This week's roundup of Houston innovators includes Dorit Donoviel of TRISH, Anu Pansare of gBETA, and Christine Galib and Courtney Cogdill of The Ion. Courtesy photos

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to four innovators across industries recently making headlines — from space tech to startup development organizations.

Dorit Donoviel, director of the Translational Research Institute for Space Health

NASA has renewed its support for Baylor College of Medicine's Translational Research Institute for Space Health. Libby Neder Photography

Baylor College of Medicine's Translational Research Institute for Space Health, known as TRISH, got the green light on a grant renewal from NASA, which will allow the organization to continue to conduct biomedical research geared at protecting astronauts in deep space through 2028. NASA opted to continue the partnership and now TRISH will receive additional funding of up to $134.6 million from 2022 to 2028.

"NASA has received outstanding value from our bold approach to sourcing and advancing space health research and technologies," institute director Dorit Donoviel, says in a statement. "We are proud to be NASA's partner in its human space exploration mission and to be supporting the research necessary to create new frontiers in healthcare that will benefit all humans." Click here to read more.

Anu Pansare, director of gBETA Houston

Anu Pansare has joined the local gBETA team. Photo via gbetastartups.com

Anu Pansare has a new gig. The Sugar Land-based consultant has over 20 years of experience working with the likes of Chevron, Schlumberger, and Accenture, as well as smaller startups. Pansare, who's also been involved with the Houston Angel Network, recently started as director of gBETA's Houston office.

As the main liaison between Houston and gener8tor's national network, Pansare will lead gBETA's third cohort — for which applications are open online — through its free 7-week program, which is designed to help participating companies gain early customer traction and develop key metrics that will make them more marketable for future investment. Click here to read more.

Christine Galib and Courtney Cogdill of The Ion

Christine Galib and Courtney Cogdill of The Ion join the Houston Innovators Podcast to discuss the four accelerator programs that are striving to advance Houston. Photos courtesy of The Ion

Courtney Cogdill, program director of the Accelerator Hub, and Christine Galib, senior director, at The Ion joined the Houston Innovators Podcast to discuss what all they are focused on across the business accelerator programs at the hub. Now more than ever, innovators are dedicating their careers to resilient technologies that can enhance the city's future. And this effort comes naturally to Houstonians, Galib says on the podcast.

"There is an ethos here that is one of roll up your sleeves, collaborate, and get to work. Get the work done, and have fun while you're doing it," she says on the show. "We all come together in a time of challenge, and we really show each other that we're not just individually resilient, we are collectively resilient." Click here to read more and stream the episode.

Anu Pansare has joined the local gBETA team. Photo via gbetastartups.com

Early-stage accelerator names new Houston leader, opens applications for next cohort

now open

Houston's gBETA accelerator announced new leadership in conjunction with opening enrollment for its latest cohort this week.

The early-stage program, which is a part of Wisconsin-based gener8tor, has named Anu Pansare as its new director.

Pansare has spent the last 20 years at Sugar Land-based consulting firm Volyx and has also worked with big names like Chevron, Schlumberger, and Accenture, as well as smaller startups. She's also been involved with the Houston Angel Network. She will be replacing the accelerator's inaugural director Eléonore Cluzel in the position.

As the main liaison between Houston and gener8tor's national network, Pansare will lead gBETA's third cohort of early stage startups through its free 7-week program, which is designed to help participating companies gain early customer traction and develop key metrics that will make them more marketable for future investment.

"Downtown Launchpad is an inclusive ecosystem of tools, resources, and opportunities that help founders accelerate and scale their businesses to solve humankind's boldest challenges," says Robert Pieroni, director of economic development at Central Houston, in a press release. "The addition of Anu Pansare as gener8tor's new Houston director will strengthen our commitment to entrepreneurs in Houston and will help us evolve our strategy to better serve our founders, startups, partners, and our community."

Applications for the new cohort are open online until March 13.The zero-equity, no-fee program looks for locally based startups still in the early stage of business. Five companies will be selected.

The program is hosting a virtual webinar in partnership with SCORE Houston on March 1 to discuss the program and opportunities for interested startups. Event registration is free.

Houston's gBETA presence was launched thanks to a $1.25 million grant approved by the Downtown Redevelopment Authority in 2019 with support from Central Houston, the City of Houston, and Amegy Bank. The local team has an office at the Downtown Launchpad coworking space in the Amegy Bank Building on Main.

About a year into operations, gBETA has worked with 10 local startups in two cohorts across industries — from food tourism to sports technology, artificial intelligence for home buying to skincare and prescription solutions.

Pansare will be

holding virtual office hours for local entrepreneurs to provide insight and information about gBETA's Houston Spring 2021 program. More information on the program can be found at gBETA Houston's website or email Pansare directly at anu@gener8tor.com.
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Pharma giant considers Houston for $1B manufacturing campus

in the works

Another pharmaceutical giant is considering Houston’s Generation Park for a manufacturing hub.

According to a recent filing with the Texas Jobs, Energy, Technology and Innovation (JETI) program, Bristol Myers Squibb Co. is considering the northeast Houston management district for a new $1 billion multi-modal pharmaceutical manufacturing campus.

If approved, the campus, known as Project Argonaut, could create 489 jobs in Texas by 2031. Jobs would include operations technicians, engineering roles, administrative and management roles, production specialists, maintenance support, and quality control/assurance. The company predicts annual average wages for these positions to be around $96,000, according to the filing.

The project currently includes the 600,000-square-foot facility, but according to the filing, Bristol Myers Squibb “envisions this site growing in scale and capability well beyond its opening configuration."

