Fram2, operated by SpaceX, is targeting to launch Monday, March 31. The crew will conduct six TRISH experiments on board. Photo courtesy TRISH.

Houston's Translational Research Institute for Space Health, or TRISH, will send its latest experiments into space aboard the Fram2 mission, the first all-civilian human spaceflight mission to launch over the Earth’s polar regions.

Fram2, operated by SpaceX, is targeting to launch Monday, March 31, at NASA’s Kennedy Space Center in Florida. The crew of four is expected to spend several days in polar orbit aboard the SpaceX Dragon spacecraft in low Earth orbit. TRISH’s research projects are among 22 experiments that the crew will conduct onboard.

The crew's findings will add to TRISH's Enhancing eXploration Platforms and ANalog Definition, or EXPAND, program and will be used to help enhance human health and performance during spaceflight missions, including missions to the moon and Mars, according to a release from TRISH.

“The valuable space health data that will be captured during Fram2 will advance our understanding of how humans respond and adapt to the stressors of space,” Jimmy Wu, TRISH deputy director and chief engineer and assistant professor in Baylor’s Center for Space Medicine, said in the release. “Thanks to the continued interest in furthering space health by commercial space crews, each human health research project sent into orbit brings us closer to improving crew member well-being aboard future spaceflight missions.”

The six TRISH projects on Fram2 include:

  • Cognitive and Physiologic Responses in Commercial Space Crew on Short-Duration Missions, led by Dr. Mathias Basner at the University of Pennsylvania Perelman School of Medicine. The crew will wear a Garmin smartwatch and a BioIntelliSense BioButton® medical grade device to track cognitive performance, including memory, spatial orientation, and attention before, during, and after the mission.
  • Otolith and Posture Evaluation II, led by Mark Shelhamer at Johns Hopkins University. The experiment will look at how astronauts’ eyes sense and respond to motion before and after spaceflight to better understand motion sickness in space.
  • REM and CAD Radiation Monitoring for Private Astronaut Spaceflight, led by Stuart George at NASA Johnson Space Center. This experiment will test space radiation exposure over the Earth’s north and south poles and how this impacts crew members.
  • Space Omics + BioBank, led by Richard Gibbs and Harsha Doddapaneni at Baylor College of Medicine. The experiment will use Baylor’s Human Genome Sequencing Center's Genomic Evaluation of Space Travel and Research program to gain insights from pre-flight and post-flight samples from astronauts.
  • Standardized research questionnaires, led by TRISH. The test asks a set of standardized research questionnaires for the crew to collect data on their sleep, personality, health history, team dynamics and immune-related symptoms.
  • Sensorimotor adaptation, led by TRISH. The project collects data before and after flight to understand sensorimotor abilities, change and recovery time to inform future missions to the moon.

TRISH, which is part of BCM’s Center for Space Medicine with partners Caltech and MIT, has launched experiments on numerous space missions to date, including Blue Origin's New Shepard rocket last November and Axiom Space's Ax-3 mission to the International Space Station last January.

Houston-based health tech organization had experiments on Blue Origin's last mission. Photo courtesy of Blue Origin

Houston space health nonprofit launches first experiments onboard Blue Origin mission

all aboard

Houston's Translational Research Institute for Space Health, or TRISH, conducted cutting-edge research onboard Blue Origin's New Shepard rocket that launched Friday, November 22.

The NS-28 mission sent private astronauts on an 11-minute suborbital journey past the recognized boundary of space known as the Kármán line, according to Blue Origin's website. While on board, astronauts wore a medical-grade BioButton device, known as a BioIntelliSense, that monitored vital signs and biometric readings.

The findings will add to TRISH's Enhancing eXploration Platforms and ANalog Definition, or EXPAND, program and were the first data sets captured from a suborbital flight.

“This initiative enables TRISH to further our research in space medicine by collecting valuable human health data,” Jimmy Wu, TRISH deputy director and chief engineer and assistant professor at Baylor, said in a statement. “New data from suborbital flights builds our understanding of how the human body responds to spaceflight. This holistic view is key in keeping humans healthy and safe in space.”

