Houston med-aesthetic company acquired in $550M deal

M&A

Houston-based Soliton, which has created a technology that uses sound to treat cellulite and scars, has been acquired. Photo via soliton.com

A California company has acquired Houston-based Soliton as well as its innovative device that uses sound to eliminate cellulite.

Allergan Aesthetics, an AbbVie company, has announced an agreement to acquire Soliton and its rapid acoustic pulse device RESONICTM, which recently received U.S. Food and Drug Administration clearance for the treatment of cellulite.

The company's team first developed the basis of the tool for tattoo removal and earned FDA clearance for that treatment a few years ago. Christopher Capelli and Walter Klemp co-founded Soliton in 2012.

The acquisition will take Soliton's technology to the next level, says Klemp, who serves as the company's executive chairman.

"Allergan Aesthetics' brand recognition, global footprint, track record and commitment to developing best-in-class aesthetic treatments makes the Company ideally suited to maximize the commercial potential of the RESONICTM rapid acoustic pulse technology," Klemp says in the release.

"I am proud of the passion and accomplishments of the Soliton team and thankful for the ongoing support of our investors which have culminated in this transaction," he continues. "We look forward to working with Allergan Aesthetics to ensure a successful completion of this transaction."

For Carrie Strom, president of Global Allergan Aesthetics and senior vice president at AbbVie, Soliton's solution has a great potential in the market. Soliton's clinical trial data that was submitted to the FDA showed that after a single treatment session, RESONICTM demonstrated significant improvement and strong patient satisfaction with 92.9 percent of subjects agreeing or strongly agreeing their cellulite appeared improved, per the release.

"There is a huge unmet need to address cellulite and effective treatments have been elusive and frustrating for consumers," Strom says in the release. "Soliton's technology offers a new, completely non-invasive approach with clinically-proven results to reduce the appearance of cellulite with no patient downtime.

"The addition of this technology complements Allergan Aesthetics' portfolio of body contouring treatments," she continues. "Health care providers will now have another option to address consumers' aesthetic concerns."

Brad Hauser, CEO of Soliton, previously told InnovationMap that the company's plans for 2021 included focusing on the commercialization of their product and get it into the hands of dermatologists, plastic surgeons, and other medical professionals for 25 key accounts — potentially including ones Houston — with a plan for a national rollout in 2022.

Houston-based Moleculin Biotech now has four different oncology treatment currently in trials. Getty Images

Houston cancer-fighting biotech company introduces its 4th ongoing clinical trial

health report

A Houston-based biotech company has wrapped up enrollment for its most recent clinical trial of its cancer-fighting drug.

Moleculin Biotech Inc. (Nasdaq: MBRX) has launched its fourth ongoing trial — this time focusing on Cutaneous T-Cell Lymphoma, or CTCL, treatment. The company's other three trials include treatment for glioblastoma, an aggressive brain cancer, pancreatic cancer, one of the most virulent killers in oncology, and acute myeloid leukemia, or AML.

To treat these various types of cancers, Moleculin has a several drugs it's in preclinical or clinical trials testing — most biotech companies have only one they focus on. WP1220 is the drug that will be used in this trial for topical CTCL treatment of the cancer's resulting skin lesions.

"We believe there continues to be an unmet need for an improved topical therapy for Stage I-III CTCL skin lesions," says Walter Klemp, Moleculin's chairman and CEO, in a news release, "especially one that may avoid significant unwanted side effects."

WP1220 is what's known as a p-STAT3 inhibitor. STAT3 is a transcription factor that encourages tumor development. Moleculin's technology directly attacks the tumor, but also quiets T Cells, which allows the body's own immune system to fight the cancer itself. Essentially, it works both as chemotherapy and immunotherapy.

"This proof of concept, if successful, could be an important first demonstration of a therapeutic effect in humans from such a p-STAT3 inhibitor," Klemp continues. "We are pleased with how quickly this trial reached full recruitment and we are hopeful to be able to announce results from this trial yet this year."

Klemp founded the company in 2007, and Moleculin went public in 2016. Now, with the company's four clinical trials, Moleculin is even closer to saving lives with its products.

"Notwithstanding the relatively rare nature of CTCL, we believe showing activity with one of our STAT3 inhibitors, within our WP1066 family of molecules, could be an indicator of both the value of p-STAT3 as a target and the potential for our drugs in other cancers where STAT3 is highly activated," Klemp says in the release.

