3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Zain Shauk of Dream Harvest, Juliana Garaizar of Greentown Houston, and Jay Manouchehri of Fluence Analytics. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from sustainability to chemical analytics — recently making headlines in Houston innovation.

Zain Shauk, CEO of Dream Harvest

Zain Shauk, co-founder and CEO of Dream Harvest, joins the Houston Innovators Podcast just ahead of Earth Day. Photo courtesy of Dream Harvest

Zain Shauk is focused on future of farming, and the industry's success depends on making more environmentally friendly changes to the supply chain, and new technologies are enabling vertical indoor farming to effect these changes in some part. Shauk's company Dream Harvest recently received a $50 million investment from Orion Energy Partners to open a 100,000-square-foot indoor farming facility in Houston to scale production.

Shauk says he's also using the funding to support research and development to expand into other types of produce, but he has a lot to consider — affordability of the produce, maintaining sustainability, and more.

"It's going to take a lot of work and a lot of research. What I do know is we've come a long way with leafy greens," Shauk says. "When we started, we weren't growing in a way that makes financial sense with the amount of money we have to spend growing the product — and now we do." Click here to read more.

Juliana Garaizar, head of the Houston incubator and vice president of innovation

Greentown Houston's first year was surprising for Juliana Garaizar. Photo courtesy

Greentown Houston opened a year ago and, in just those 365 days, grew to over 60 member companies – something that took the original Boston-area location years. Juliana Garaizar says in a recent Q&A that this is due to companies outside of Houston looking for an entry point into the city for access to businesses, employees, and more. Specifically, she calls out Austin companies and businesses from Latin America.

"There are plenty of companies from Latin America coming over and choosing Houston as a landing pad and choosing Greentown as the place to start settling," she says. "We help them with funding. We help them with hiring local people." Click here to read more.

Jay Manouchehri, CEO of Fluence Analytics

Jay Manouchehri is now CEO of Fluence Analytics, and co-founder Alex Reed has transitioned to president and chief commercial officer. Photo courtesy of Fluence Analytics

Fluence Analytics, which moved its headquarters to the Houston area from New Orleans last year, has named Jay Manouchehri as the company's CEO. Manouchehri has worked in leadership roles within digital transformation at ABB and Honeywell all around the world, as well as in consulting and private equity.

Manouchehri tells InnovationMap he is focused on leading industrial growth.

“The next step for Fluence is really that we are industrializing our product and getting it into the industrial market," Manouchehri says. "That's exactly why we moved to Houston — it's where a lot of our clients are. We're building up and structure the company in such a manner that it could scale, get the right partnerships, and hire a team to take us to the next level and deliver the technology." Click here to read more.

Zain Shauk, co-founder and CEO of Dream Harvest, joins the Houston Innovators Podcast just ahead of Earth Day. Photo courtesy of Dream Harvest

Houston innovator: 'The climate has already changed' — here's the impact indoor farming can make

HOUSTON INNOVATORS PODCAST EPISODE 130

Modern agriculture and produce farming is not sustainable — whether you're using the environmental impact definition of that word or in terms of a lasting economy.

This concept has been made abundantly clear to Zain Shauk, co-founder and CEO of Houston-based Dream Harvest Farming Co., a vertical indoor farming company producing leafy greens and herbs and delivering them locally to grocery stores in Texas and nearby states.

"The inspiration for Dream Harvest is really the problem with our food system and agriculture today," Shauk says on this week's episode of the Houston Innovators Podcast. "Thirty-five percent of the produce grown is thrown away before you even have a chance to eat it. Almost more astounding than that is that 80 percent of our water use as a nation is agricultural."

Shauk brings up California as an example because the state's constant water shortage is hindering outdoor farming. The country relies on California for leafy greens, and both due to the lack of water and the fact that it takes produce seven to 10 days to travel from the West Coast to Texas grocery aisles, it's not an ideal process in any way. Dream Harvest can change that.

"The climate is changing now. We talk about Earth Day and the importance of realizing our impact on the planet, but we are already there," Shauk says on the show. "The climate has already changed."

The future of produce depends on making more environmentally friendly changes to the supply chain, and new technologies are enabling vertical indoor farming to effect these changes in some part. Dream Harvest recently received a $50 million investment from Orion Energy Partners to open a 100,000-square-foot indoor farming facility in Houston to scale production. Shauk says he's also using the funding to support research and development to expand into other types of produce, but he has a lot to consider — affordability of the produce, maintaining sustainability, and more.

"It's going to take a lot of work and a lot of research. What I do know is we've come a long way with leafy greens," Shauk says. "When we started, we weren't growing in a way that makes financial sense with the amount of money we have to spend growing the product — and now we do."