The experiments were also TRISH's first on a Blue Origin mission.

TRISH, which is part of BCM’s Center for Space Medicine with partners Caltech and MIT, has launched experiments on numerous space missions to date, with each contributing to its EXPAND platform, which compiles research on human health while in space.

In January, TRISH launched six experiments onboard Houston-based Axiom Space's third private astronaut mission to the International Space Station, known as Ax-3. Prior to that, it also sent experiments on board the Ax-2 in May 2023. The research considered topics ranging from changes in astronauts memory before and after space travel to sleep and motor skills.

TRISH also launched experiments onboard SpaceX's Polaris Dawn mission this fall and on the Inspiration4 all-civilian mission to orbit in 2021.

TRISH published its findings from the Inspiration4 mission in the journal Nature this summer. The study showed that "short-duration missions do not pose a significant health risk" to humans onboard. Read more about the team's findings here.

Earlier this month, TRISH announced the initial selection for its Space Health Ingress Program (SHIP) solicitation. Photo via BCM.edu

Houston organization selects research on future foods in space health to receive $1M in funding

research and development

What would we eat if we were forced to decamp to another planet? The most immediate challenges faced by the food industry and astronauts exploring outside Earth are being addressed by The Translational Research Institute for Space Health (TRISH) at Baylor College of Medicine’s Center for Space Medicine’s newest project.

Earlier this month, TRISH announced the initial selection for its Space Health Ingress Program (SHIP) solicitation. Working with California Institute of Technology and Massachusetts Institute of Technology, the Baylor-based program chose “Future Foods for Space: Mobilizing the Future Foods Community to Accelerate Advances in Space Health,” led by Dr. Denneal Jamison-McClung at the University of California, Davis.

“TRISH is bringing in new ideas and investigators to propel space health research,” says Catherine Domingo, TRISH operations lead and research administration associate at Baylor College of Medicine, in the release. “We have long believed that new researchers with fresh perspectives drive innovation and advance human space exploration and SHIP builds on TRISH’s existing efforts to recruit and support new investigators in the space health research field, potentially yielding and high-impact ideas to protect space explorers.”

The goal of the project is to develop sustainable food products and ingredients that could fuel future space travelers on long-term voyages, or even habitation beyond our home planet.

Jamison-McClung and her team’s goal is to enact food-related space health research and inspire the community thereof by mobilizing academic and food-industry researchers who have not previously engaged with the realm of space exploration. Besides growing and developing food products, the project will also address production, storage, and delivery of the nutrition created by the team.

To that end, Jamison-McClung and her recruits will receive $1 million over the course of two years. The goal of the SHIP solicitation is to work with first-time NASA investigators, bringing new minds to the forefront of the space health research world.

“As we look to enable safer space exploration and habitation for humans, it is clear that food and nutrition are foundational,” says Dr. Asha S. Collins, chair of the SHIP advisory board, in a press release. “We’re excited to see how accelerating innovation in food science for space health could also result in food-related innovations for people on Earth in remote areas and food deserts.”

TRISH is sending six research projects onboard Axiom Space's next mission, which is expected to launch in January. Photo via bcm.com

Space health nonprofit to send 6 more experiments to space on Houston company's next mission

medicine in orbit

A Houston organization announced that it plans to launch six more experiments into space next year that look to learn more about everything from motion sickness to genome alterations during space travel.

The Translational Research Institute for Space Health, or TRISH, which is part of BCM’s Center for Space Medicine, will team up once more with Houston-based Axiom Space on its third private astronaut mission to the International Space Station, Ax-3, which is expected to launch in January. TRISH also sent experiments on Axiom's Ax-2 mission that launched in May.

The experiments are part of TRISH's Enhancing eXploration Platforms and Analog Definition (EXPAND) program, which aims "to help humans thrive on future space missions," according to a release.

