Earlier this month, TRISH announced the initial selection for its Space Health Ingress Program (SHIP) solicitation. Photo via BCM.edu

What would we eat if we were forced to decamp to another planet? The most immediate challenges faced by the food industry and astronauts exploring outside Earth are being addressed by The Translational Research Institute for Space Health (TRISH) at Baylor College of Medicine’s Center for Space Medicine’s newest project.

Earlier this month, TRISH announced the initial selection for its Space Health Ingress Program (SHIP) solicitation. Working with California Institute of Technology and Massachusetts Institute of Technology, the Baylor-based program chose “Future Foods for Space: Mobilizing the Future Foods Community to Accelerate Advances in Space Health,” led by Dr. Denneal Jamison-McClung at the University of California, Davis.

“TRISH is bringing in new ideas and investigators to propel space health research,” says Catherine Domingo, TRISH operations lead and research administration associate at Baylor College of Medicine, in the release. “We have long believed that new researchers with fresh perspectives drive innovation and advance human space exploration and SHIP builds on TRISH’s existing efforts to recruit and support new investigators in the space health research field, potentially yielding and high-impact ideas to protect space explorers.”

The goal of the project is to develop sustainable food products and ingredients that could fuel future space travelers on long-term voyages, or even habitation beyond our home planet.

Jamison-McClung and her team’s goal is to enact food-related space health research and inspire the community thereof by mobilizing academic and food-industry researchers who have not previously engaged with the realm of space exploration. Besides growing and developing food products, the project will also address production, storage, and delivery of the nutrition created by the team.

To that end, Jamison-McClung and her recruits will receive $1 million over the course of two years. The goal of the SHIP solicitation is to work with first-time NASA investigators, bringing new minds to the forefront of the space health research world.

“As we look to enable safer space exploration and habitation for humans, it is clear that food and nutrition are foundational,” says Dr. Asha S. Collins, chair of the SHIP advisory board, in a press release. “We’re excited to see how accelerating innovation in food science for space health could also result in food-related innovations for people on Earth in remote areas and food deserts.”

TRISH is sending six research projects onboard Axiom Space's next mission, which is expected to launch in January. Photo via bcm.com

Space health nonprofit to send 6 more experiments to space on Houston company's next mission

medicine in orbit

A Houston organization announced that it plans to launch six more experiments into space next year that look to learn more about everything from motion sickness to genome alterations during space travel.

The Translational Research Institute for Space Health, or TRISH, which is part of BCM’s Center for Space Medicine, will team up once more with Houston-based Axiom Space on its third private astronaut mission to the International Space Station, Ax-3, which is expected to launch in January. TRISH also sent experiments on Axiom's Ax-2 mission that launched in May.

The experiments are part of TRISH's Enhancing eXploration Platforms and Analog Definition (EXPAND) program, which aims "to help humans thrive on future space missions," according to a release.

“Our commercial spaceflight partners such as Axiom Space are instrumental to cutting-edge research, including these projects designed to reveal how the human body and mind function in the extreme environment of space,” Dr. Emmanuel Urquieta, TRISH chief medical officer, EXPAND program lead and assistant professor in the Center for Space Medicine at Baylor. “This work represents an important step in our journey to understand the body's response to challenging conditions, which is critical for improving human health both here on Earth and on future long-duration missions, including to the Moon and Mars.”

The six project onboard Ax-3 include:

  • Cognitive and Physiologic Responses in Commercial Space Crew on Short-Duration Missions, Mathias Basner, M.D., Ph.D., M.S., University of Pennsylvania Perelman School of Medicine: Basner’s team will track spaceflight participants’ memory, abstraction, spatial orientation, emotion recognition, risk decision-making and sustained attention before and after space travel
  • Otolith and Posture Evaluation II, Mark Shelhamer, Sc.D., Johns Hopkins University: Shelhamer's team will study how inner ears and eyes sense and respond to motion before and immediately after spaceflight to predict who is likely to develop space motion sickness.
  • Space Omics + BioBank, Richard Gibbs, Ph.D., Baylor College of Medicine: Gibbs’ team will gather biological specimens from astronauts before and after their mission to assess the effects of spaceflight on the human body at the genomic level.
  • SANS Surveillance, TRISH: The institute will study Spaceflight Associated Neuro-Ocular Syndrome by collecting vision function data during the ground phases of the mission.
  • Standardized research questionnaires, TRISH: The institute will gather contextual and qualitative data points for its EXPAND research database related to sleep, personality, health history, team dynamics and immune-related symptoms.
  • Sensorimotor adaptation, TRISH: The institute will collect data on how spaceflight participants' ability to stand, balance and have full body control.

Ax-3 is Axiom's third commercial astronaut mission to the ISS, which the company announced in March. The crew, which includes Commander Michael López-Alegría, Pilot Walter Villadei, and Mission Specialists Alper Gezeravcı and Marcus Wandt, will spend 14 days on the ISS. The mission will launch from NASA’s Kennedy Space Center in Florida aboard a SpaceX Dragon spacecraft.

Axiom also has plans for its fourth private mission, Ax-4, which it announced in August.

In addition to the partnership with Axiom, TRISH also announced late last month that it has made a new agreement with the Australian Antarctic Division's Polar Medicine Unit. The collaboration will nominate pilot projects that focus on challenges associated with extreme isolation, which have applications in long-duration space travel to the Moon and Mars.

“Our international collaboration with the AAD will extract insights to benefit all future astronauts, as well as other explorers of extreme environments,” said Dr. Dorit Donoviel, associate professor in the Center for Space Medicine at Baylor and TRISH executive director. “This agreement marks the beginning of yet another exciting venture into space health research for TRISH, and we look forward to collaborating with the AAD to advance our shared goal of promoting safe human exploration.”

In March, TRISH also announced an international agreement with the Korea National Institute of Health. The two organizations plan to collaborate on research related to mental health issues due to space travel, the challenges of food supply in deep space, the negative effects of space radiation and en-suite medical care for long-duration space travel.

TRISH is also slated to launch nine experiments on board SpaceX's Polaris Dawn mission, which is now expected to launch no earlier than 2024. The research aboard Polaris Dawn is intended to complement research supported by TRISH on the Inspiration4 all-civilian mission to orbit.
TRISH, or the Translational Institute of Space Health, has named three fellows to its new program. Photo via bcm.edu

Houston space health research organization names 3 fellows for bioastronautics program

hello fellows

Three Texas scientists have been selected for a Houston organization's prestigious program focused on space health.

TRISH, or the Translational Research Institute for Space Health, which is based out of Houston-based Baylor College of Medicine, has announced its selections for the TRISH 2023 fellowship. The program, announced last fall, is in partnership with California Institute of Technology and Massachusetts Institute of Technology.

“Supporting the next generation of space health researchers ensures that we will have the best possible data to make evidence-based decisions about managing human systems risk for exploration class missions,” says Dr. Jennifer Fogarty, TRISH’s chief scientific officer, in a news release. “By investing in TRISH postdoctoral fellows, we’re investing in future experts who will strive to solve the complex problems and risks associated with human space exploration. We are thrilled to welcome these accomplished early-career scientists to the TRISH community.”

The three selected postdoctoral fellows are focused on researching within space health — specifically reducing the health risks associated with spaceflight. They will receive a two-year salary stipend and participate in TRISH’s Academy of Bioastronautics, a mentorship community for space health professionals.

“Pursuing my postdoctoral training at TRISH has accelerated my career and expanded my research portfolio, enabling me to make new connections and become a more well-rounded scientist,” says Dr. Evan Buettmann, a TRISH third-year postdoctoral fellow at Virginia Commonwealth University, in the release. “Having completed my Ph.D. in bone regeneration, I didn’t initially anticipate that my studies would lead me to an academic career in space health. TRISH stood out to me as an excellent place to complete my postdoctoral training, as it’s at the cutting edge of both space science and medicine and offers extensive mentorship and leadership opportunities.”