Some of the reasons for advances in vertical farming is new technology — which is coming out of a slightly different green industry.

"Cannabis has really driven a lot of the innovation — there's been so much money poured into the marijuana industry to grow it for commercial sale, and that's evolved a rapid development in technology for indoor growing," Shauk says, adding that one example of this is indoor lighting. "There's so much interest in making money on marijuana, that we're benefiting off that from produce."

Shauk shares more about the future of Dream Harvest and vertical farming, as well as what Houstonians can do to shrink their carbon footprint, on the podcast episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

This week's roundup of Houston innovators includes Gaurav Khandelwal of Velostics, Samantha Hepler of SeekerPitch, and Zain Shauk of Dream Harvest. Courtesy photos

3 Houston innovators to know this week

WHO'S WHO

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from logistics tech to sustainability — recently making headlines in Houston innovation.

Gaurav Khandelwal, CEO and founder of Velostics

Velostics has fresh funding to support growing its logistics software solution. Photo courtesy of Velostics

The logistics industry has a lot of room for improved optimization — and that's exactly what Gaurav Khandelwal set out to do when he founded Velostics. The company just raised its $2.5 million seed round that will go toward recruiting top talent for Velostics's team, particularly in its account management, inside sales, and marketing departments, as well as continuing to develop the AI-driven product, which has an impact for both its users and the environment.

“Idling trucks waiting outside facilities emit over 42 million tons of CO2 annually — eight times the US national average. By orchestrating the movement of trucks in and out of facilities, not only do we provide tremendous supply chain benefits, we also help the environment," Khandelwal says in the release. "We’re excited to partner with our customers and our investors to solve global congestion.” Click here to read more.

Samantha Hepler, CEO and founder of SeekerPitch

Samantha Hepler had the idea for SeekerPitch based on her own ill-fated job hunt experience. Photo courtesy of SeekerPitch

When Houstonian Samantha Hepler was trying to find a job, she couldn't even get in the door. Due to algorithms and antiquated hiring processes, she was overlooked.

"I knew if I could just get through the door, a company would see the value in me," Hepler tells InnovationMap. "I wasn't being seen, and I wasn't being heard. I didn't know a way to do that."

This experience gave her the idea for SeekerPitch, a platform that allows job seekers to create an account and tell their story — not just their job history. The platform prioritizes video content and quick interviews so that potential hires can get face-to-face with hiring managers. Click here to read more.

Zain Shauk, co-founder and CEO of Dream Harvest

Dream Harvest picked up funding to open a 100,000-square-foot indoor farming facility in Houston. Photo courtesy of Dream Harvest

Houston-based Dream Harvest Farming Co., which specializes in sustainably growing produce, has landed a $50 million investment from Orion Energy Partners to open a 100,000-square-foot indoor farming facility in Houston. The facility will enable the company to dramatically ramp up its operations.

Zain Shauk, co-founder and CEO of Dream Harvest, says his company’s method for growing lettuce, baby greens, kale, mustards, herbs, collards, and cabbage helps cut down on food waste.

“Demand for our produce has far outpaced supply, an encouraging validation of our approach as well as positive news for our planet, which is facing the rising problem of food and resource waste,” Shauk says. “While we have the yields today to support our business, we are pleased to partner with Orion on this financing, which will enable us to greatly expand our production and increase access to our produce for many more consumers.” Click here to read more.

Dream Harvest picked up funding to open a 100,000-square-foot indoor farming facility in Houston. Photo courtesy of Dream Harvest

Houston sustainability-focused company raises $50 million to plant new indoor farming facility

seeing green

Houston-based Dream Harvest Farming Co., which specializes in sustainably growing produce, has landed a $50 million investment from Orion Energy Partners to open a 100,000-square-foot indoor farming facility in Houston. The facility will enable the company to dramatically ramp up its operations.

The new facility, which will be built in Southwest Houston, is scheduled for completion in January 2023. Dream Harvest’s existing 7,500-square-foot facility in Southwest Houston supplies 45 Whole Foods stores in Texas, Oklahoma, Louisiana, and Arkansas, as well as Sweetgreen restaurants in Texas.

The company currently employs 25 people. With the addition of the 100,000-square-foot facility, Dream Harvest’s headcount will rise to 65.

Dream Harvest relies on wind-powered, year-round indoor vertical farming to generate 400 times the yield of an outdoor farm while using 95 percent less water and no pesticides.

