A new partnership on Earth will help navigate the future of space health. Photo via NASA

Houston's Translational Research Institute for Space Health, or TRISH, has entered into an agreement with the Korea National Institute of Health to collaborate on research and discovery relating to space health.

According to a release, the organizations aim to uncover health findings that can assist in NASA's upcoming Artemis missions, as well as have Earth-bound impacts. The agreement is a Memorandum of Understanding which states that both organizations will "develop fruitful areas of cooperation for space health."

TRISH — which is affiliated with Baylor College of Medicine — and KNIH plan to collaborate on research related to mental health issues due to space travel, the challenges of food supply in deep space, the negative effects of space radiation and en-suite medical care for long-duration space travel.

“As in space, there should be no borders or boundaries to scientific discovery that benefits humankind,” Dorit Donoviel, associate professor in the Center for Space Medicine at Baylor and executive director TRISH said in a statement. “With this agreement, we will work together with the KNIH to collaborate and foster meaningful discussion with the ambition of keeping humans healthy in space and on Earth.”

TRISH announced last month that it will launch six experiments into space aboard Axiom Space's Ax-2 mission in consortium with CalTeach and MIT, which was originally targeted to launch this month.

TRISH is also slated to launch nine experiments on board SpaceX's Polaris Dawn mission, which is now expected to launch in September.

Some of the information found from these missions will become part of TRISH’s Enhancing eXploration Platforms and ANalog Definition, or EXPAND, program, which aims to boost human health on commercial space flights through its database. The program launched in 2021.
Houston-based TRISH's research will be done aboard the Polaris Dawn by its crew, which includes, from left to right, Mission Specialist and Medical Officer Anna Menon, Mission Pilot Scott “Kidd” Poteet, Mission Commander Jared “Rook” Isaacman, Mission Specialist Sarah Gillis. Photo courtesy Polaris Program/John Kraus

Houston space health institute to send experiments on upcoming SpaceX mission

ready for takeoff

The Translational Research Institute for Space Health at Baylor College of Medicine, or TRISH, announced this month that it will perform research experiments aboard SpaceX's upcoming Polaris Dawn mission that will look into everything from human vision to motion sickness to radiation levels while in space.

The research aboard Polaris Dawn will complement research supported by TRISH on the Inspiration4 all-civilian mission to orbit, which was also operated by SpaceX in 2021.

“The Institute’s mission is to help humans thrive in deep space,” Dr. Dorit Donoviel, TRISH executive director and associate professor for the Center for Space Medicine at Baylor, said in a statement. “We are grateful to our commercial space exploration partners, and in particular, the Polaris Program, who recognize how important it is to carry out and support health research in their missions, as a route to improving health for all humans in space and on Earth.”

Polaris Dawn is slated to launch from NASA’s Kennedy Space Center in Florida no earlier than March 2023. It is part of SpaceX's Polaris Program, which proposes three space missions. The first mission aims to reach the highest Earth orbit ever flown.

Four crew members will be onboard SpaceX’s Falcon 9 rocket for the Polaris Dawn mission. TRISH's experiments are part of 38 experiments from institutions that will be conducted on board at high-altitude Earth orbit.

The experiments are supported by federal funding from TRISH's cooperative agreement with NASA, as well as a donation from the Polaris Program.

According to a statement from TRISH, the experiments will include the following:

  • Collecting data related to the vision condition Spaceflight Associated Neuro-Ocular Syndrome (SANS), which is a top risk to human health in long-duration spaceflight
  • Quantifying alterations in body composition and fluid distribution during exposure to weightlessness
  • Directly measuring intracranial pressure changes to quantify the effects of weightlessness on the brain
  • Measuring cognitive performance, which reflects fitness for duty
  • Collecting biometric data to track physiologic changes, which could inform on changes in overall health
  • Using miniaturized, intelligent ultrasound to train the astronauts to scan themselves and deliver medical quality images
  • Testing ways to predict space motion sickness to improve crew safety and in-mission performance
  • Collecting data on the radiation environment to observe how space radiation may affect human systems
  • Providing biological samples for multi-omics analyses and storage in a long-term biobank to be available to researchers in the future

TRISH launched the first-ever commercial spaceflight medical research program in 2021, known as the Expand—Enhancing Exploration Platforms and Analog Definition—Program. Future findings from the Polaris Dawn mission will be added to the database, which compiles in-flight health data from multiple spaceflights.

