Optellum, based in the TMC Innovation Institute, has entered into a partnership with Johnson & Johnson. Photo via Getty Images

Optellum, a startup whose technology helps doctors detect and treat lung cancer, has teamed up with one of the world's health care giants to broaden the software's reach.

On August 18, Optellum — whose U.S. headquarters is at Houston's TMC Innovation Institute — unveiled its new collaboration with the Lung Care Initiative at Johnson & Johnson, which racked up global sales of $82.6 billion last year. Optellum's key contribution to the partnership is its AI-powered software that aids medical professionals in detecting and treating patients with lung cancer.

With Optellum's AI-powered lung cancer diagnostics now being included in J&J's Lung Cancer Initiative, medical teams soon will enjoy access to an array of complementary technologies designed to improve diagnosis and treatment of early stage cancer. The Lung Cancer Initiative, launched in 2018 by J&J and Boston University, aims to prevent, detect, and cure lung cancer.

Lung cancer ranks as the world's most common type of cancer and leading cause of cancer deaths. About 1.8 million people around the world die from lung cancer each year. The current five-year survival rate is just 20 percent, primarily due to most patients being diagnosed after the disease has reached an advanced stage.

Optellum's Virtual Nodule Clinic software received clearance from the U.S. Food and Drug Administration (FDA) in March. Hospitals in the U.S. are rolling out the technology, with Asia-Pacific and European hospitals on track to eventually adopt the software.

The Optellum platform identifies and tracks at-risk patients, and assigns a "lung cancer prediction" score to lung nodules — small lesions, frequently detected in chest CT scans, that may or may not be cancerous.

"Optellum's vision is to redefine the early intervention of lung cancer by enabling every patient to be diagnosed and treated at the earliest possible stage, when the chances of cure are highest," the United Kingdom-based company says in a news release.

The startup — a 2019 graduate of the Texas Medical Center's accelerator — hopes to apply the technology to other lung diseases, such as chronic obstructive pulmonary disease (COPD).

Optellum recently was named one of the 101 best medical device startups in the United Kingdom. In June, the startup was among 38 AI projects chosen by the UK Department of Health and Social Care to participate in a roughly $50 million health care initiative.

Václav Potěšil, founder and CEO of Optellum, says the Johnson & Johnson collaboration represents a "significant milestone" for his company.

The J&J partnership "brings us one step closer to Optellum's vision of redefining early lung cancer treatment by helping every clinician in every hospital to make the right decisions and provide their patients the best chance to fight back," Potěšil says.

Of the 35 people employed by Optellum, three are based in the U.S. and the rest in the United Kingdom. The company's team also includes several part-time consultants, most of whom are based in the U.S. By the end of this year, Optellum plans to expand its U.S. team with several full-time hires, including a senior executive located in Houston.

Beginning next year in Houston, Optellum expects its technology to be available for patients in clinical settings.

For Potěšil, Optellum's mission is personal. He lost an aunt to lung cancer within a year of her Stage 4 diagnosis.

"I've seen firsthand how very healthy people can be killed, and it's still the most common and deadliest cancer worldwide," Potěšil is quoted as saying by the Texas Medical Center. "We are really focused on enabling cancer patients to be diagnosed at the earliest possible stage and be cured. It's not just the modeled data on the computer. It's addressing the right clinical problems to add value to doctors."

At TMCx's Demo Day, the cohort's companies boasted of local deals and accomplishments. Courtesy of TMC

TMCx companies plant Houston roots with pilots, partnerships, and more

Lasting impact

At the conclusion of TMCx's recent Digital Health cohort — the most international group to date — there was only one Houston company among the 19. However, most of that group have developed a presence in Houston throughout the program.

Besides just being based here in Houston for four months, TMCx associate director, Lance Black, says the city has a lot to offer these startups.

"Why Houston? Why are these companies coming from everywhere to be here? Three big reasons," he says to the crowd at Demo Day. "The size and scale of the Texas Medical Center, the diversity of Houston, and the willingness and hunger of Houstonians wanting to be involved in innovation."

From pilots and partnerships to funding and mentorship, these TMCx08 companies announced the impact they've made on Houston at the Demo Day on Thursday, June 6. Meanwhile, TMCx had its own announcement that it would create early stage programming for professionals connected to the Texas Medical Center.

"It is the TMC's mission to advance health care, research, and education. It's our mission at the Innovation Institute to bring value back to the med center through health care technology," Black says. "And, through TMCx, we do that through startup companies."

Here are some examples of TMCx companies setting foundations in the Houston ecosystem.

Virti

Photo via virti.com

California-based Virti has developed an extended reality simulation technology for training medical staff. It's a cheaper, more effective way to train personnel, says Alex Young, CEO of the company.