“Because the vast majority of America’s produce is grown in California and has to be shipped over long distances, most of the country receives produce that is old, has a poor flavor profile, and a short shelf life — a major contributing factor to the more than 30 percent of fresh vegetables being discarded in the U.S. each year,” Dream Harvest says in a December 7 news release.

Zain Shauk, co-founder and CEO of Dream Harvest, says his company’s method for growing lettuce, baby greens, kale, mustards, herbs, collards, and cabbage helps cut down on food waste.

“Demand for our produce has far outpaced supply, an encouraging validation of our approach as well as positive news for our planet, which is facing the rising problem of food and resource waste,” Shauk says. “While we have the yields today to support our business, we are pleased to partner with Orion on this financing, which will enable us to greatly expand our production and increase access to our produce for many more consumers.”

Dream Harvest expects to expand distribution to more than 250 retail locations in 2022.

“Orion’s focus on sustainable infrastructure and deep experience in building large industrial facilities will be complementary to Dream Harvest’s impressive track record of being a reliable supplier to high-caliber customers by achieving consistent yields, food safety, and operational efficiencies … ,” says Nazar Massouh, co-managing partner and CEO of Orion Energy Partners, which has offices in Houston and New York City.

Other companies in the Orion Energy Partners portfolio include Houston-based Caliche Development Partners, Tomball-based Python Holdings, The Woodlands-based Evolution Well Services, Houston-based Produced Water Transfer, and Houston-based Tiger Rentals.

Zain Shauk is the co-founder and CEO of Dream Harvest. Photo courtesy of Dream Harvest

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Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

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A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

10+ Houston innovation leaders in the spotlight at SXSW 2026

where to be

Houston's innovation scene will be well represented at South by Southwest (SXSW) this month.

The week-long, Austin-based conference and festival will spotlight some of the Bayou City's leaders in health care, energy, space and more. The event kicks off today, March 12, and runs through March 18. The SXSW Innovation Conference will feature keynotes, workshops, mentoring sessions and more throughout various venues in the city.

Here's who to see and when and where to find them:

March 12

Aileen Allen, venture partner at Mercury Fund

Mentor Session from 4-5:15 p.m. at Hilton Austin Downtown

Allen will host a mentoring session focused on funding, marketing, advertising, PR and the future of work.

March 13

Heath Butler, partner at Mercury Fund

SXSW Pitch-Smart Cities, Transportation, Manufacturing & Logistics from 2:30-3:30 p.m. at the J.W. Marriott

Butler will judge five innovative startups as they pitch their solutions to advance smart cities, enhance transportation systems, modernize manufacturing, transform logistics, and strengthen government infrastructure and civic operations.

Jonathan Cirtain, CEO and president of Axiom Space

The Clock is Ticking for Space - Replacing the ISS from 4-5 p.m. at the J.W. Marriott

Cirtain will discuss Axiom's pursuit of building the world’s first commercial space station.

March 14

Jesse Martinez, founder and CEO of LSA Global

SXSW Pitch-Intelligent Systems, Robotics, & Multisensory Technology from 10-11 a.m. at the J.W. Marriott

Martinez will judge five innovative startups as they pitch their technologies that aim to enhance the way people connect, communicate and share unique life experiences with those around them in a digital ecosystem.

Jennifer Schmitt, head of operations at Rhythm Energy

Powering Texas with Reliable Integrated High-Demand Energy from 10-11 a.m. at Marlow

Schmitt will join a panel to discuss how EirGrid, the state-owned electric power transmission operator in Ireland, is pioneering solutions as the country works toward 80 percent renewable integration by 2030.

Saki Sasagawa, director of business development for JETRO Houston

Now is Japan's Time: Leading the Future with Deep Tech from 10-11 a.m. at the J.W. Marriott

Sasagawa joins a panel that will share real-time insights from diverse perspectives on the forefront of Japan’s deep tech and IP businesses.

March 15

Bosco Lai, CEO and co-founder of Little Place Labs

SXSW Pitch Alumni: Where Are They Now? from 10-11 a.m. at the J.W. Marriott

Lai joins a panel of four former SXSW Pitch winners to share how they leveraged the platform to take their startups to the next level.

Tara Karimi, cofounder and chief science and sustainability officer at Cemvita

South by South America: The Rise of Southern Brazil Tech from 2:30-3:30. p.m. at The Line

Karimi will participate in a panel to discuss how Rio Grande do Sul, Brazil's southernmost state, is attracting elite talent and AI infrastructure and share insights on navigating the next wave of South American tech growth.