TRISH was founded in 2016 with the mission of addressing the most pressing health risks and challenges associated with human deep space exploration.

TRISH is seeking space health scientists to support with new initiative. Photo via BCM.edu

Houston organization launches new fellowship to support the future of space health

we have liftoff

A space health-focused organization has announced a new fellowship opportunity for scientists.

The Translational Research Institute for Space Health, or TRISH, housed out of Baylor College of Medicine has announced — along with partners California Institute of Technology and Massachusetts Institute of Technology — a new fellowship opportunity for postdoctoral scientists tackling the health challenges of deep space exploration and innovating solutions.

“TRISH is a launch pad for exceptional postdoctoral fellows investigating new ways to protect human health,” says Rachael Dempsey, education officer for TRISH, in a news release. “Space health science leads to innovations that help humans thrive, wherever they explore. Our institute is committed to building a diverse and engaged workforce prepared for humanity’s future in space.”

TRISH’s postdoctoral fellowship program will select fellows who will then participate in TRISH’s Academy of Bioastronautics — a mentorship community for space health professionals. The professionals will receive a two-year salary stipend as they conduct their work.

“America’s future is in space exploration, and it’s time to invest in the scientists that will bring forward ground-breaking advances to enable that exciting future,” says Dr. Dorit Donoviel, TRISH executive director, in the release.

Those interested can submit their proposals together with an identified mentor and institution online up until January 26, 2023. Independent investigators with existing research grant support may request to be listed as possible mentors for this program by contacting Jean De La Croix Ndong at jndong@nasaprs.com, per the news release.

Supported in part by NASA, Houston-based TRISH is focused on supporting scientists committed to creating space health treatments and solution for the future of space travel.

The human body undergoes specific challenges in space. A new film from TRISH explains the unique phenomenon and how research is helping to improve human life in space. Photo courtesy of NASA

Houston-based organization premieres space health tech documentary

watch now

A Houston space health organization has launched a film that is available to anyone interested in how space affects the human body.

The Translational Research Institute for Space Health, or TRISH, which is housed out of Baylor College of Medicine in consortium with Caltech and the Massachusetts Institute of Technology, announced a new documentary — “Space Health: Surviving in the Final Frontier.” The film, which covers how space affects humans both physically and mentally. It's free to watch online.

“This documentary provides an unprecedented look into the challenges – physical and mental – facing space explorers and the types of innovative research that TRISH supports to address these challenges,” says Dr. Dorit Donoviel, TRISH executive director and associate professor in Baylor’s Center for Space Medicine, in a news release. “We hope the film inspires students and researchers alike to see how their work could one day soon improve the lives of human explorers.”

The documentary interviews a wide range of experts — scientists, flight surgeons, astronauts, etc. — about all topics related to health, like food, medicine, radiation, isolation, and more. Some names you'll see on the screen include:

  • Former NASA astronaut Nicole Stott
  • Active NASA astronaut Victor Glover
  • NASA Associate Administrator Kathy Lueders
  • Inspiration4 Commander Jared Issacman
  • TRISH-funded researchers Level Ex CEO Sam Glassenberg and Holobiome CEO Philip Strandwitz

“Understanding and solving the challenges that face humans in space is critical work,” says Dr. Jennifer Fogarty, TRISH chief scientific officer, in the release. “Not only does space health research aim to unlock new realms of possibility for human space exploration, but it also furthers our ability to innovate on earth, providing insights for healthcare at home.”

TRISH is funded by NASA’s Human Research Program and seeks both early stage and translation-ready research and technology to protect and improve the health and performance of space explorers. This film was enabled by a collaboration with NASA and HRP.

This week's roundup of Houston innovators includes Dorit Donoviel of TRISH, Nuri Firat Ince of UH, and Vanessa Wade of Connect the Dots. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from space to engineering — recently making headlines in Houston innovation.


Dorit Donoviel, director of the Translational Research Institute for Space Health

Dorit Donoviel, director of the Translational Research Institute for Space Health

The new program will work with commercial spaceflight crews to bring back crucial research to one database. Photo via Libby Neder Photography

The Translational Research Institute for Space Health, or TRISH, at Baylor College of Medicine announced a unique program that will work with commercial spaceflight providers and their passengers. The EXPAND — Enhancing eXploration Platforms and Analog Definition — Program will collect information and data from multiple space flights and organize it in one place. TRISH selected TrialX to build the centralized database.