This 2023 cohort of fellows include:

  • Stephanie Dudzinski, M.D., Ph.D. Her research focuses on extending healthy life in space by characterizing radiation-induced pro-inflammatory response and enhancing wound repair and recovery with radiation- mitigating thrombin peptide. Her mentor is Steven Frank, M.D., of the University of Texas MD Anderson Cancer Center.
  • Adrien Robin, Ph.D., who is looking at the effect of deconditioning on-gravitational dose-response curves for cardiovascular and ocular variables in men and women and is being mentored by Ana Diaz Artiles, Ph.D., Texas A&M Engineering Experiment Station.
  • Katherine Wozniak, Ph.D., who is defining gut microbial changes to space-like radiation to develop a radiation-resistant microbiome. Her mentor is Robert Britton, Ph.D., of Baylor College of Medicine.
In addition to supporting scientists through its fellowship program, TRISH is actively conducting research aboard commercial space flights — most recently with Axiom Space's Ax-2 mission..
This week's roundup of Houston innovators includes Emmanuel Urquieta of TRISH, Ariel Jones of Qualtrics XM, and Lawson Gow of Pokatok. Photos courtesy

3 Houston innovators to know this week

WHO'S WHO

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from space health research to sports tech — recently making headlines in Houston innovation.


Dr. Emmanuel Urquieta, chief medical officer of TRISH

Emmanuel Urquieta, chief medical officer of TRISH, joins the Houston Innovators Podcast. Photo via LinkedIn

Since 2021, the Translational Research Institute for Space Health has conducted its research on four missions — which has meant an unparalleled access to space health data for TRISH.

“We really saw the value of implementing research in civilians because they are different from your traditional government astronaut,” Dr. Emmanuel Urquieta, chief medical officer for TRISH, says on the Houston Innovators Podcast. “In civilians, you see a more diverse population.”

Urquieta says TRISH's experiments on these missions all fall within a few pillars of space health, including space's effects on sensory motor skills, like balance and motion sickness, as well as mental health, environmental data from the vehicles, vital monitoring, and more. Read more.

Ariel Jones, head of health care provider solution strategy for Qualtrics XM

As the health care industry continues to evolve, experience management technology will play an increasingly important role in addressing health equity gaps and improving the health and well-being of patients across the globe. Photo courtesy

In a guest column for InnovationMap, Ariel Jones, head of health care provider solution strategy for Qualtrics XM, addresses inequalities in health care — and how technology, specifical experience management tech, can help bridge the gap.

"As the health care industry continues to evolve, experience management technology will play an increasingly important role in addressing health equity gaps and improving the health and well-being of patients across the globe," she writes. Read more.

Lawson Gow, co-founder of Pokatok

A new sports festival is headed to Houston next year. Photo courtesy of Pokatok

Pokatok, the recently announced, four-day sports festival is slated to take place April 4-7, 2024.

“Pokatok will not only be the largest gathering of the entire sports tech ecosystem, it will also be a true fan festival for sports enthusiasts,” says Gow in the news release. “Everyone speaks the language of sport, it’s an incredibly powerful unifier of our society, and this festival will bring together people from around the world to experience hundreds of events revolving around the new and the next in sport.”

The festival, which has secured support from Houston First, the Greater Houston Partnership, and the Harris County Houston Sports Authority to put on the event, will feature two tracks — one focused on sports innovation and the other surrounding a fan experience. Pokatok X will include an expo and showcase focused on sports innovation, bringing together startups, investors, accelerators, athletes, and industry experts to dive into sports tech. Read more.

Emmanuel Urquieta, chief medical officer of TRISH, joins the Houston Innovators Podcast. Photo via LinkedIn

Houston innovator on the importance of commercial missions for the future of space health research

HOUSTON INNOVATORS PODCAST EPISODE 189

With the rise of commercial space flight, researchers have increased access to space health data that's key to the future of the industry as a whole. The organization that's conducting this valuable research is based right in Houston's Texas Medical Center.

