3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Zain Shauk of Dream Harvest, Juliana Garaizar of Greentown Houston, and Jay Manouchehri of Fluence Analytics. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from sustainability to chemical analytics — recently making headlines in Houston innovation.

Zain Shauk, CEO of Dream Harvest

Zain Shauk, co-founder and CEO of Dream Harvest, joins the Houston Innovators Podcast just ahead of Earth Day. Photo courtesy of Dream Harvest

Zain Shauk is focused on future of farming, and the industry's success depends on making more environmentally friendly changes to the supply chain, and new technologies are enabling vertical indoor farming to effect these changes in some part. Shauk's company Dream Harvest recently received a $50 million investment from Orion Energy Partners to open a 100,000-square-foot indoor farming facility in Houston to scale production.

Shauk says he's also using the funding to support research and development to expand into other types of produce, but he has a lot to consider — affordability of the produce, maintaining sustainability, and more.

"It's going to take a lot of work and a lot of research. What I do know is we've come a long way with leafy greens," Shauk says. "When we started, we weren't growing in a way that makes financial sense with the amount of money we have to spend growing the product — and now we do." Click here to read more.

Juliana Garaizar, head of the Houston incubator and vice president of innovation

Greentown Houston's first year was surprising for Juliana Garaizar. Photo courtesy

Greentown Houston opened a year ago and, in just those 365 days, grew to over 60 member companies – something that took the original Boston-area location years. Juliana Garaizar says in a recent Q&A that this is due to companies outside of Houston looking for an entry point into the city for access to businesses, employees, and more. Specifically, she calls out Austin companies and businesses from Latin America.

"There are plenty of companies from Latin America coming over and choosing Houston as a landing pad and choosing Greentown as the place to start settling," she says. "We help them with funding. We help them with hiring local people." Click here to read more.

Jay Manouchehri, CEO of Fluence Analytics

Jay Manouchehri is now CEO of Fluence Analytics, and co-founder Alex Reed has transitioned to president and chief commercial officer. Photo courtesy of Fluence Analytics

Fluence Analytics, which moved its headquarters to the Houston area from New Orleans last year, has named Jay Manouchehri as the company's CEO. Manouchehri has worked in leadership roles within digital transformation at ABB and Honeywell all around the world, as well as in consulting and private equity.

Manouchehri tells InnovationMap he is focused on leading industrial growth.

“The next step for Fluence is really that we are industrializing our product and getting it into the industrial market," Manouchehri says. "That's exactly why we moved to Houston — it's where a lot of our clients are. We're building up and structure the company in such a manner that it could scale, get the right partnerships, and hire a team to take us to the next level and deliver the technology." Click here to read more.

Zain Shauk, co-founder and CEO of Dream Harvest, joins the Houston Innovators Podcast just ahead of Earth Day. Photo courtesy of Dream Harvest

Houston innovator: 'The climate has already changed' — here's the impact indoor farming can make

HOUSTON INNOVATORS PODCAST EPISODE 130

Modern agriculture and produce farming is not sustainable — whether you're using the environmental impact definition of that word or in terms of a lasting economy.

This concept has been made abundantly clear to Zain Shauk, co-founder and CEO of Houston-based Dream Harvest Farming Co., a vertical indoor farming company producing leafy greens and herbs and delivering them locally to grocery stores in Texas and nearby states.

"The inspiration for Dream Harvest is really the problem with our food system and agriculture today," Shauk says on this week's episode of the Houston Innovators Podcast. "Thirty-five percent of the produce grown is thrown away before you even have a chance to eat it. Almost more astounding than that is that 80 percent of our water use as a nation is agricultural."

Shauk brings up California as an example because the state's constant water shortage is hindering outdoor farming. The country relies on California for leafy greens, and both due to the lack of water and the fact that it takes produce seven to 10 days to travel from the West Coast to Texas grocery aisles, it's not an ideal process in any way. Dream Harvest can change that.

"The climate is changing now. We talk about Earth Day and the importance of realizing our impact on the planet, but we are already there," Shauk says on the show. "The climate has already changed."

The future of produce depends on making more environmentally friendly changes to the supply chain, and new technologies are enabling vertical indoor farming to effect these changes in some part. Dream Harvest recently received a $50 million investment from Orion Energy Partners to open a 100,000-square-foot indoor farming facility in Houston to scale production. Shauk says he's also using the funding to support research and development to expand into other types of produce, but he has a lot to consider — affordability of the produce, maintaining sustainability, and more.

"It's going to take a lot of work and a lot of research. What I do know is we've come a long way with leafy greens," Shauk says. "When we started, we weren't growing in a way that makes financial sense with the amount of money we have to spend growing the product — and now we do."

Some of the reasons for advances in vertical farming is new technology — which is coming out of a slightly different green industry.

"Cannabis has really driven a lot of the innovation — there's been so much money poured into the marijuana industry to grow it for commercial sale, and that's evolved a rapid development in technology for indoor growing," Shauk says, adding that one example of this is indoor lighting. "There's so much interest in making money on marijuana, that we're benefiting off that from produce."

Shauk shares more about the future of Dream Harvest and vertical farming, as well as what Houstonians can do to shrink their carbon footprint, on the podcast episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

This week's roundup of Houston innovators includes Gaurav Khandelwal of Velostics, Samantha Hepler of SeekerPitch, and Zain Shauk of Dream Harvest. Courtesy photos

3 Houston innovators to know this week

WHO'S WHO

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from logistics tech to sustainability — recently making headlines in Houston innovation.