From cryotherapy and NASA-inspired fitness to startup funding and biotech, this week's innovators to know are raising the bar on health tech and innovation. Courtesy photos

4 health-focused Houston innovators to know this week

Who's who

This week's innovators to know are focused on health and wellness, from a Houston-based cryotherapy franchise to the person behind funding medical device and digital health startups. We couldn't narrow these folks down to the usual three, so here are the four Houston innovators to know as we start the last week in February.

Juliana Garaizar, director of the Texas Medical Center Venture Fund

Courtesy of TMC

Juliana Garaizar has worked all around the world, and her international contacts and venture capital experience has landed her at the heart of the Texas Medical Center leading the TMC Venture Fund.

"I think TMC wants to be positioned as a strong competitor to the East and West Coasts as a point of entry for companies coming to the United States, but also for technology and commercializations from hospitals," she tells InnovationMap. "The fact that I'm already very connected to other countries — not only from the funding side but also from the research side, is really helpful."

Garaizar has her hands full running the $25 million nonprofit fund that invests around $2 million a year. Recipients, which all have a connection to TMC either through the accelerator or workspaces, receive a range between $250,000 to $500,000, and can go up to $1 million in a deal, Garaizar says. She is focused on securing deal flow for the fund before growing it more.

"In the long term, we would like to raise a bigger fun, around $100 million fund," she says. "We would need to make sure we have our deal flow ready for that, and a big part of that would be international deal flow."

Walter Klemp, chairman and CEO of Moleculin

Courtesy of Moleculin

It's pretty concerning to Walter Klemp that, while Houston has the world's largest medical center, "the tragic irony" is that other cities have far more biotech money ready to be invested.

"The Third Coast is really starved for capital," he tells InnovationMap. "What drew me into this was I was one of the few entrepreneurs that lived here that knew the ropes in terms of tapping into East and West Coast capital structures and could make that connection for them."

In 2007, chairman and CEO Walter Klemp founded Moleculin Biotech Inc. as a private company. The company has three core technologies currently being tested with some success, but the most promising is called WP1066, which uses propolis, a compound of beeswax, sap and saliva that bees produce to seal small areas of their hives, as a base. The active compound both downregulates the STAT3, a long-time Holy Grail in the cancer research world, and directly attacking the tumor, but also quieting T Cells, which allows the body's own immune system to fight the cancer itself. Essentially, it works both as chemotherapy and immunotherapy.

Jay Sutaria, founder and lead trainer of Sutaria Training & Fitness

Courtesy of ST&F

Earthbound Houstonians have a chance to use NASA training equipment thanks to Jay Sutaria's company, Sutaria Training & Fitness.

"It's exclusive access to the equipment that is not available openly in Houston," Sutaria tells InnovationMap. "NASA is a reference for us to become better trainers."

Sutaria founded his company in 2011 while he was a student at the University of Houston, and the company now operates with two trainers. His clients include professional athletes such as D.J. Augustin (Orlando Magic, NBA); and Tim Frazier (New Orleans Pelicans, NBA), however, Sutaria and his team offer professional personal training services to any type of athlete.

Kyle Jones, COO of iCRYO

Courtesy of iCryo

Kyle Jones says he's always known he was destined for entrepreneurship, and when he came across the potential of cryotherapy while working at a physical therapist office, he knew it was a scalable business.

He opened his first location of iCRYO in League City in 2015. Now the company is

Jones says he used the location to work out the kinks of his business model, since he didn't really have much to model after. One thing that was most important to Jones, with his PT background, was safety of the patients. He cared about this more than making money, he says.

"I knew first and foremost the one thing that the cryotherapy space didn't have was a certification program, which is kind of terrifying to me," Jones tells InnovationMap. "Any therapy has some type of schooling or certification — massage therapy and acupuncture both have it. Cryotherapy even to date does not a certification to it."

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Accenture, Goodwill-backed cleantech job accelerator celebrates Houston launch

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A major nonprofit and a worldwide corporate leader have teamed up to advance cleantech jobs — and the program has officially celebrated its launch in Houston.

Goodwill Houston, in collaboration with Accenture, BlocPower, and Goodwill Industries International hosted a celebration for the Clean Tech Accelerator, an industry-focused full-time free jobs training program that was originally announced last year. The first cohort graduated earlier this year, and the second is ongoing.

"Through the CTA, we want to shape the future of sustainable energy in Houston by recruiting underrepresented jobseekers and equipping them with technical proficiency, safety and clean tech certifications, and facilitating placement with local employers," a representative from Accenture states in an email. "Following a quiet initial launch, this event was the official kickoff."