March 16

Dr. Pavitra P. Krishnamani, emergency medicine physician at The University of Texas MD Anderson Cancer Center

Viva La Revolution: How the Digital Age is Transforming Wellness from 11:30 a.m.-12:30 p.m. at Hilton Austin Downtown

Krishnamani will discuss the latest advancements and policies that can accelerate the digital age of health care, such as wearables, telehealth and artificial intelligence.

March 18

Charlie Childs, co-founder and CEO of Intero Biosystems

Spinning Out: What It Takes to Build a University Startup from 2:30-3:30 p.m. at The Line

Childs will join founders who spun their companies out of the University of Michigan to share the real story of navigating IP, early capital, team building, market validation and the “valley of death.”

Dr. James Allison, regental chair of immunology and director of The Allison Institute at The University of Texas MD Anderson Cancer Center

Dr. Padmanee Sharma, professor in the Department of Genitourinary Medical Oncology, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center

Beyond Checkpoints: Immunotherapy’s Next Act from 2:30-3:30 p.m. at the J.W. Marriott

Allison and Sharma will sit down with 21-year-old, Stage 4 cancer survivor Sharon Belvin and Time Magazine journalist Alice Park will discuss the future of immunotherapy and what challenges remain.

Last year, Houston startups Little Places Labs and Helix Earth won top prizes in their respective categories at the prestigious SXSW Pitch event, held this year from March 13-14. No Houston startups were named finalists to compete in this year's event.

NASA revamps Artemis moon landing program by modeling it after Apollo

To the moon

NASA is revamping its Artemis moon exploration program to make it more like the fast-paced Apollo program half a century ago, adding an extra practice flight before attempting a high-risk lunar landing with a crew in two years.

The overhaul in the flight lineup came just days after NASA’s new moon rocket returned to its hangar for more repairs, and a safety panel warned the space agency to scale back its overly ambitious goals for humanity’s first lunar landing since 1972.

Artemis II, a lunar fly-around by four astronauts, is off until at least April because of rocket problems.

The follow-up mission, Artemis III, had been targeting a landing near the moon’s south pole by another pair of astronauts in about three years. But with long gaps between flights and concern growing over the readiness of a lunar lander and moonwalking suits, NASA’s new administrator Jared Isaacman announced that mission would instead focus on launching a lunar lander into orbit around Earth in 2027 for docking practice by astronauts flying in an Orion capsule.

The new plan calls for a moon landing — potentially even two moon landings — by astronauts in 2028.

“Everybody agrees. This is the only way forward,” Isaacman said.

The hydrogen fuel leaks and helium flow problems that struck the Space Launch System rocket on the pad at NASA's Kennedy Space Center in February also plagued the first Artemis test flight without a crew in 2022.

Another three-year gap was looming between Artemis II and the moon landing by astronauts as originally envisioned, Isaacman said.

Isaacman stressed that “it should be incredibly obvious” that three years between flights is unacceptable. He'd like to get it down to one year or even less.

Isaacman, a tech billionaire who bought his own trips to orbit and performed the world’s first private spacewalk, took the helm at NASA in December.

During NASA’s storied Apollo program, he said, astronauts’ first flight to the moon was followed by two more missions before Neil Armstrong and Buzz Aldrin landed on the moon. What's more, he added, the Apollo moonshots followed one another in quick succession, just as the earlier Projects Mercury and Gemini had rapid flight rates, sometimes coming just a few months apart.

Twenty-four Apollo astronauts flew to the moon from 1968 through 1972, with 12 of them landing.

“No one at NASA forgot their history books. They knew how to do this," Isaacman said. “Now we're putting it in action.”

To pick up the pace and reduce risk, NASA will standardize its Space Launch System rockets moving forward, Isaacman said. These are the massive rockets that will launch astronauts to the moon aboard Orion capsules. At the same time, Elon Musk's SpaceX and Jeff Bezos' Blue Origin are speeding up their work on the landers needed to get the astronauts from lunar orbit down to the surface.

Isaacman said next year will see an Orion crew rendezvousing in orbit around Earth with SpaceX's Starship, Blue Origin's Blue Moon or both landers. It's similar to the methodical approach that worked so well during Apollo in the late 1960s, he noted. Apollo 8, astronauts' first flight to the moon, was followed by two more missions before Armstrong and Aldrin aimed for the lunar surface.

“We should be getting back to basics and doing what we know works,” he said.

The Aerospace Safety Advisory Panel recommended that NASA revise its objectives for Artemis III “given the demanding mission goals.” It’s urgent the space agency do that, the panel said, if the United States hopes to safely return astronauts to the moon. Isaacman said the revised Artemis flight plan addresses the panel's concerns and is supported by industry and the Trump administration.

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