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5 most popular innovation stories in Houston this week

A roundup of Houston startup news, innovators to know, and more are this week's trending stories. Photo via Getty Images

Editor's note:Another week has come and gone, and it's time to round up the top headlines from the past few days. Trending Houston tech and startup news on InnovationMap included innovators to know, a guest column on attracting and retaining female tech talent, a roundup of Houston Innovation news, and more.

3 Houston innovators to know this week

This week's roundup of Houston innovators includes Stephanie Campbell of HAN and The Artemis Fund, Larry Lawson of Proxima Clinical Research, and Vanessa Wyche of the Johnson Space Center. Courtesy photos

In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from medical device development to fintech — recently making headlines in Houston innovation. Click here to continue reading.

Houston named an affordable tech city, startup hires CFO, and more local innovation news

In the latest round up of Houston innovation news you may have missed, Houston has been deemed an affordable city for tech careers, HighRadius has a new product, and more. Photo via Getty Images

It's been a busy summer for the Houston innovation ecosystem, and for this reason, local startup and tech news may have fallen through some of the cracks.

In this roundup of short stories within Houston innovation, a software company has a new game-changing product, Houston was named an affordable city for a tech career, a health tech startup has a new C-suite leader, and more. Click here to continue reading.

How to attract and retain female engineers for the Houston workforce

Female engineers are here in Houston, but let's work together to ensure they are here to stay. Photo via Christina Morillo/Pexels

As Houston continues to invest in resiliency for our growing city, a well-equipped workforce is needed to meet the demand for critical infrastructure. It is also important that in a city as diverse as Houston, the engineering and construction talent that encompasses our workforce is reflective of the city itself, aligning with our ever-changing demographics.

While women continue to make strides in the STEM field, according to Pew Research Center, women's shares in the field of engineering have inched up only slightly, from 12 percent in 1990 to 15 percent today. And while women now earn a majority of all undergraduate and advanced degrees, they remain a small share of degree earners in fields like engineering and computer science — areas where they are significantly underrepresented in the workforce. Click here to continue reading.

Houston incubator announces merger with local nonprofit

Grace Rodriguez, CEO and executive director of Impact Hub Houston, and Jeff Reichman, founder of Sketch City, have announced a partnership between their organizations. Photos courtesy

Two Houston organizations that have partnered for three years to provide a platform for innovation and ideation have announced a more formalized partnership.

Impact Hub Houston, a global impact innovation incubator, and Sketch City, a nonprofit focused on advancing technology and data in public decision making and social good, have announced the merger of Sketch City into a new initiative under Impact Hub Houston: Code for Houston.

"We're honored to continue Sketch City's work of connecting Houston's tech talent with civic innovation opportunities through Code for Houston," says Grace Rodriguez, CEO and executive director of Impact Hub Houston, in a news release. Click here to continue reading.

City of Houston's startup competition takes off with $30,000 up for grabs

Applications are now open for Liftoff Houston. Photo courtesy of the City of Houston

The applications for the 2021 Liftoff Houston Startup Business Plan Competition opened this week and local businesses have less than a month to get their submissions in for a chance to be one of three companies to take home seed funds.

"I am excited to see what business ideas and concepts this year's contestants will bring to the table," says Mayor Sylvester Turner in a news release from the city. "We are grateful for Capital One Bank's commitment to helping Houstonians make their small business dreams come true. I encourage all aspiring entrepreneurs not to miss out on this wonderful opportunity that will help move our economy and city forward." Click here to continue reading.

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Building Houston

 
 

A Rice research team is tapping into materials science to better understand Alzheimer’s disease, a UH professor is developing a treatment for hereditary vision loss, and a BCM researcher is looking at stress and brain cancer. Photo by Gustavo Raskosky/Rice University

Research, perhaps now more than ever, is crucial to expanding and growing innovation in Houston — and it's happening across the city right under our noses.

In InnovationMap's latest roundup of research news, three Houston institutions are working on life-saving health care research thanks to new technologies.

Rice University scientists' groundbreaking alzheimer's study

Angel Martí (right) and his co-authors (from left) Utana Umezaki and Zhi Mei Sonia He have published their latest findings on Alzheimer’s disease. Photo by Gustavo Raskosky/Rice University

According to the Centers for Disease Control and Prevention, Alzheimer’s disease will affect nearly 14 million people in the U.S. by 2060. A group of scientists from Rice University are looking into a peptide associated with the disease, and their study was published in Chemical Science.