“Our commercial spaceflight partners such as Axiom Space are instrumental to cutting-edge research, including these projects designed to reveal how the human body and mind function in the extreme environment of space,” Dr. Emmanuel Urquieta, TRISH chief medical officer, EXPAND program lead and assistant professor in the Center for Space Medicine at Baylor. “This work represents an important step in our journey to understand the body's response to challenging conditions, which is critical for improving human health both here on Earth and on future long-duration missions, including to the Moon and Mars.”

The six project onboard Ax-3 include:

  • Cognitive and Physiologic Responses in Commercial Space Crew on Short-Duration Missions, Mathias Basner, M.D., Ph.D., M.S., University of Pennsylvania Perelman School of Medicine: Basner’s team will track spaceflight participants’ memory, abstraction, spatial orientation, emotion recognition, risk decision-making and sustained attention before and after space travel
  • Otolith and Posture Evaluation II, Mark Shelhamer, Sc.D., Johns Hopkins University: Shelhamer's team will study how inner ears and eyes sense and respond to motion before and immediately after spaceflight to predict who is likely to develop space motion sickness.
  • Space Omics + BioBank, Richard Gibbs, Ph.D., Baylor College of Medicine: Gibbs’ team will gather biological specimens from astronauts before and after their mission to assess the effects of spaceflight on the human body at the genomic level.
  • SANS Surveillance, TRISH: The institute will study Spaceflight Associated Neuro-Ocular Syndrome by collecting vision function data during the ground phases of the mission.
  • Standardized research questionnaires, TRISH: The institute will gather contextual and qualitative data points for its EXPAND research database related to sleep, personality, health history, team dynamics and immune-related symptoms.
  • Sensorimotor adaptation, TRISH: The institute will collect data on how spaceflight participants' ability to stand, balance and have full body control.

Ax-3 is Axiom's third commercial astronaut mission to the ISS, which the company announced in March. The crew, which includes Commander Michael López-Alegría, Pilot Walter Villadei, and Mission Specialists Alper Gezeravcı and Marcus Wandt, will spend 14 days on the ISS. The mission will launch from NASA’s Kennedy Space Center in Florida aboard a SpaceX Dragon spacecraft.

Axiom also has plans for its fourth private mission, Ax-4, which it announced in August.

In addition to the partnership with Axiom, TRISH also announced late last month that it has made a new agreement with the Australian Antarctic Division's Polar Medicine Unit. The collaboration will nominate pilot projects that focus on challenges associated with extreme isolation, which have applications in long-duration space travel to the Moon and Mars.

“Our international collaboration with the AAD will extract insights to benefit all future astronauts, as well as other explorers of extreme environments,” said Dr. Dorit Donoviel, associate professor in the Center for Space Medicine at Baylor and TRISH executive director. “This agreement marks the beginning of yet another exciting venture into space health research for TRISH, and we look forward to collaborating with the AAD to advance our shared goal of promoting safe human exploration.”

In March, TRISH also announced an international agreement with the Korea National Institute of Health. The two organizations plan to collaborate on research related to mental health issues due to space travel, the challenges of food supply in deep space, the negative effects of space radiation and en-suite medical care for long-duration space travel.

TRISH is also slated to launch nine experiments on board SpaceX's Polaris Dawn mission, which is now expected to launch no earlier than 2024. The research aboard Polaris Dawn is intended to complement research supported by TRISH on the Inspiration4 all-civilian mission to orbit.
TRISH, or the Translational Institute of Space Health, has named three fellows to its new program. Photo via bcm.edu

Houston space health research organization names 3 fellows for bioastronautics program

hello fellows

Three Texas scientists have been selected for a Houston organization's prestigious program focused on space health.

TRISH, or the Translational Research Institute for Space Health, which is based out of Houston-based Baylor College of Medicine, has announced its selections for the TRISH 2023 fellowship. The program, announced last fall, is in partnership with California Institute of Technology and Massachusetts Institute of Technology.