TRISH, or the Translational Research Institute for Space Health, is an organization based out of Baylor College of Medicine and partnered with NASA's Human Spaceflight group. As commercial space companies have emerged, TRISH has strategically aligned with these businesses to bring back health data from the civilian trips.

“Most of the research that’s done at NASA and other government agencies usually takes decades to get something that could be implemented in space or terrestrially," Dr. Emmanuel Urquieta, chief medical officer for TRISH, says on the Houston Innovators Podcast. "What we do at TRISH is something different.

"On the one hand, we look at really new technologies that are just an idea, but could be really game changing," he continues. "Then on the other hand, we look at technologies already in the market that could be tweaked to work in spaceflight.”

Since 2021, TRISH has conducted its research on four missions — Inspiration4, the first all-civilian mission to space; Axiom Mission 1, the first all civilian mission to the International Space Station; MS20, which flew two Japanese civilians to ISS; and, most recently, Axiom Mission 2, which included the first all-private crew commanded by a woman and two members of the Kingdom of Saudi Arabia's national astronaut program.

“We really saw the value of implementing research in civilians because they are different from your traditional government astronaut,” Urquieta says. “In civilians, you see a more diverse population.”

Urquieta says TRISH's experiments on these missions all fall within a few pillars of space health, including space's effects on sensory motor skills, like balance and motion sickness, as well as mental health, environmental data from the vehicles, vital monitoring, and more.

“We’ve developed a capability to collect high-priority, high-value data from these space flight participants without having to train them for long periods of time — which is a challenge, because they don’t train for years like traditional astronauts,” he explains.

The plan, Urquieta says, is to be able to share TRISH's space health data in order to more safely send humans into space. He shares more about TRISH's program and the challenges the organization faces on the show. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

A new partnership on Earth will help navigate the future of space health. Photo via NASA

Houston space research nonprofit announces new international agreement

partnership launch

Houston's Translational Research Institute for Space Health, or TRISH, has entered into an agreement with the Korea National Institute of Health to collaborate on research and discovery relating to space health.

According to a release, the organizations aim to uncover health findings that can assist in NASA's upcoming Artemis missions, as well as have Earth-bound impacts. The agreement is a Memorandum of Understanding which states that both organizations will "develop fruitful areas of cooperation for space health."

TRISH — which is affiliated with Baylor College of Medicine — and KNIH plan to collaborate on research related to mental health issues due to space travel, the challenges of food supply in deep space, the negative effects of space radiation and en-suite medical care for long-duration space travel.

“As in space, there should be no borders or boundaries to scientific discovery that benefits humankind,” Dorit Donoviel, associate professor in the Center for Space Medicine at Baylor and executive director TRISH said in a statement. “With this agreement, we will work together with the KNIH to collaborate and foster meaningful discussion with the ambition of keeping humans healthy in space and on Earth.”

TRISH announced last month that it will launch six experiments into space aboard Axiom Space's Ax-2 mission in consortium with CalTeach and MIT, which was originally targeted to launch this month.

TRISH is also slated to launch nine experiments on board SpaceX's Polaris Dawn mission, which is now expected to launch in September.

Some of the information found from these missions will become part of TRISH’s Enhancing eXploration Platforms and ANalog Definition, or EXPAND, program, which aims to boost human health on commercial space flights through its database. The program launched in 2021.
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Houston Innovation Awards to honor 2 trailblazers with posthumous recognition

top leaders

Last month, the Houston innovation community suffered the loss of two business leaders who left a significant impact on the ecosystem. In November, both individuals' careers will be recognized with Trailblazer Legacy Awards.

Every year, the Houston Innovation Awards honors a Trailblazer Award recipient for their past and future dedication to startups in Houston, and this year InnovationMap is doing approaching the award differently in light of recent events. Paul Frison, founder of the Houston Technology Center, and Scott Gale, executive director of Halliburton Labs, will receive the award posthumously. Frison died on September 5, and Gale died on September 24. The award was decided on by the 2024 judges and InnovationMap.