"The space environment causes rapid body changes. This can help us understand how we humans react to and overcome stress. Ensuring that space explorers remain healthy pushes us to invent new approaches for early detection and prevention of medical conditions," says Dorit Donoviel, executive director at TRISH, in the release.

"Studying a broad range of people in space increases our knowledge of human biology. TRISH's EXPAND program will leverage opportunities with commercial spaceflight providers and their willing crew to open up new research horizons." Click here to read more.

Nuri Firat Ince, associate professor of biomedical engineering at UH

A medical device designed by a UH professor will close the loop with high frequency brain waves to prevent seizures from occurring. Photo via uh.edu

Nuri Firat Ince, an associate professor of biomedical engineering at UH, has received a federal grant aimed at helping stop epileptic seizures before they start. The BRAIN Initiative at the National Institute of Neurological Disorders and Stroke awarded the $3.7 million grant to go toward Ince's work to create a seizure-halting device based on his research.

According to UH, Ince has reduced by weeks the time it takes to locate the seizure onset zone (SOZ), the part of the brain that causes seizures in patients with epilepsy. He's done this by detecting high-frequency oscillations (HFO) forming "repetitive waveform patterns" that identify their location in the SOZ.

"If the outcomes of our research in acute settings become successful, we will execute a clinical trial and run our methods with the implanted … system in a chronic ambulatory setting," Ince says. Click here to read more.

Vanessa Wade, founder and owner of Connect the Dots

It's time for large corporations to step up to support small businesses founded by people of color. Photo courtesy

In her guest column for InnovationMap, Vanessa Wade addressed some of the challenges she faced founding a company as a person of color — specifically the lack of access to funding. In the article, she calls corporations to action to help business leaders like herself.

"The journey ahead can feel discouraging, but the good news is that now I have a much better idea of what it will take to build an equitable road back and get businesses like mine on even footing," she writes. Click here to read more.

The new program will work with commercial spaceflight crews to bring back crucial research to one database. Photo via NASA/Unsplash

Houston organization launches the first commercial spaceflight medical research program

out of this world health care

With commercial space activity reaching cruising altitude, a Houston space health research organization has introduced a new program to create a centralized database.

The Translational Research Institute for Space Health, or TRISH, at Baylor College of Medicine announced a unique program that will work with commercial spaceflight providers and their passengers. The EXPAND — Enhancing eXploration Platforms and Analog Definition — Program will collect information and data from multiple space flights and organize it in one place. TRISH selected TrialX to build the centralized database.

As a partner to the NASA Human Research Program, the Houston-based organization's mission is to reduce health risks for astronauts and uncover advances for terrestrial healthcare, according to a news release.

"The space environment causes rapid body changes. This can help us understand how we humans react to and overcome stress. Ensuring that space explorers remain healthy pushes us to invent new approaches for early detection and prevention of medical conditions," says Dorit Donoviel, executive director at TRISH, in the release. "Studying a broad range of people in space increases our knowledge of human biology. TRISH's EXPAND program will leverage opportunities with commercial spaceflight providers and their willing crew to open up new research horizons."

The new collaborative program is meant to address the challenges that humans face on space missions — early detection and treatment of medical conditions, protection from radiation, mental health, team dynamics, and more. TRISH has been working on these challenges since its inception.

"This ground-breaking research model is only possible because everyone — scientists, commercial spaceflight companies, and passengers - recognizes the importance of space health research, and what we can learn by working together," says Dr. Emmanuel Urquieta, TRISH's chief medical officer, in the release.

EXPAND's first collaboration is the Inspiration4 mission, which is launching on September 15. The all-civilian crew will perform a variety of TRISH-supported human health experiments during their time in orbit.

"Shorter commercial space flights like Inspiration4 have similarities to early NASA Artemis missions," says Jimmy Wu, TRISH's senior biomedical engineer. "This allows TRISH an opportunity to test new health and performance technologies for future NASA astronauts."

The potential impact of innovation with this new centralized database and biobank is profound, says James Hury, TRISH's deputy director and chief innovation officer.

"The EXPAND database has the flexibility to seamlessly take in multiple types of data from different flight providers in order to create a repository that can integrate information," says Hury in the release. "A centralized, standardized research database and biobank will increase access to knowledge about human health for the global research community."