Virti was selected to be in England's National Health Service accelerator — the only evidence-based AR/VR training company ever to be picked for the program, says Young.

With a presence in California and England, Young says he's also planted roots in Texas too, with sales representation based in the TMCx offices.

"In the time that we've been here, we've closed deals in Texas and back in California," Young adds.

Optellum

Photo via optellum.com

Optellum is changing the way lung cancer is being detected. With the startup's artificial intelligence-enabled detection software, oncologists can better identify at-risk patients, which translates into more treatment for those in need, and less for those who don't.

The company, which is based in the United Kingdom, has raised funds abroad while networking locally.

"TMCx has been amazing for a small British company like us. We have started pilots and trials at four TMC member institutions," says Vaclav Potesil, CEO.

Oncora Medical

Photo via oncoramedical.com

Angela Holmes, the director of product and customer solutions of Oncora Medical, sets the stage at her company's Demo Day pitch by telling a story of her friend's daughter who was diagnosed with cancer. She was forced to pick between two treatment options. She had no data or insights to help.

Oncora Medical's mission is to help fight cancer using data. Though based in Philadelphia, Oncora has Houston ties, since it formed a partnership with MD Anderson Cancer Center in April of 2017.

"We are so honored and gratified to be in a strategic, multi-year collaboration with MD Anderson to build this software system to save the world," Holmes says.

PreOp MD

Cody Duty/TMC

Within health care, the projected annual aggregate surgical expenditure by 2025 is expected to be $912 billion, says Christiana Obi, founder and CEO of PreOp MD, and a Houston-based anesthesiologist. She sees lack of information causing wasted surgical resources regularly.

PreOp MD — the only Houston-based TMCx company this cohort — has an app that allows for pre-procedure education, communication, and more that aims to prevent surgical delays.

While based here, PreOp is truly rooted in Houston, and even more so with their latest news.

"We are happy and excited to say that we have landed our first medical pilot at an medical right here in town," Obi says.

RoundTrip

Cody Duty/TMC

RoundTrip has a solution to 3.6 million missed or postponed medical visits that happen annually that are inconvenient to hospitals and a major health risk to the population: Ride sharing.

The Philadelphia-based company enables all forms of transportation and puts the power in the hands of the medical institution. From ambulances to other medical vehicles, the company can optimize utilization of all vehicles to get patients to their appointments and even has a partnership with Lyft.

While completing the TMCx program, RoundTrip closed its Series A round of $5.14 million led by Virginia-based Motley Fool Ventures in April. The funds will be used for expansion.

"Now we have all this new money to expand really rapidly. Texas, we're coming for you, whether you're ready or not," says Jackson Steeger, account supervisor.

Meru Health

Photos via meruhealth.com

Meru Health is also one of the 2019 TMCx Digital Health companies that has raised money while in the program. Palo Alto, California-based Meru completed a $4.2M raise in April 2019. The round was led by San Francisco-based Freestyle Capital.

Access to mental health professionals is increasingly more difficult, so Meru Health has created a low-cost digital clinic that offers an app-based treatment program from licensed therapists. Kristian Ranta, CEO and founder, while not yet providing specifics, that they aren't done in Texas.

"I'm happy to say there's some good stuff brewing here in Texas for us. More to follow," says Ranta.

Cloud 9

Photo via cloud9psych.com

Mental health is a key contributing factor in the legal system cycle, but it doesn't have to be Liz Truong, co-founder of Cloud 9. Better educating officers and providing them with mental health resources is the best way to get them out of the hospitals and court rooms and back out in the field to protect the city.

While some police departments have instituted ride-along programs with mental health professionals that have showed success, it's expensive for the police department and risky for those professionals. Cloud 9 has created a digital solution.

"We proved this works in the Harris County Sheriff's office right here in Houston," says Truong. "Officers reported that 97 percent of Cloud 9 care was superior or equal to their current program and showed an immediate 632 percent return on investment for our customers in the same budget cycle compared to what they were already spending."

Truong also says they have other local customers they are working with, including the Harris County Health Department.

Axem Neurotechnology

Photos via axemneuro.com

Recovering stroke patients need rehabilitation to get back to 100 percent, but getting patients into the facility is challenging and at-home compliance is hard to track.

Canadian company Axem Neurotechnology has a solution. With their external device and mobile application, physical therapists can track progress and communicate with patients remotely.

"When we talk to rehab professionals, they are excited about what we're doing," says Tony Ingram, CEO and co-founder. "That's why we have leading institutions in both Canada and the U.S. onboard for clinical trials — this includes TMC's own TIRR, which is consistently ranked in the top five rehab centers in the U.S. We're collecting core baseline data in the most diverse city in the country."