Angel Martí — a professor of chemistry, bioengineering, and materials science and nanoengineering and faculty director of the Rice Emerging Scholars Program — and his team have developed a new approach using time-resolved spectroscopy and computational chemistry, according to a news release from Rice. The scientists "found experimental evidence of an alternative binding site on amyloid-beta aggregates, opening the door to the development of new therapies for Alzheimer’s and other diseases associated with amyloid deposits."

Amyloid plaque deposits in the brain are a main feature of Alzheimer’s, per Rice.

“Amyloid-beta is a peptide that aggregates in the brains of people that suffer from Alzheimer’s disease, forming these supramolecular nanoscale fibers, or fibrils” says Martí in the release. “Once they grow sufficiently, these fibrils precipitate and form what we call amyloid plaques.

“Understanding how molecules in general bind to amyloid-beta is particularly important not only for developing drugs that will bind with better affinity to its aggregates, but also for figuring out who the other players are that contribute to cerebral tissue toxicity,” he adds.

The National Science Foundation and the family of the late Professor Donald DuPré, a Houston-born Rice alumnus and former professor of chemistry at the University of Louisville, supported the research, which is explained more thoroughly on Rice's website.

University of Houston professor granted $1.6M for gene therapy treatment for rare eye disease

Muna Naash, a professor at UH, is hoping her research can result in treatment for a rare genetic disease that causes vision loss. Photo via UH.edu

A University of Houston researcher is working on a way to restore sight to those suffering from a rare genetic eye disease.

Muna Naash, the John S. Dunn Endowed Professor of biomedical engineering at UH, is expanding a method of gene therapy to potentially treat vision loss in patients with Usher Syndrome Type 2A, or USH2A, a rare genetic disease.

Naash has received a $1.6 million grant from the National Eye Institute to support her work. Mutations of the USH2A gene can include hearing loss from birth and progressive loss of vision, according to a news release from UH. Naash's work is looking at applying gene therapy — the introduction of a normal gene into cells to correct genetic disorders — to treat this genetic disease. There is not currently another treatment for USH2A.

“Our goal is to advance our current intravitreal gene therapy platform consisting of DNA nanoparticles/hyaluronic acid nanospheres to deliver large genes in order to develop safe and effective therapies for visual loss in Usher Syndrome Type 2A,” says Naash. “Developing an effective treatment for USH2A has been challenging due to its large coding sequence (15.8 kb) that has precluded its delivery using standard approaches and the presence of multiple isoforms with functions that are not fully understood."

BCM researcher on the impact of stress

This Baylor researcher is looking at the relationship between stress and brain cancer thanks to a new grant. Photo via Andriy Onufriyenko/Getty Images

Stress can impact the human body in a number of ways — from high blood pressure to hair loss — but one Houston scientist is looking into what happens to bodies in the long term, from age-related neurodegeneration to cancer.

Dr. Steven Boeynaems is assistant professor of molecular and human genetics at Baylor College of Medicine. His lab is located at the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, and he also is a part of the Therapeutic Innovation Center, the Center for Alzheimer’s and Neurodegenerative Diseases, and the Dan L Duncan Comprehensive Cancer Center at Baylor.

Recently, the Cancer Prevention and Research Institute of Texas, or CPRIT, awarded Boeynaems a grant to continue his work studying how cells and organisms respond to stress.

“Any cell, in nature or in our bodies, during its existence, will have to deal with some conditions that deviate from its ideal environment,” Boeynaems says in a BCM press release. “The key issue that all cells face in such conditions is that they can no longer properly fold their proteins, and that leads to the abnormal clumping of proteins into aggregates. We have seen such aggregates occur in many species and under a variety of stress-related conditions, whether it is in a plant dealing with drought or in a human patient with aging-related Alzheimer’s disease."

Now, thanks to the CPRIT funding, he says his lab will now also venture into studying the role of cellular stress in brain cancer.

“A tumor is a very stressful environment for cells, and cancer cells need to continuously adapt to this stress to survive and/or metastasize,” he says in the release.

“Moreover, the same principles of toxic protein aggregation and protection through protein droplets seem to be at play here as well,” he continues. “We have studied protein droplets not only in humans but also in stress-tolerant organisms such as plants and bacteria for years now. We propose to build and leverage on that knowledge to come up with innovative new treatments for cancer patients.”

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