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Houston-based equitable entrepreneurship tech platform expands programs

coming soon

Fresh off of celebrating the dismissal of a lawsuit from former Trump Administration officials, Hello Alice is expanding some of its offerings for entrepreneurs.

In partnership with top organizations — like Progressive, Antares Capital, Wells Fargo, and FedEx — Hello Alice has added new offerings for its 2024 Boost Camp programs, a mix of skill-building support and grant opportunities.

“We are fortunate to continue working with great enterprise partners who share our commitment to supporting Main Street through crucial grants and mentorship programs,” Carolyn Rodz, CEO and co-founder of Hello Alice, says in a news release. “Small businesses drive our economy, yet often lack the necessary financing and resources. By partnering with major companies, Hello Alice is ensuring that small businesses have access to the tools and opportunities they need to thrive and create jobs in their local communities. Together, we are building a robust support system that fosters innovation and growth for small businesses across the country.”

This year's programs, according to Hello Alice, are as follows:

  • Antares Capital REACH Cohort: The Antares REACH Grant Program provides $20,000 grants to small businesses. Grant recipients will also take part in Antares’ Growth Track Boost Camp program, a digital community which will be home to monthly business coaching workshops, mentorship, networking, and more. Applications are open until June 28, and the program begins August 8.
  • Progressive Driving Small Business Forward Grant & Booster Camp Program: Progressive is dedicating $1 million to award 20 deserving businesses with a $50,000 grant each. Grant recipients will be invited to attend an exclusive 12-week virtual Boost Camp coaching program. Applications have closed for the program beginning September 10.
  • Wells Fargo: Wells Fargo is supporting four virtual accelerator programs over the next 18 months, designed to support up to 500 participants for each program, with a focus on business health and credit-building practices. Applications will be announced this summer for the program, which will begin in early fall.
  • FedEx: The FedEx Entrepreneur Fund supports entrepreneurs in the United States by providing them with the necessary funding, resources, and networks to enhance the success of their businesses, including the Boost Camp coaching program.
  • Applications will be announced this fall for the program, which will begin in the winter.

More information and application access is available online.

Last year's Boost programs benefitted 100 small businesses, according to Hello Alice, which reported that the 2023 Antares REACH Cohort resulted in 60 percent of participants seeing an increase in their Business Health Score and 93 percent felt better equipped to confront challenges and capitalize on opportunities. In the end, 85 percent of participants feeling more optimistic about their business growth prospects.

"Hello Alice is proud to partner with high-level enterprise companies to empower small businesses and foster their success," Natalie Diamond, vice president of business development at Hello Alice, adds. "Together, we are creating unparalleled opportunities for entrepreneurs to achieve brand success, drive financial fitness, and thrive in today's competitive market. Our joint endeavors not only offer access to capital and resources but also provide tailored guidance and mentorship, arming small business owners with the insights and support necessary to navigate challenges and seize growth opportunities.”

Houston company's sustainable oil product reaches milestone production capacity 5 years early

overachieving

Houston-based biotech company Cemvita has achieved a key production goal five years ahead of schedule.

Thanks to technology advancements, Cemvita is now capable of generating 500 barrels per day of sustainable oil from carbon waste at its first commercial plant. As a result, Cemvita has quadrupled output at the Houston plant. The company had planned to reach this milestone in 2029.

Cemvita, founded in 2017, says this achievement paves the way for increased production capacity, improved operational efficiency, and an elevated advantage in the sustainable oil market.

“What’s so amazing about synthetic biology is that humans are just scratching the surface of what’s possible,” says Moji Karimi, co-founder and CEO of Cemvita. “Our focus on the first principles has allowed us to design and create new biotech more cheaply and faster than ever before.”

The production achievement follows Cemvita’s recent breakthrough in development of a solvent-free extraction bioprocess.

In 2023, United Airlines agreed to buy up to one billion gallons of sustainable aviation fuel from Cemvita’s first full-scale plant over the course of 20 years.

Cemvita’s investors include the UAV Sustainable Flight Fund, an investment arm of Chicago-based United; Oxy Low Carbon Ventures, an investment arm of Houston-based energy company Occidental Petroleum; and Japanese equipment and machinery manufacturer Mitsubishi Heavy Industries.

Tech disruptions sparked by Texas co.'s update highlight the fragility of globally connected technology

Airlines, banks, hospitals and other risk-averse organizations around the world chose cybersecurity company CrowdStrike to protect their computer systems from hackers and data breaches.

