Houston space health research organization names 3 fellows for bioastronautics program

hello fellows

TRISH, or the Translational Institute of Space Health, has named three fellows to its new program. Photo via bcm.edu

Three Texas scientists have been selected for a Houston organization's prestigious program focused on space health.

TRISH, or the Translational Research Institute for Space Health, which is based out of Houston-based Baylor College of Medicine, has announced its selections for the TRISH 2023 fellowship. The program, announced last fall, is in partnership with California Institute of Technology and Massachusetts Institute of Technology.

“Supporting the next generation of space health researchers ensures that we will have the best possible data to make evidence-based decisions about managing human systems risk for exploration class missions,” says Dr. Jennifer Fogarty, TRISH’s chief scientific officer, in a news release. “By investing in TRISH postdoctoral fellows, we’re investing in future experts who will strive to solve the complex problems and risks associated with human space exploration. We are thrilled to welcome these accomplished early-career scientists to the TRISH community.”

The three selected postdoctoral fellows are focused on researching within space health — specifically reducing the health risks associated with spaceflight. They will receive a two-year salary stipend and participate in TRISH’s Academy of Bioastronautics, a mentorship community for space health professionals.

“Pursuing my postdoctoral training at TRISH has accelerated my career and expanded my research portfolio, enabling me to make new connections and become a more well-rounded scientist,” says Dr. Evan Buettmann, a TRISH third-year postdoctoral fellow at Virginia Commonwealth University, in the release. “Having completed my Ph.D. in bone regeneration, I didn’t initially anticipate that my studies would lead me to an academic career in space health. TRISH stood out to me as an excellent place to complete my postdoctoral training, as it’s at the cutting edge of both space science and medicine and offers extensive mentorship and leadership opportunities.”

This 2023 cohort of fellows include:

  • Stephanie Dudzinski, M.D., Ph.D. Her research focuses on extending healthy life in space by characterizing radiation-induced pro-inflammatory response and enhancing wound repair and recovery with radiation- mitigating thrombin peptide. Her mentor is Steven Frank, M.D., of the University of Texas MD Anderson Cancer Center.
  • Adrien Robin, Ph.D., who is looking at the effect of deconditioning on-gravitational dose-response curves for cardiovascular and ocular variables in men and women and is being mentored by Ana Diaz Artiles, Ph.D., Texas A&M Engineering Experiment Station.
  • Katherine Wozniak, Ph.D., who is defining gut microbial changes to space-like radiation to develop a radiation-resistant microbiome. Her mentor is Robert Britton, Ph.D., of Baylor College of Medicine.
In addition to supporting scientists through its fellowship program, TRISH is actively conducting research aboard commercial space flights — most recently with Axiom Space's Ax-2 mission..
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This week's roundup of Houston innovators includes Emmanuel Urquieta of TRISH, Ariel Jones of Qualtrics XM, and Lawson Gow of Pokatok. Photos courtesy

3 Houston innovators to know this week

WHO'S WHO

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from space health research to sports tech — recently making headlines in Houston innovation.


Dr. Emmanuel Urquieta, chief medical officer of TRISH

Emmanuel Urquieta, chief medical officer of TRISH, joins the Houston Innovators Podcast. Photo via LinkedIn

Since 2021, the Translational Research Institute for Space Health has conducted its research on four missions — which has meant an unparalleled access to space health data for TRISH.

“We really saw the value of implementing research in civilians because they are different from your traditional government astronaut,” Dr. Emmanuel Urquieta, chief medical officer for TRISH, says on the Houston Innovators Podcast. “In civilians, you see a more diverse population.”

Urquieta says TRISH's experiments on these missions all fall within a few pillars of space health, including space's effects on sensory motor skills, like balance and motion sickness, as well as mental health, environmental data from the vehicles, vital monitoring, and more. Read more.

Ariel Jones, head of health care provider solution strategy for Qualtrics XM

As the health care industry continues to evolve, experience management technology will play an increasingly important role in addressing health equity gaps and improving the health and well-being of patients across the globe. Photo courtesy

In a guest column for InnovationMap, Ariel Jones, head of health care provider solution strategy for Qualtrics XM, addresses inequalities in health care — and how technology, specifical experience management tech, can help bridge the gap.

"As the health care industry continues to evolve, experience management technology will play an increasingly important role in addressing health equity gaps and improving the health and well-being of patients across the globe," she writes. Read more.