“Supporting the next generation of space health researchers ensures that we will have the best possible data to make evidence-based decisions about managing human systems risk for exploration class missions,” says Dr. Jennifer Fogarty, TRISH’s chief scientific officer, in a news release. “By investing in TRISH postdoctoral fellows, we’re investing in future experts who will strive to solve the complex problems and risks associated with human space exploration. We are thrilled to welcome these accomplished early-career scientists to the TRISH community.”

The three selected postdoctoral fellows are focused on researching within space health — specifically reducing the health risks associated with spaceflight. They will receive a two-year salary stipend and participate in TRISH’s Academy of Bioastronautics, a mentorship community for space health professionals.

“Pursuing my postdoctoral training at TRISH has accelerated my career and expanded my research portfolio, enabling me to make new connections and become a more well-rounded scientist,” says Dr. Evan Buettmann, a TRISH third-year postdoctoral fellow at Virginia Commonwealth University, in the release. “Having completed my Ph.D. in bone regeneration, I didn’t initially anticipate that my studies would lead me to an academic career in space health. TRISH stood out to me as an excellent place to complete my postdoctoral training, as it’s at the cutting edge of both space science and medicine and offers extensive mentorship and leadership opportunities.”

This 2023 cohort of fellows include:

  • Stephanie Dudzinski, M.D., Ph.D. Her research focuses on extending healthy life in space by characterizing radiation-induced pro-inflammatory response and enhancing wound repair and recovery with radiation- mitigating thrombin peptide. Her mentor is Steven Frank, M.D., of the University of Texas MD Anderson Cancer Center.
  • Adrien Robin, Ph.D., who is looking at the effect of deconditioning on-gravitational dose-response curves for cardiovascular and ocular variables in men and women and is being mentored by Ana Diaz Artiles, Ph.D., Texas A&M Engineering Experiment Station.
  • Katherine Wozniak, Ph.D., who is defining gut microbial changes to space-like radiation to develop a radiation-resistant microbiome. Her mentor is Robert Britton, Ph.D., of Baylor College of Medicine.
In addition to supporting scientists through its fellowship program, TRISH is actively conducting research aboard commercial space flights — most recently with Axiom Space's Ax-2 mission..
This week's roundup of Houston innovators includes Emmanuel Urquieta of TRISH, Ariel Jones of Qualtrics XM, and Lawson Gow of Pokatok. Photos courtesy

3 Houston innovators to know this week

WHO'S WHO

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from space health research to sports tech — recently making headlines in Houston innovation.


Dr. Emmanuel Urquieta, chief medical officer of TRISH

Emmanuel Urquieta, chief medical officer of TRISH, joins the Houston Innovators Podcast. Photo via LinkedIn

Since 2021, the Translational Research Institute for Space Health has conducted its research on four missions — which has meant an unparalleled access to space health data for TRISH.

“We really saw the value of implementing research in civilians because they are different from your traditional government astronaut,” Dr. Emmanuel Urquieta, chief medical officer for TRISH, says on the Houston Innovators Podcast. “In civilians, you see a more diverse population.”

Urquieta says TRISH's experiments on these missions all fall within a few pillars of space health, including space's effects on sensory motor skills, like balance and motion sickness, as well as mental health, environmental data from the vehicles, vital monitoring, and more. Read more.

Ariel Jones, head of health care provider solution strategy for Qualtrics XM

As the health care industry continues to evolve, experience management technology will play an increasingly important role in addressing health equity gaps and improving the health and well-being of patients across the globe. Photo courtesy

In a guest column for InnovationMap, Ariel Jones, head of health care provider solution strategy for Qualtrics XM, addresses inequalities in health care — and how technology, specifical experience management tech, can help bridge the gap.

"As the health care industry continues to evolve, experience management technology will play an increasingly important role in addressing health equity gaps and improving the health and well-being of patients across the globe," she writes. Read more.

Lawson Gow, co-founder of Pokatok

A new sports festival is headed to Houston next year. Photo courtesy of Pokatok

Pokatok, the recently announced, four-day sports festival is slated to take place April 4-7, 2024.