The Texas JETI program offers companies temporary school property tax limitations in exchange for major capital investment and job creation. E.R. Squibb & Sons LLC applied for a 10-year tax abatement agreement in the Sheldon Independent School District.

The agreement promises a $ 1 billion investment. Construction would begin in 2027 and wrap in 2029.

“The proposed project reflects [Bristol Myers Squibb Co.’s] enduring commitment to bringing innovative medicines to patients and ensuring the long-term supply reliability they depend on,” the filing says. “The proposed project is purpose-built to support and manufacture medicines spanning multiple therapeutic areas and modalities, positioning the site as a long-term launch and commercial campus for decades to come. These medicines will provide therapies to the [Bristol Myers Squibb Co.’s] patients located in markets both nationally and internationally.”

The Fortune 100 company is considering 16 other cities for the new manufacturing facility in the Central and Eastern markets in the U.S. According to the Houston Chronicle, Bristol Myers Squibb Co is still in the “evaluation process” for its potential manufacturing site.

Last fall, Eli Lilly and Co. selected Generation Park for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

Houston health tech co. lands NIH grant for AI cancer prediction tool

fresh funding

Houston-based CellChorus and Stanford Medicine were recently awarded a Phase I Small Business Innovation Research grant for the company's AI platform to test how certain cancer patients will respond to therapies.

The funding comes from the National Cancer Institute of the National Institutes of Health. According to a filing, the grant totaled just under $400,000.

CellChorus, which spun out from the University of Houston’s Technology Bridge, has developed TIMING (Time-lapse Imaging Microscopy In Nanowell Grids), which analyzes the behavior of thousands of individual immune cells over time and can identify early indicators of treatment success or failure.

The company will work with Stanford's Dr. David Miklos and Dr. Saurabh Dahiya, who have built the Bone Marrow Transplantation and Cell Therapy Biobank. The biobank manages and stores biological samples from patients treated at their clinic and in clinical trials.

"Predicting which patients will achieve durable responses after CAR-T therapy remains one of the most important challenges in the field,” Miklos said in a news release. “We aim to uncover functional cellular signatures that can guide treatment decisions and improve patient outcomes.”

The project will specifically profile cells from patients with relapsed/refractory large B-cell lymphoma (r/rLBCL). According to CellChorus, only about half of r/rLBCL patients who receive CAR-T therapy "achieve a durable, long-term remission." Others do not respond to therapy or experience relapse.

“The sooner we know whether a cancer therapy is working, the better. To maximize patient benefit, we need technology that can provide a robust and early prediction of response to therapy. The technology needs to be scalable, cost-efficient, and capable of rapid turnaround times,” Rebecca Berdeaux, chief scientific officer of CellChorus, added in the release. “We are excited to work with Drs. David Miklos and Saurabh Dahiya and their colleagues on this very important project.”

CellChorus has previously received SBIR grants from federal agencies, including a $2.5 million award in 2024 from its National Center for Advancing Translational Sciences (NCATS) and a $2.3 million SBIR Fast-Track award from the National Institute of General Medical Sciences in 2023.

Houston museum showcases America's founding documents in rare exhibit

Experience History

As the United States prepares to celebrate its 250th birthday, Houstonians have a chance to see rare documents from the founding of the nation. Freedom Plane National Tour: Documents That Forged a Nation, presented by the National Archives Foundation, will be on display at the Houston Museum of Natural Science through Monday, May 25.

The collection includes a rare engraving of the original Declaration of Independence; official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton; a draft of the Bill of Rights; the Treaty of Paris, the documented that recognized America's independence from Great Britain; and the tally of votes approving the Constitution.

The National Archives specifically chose Houston as one of only eight cities in the country to host the exhibit as a means to help the documents reach a wider audience outside of the main hub of semiquincentennial events in New England and the Washington, D.C. area.

"One of the things we decided when we put the tour together because we wanted to be off the East Coast," said Patrick Madden, CEO of the National Archives Foundation, who was onsite for the exhibit's opening in Houston. "There's a lot of 250th celebration stuff happening in the original 13 colonies. How do we get it to major markets where larger numbers of people can see it? So in the case of Houston, obviously, [is a] major market in this part of the country, but also we've partnered with the museum twice before with National Archives exhibits, so we knew that they would be up to the task of handling the exhibit and the crowds."

The star of the collection is a rare engraving of the original Declaration of Independence. Secretary of State and future president John Quincy Adams commissioned 200 exact replicas of the document from engraver William J. Stone in 1823. Less than 50 now remain. Madden joyfully pointed out that there are errors in this document, a potent reminder that the men who forged a nation made mistakes.

"There's a couple of typos in it where they had to make corrections," said Madden. "So even the founders, you know, they're all human. That resonates because here these people are making this move against the most powerful nation in the world and putting their lives on the line for a country based on ideas."

Other impressive parts of the collection include official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton, as well as one of the drafts of the Bill of Rights. Many states would not ratify the Constitution until certain rights were included in the document, leading to Washington going on a national tour assuring state leaders enshrining protections was first on the list. The draft copy on display specifically shows the First Amendment in progress.

Houston is the fourth stop on the exhibition's tour, which will take the documents to Denver, Miami, Dearborn, and Seattle through the summer. Freedom Plane is just one part of a larger patriotic celebration at the HMNS, which includes a film series celebrating American science and culture and general Americana decoration throughout the main hall.

Admission to Freedom Plane is free to the public, but separate from general admission to the museum. Space is limited, and passes are available on a first-come, first-serve basis. Non-members should expect long waits or the possibility that the day's passes are sold out. Only museum members can reserve passes for specific times. Flash photography is prohibited due to the fragile nature of the documents.

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This article originally appeared on CultureMap.com.