Lawson Gow, co-founder of Pokatok

A new sports festival is headed to Houston next year. Photo courtesy of Pokatok

Pokatok, the recently announced, four-day sports festival is slated to take place April 4-7, 2024.

“Pokatok will not only be the largest gathering of the entire sports tech ecosystem, it will also be a true fan festival for sports enthusiasts,” says Gow in the news release. “Everyone speaks the language of sport, it’s an incredibly powerful unifier of our society, and this festival will bring together people from around the world to experience hundreds of events revolving around the new and the next in sport.”

The festival, which has secured support from Houston First, the Greater Houston Partnership, and the Harris County Houston Sports Authority to put on the event, will feature two tracks — one focused on sports innovation and the other surrounding a fan experience. Pokatok X will include an expo and showcase focused on sports innovation, bringing together startups, investors, accelerators, athletes, and industry experts to dive into sports tech. Read more.

Emmanuel Urquieta, chief medical officer of TRISH, joins the Houston Innovators Podcast. Photo via LinkedIn

Houston innovator on the importance of commercial missions for the future of space health research

HOUSTON INNOVATORS PODCAST EPISODE 189

With the rise of commercial space flight, researchers have increased access to space health data that's key to the future of the industry as a whole. The organization that's conducting this valuable research is based right in Houston's Texas Medical Center.

TRISH, or the Translational Research Institute for Space Health, is an organization based out of Baylor College of Medicine and partnered with NASA's Human Spaceflight group. As commercial space companies have emerged, TRISH has strategically aligned with these businesses to bring back health data from the civilian trips.

“Most of the research that’s done at NASA and other government agencies usually takes decades to get something that could be implemented in space or terrestrially," Dr. Emmanuel Urquieta, chief medical officer for TRISH, says on the Houston Innovators Podcast. "What we do at TRISH is something different.

"On the one hand, we look at really new technologies that are just an idea, but could be really game changing," he continues. "Then on the other hand, we look at technologies already in the market that could be tweaked to work in spaceflight.”

Since 2021, TRISH has conducted its research on four missions — Inspiration4, the first all-civilian mission to space; Axiom Mission 1, the first all civilian mission to the International Space Station; MS20, which flew two Japanese civilians to ISS; and, most recently, Axiom Mission 2, which included the first all-private crew commanded by a woman and two members of the Kingdom of Saudi Arabia's national astronaut program.

“We really saw the value of implementing research in civilians because they are different from your traditional government astronaut,” Urquieta says. “In civilians, you see a more diverse population.”

Urquieta says TRISH's experiments on these missions all fall within a few pillars of space health, including space's effects on sensory motor skills, like balance and motion sickness, as well as mental health, environmental data from the vehicles, vital monitoring, and more.

“We’ve developed a capability to collect high-priority, high-value data from these space flight participants without having to train them for long periods of time — which is a challenge, because they don’t train for years like traditional astronauts,” he explains.

The plan, Urquieta says, is to be able to share TRISH's space health data in order to more safely send humans into space. He shares more about TRISH's program and the challenges the organization faces on the show. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

A new partnership on Earth will help navigate the future of space health. Photo via NASA

Houston space research nonprofit announces new international agreement

partnership launch

Houston's Translational Research Institute for Space Health, or TRISH, has entered into an agreement with the Korea National Institute of Health to collaborate on research and discovery relating to space health.

According to a release, the organizations aim to uncover health findings that can assist in NASA's upcoming Artemis missions, as well as have Earth-bound impacts. The agreement is a Memorandum of Understanding which states that both organizations will "develop fruitful areas of cooperation for space health."

TRISH — which is affiliated with Baylor College of Medicine — and KNIH plan to collaborate on research related to mental health issues due to space travel, the challenges of food supply in deep space, the negative effects of space radiation and en-suite medical care for long-duration space travel.

“As in space, there should be no borders or boundaries to scientific discovery that benefits humankind,” Dorit Donoviel, associate professor in the Center for Space Medicine at Baylor and executive director TRISH said in a statement. “With this agreement, we will work together with the KNIH to collaborate and foster meaningful discussion with the ambition of keeping humans healthy in space and on Earth.”

TRISH announced last month that it will launch six experiments into space aboard Axiom Space's Ax-2 mission in consortium with CalTeach and MIT, which was originally targeted to launch this month.

TRISH is also slated to launch nine experiments on board SpaceX's Polaris Dawn mission, which is now expected to launch in September.