Gaurav Khandelwal, CEO and founder of Velostics

Velostics has fresh funding to support growing its logistics software solution. Photo courtesy of Velostics

The logistics industry has a lot of room for improved optimization — and that's exactly what Gaurav Khandelwal set out to do when he founded Velostics. The company just raised its $2.5 million seed round that will go toward recruiting top talent for Velostics's team, particularly in its account management, inside sales, and marketing departments, as well as continuing to develop the AI-driven product, which has an impact for both its users and the environment.

“Idling trucks waiting outside facilities emit over 42 million tons of CO2 annually — eight times the US national average. By orchestrating the movement of trucks in and out of facilities, not only do we provide tremendous supply chain benefits, we also help the environment," Khandelwal says in the release. "We’re excited to partner with our customers and our investors to solve global congestion.” Click here to read more.

Samantha Hepler, CEO and founder of SeekerPitch

Samantha Hepler had the idea for SeekerPitch based on her own ill-fated job hunt experience. Photo courtesy of SeekerPitch

When Houstonian Samantha Hepler was trying to find a job, she couldn't even get in the door. Due to algorithms and antiquated hiring processes, she was overlooked.

"I knew if I could just get through the door, a company would see the value in me," Hepler tells InnovationMap. "I wasn't being seen, and I wasn't being heard. I didn't know a way to do that."

This experience gave her the idea for SeekerPitch, a platform that allows job seekers to create an account and tell their story — not just their job history. The platform prioritizes video content and quick interviews so that potential hires can get face-to-face with hiring managers. Click here to read more.

Zain Shauk, co-founder and CEO of Dream Harvest

Dream Harvest picked up funding to open a 100,000-square-foot indoor farming facility in Houston. Photo courtesy of Dream Harvest

Houston-based Dream Harvest Farming Co., which specializes in sustainably growing produce, has landed a $50 million investment from Orion Energy Partners to open a 100,000-square-foot indoor farming facility in Houston. The facility will enable the company to dramatically ramp up its operations.

Zain Shauk, co-founder and CEO of Dream Harvest, says his company’s method for growing lettuce, baby greens, kale, mustards, herbs, collards, and cabbage helps cut down on food waste.

“Demand for our produce has far outpaced supply, an encouraging validation of our approach as well as positive news for our planet, which is facing the rising problem of food and resource waste,” Shauk says. “While we have the yields today to support our business, we are pleased to partner with Orion on this financing, which will enable us to greatly expand our production and increase access to our produce for many more consumers.” Click here to read more.

Dream Harvest picked up funding to open a 100,000-square-foot indoor farming facility in Houston. Photo courtesy of Dream Harvest

Houston sustainability-focused company raises $50 million to plant new indoor farming facility

seeing green

Houston-based Dream Harvest Farming Co., which specializes in sustainably growing produce, has landed a $50 million investment from Orion Energy Partners to open a 100,000-square-foot indoor farming facility in Houston. The facility will enable the company to dramatically ramp up its operations.

The new facility, which will be built in Southwest Houston, is scheduled for completion in January 2023. Dream Harvest’s existing 7,500-square-foot facility in Southwest Houston supplies 45 Whole Foods stores in Texas, Oklahoma, Louisiana, and Arkansas, as well as Sweetgreen restaurants in Texas.

The company currently employs 25 people. With the addition of the 100,000-square-foot facility, Dream Harvest’s headcount will rise to 65.

Dream Harvest relies on wind-powered, year-round indoor vertical farming to generate 400 times the yield of an outdoor farm while using 95 percent less water and no pesticides.

“Because the vast majority of America’s produce is grown in California and has to be shipped over long distances, most of the country receives produce that is old, has a poor flavor profile, and a short shelf life — a major contributing factor to the more than 30 percent of fresh vegetables being discarded in the U.S. each year,” Dream Harvest says in a December 7 news release.

Zain Shauk, co-founder and CEO of Dream Harvest, says his company’s method for growing lettuce, baby greens, kale, mustards, herbs, collards, and cabbage helps cut down on food waste.

“Demand for our produce has far outpaced supply, an encouraging validation of our approach as well as positive news for our planet, which is facing the rising problem of food and resource waste,” Shauk says. “While we have the yields today to support our business, we are pleased to partner with Orion on this financing, which will enable us to greatly expand our production and increase access to our produce for many more consumers.”

Dream Harvest expects to expand distribution to more than 250 retail locations in 2022.

“Orion’s focus on sustainable infrastructure and deep experience in building large industrial facilities will be complementary to Dream Harvest’s impressive track record of being a reliable supplier to high-caliber customers by achieving consistent yields, food safety, and operational efficiencies … ,” says Nazar Massouh, co-managing partner and CEO of Orion Energy Partners, which has offices in Houston and New York City.

Other companies in the Orion Energy Partners portfolio include Houston-based Caliche Development Partners, Tomball-based Python Holdings, The Woodlands-based Evolution Well Services, Houston-based Produced Water Transfer, and Houston-based Tiger Rentals.

Zain Shauk is the co-founder and CEO of Dream Harvest. Photo courtesy of Dream Harvest

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

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