“Pokatok will not only be the largest gathering of the entire sports tech ecosystem, it will also be a true fan festival for sports enthusiasts,” says Gow in the news release. “Everyone speaks the language of sport, it’s an incredibly powerful unifier of our society, and this festival will bring together people from around the world to experience hundreds of events revolving around the new and the next in sport.”

The festival, which has secured support from Houston First, the Greater Houston Partnership, and the Harris County Houston Sports Authority to put on the event, will feature two tracks — one focused on sports innovation and the other surrounding a fan experience. Pokatok X will include an expo and showcase focused on sports innovation, bringing together startups, investors, accelerators, athletes, and industry experts to dive into sports tech. Read more.

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5+ must-know application deadlines for Houston innovators

apply now

Editor's note: As 2026 ramps up, the Houston innovation scene is looking for the latest groups of innovative startups that'll make an impact. A number of accelerators and competitions have opened applications. Read below to see which might be a good fit for you or your venture. And take careful note of the deadlines. Please note: this article may be updated to include additional information and programs.

Did we miss an accelerator or competition accepting applications? Email innoeditor@innovationmap.com for editorial consideration.

2026 HCC Business Plan Competition

Deadline: Jan. 26

Details: HCC’s annual Business Plan Competition (BPC) is an opportunity for proposed, startup and existing entrepreneurs to develop focused plans to start or grow their businesses. Accepted teams will be announced and training will begin in late February and run through early June, with six free, three-hour training sessions. Advising will be provided to each accepted team. Applicants can apply as a team of up to five persons. Finalists will present to to gudges on May 27, 2026. Last year, $26,000 was awarded in seed money to the top five teams. In-kind prizes were also awarded to all graduating teams including free products, services and memberships, with an estimated in-kind value totaling $147,000. Find more information here.

University of Houston Technology Bridge Innov8 Hub (Spring 2026)

Deadline: Jan . 30

Details: UHTB Innov8 Hub’s immersive, 12-week startup acceleration program designed to help early-stage founders launch and scale their technology startups. Selected participants will gain access to expert mentors and advisors, collaborate with a cohort of peers, and compete for cash prizes during our final pitch event. The cohort begins Feb. 16, 2026. The program culminates in Pitch Day, where participants present their ventures to an audience of investors and partners from across the UH innovation ecosystem. Find more information here.

Rice Business Plan Competition 2026

Deadline: Jan. 31

Details: The Rice Business Plan Competition, hosted by the Rice Alliance for Technology and Entrepreneurship, gives collegiate entrepreneurs real-world experience to pitch their startups, enhance their business strategy and learn what it takes to launch a successful company. Forty-two teams will compete for more than $1 million in cash, investments and prizes on April 9-11, 2026. Find more information here.

Rice Veterans Business Battle 2026

Deadline: Jan. 31

Details: The Rice Veterans Business Battle is one of the nation’s largest pitch competitions for veteran-led startups, providing founders with mentorship, exposure to investors and the opportunity to compete for non-dilutive cash prizes. The event has led to more than $10 million of investments since it began in 2015. Teams will compete April 8-9, 2026. Find more information here.

TEX-E Fellows Application 2026-2027

Deadline: Feb. 10

Details: The TEX‑E Fellowship is a hands-on program designed for students interested in energy, climate, and entrepreneurship across Texas. It connects participants with industry mentors, startup founders, investors and academic leaders while providing practical, "real-world" experience in customer discovery, business modeling, and energy-transition innovation. Fellows gain access to workshops, real-world projects, and a statewide network shaping the future of energy and climate solutions. Participants must be a student at PVAMU, UH, UT Austin, Rice University, MIT or Texas A&M. Find more information here.

Greentown Go Make 2026

Deadline: March 10

Details: Greentown Go Make 2026 is an open-innovation program with Shell and Technip Energies. The six-month program is advancing industrial decarbonization by accelerating catalytic innovations. Selected startups will gain access to a structured platform to engage leadership from Shell and Technip Energies and explore potential partnership outcomes, including pilots and demonstrations. They’ll also receive networking opportunities, partnership-focused programming, and marketing visibility throughout the program. The cohort will be selected in May. Find more information here.

