffeeshop in the heart of the Medical Center, they talked loudly about their product until the neighborhood doctors and researchers took interest and gathered around.

Over the next few years, the Lazarus3D team pooled resources and contacts and, a summer after opening, they moved out of their kitchen and into an office. They now are a Capital Factory portfolio company and have partnerships with Texas Children's, Baylor College of Medicine, MD Anderson Cancer Center, and others, providing organs for specialized training — and the more they expand, the more they're able to prepare doctors for invasive, sometimes dangerous procedures.

"There are over 400,000 deaths annually in the U.S. due to medical error," Smriti says. "Not all of them are due to surgical mistakes, but all of these, nonetheless, were preventable."

The models can also be used for explaining to patients in a visual way what surgeries they're about to receive — the black and grey smears on an MRI scan might not actually help a patient understand much about what a surgeon is going to do to their body. In 2018, Lazarus3D won a contest with NASA on the potential for 3D printing organs in space, so that major surgeries might be performed there. And the printed organs can also be used by researchers to safely develop new surgery methods.

This year, the company grew to seven people and aims to expand even more to add to its sales and manufacturing teams. Having been funded mostly by friends and family investors, Lazarus3D plans enter its first equity round this year. They're raising $6 million.

"Every generation in medicine, people look back at what was done before and think 'Man, that was barbaric,'" Jacques said. "Fifty years from now, we're going to look back and think, 'Man, back then we used to just give someone a patient to learn how to do physical skills on? That seems crazy.'"

UH's business school has been recognized for innovation and entrepreneurship. Photo via bauerticker.uh.edu

Hitting headlines this month are innovation news stories from sustainability and education to funding and startup competitions.

In this innovation news roundup, two health-focused startups raise money, the University of Houston earns two pats on the back, a Houston-based former WeWork exec joined the C-suite of a sustainable clothing company, and more.

BrainCheck closes $8 million seed round

BrainCheck has received funding to grow its cognitive assessment platform. Photo via braincheck.com

Houston-based BrainCheck, a cognitive health tech platform closed its $8 million series A funding round. Austin-based S3 Ventures and Chicago-based Tensility Venture Partners co-led the round, and Austin-based True Wealth Ventures and Kansas-based Nueterra Capital also contributed to the round.

BrainCheck's digital platform allows physicians to better assess cognitive function in their patients. The new funds will be used for research and development, including customizing the platform's algorithm for an enhanced patient experience, according to a news release.

"Cognitive healthcare should be an end-to-end solution where problems can be assessed early, and results shared between patients and physicians," says Dr. Yael Katz, co-founder and CEO of BrainCheck, in the release. "By analyzing multiple forms of data, BrainCheck helps physicians create and fine tune personalized interventions. This not only improves outcomes for current patients, but is invaluable to developing management and treatment strategies for future generations."

Former WeWork exec Emily Keeton joins C-suite of a sustainable clothing startup

Goodfair has created a digital thrifting platform. Photo via goodfair.com

After a little over two years at WeWork in leadership positions, Emily Keeton has left the coworking space company to join a Houston startup. Keeton, who was among the founders of Station Houston, is now the chief operating officer at Goodfair, a direct-to-consumer thrift platform based in Houston.

"The rise of fast fashion is contributing to major environmental change," she tells InnovationMap. "Right now, the average American buys 68 new garments a year and wears each one only 7 times. Clothing production is responsible for over 20 percent of all industrial water pollution."

Keeton says she was connected with Goodfair's CEO, Topper Luciani, through the company's lead investor, Paul Bricault of California-based Amplify. Luciani just moved to Houston, and the company also has a warehouse here.

Goodfair sells bundles of "pre-loved" clothes based on size and category at a low price point.

"You know you'll get a medium flannel shirt, but you don't know exactly what color. If you don't like it, you can get a new order for the cost of shipping only," Keeton says. "We have created an entirely new model for this industry, which is an over $14 billion market."

NurseDash raises bridge round as the startup braces for growth

Houston-based NurseDash is the Uber of staffing nursing shifts in medical facilities. Photo via nursedash.com

A growing Houston startup has received bridge funding ahead of opening a larger round. NurseDash, a digital staffing tool for nurses and medical facilities, has received $500,000 from East Coast-based SEI Ventures.

The corporate-backed fund has contributed greatly to higher education institutions, like Capella University, which has a large nursing program.

"Some of the ways we think we can help NurseDash accelerate their growth is getting getting word out to Capella's tens of thousands of alumni and hundreds of employer partners to make sure they are aware of the advantages of the platform, and potentially organizing an educational partnership as well," Taylor Chapman, Houston native and principal at SEI Ventures, tells InnovationMap.

NurseDash, which launched in 2017, now has a presence in 80 facilities on the platform and over 1,000 clinician users in Houston, Austin, and Northeast Ohio.

"We are excited to have SEI join us as a strategic investor and the opportunity that it brings for us to provide enhanced educational opportunities to our clinicians as well as greater exposure the wonderfully talented group that comprises the alumni and nursing students of Cappella University," says CEO and Co-founder Jake Kohl in an email.

University of Houston programs receive recognition

The University of Houston's business school has been recognized for two of its programs. Photo courtesy of University of Houston

The University of Houston's business school has two more feathers to add to its cap.

Bloomberg BusinessWeek named the MBA program at the C. T. Bauer College of Business as among the world's best programs for entrepreneurs. The program tied for ninth in the B- category out of 126 programs surveyed.

"Bauer students indeed reflect the values of our beloved Houston," Professional Programs Associate Dean Leiser Silva says in a news release. "Like our city, they have grit, they are resilient, and they are the bearers of an unparalleled ingenuity. It is in their character to assume calculated risks and be entrepreneurs."

Meanwhile, Bauer's Stimulating Urban Renewal through Entrepreneurship received the 2019 Award of Excellence for Innovation + Talent at the recent University Economic Development Association annual summit. The program creates a partnership between UH students and local entrepreneurs and area business leaders.

"At the heart of the program is experiential learning for our students, along with a commitment to service and civic engagement," says SURE™ founder and director Saleha Khumawala, in a news release.

Capital Factory seeks Texas companies for artificial intelligence challenge

blockchain

Capital Factory is looking for AI companies to compete for $100,000. Getty Images

Austin-based Capital Factory, which has a statewide presence, is looking for startups with artificial intelligence technologies.

The $100,000 Artificial Intelligence Challenge is asking companies to submit their solutions to four key challenges decided by the Army Artificial Intelligence Task Force. The four challenges are: Intelligence support for long-range precision, automated threat recognition for the next-generation combat vehicle, human resources and talent management, and predictive maintenance for military assets.

The competition will conclude on November 12th, at Capital Factory's Defense Innovation Summit. Five technology finalists will be judged by a panel, and one will receive a $100,000 investment that day. The deadline to apply online is October 21.

Work & Mother announces new location

Houston-based Work & Mother is rethinking how new mothers pump in the office. Courtesy of Work & Mother

Houston startup Work & Mother, which runs lactation centers for new moms returning to work, has another location opening. Brookfield Properties announced that Work & Mother has signed a lease for a 949-square-foot space at Three Allen Center at 333 Clay St. in downtown Houston with an expectation top open next summer.

"We are thrilled to partner with Brookfield Properties on this project. We've found that companies aren't equipped to fully address such a private and intimate issue as pumping breast milk in the office," says Abbey Donnell, founder and CEO, in a news release. "It doesn't make sense for every company in a large office tower to take this on individually. Work & Mother is a better economic option for companies in that they reduce their legal risks and create a better working environment, preserving their own office space for their core business."