Some of the information found from these missions will become part of TRISH’s Enhancing eXploration Platforms and ANalog Definition, or EXPAND, program, which aims to boost human health on commercial space flights through its database. The program launched in 2021.
Here's what experiments TRISH is launching aboard Axiom Space's next mission. Photo via NASA

Houston space health institute to launch more experiments into space on upcoming mission

ready for takeoff

Houston's Translational Research Institute for Space Health, or TRISH, will launch six more experiments into space this spring aboard Axiom Space's Ax-2 mission, the organization announced this week.

The biomedical research conducted through TRISH, in consortium with CalTeach and MIT, will look into how space travel impacts everything from motion sickness to memory over the course of the mission's 10-day stint on the International Space Station.

The crew will consist of four astronauts: Commander Peggy Whitson (previously with NASA), Pilot John Shoffner and Mission Specialists Ali AlQarni and Rayyanah Barnawi. It's a historic team, bringing the first female private space crew commander and the first Saudi astronauts to the ISS.

“Insights gathered from this work improve our understanding of how the human body and mind respond to spaceflight, helping us to prepare future astronauts to remain safe and healthy during longer-duration missions," Dr. Dorit Donoviel, TRISH executive director and professor in the Center for Space Medicine at Baylor College of Medicine, says in a statement.

The six projects onboard the mission have been developed by researchers within TRISH as well as the University of Pennsylvania Perelman School of Medicine, Johns Hopkins University and Baylor College of Medicine. They aim to assess the following:

  • Spaceflight participants’ performance in memory, abstraction, spatial orientation, emotion recognition, risk decision making and sustained attention before and after the mission -Astronauts’ inner ears and eyes' response to motion before and after space travel and how this relates to motion sickness and nausea during launch and landing
  • The effects of spaceflight on the human body at the genomic level
  • Changes to the eyes and brain during spaceflight
  • Astronaut's sleep, personality, health history, team dynamics and immune-related symptoms
  • Sensorimotor abilities and changes in space and how this can impact astronauts' ability to stand, balance and have full body control on the moon

Some of this information will become part of TRISH’s Enhancing eXploration Platforms and ANalog Definition, or EXPAND, program, which aims to boost human health on commercial space flights through its database. The program launched in 2021.

Ax-2 is Axiom's second all-private astronaut mission to the ISS and will launch out of NASA’s Kennedy Space Center in Florida aboard a SpaceX's Dragon spacecraft. Axiom was first established in 2016 with the goal of building the world's first commercial space station.

TRISH is also slated to launch nine experiments on board SpaceX's Polaris Dawn mission, which is now expected to launch this summer. The research aboard Polaris Dawn is intended to complement research supported by TRISH on the Inspiration4 all-civilian mission to orbit, which was also operated by SpaceX in 2021.

Houston-based TRISH's research will be done aboard the Polaris Dawn by its crew, which includes, from left to right, Mission Specialist and Medical Officer Anna Menon, Mission Pilot Scott “Kidd” Poteet, Mission Commander Jared “Rook” Isaacman, Mission Specialist Sarah Gillis. Photo courtesy Polaris Program/John Kraus

Houston space health institute to send experiments on upcoming SpaceX mission

ready for takeoff

The Translational Research Institute for Space Health at Baylor College of Medicine, or TRISH, announced this month that it will perform research experiments aboard SpaceX's upcoming Polaris Dawn mission that will look into everything from human vision to motion sickness to radiation levels while in space.

The research aboard Polaris Dawn will complement research supported by TRISH on the Inspiration4 all-civilian mission to orbit, which was also operated by SpaceX in 2021.

“The Institute’s mission is to help humans thrive in deep space,” Dr. Dorit Donoviel, TRISH executive director and associate professor for the Center for Space Medicine at Baylor, said in a statement. “We are grateful to our commercial space exploration partners, and in particular, the Polaris Program, who recognize how important it is to carry out and support health research in their missions, as a route to improving health for all humans in space and on Earth.”

Polaris Dawn is slated to launch from NASA’s Kennedy Space Center in Florida no earlier than March 2023. It is part of SpaceX's Polaris Program, which proposes three space missions. The first mission aims to reach the highest Earth orbit ever flown.

Four crew members will be onboard SpaceX’s Falcon 9 rocket for the Polaris Dawn mission. TRISH's experiments are part of 38 experiments from institutions that will be conducted on board at high-altitude Earth orbit.

