who's who

4 female Houston innovators to know this week

This week's roundup of Houston innovators includes Dorit Donoviel of TRISH, Anu Pansare of gBETA, and Christine Galib and Courtney Cogdill of The Ion. Courtesy photos

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to four innovators across industries recently making headlines — from space tech to startup development organizations.

Dorit Donoviel, director of the Translational Research Institute for Space Health

NASA has renewed its support for Baylor College of Medicine's Translational Research Institute for Space Health. Libby Neder Photography

Baylor College of Medicine's Translational Research Institute for Space Health, known as TRISH, got the green light on a grant renewal from NASA, which will allow the organization to continue to conduct biomedical research geared at protecting astronauts in deep space through 2028. NASA opted to continue the partnership and now TRISH will receive additional funding of up to $134.6 million from 2022 to 2028.

"NASA has received outstanding value from our bold approach to sourcing and advancing space health research and technologies," institute director Dorit Donoviel, says in a statement. "We are proud to be NASA's partner in its human space exploration mission and to be supporting the research necessary to create new frontiers in healthcare that will benefit all humans." Click here to read more.

Anu Pansare, director of gBETA Houston

Anu Pansare has joined the local gBETA team. Photo via gbetastartups.com

Anu Pansare has a new gig. The Sugar Land-based consultant has over 20 years of experience working with the likes of Chevron, Schlumberger, and Accenture, as well as smaller startups. Pansare, who's also been involved with the Houston Angel Network, recently started as director of gBETA's Houston office.

As the main liaison between Houston and gener8tor's national network, Pansare will lead gBETA's third cohort — for which applications are open online — through its free 7-week program, which is designed to help participating companies gain early customer traction and develop key metrics that will make them more marketable for future investment. Click here to read more.

Christine Galib and Courtney Cogdill of The Ion

Christine Galib and Courtney Cogdill of The Ion join the Houston Innovators Podcast to discuss the four accelerator programs that are striving to advance Houston. Photos courtesy of The Ion

Courtney Cogdill, program director of the Accelerator Hub, and Christine Galib, senior director, at The Ion joined the Houston Innovators Podcast to discuss what all they are focused on across the business accelerator programs at the hub. Now more than ever, innovators are dedicating their careers to resilient technologies that can enhance the city's future. And this effort comes naturally to Houstonians, Galib says on the podcast.

"There is an ethos here that is one of roll up your sleeves, collaborate, and get to work. Get the work done, and have fun while you're doing it," she says on the show. "We all come together in a time of challenge, and we really show each other that we're not just individually resilient, we are collectively resilient." Click here to read more and stream the episode.

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Building Houston

 
 

From a low-cost vaccine to an app that can help reduce exposure, here are the latest COVID-focused and Houston-based research projects. Photo via Getty Images

While it might seem like the COVID-19 pandemic has settled down for the time being, there's plenty of innovative research ongoing to create solutions for affordable vaccines and tech-enabled protection against the spread of the virus.

Some of that research is happening right here in Houston. Here are two innovative projects in the works at local institutions.

UH researcher designs app to monitor best times to shop

A UH professor is putting safe shopping at your fingertips. Photo via UH.edu

When is the best time to run an errand in the pandemic era we currently reside? There might be an app for that. Albert Cheng, professor of computer science and electrical and computer engineering at the University of Houston, is working on a real-time COVID-19 infection risk assessment and mitigation system. He presented his plans at the Institute of Electrical and Electronics Engineers conference HPC for Urgent Decision Making and will publish the work in IEEE Xplore.

Cheng's work analyzes up-to-date data from multiple open sources to see when is the best time to avoid crowds and accomplish activities outside the home.

"Preliminary work has been performed to determine the usability of a number of COVID-19 data websites and other websites such as grocery stores and restaurants' popular times and traffic," Cheng says in a UH release. "Other data, such as vaccination rates and cultural factors (for example, the percentage of people willing to wear facial coverings or masks in an area), are also used to determine the best grocery store to shop in within a time frame."

To use the app, a user would input their intended destinations and the farthest distance willing to go, as well as the time frame of the trip. The risk assessment and mitigation system, or RT-CIRAM, then "provides as output the target location and the time interval to reach there that would reduce the chance of infections," said Cheng.

There's a lot to it, says Cheng, and the process is highly reliant on technology.

"We are leveraging urgent high-performance cloud computing, coupled with time-critical scheduling and routing techniques, along with our expertise in real-time embedded systems and cyber-physical systems, machine learning, medical devices, real-time knowledge/rule-based decision systems, formal verification, functional reactive systems, virtualization and intrusion detection," says Cheng.

2 Houston hospitals team up with immunotherapy company for new vaccine for Africa

The new vaccine will hopefully help mitigate spread of the disease in Sub-Saharan Africa. Photo via bcm.edu

Baylor College of Medicine and Texas Children's Hospital have teamed up with ImmunityBio Inc. — a clinical-stage immunotherapy company — under a licensing agreement to develop a safe, effective and affordable COVID-19 vaccine.

BCM has licensed out a recombinant protein COVID-19 vaccine candidate that was developed at the Texas Children's Hospital Center for Vaccine Development to ImmunityBio. According to the release, the company engaged in license negotiations with the BCM Ventures team, about the vaccine that could address the current pandemic needs in South Africa.

"We hope that our COVID-19 vaccine for global health might become an important step towards advancing vaccine development capacity in South Africa, and ultimately for all of Sub-Saharan Africa," says Dr. Peter Hotez, professor and dean of the National School of Tropical Medicine at Baylor and co-director of the Texas Children's Hospital Center for Vaccine Development.

ImmunityBio, which was founded in 2014 by Dr. Patrick Soon-Shiong, is working on innovative immunotherapies that address serious unmet needs in infectious diseases, according to a news release from BCM.

"There is a great need for second-generation vaccines, which are accessible, durable and offer broad protection against the emerging variants," says Soon-Shiong. "ImmunityBio has executed on a heterologous ("mix-and-match") strategy to develop a universal COVID-19 vaccine. To accomplish this, we have embarked upon large-scale good manufacturing practices and development of DNA (adenovirus), RNA (self-amplifying mRNA) and subunit protein (yeast) vaccine platforms. This comprehensive approach will leverage our expertise in these platforms for both infectious disease and cancer therapies."

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