The event also demonstrated the opportunities within the CTA program for job seekers to prepare for the most in-demand clean energy careers in Houston. The accelerator is targeting a specific set of advanced energy jobs — the 40 percent that don't require college degrees and and pay more than the median salary in the United States.

According to Accenture and Goodwill, the plan is to grow the program to 20 cities in the next seven years and train an estimated 7,000 job seekers. The program, which was co-designed by Accenture, will be run by Goodwill. Participants identified as under and unemployed individuals and accepted into the program will be compensated as they undergo the training and career placement services.

"As our labor market transitions, we see important opportunities for people to move into more promising roles with better pay. It is essential that we provide the training and other support needed to ensure people capture these opportunities," Steve Preston, president and CEO of Goodwill Industries International, says in a news release announcing the program. "The Goodwill Clean Tech Accelerator will open doors for people in an expanding industry and provide support to employers who are helping us transition to a more sustainable world."

Speakers included leaders from the participating organizations. Photo courtesy of Accenture

Houston tech company building a next-generation space station has new investor

interstellar lab

Houston-based Starlab Space, which is developing a commercial space station, has enlisted a high-profile investor — Japanese industrial conglomerate Mitsubishi.

With the addition of Mitsubishi, Starlab now boasts three equity partners. The two others are aerospace company Voyager Space and defense and space product manufacturer Airbus Defense and Space. Financial terms of the Mitsubishi deal weren’t disclosed.

Voyager and Airbus finalized creation of the Starlab joint venture in January 2024. The two companies announced the joint venture in August 2023.

Dylan Taylor, chairman and CEO of Voyager, says the Mitsubishi partnership will help “unlock space technology on a global scale and drive meaningful impact across several industries, from space to ground.”

“We are very pleased to welcome Mitsubishi … as a strategic partner in our joint venture with Voyager Space. This brings Starlab Space to the next level on the way to a truly global endeavor,” Mike Schoellhorn, CEO of Airbus Defense and Space, says in a news release.

The continuously staffed, low-Earth-orbit Starlab space station will serve NASA, other space agencies, businesses, and research organizations.

Starlab announced in January 2024 that it had tapped Elon Musk’s SpaceX Starship to launch Starlab’s stainless-steel space station. A launch date hasn’t been revealed, although it’s tentatively set for the late 2020s.

The Starlab station will help fill the gap that’ll be left by the International Space Station, which NASA plans to retire in 2031.

Houston energy innovation leader calls for collaboration to tackle the industry's biggest hurdles

Houston Innovators Podcast Episode 231

When Barbara Burger moved to Houston a little over a decade ago to lead Chevron Technology Ventures, she wondered why the corporate venture group didn't have much representation from the so-called energy capital of the world.

“I had no companies in my portfolio in CTV from Houston, and I wondered why,” Burger says on the Houston Innovators Podcast.

Much has changed in the ecosystem since then, she says, including growth and development to what the community looks like now.

“There are a few things I’m proud of in the ecosystem here, and one of theme is that it’s a very inclusive ecosystem,” she explains, adding that she means the types of founders — from universities or corporate roles — and the incumbent energy companies. “The worst way to get people to not join a party is to not invite them.”

“No one company or organization is going to solve this. We have to get along,” she continues. “We have to stop thinking that the mode is to compete with each other because the pie is so big and the opportunity is so big to work together — and by and large I do see that happening.”

Burger, who has since graduated from Chevron to act as an adviser, mentor, and philanthropist across her passions, also shares her insider perspective on CERAWeek by S&P Global — from the key topics discussed to who was there this year and, notably, who wasn't. One thing that stood out to here was the practicality problems that were on the agenda.

“We need an energy system that focuses on climate, the economy, security — a lot of this is just the block and tackling of engineering, policy, economics, and community engagement. I think it was a practical discussion,” she says.

Another huge topic was the amount of energy needed in the near future.

“Everybody has woken up and realized that our load growth — our demand — is growing, and because of all kinds of things pointing toward electrification. I think that the big one in the room was AI and the power demands for it,” she says.

In addition to finding the funding to grow these new technologies, scale is extremely important when it comes to making an impact on the energy transition.

“It’s not just about the innovation — it’s really about scaling that innovation and that execution, because that’s when we get impact, when these technologies are actually used in the energy system, and when we create new businesses,” she explains on the show. “It’s going to take investment, capabilities, a real understanding of the marketplace, and, in many cases, it’s going to take a relationship with the government.”

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