The experiments are supported by federal funding from TRISH's cooperative agreement with NASA, as well as a donation from the Polaris Program.

According to a statement from TRISH, the experiments will include the following:

  • Collecting data related to the vision condition Spaceflight Associated Neuro-Ocular Syndrome (SANS), which is a top risk to human health in long-duration spaceflight
  • Quantifying alterations in body composition and fluid distribution during exposure to weightlessness
  • Directly measuring intracranial pressure changes to quantify the effects of weightlessness on the brain
  • Measuring cognitive performance, which reflects fitness for duty
  • Collecting biometric data to track physiologic changes, which could inform on changes in overall health
  • Using miniaturized, intelligent ultrasound to train the astronauts to scan themselves and deliver medical quality images
  • Testing ways to predict space motion sickness to improve crew safety and in-mission performance
  • Collecting data on the radiation environment to observe how space radiation may affect human systems
  • Providing biological samples for multi-omics analyses and storage in a long-term biobank to be available to researchers in the future

TRISH launched the first-ever commercial spaceflight medical research program in 2021, known as the Expand—Enhancing Exploration Platforms and Analog Definition—Program. Future findings from the Polaris Dawn mission will be added to the database, which compiles in-flight health data from multiple spaceflights.

TRISH was founded in 2016 with the mission of addressing the most pressing health risks and challenges associated with human deep space exploration.

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Extended reality will have a big impact on business, this Houston expert says

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What does your reality look like? Look around you. What do you see? It would be safe to say (almost guarantee) that you are looking at a screen right now, correct? We are consumers of information and use screens to access, view, and create information.

But why are we spending so much of our time looking at screens?

One poll stated that the average adult will spend 34 years of their lives looking at screens. It almost feels that screens (TV, laptop, or phone) have become so ubiquitous in everyday life that they have blended into our reality and are just ‘there’. Do you think the inventor of the TV, John Logie Baird, ever fully grasped how much the fabric of society would revolve around his invention? Time and time again, incredible disruptions have always come from breaking the ‘norm’ and given the vast level of integration of screens into our everyday reality, this ‘norm’ feels long overdue for innovation. This is where the world of augmented reality and spatial computing comes into play.

The COVID-19 pandemic saw an unprecedented shift to even more screen time and interactions using remote video communication platforms. It was also around this time that wireless virtual reality headsets were, for the first time ever, economically accessible to the consumer due to the large push of one multinational corporation. Fast forward to 2023, there are even more companies beginning to enter the market with new extended reality (XR) headsets (i.e. virtual, mixed, and augmented reality) that offer spatial computing – the ability for computers to blend into the physical worlds (amongst other things).

Some of our innovation engineering activities at the Houston Methodist Institute for Technology, Innovation, and Education (MITIE) have focused on specific use cases of XR in surgical education and training. One of our projects, the MITIEverse, is a VR-based platform focused on creating the first-ever metaverse for medical innovation. It is a fully immersive VR environment that allows the user to view 3D-rendered patient anatomies whilst watching the actual patient procedure, even offering the ability to meet the surgeon who performed the operation. It also affords the ability to give a ‘Grand Rounds’ style presentation to an audience of 50 participants.

We have looked at using augmented reality to control robotic-assisted surgery platforms. In our proof-of-concept prototype, we successfully demonstrated the manipulation of guide wires and catheters using nothing more than an augmented reality headset, illustrating the possibility of surgeons performing surgery at a distance. Houston Methodist is dedicated to transforming healthcare using the latest innovative technology including XR. The question we now need to ask – is society ready and willing to replace screens with XR headsets?

To learn more about our XR initiatives and other Houston’s cross-industry innovation collaborations, attend Pumps & Pipes Annual Event 2023, Problem Xchange: Where Solutions Converge next month at The Ion.

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Stuart Corr is the director of Innovation Systems Engineering at Houston Methodist and executive director of Pumps & Pipes.

Houston surprisingly plummets in prestigious list of best cities in the world

htown down

Economic investments and population growth are definitive highlights of Houston's success over the last year, but they weren't enough to keep it within the top 50 best cities in the world, according to a prestigious report by Canada-based real estate and tourism marketing advisors Resonance Consultancy.

The annual "World's Best Cities" report quantifies the relative qualities of place, reputation, and competitive identity for the world's principal cities with metropolitan populations of 1 million or more.

London topped the list again for 2024, followed by Paris (No. 2), New York (No. 3), Tokyo (No. 4), and Singapore (No. 5).