But all it took was one faulty CrowdStrike software update to cause global disruptions Friday that grounded flights, knocked banks and media outlets offline, and disrupted hospitals, retailers and other services.

“This is a function of the very homogenous technology that goes into the backbone of all of our IT infrastructure,” said Gregory Falco, an assistant professor of engineering at Cornell University. “What really causes this mess is that we rely on very few companies, and everybody uses the same folks, so everyone goes down at the same time.”

The trouble with the update issued by CrowdStrike and affecting computers running Microsoft's Windows operating system was not a hacking incident or cyberattack, according to CrowdStrike, which apologized and said a fix was on the way.

But it wasn't an easy fix. It required “boots on the ground” to remediate, said Gartner analyst Eric Grenier.

“The fix is working, it’s just a very manual process and there’s no magic key to unlock it,” Grenier said. “I think that is probably what companies are struggling with the most here.”

While not everyone is a client of CrowdStrike and its platform known as Falcon, it is one of the leading cybersecurity providers, particularly in transportation, healthcare, banking and other sectors that have a lot at stake in keeping their computer systems working.

“They’re usually risk-averse organizations that don’t want something that’s crazy innovative, but that can work and also cover their butts when something goes wrong. That’s what CrowdStrike is,” Falco said. “And they’re looking around at their colleagues in other sectors and saying, ‘Oh, you know, this company also uses that, so I’m gonna need them, too.’”

Worrying about the fragility of a globally connected technology ecosystem is nothing new. It's what drove fears in the 1990s of a technical glitch that could cause chaos at the turn of the millennium.

“This is basically what we were all worried about with Y2K, except it’s actually happened this time,” wrote Australian cybersecurity consultant Troy Hunt on the social platform X.

Across the world Friday, affected computers were showing the “blue screen of death” — a sign that something went wrong with Microsoft's Windows operating system.

But what's different now is “that these companies are even more entrenched,” Falco said. "We like to think that we have a lot of players available. But at the end of the day, the biggest companies use all the same stuff.”

Founded in 2011 and publicly traded since 2019, CrowdStrike describes itself in its annual report to financial regulators as having “reinvented cybersecurity for the cloud era and transformed the way cybersecurity is delivered and experienced by customers.” It emphasizes its use of artificial intelligence in helping to keep pace with adversaries. It reported having 29,000 subscribing customers at the start of the year.

The Austin, Texas-based firm is one of the more visible cybersecurity companies in the world and spends heavily on marketing, including Super Bowl ads. At cybersecurity conferences, it's known for large booths displaying massive action-figure statues representing different state-sponsored hacking groups that CrowdStrike technology promises to defend against.

CrowdStrike CEO George Kurtz is among the most highly compensated in the world, recording more than $230 million in total compensation in the last three years. Kurtz is also a driver for a CrowdStrike-sponsored car racing team.

After his initial statement about the problem was criticized for lack of contrition, Kurtz apologized in a later social media post Friday and on NBC's “Today Show.”

“We understand the gravity of the situation and are deeply sorry for the inconvenience and disruption,” he said on X.

Richard Stiennon, a cybersecurity industry analyst, said this was a historic mistake by CrowdStrike.

“This is easily the worst faux pas, technical faux pas or glitch of any security software provider ever,” said Stiennon, who has tracked the cybersecurity industry for 24 years.

While the problem is an easy technical fix, he said, it’s impact could be long-lasting for some organizations because of the hands-on work needed to fix each affected computer. “It’s really, really difficult to touch millions of machines. And people are on vacation right now, so, you know, the CEO will be coming back from his trip to the Bahamas in a couple of weeks and he won’t be able to use his computers.”

Stiennon said he did not think the outage revealed a bigger problem with the cybersecurity industry or CrowdStrike as a company.

“The markets are going to forgive them, the customers are going to forgive them, and this will blow over,” he said.

Forrester analyst Allie Mellen credited CrowdStrike for clearly telling customers what they need to do to fix the problem. But to restore trust, she said there will need to be a deeper look at what occurred and what changes can be made to prevent it from happening again.

“A lot of this is likely to come down to the testing and software development process and the work that they’ve put into testing these kinds of updates before deployment,” Mellen said. “But until we see the complete retrospective, we won’t know for sure what the failure was.”