Houston startups closed $1.75 billion in 2025 VC funding, says report

by the numbers

Going against national trends, Houston-area startups raised 7 percent less venture capital last year than they did in 2024, according to the new PitchBook-NVCA Venture Monitor report.

The report shows local startups collected $1.75 billion in venture capital in 2025, down from $1.89 billion the previous year.

Houston-based geothermal energy company Fervo Energy received a big chunk of the region’s VC funding last year. Altogether, the startup snagged $562 million in investments, as well as a $60 million extension of an existing loan and $45.6 million in debt financing. The bulk of the 2025 haul was a $462 million Series E round.

In the fourth quarter of last year, Houston-area VC funding totaled $627.68 million. That was a 22 percent drop from $765.03 million during the same period in 2024. Still, the Q4 total was the biggest quarterly total in 2025.

Across the country, startups picked up $339.4 trillion in VC funding last year, a 59 percent increase from $213.2 trillion in 2024, according to the report. Over the last 10 years, only the VC total in 2021 ($358.2 trillion) surpassed the total from 2025.

Nationwide, startups in the artificial intelligence and machine learning sector accounted for the biggest share of VC funding (65.4 percent) in 2025, followed by software-as-a-service (SaaS), big data, manufacturing, life sciences and healthtech, according to the report.

“Despite an overall lack of new fundraising and a liquidity market that did not shape up as hoped in 2025, deal activity has begun a phase of regrowth, with deal count estimates showing increases at each stage, and deal value, though concentrated in a small number of deals, falling just [8 percent] short of the 2021 figure,” the report reads.

Sandbox VR brings new gaming center to Houston's tech-savvy population

Get In The Game

Sandbox VR, a futuristic, full-body virtual reality gaming experience, has announced it will enter the Houston market this month, opening its first local gaming center on January 23.

"Houston's reputation as a hub for innovation and technology makes it a perfect fit for Sandbox VR," said Steve Zhao, CEO and founder of Sandbox VR, in a statement. "The city's diverse, tech-savvy population and strong entertainment culture create an ideal environment for our immersive VR experiences. LOL Entertainment continues to exceed our expectations as a partner, and we're excited to bring our cutting-edge virtual reality gaming to Texas's largest city."

The new gaming center opens Friday, January 23 at 797 Sorella Court in CityCentre.

One of the games that stands out is the Stranger Things: Catalyst game, based on the blockbuster Netflix television series. Groups of one to six players will be dropped into the sinister Hawkins Lab and the mysterious Upside Down to fight Demogorgons and other monsters. The game features Matthew Modine reprising his role as Dr. Martin "Papa" Brenner, who imbues players with psychic powers.

Other games include the supernatural pirate title The Curse of Davy Jones and other Netflix tie-ins based on Zack Snyder's Rebel Moon and Squid Game. Sandbox VR offers fully-immersive group play activities that range from combat to puzzle solving for a variety of age groups.

The opening of Sandbox VR is another part of the expansion of LOL Entertainment, who touts itself as one of the pre-eminent hosts of immersive and gaming experiences in the U.S. Sandbox VR will be their first entry into the Houston market, with another immersive group adventure game, Time Mission, set to open at the the Marq'E Entertainment District later this year.

“Bringing Sandbox VR to CityCentre Houston is a big milestone for LOL Entertainment, for Sandbox VR, and for this market,” said Rob Cooper, CEO of LOL Entertainment. “Houston is a fast-growing, experience-driven city, and we’re excited to give locals and visitors a truly immersive, social gaming destination that you can’t replicate anywhere.”

Presale tickets for the grand opening of Sandbox VR are available here. Standard pricing is $55-$65 per event, but Sandbox VR is running a special for 30 percent off with code OPEN30 for those who purchase before Thursday, January 22. Presale buyers are also entered into a drawing for free Sandbox VR for one year.

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This article originally appeared on CultureMap.com.