“I am immensely proud to honor these two remarkable individuals with the Trailblazer Award this year. It is fitting, as they represent two generations of building Houston’s ecosystem," 2023 Trailblazer Award recipient Brad Burke, managing director of the Rice Alliance and the associate vice president for industry and new ventures within Rice University's Office of Innovation, tells InnovationMap.

"Paul Frison was a pioneering leader who helped establish the Houston Technology Center and fostered the city’s tech ecosystem during the initial technology boom around the year 2000. Scott Gale, through his work at Halliburton Labs over the past five years, has been instrumental in launching Houston’s energy transition ecosystem," he continues. "Both have played pivotal roles in championing technology innovators.”

A long-time Houston businessman, Frison founded HTC in 1999 and served as its CEO and president. The organization evolved into Houston Exponential several years ago. Frison remained active within Houston innovation until 2020. Prior to HTC, he served in various executive roles at American Hospital Supply, LifeMark, ComputerCraft, and LifeCell, spending the last 50 of his years in Houston. Born in Glendale, California, he served in the Unites States Coast Guard.

"Houston's vibrant technology entrepreneurship ecosystem is the product of Paul Frison's commitment to innovation, integrity, and growth for our community," says Walter Ulrich, former president and CEO of HTC. "He is the father of Houston's tech ecosystem, CEO of one of Houston's first tech Unicorns, founder of the Houston Technology Center ranked as a top ten technology incubator by Forbes, philanthropist, veteran, and family man."

Gale helped to launch Halliburton Labs in 2020. Prior to that role, he lead global strategy initiatives for Halliburton. A Brigham Young University graduate, he received his MBA from Rice University in 2019, where he co-founded the Jones Student Association for Executives. After his graduation, he served on the the Rice Business Alumni Association Board and the Energy Advisory Board for the Rice Alliance Clean Energy Accelerator. He was also a voice actor and the co-host of two podcasts: Rice University's Owl Have You Know Podcast, which shares experiences of Rice's business community, and the Curiosity podcast, which explored optimism and curiosity with guests and co-host Brad Rossacci.

"We established the Trailblazer Award to recognize the city's innovation leaders, and Scott and Paul both more than deserve to be recognized for their contributions to Houston," Natalie Harms, editor of InnovationMap, says. "My hope is that this year's Trailblazer Legacy Awards pay tribute to their lasting impacts."

The awards will be presented at the November 14 event.

Rice researchers secure $35M federal grant to advance medical device technology

big money

Rice University has secured part of a nearly $35 million federal grant aimed at commercializing a bioelectric implant for treatment of type 2 diabetes and obesity.

The federal Advanced Research Projects Agency for Health awarded the $34.9 million grant to Rice and several other universities.

Rice’s Biotech Launch Pad will lead the effort to commercialize the self-contained, implantable Rx On-site Generation Using Electronics (ROGUE) device. ROGUE houses cells that are engineered to produce type 2 diabetes and obesity therapies in response to patients’ needs.

Carnegie Mellon University leads the team of researchers handling development and testing of ROGUE, which acts as a “living pharmacy” designed to make biologic drugs available on demand in a patient’s body.

The ROGUE initiative aims to keep the cost of this treatment significantly below the cost of other biologics-based treatments.

“ROGUE’s innovative design combines efficient biological manufacturing, long-term durability, and patient-friendly features that have the potential to transform the landscape of biologics delivery,” Omid Veiseh, professor of bioengineering and faculty director of the Rice Biotech Launch Pad, says in a news release.

Paul Wotton, an in-house entrepreneur at the university and executive director of the Rice accelerator, is helping guide ROGUE toward becoming an independent company.

“With the Biotech Launch Pad, our goal is venture creation in parallel to the groundbreaking research at Rice and its collaborating institutions,” Wotton says.

Omid Veiseh is professor of bioengineering and faculty director of the Rice Biotech Launch Pad. Photo courtesy Rice University