Houston slipped from its position as No. 42 last year to a surprising No. 66 in 2024.

However, the report primarily focuses on the city, its cultural diversity, and its astronomical prospects, rather than its ranking.

"In the past year, immigration both domestic and international has swelled the metro population to above seven million and the city today is one of America’s most ethnically diverse metropolises," the report said.

Houston's cultural footprint has always been significant, and has substantially developed throughout the years. According to the report (which cited the latest U.S. Census data), there are over 145 languages being spoken "at home" which is nearly as many as New York. And the city will soon have a new community center for those of all faiths and backgrounds: the nation's first Ismaili Center.

But it's Houston's stellar ambitions as Space City that is a major highlight in its shining overview.

"[The] Houston Spaceport is an FAA-licensed urban commercial spaceport offering unprecedented access to a thriving aerospace community," the report said. "The head start the city has in building a cluster of aerospace companies manufacturing locally is staggering, especially considering that the spaceport can eventually serve as the country’s takeoff point for passenger jets capable of flying at supersonic and hypersonic speeds."

Austin and Dallas also earned spots on the World's Best Cities list for 2024, but only one took a weighty tumble from the previous year's rankings. Dallas fell from No. 47 in last year's report to its current rank as No. 66.

Austin maintained its position as No. 43 for the second consecutive year, but the report suggests Houston is a much bigger player than what others have been led to believe about the Texas capital.

"Austin may get the attention, but the promise of the Lone Star State drawing Californians and New Yorkers is quietly being fulfilled in Houston," the report said.

The top 10 best cities in the world, according to Resonance Consultancy, are:

  • No. 1 – London, United Kingdom
  • No. 2 – Paris, France
  • No. 3 – New York, New York
  • No. 4 – Tokyo, Japan
  • No. 5 – Singapore
  • No. 6 – Dubai, United Arab Emirates
  • No. 7 – San Francisco, California
  • No. 8 – Barcelona, Spain
  • No. 9 – Amsterdam, Netherlands
  • No. 10 – Seoul, South Korea
The full list of cities and the report's methodology can be found on worldsbestcities.com.

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This article originally ran on CultureMap.

Houston software co. secures $39M in financing, launches latest product upgrade

fresh funding

A Houston software-as-a-service company has secured $39 million in financing and announced its latest upgrade to its platform.

Graylog, which has created an innovative platform for cybersecurity and IT operations, raised equity funding with participation from new investor Silver Lake Waterman and existing investors Piper Sandler Merchant Banking and Harbert Growth Partners leading the round.

“The growth we are seeing globally is a response to our team’s focus on innovation, a superior user experience, low total cost of ownership, and strong execution from our Go-To-Market and Customer Success teams,” Andy Grolnick, CEO of Graylog, says in a news release. “We expect this momentum to continue as Graylog expands its reach and raises its profile in the security market.”

Grolnick tells TechCrunch that the financing includes $9 million in a series C extension round and $30 million in “flex debt.” The company closed its series C in 2021.

In its news release, Graylog reported a 67 percent increase in new bookings as of last quarter. The company also reported the acquisition of Resurface.io’s API security platform in July, growth in Europe and Asia Pacific, and availability on AWS Marketplace among its list of recent growth opportunities.

“Graylog’s solid growth underscores the strength of the extensible Threat Detection & Incident Response platform the team has built to help customers detect and respond to cybersecurity threats and leverage advanced log management for operational effectiveness,” Shawn O’Neill, managing director and group head of Silver Lake Waterman, says in the release. “We look forward to partnering with Graylog to help enable their continued success.”

The financing was announced October 31, and today, November 1, Graylog announced version 5.2 of its platform technology for its users.

The company plans to use its funding on product development and differentiation, scaling, and as a bridge to profitability, which Grolnick tells TechCrunch is just around the corner.

“Graylog’s product-led growth model, combined with its focus on customer success, continues to be an attractive combination that bodes well for its future," Bob Rinek, managing director with Piper Sandler Merchant Banking, says in the release. "We’re also excited about Graylog’s expansion into the API Security space to help its customers defend this vulnerable attack surface."

Originally founded in 2009 by Lennart Koopmann as an open source project, Houston-based VC firm Mercury invested in the company in 2014. Grolnick has served as CEO since 2020.

Houston-based Graylog announced new financing as well as a new version of its software this week. Photo via graylog.org

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