Correction: A previous version of this article said Oncora's partnership with MD Anderson was formed during the TMCx program, when the partnership began in 2017.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

10+ can't-miss Houston business and innovation events for June

Where to be

It's time to look at what's on the agenda for June for Houston innovators — from pitch competitions to networking events.

Here's a roundup of events not to miss this month. Mark your calendars and register accordingly.

Note: This post might be updated to add more events.


June 2 — Boost Your Brand's Online Visibility with a Book

Discover the untapped potential of self-publishing a book to establish your expertise, increase your visibility, and build your network. If you have ever considered publishing a book someday, this event is for you.

The event is Friday, June 2, from 8:30 to 10:30 am, at Impact HUB (Amegy Building - 1801 Main St 10th floor.) Click here to register.

June 2 — Best AI Tools for Business Innovation and Growth

This informative workshop is aimed at introducing participants to the latest AI tools available for businesses to innovate and grow. The interactive sessions will provide practical insights and expert advice from speakers who are experts in the field of AI. Participants will learn about the various AI tools that can be used for businesses, including machine learning, natural language processing, computer vision, and more.

The event is Friday, June 2, from 10 to 11 am, online. Click here to register.

June 7-9 — The Future of Global Energy Conference

To highlight Houston's role in the global energy transition, the Greater Houston Partnership, Houston Energy Transition Initiative, and Center for Houston's Future will host a dynamic three-day conference focusing on the role community engagement, innovation and technology, workforce, and funding play in implementing Houston's energy transition strategy.

The event is Wednesday, June 7, to Friday, June 9. The event is hybrid at various locations in Houston. Click here to register.

June 8 — Out in Tech Houston | Monthly Mixer

Out in Tech provides an inclusive networking space for LGBTQ+ people and allies working in tech. Join this relaxed, social-mixer event, hosted on the second Thursday of every month.

The event is Thursday, June 8, at 6:30 to 8:30 pm at Avant Garden. Click here to register.

June 9 — The Future of Global Energy Conference: Luncheon

The Future of Global Energy conference concludes with a gathering of experts and thought leaders, exploring the roadmap for Houston to lead the transition to an energy-abundant, low-carbon future. Panelists include:

  • Jim Gable, President, Chevron Technology Ventures
  • John Hall, President & CEO, Houston Advanced Research Center (HARC)
  • Dr. Ramanan Krishnamoorti, Chief Energy Officer, University of Houston
  • MODERATOR: Jane Stricker, Senior Vice President, Energy Transition & Executive Director, Houston Energy Transition Initiative, Greater Houston Partnership

The event is Friday, June 9, from 10 am to 3 pm, at Hilton Americas. Click here to register.

June 9-10 — Mission Innovate - Reimagining Space Technology to Solve Today’s Challenges

This summer, innovators from around the greater Houston area will convene for a two-day event to innovate, disrupt, and help design innovative solutions that can address gaps in numerous key areas. Entrepreneurs will work with licensable intellectual property from NASA’s IP portfolio to solve some of the largest problems facing the industry. Experienced and first-time founders will form teams, ideate, and pitch their ideas to renown technology entrepreneurs, including members of the innovation teams at NASA. As part of the event, teams will be taught critical startup methodologies, advised by experienced business leaders, and network with an entire community that dreams of shaping key areas in emerging technology.

The event is Thursday, June 9, to Friday, June 10, at the Cannon West Houston. Click here to register.

June 12-14 — Energy Drone & Robotics Summit

The most influential gathering of over 1,500 industrial, energy, and engineering leaders from around the globe where the key challenges and solutions are addressed for operating robotics, drones, satellites, and remote systems successfully and managing AI/data, from the stars to the sea floor.

The event is Monday, June 12, to Wednesday, June 14, at Woodlands Waterway Marriott & Convention Center. Click here to register.

June 13 — Investor Studio Series: VC Due Diligence Best Practices

During this event, Golden Section, a venture capital fund and founders studio obsessed with B2B SaaS product development, will discuss how VCs approach investing and conduct due diligence, and why this matters for founders. The presentation will cover:

  • Market changes that effect how VCs approach investing
  • What founders need to prepare for this new environment
  • How Golden Section approaches due diligence

The event is Tuesday, June 13, from 4 to 6 pm, at the Ion. Click here to register.

June 13 — Using ChatGPT to Grow Your Business

Learn how to harness the power of artificial intelligence and use ChatGPT to not only stay ahead of the game but to redefine it. Whether it's handling queries, managing customer relationships, or generating leads, AI can automate and enhance many aspects of your work. This session will guide attendees through the fascinating world of AI and show them how to leverage it for maximum results.

The event is Tuesday, June 13, from 11 am to 1 pm, at Amcap Mortgage. Click here to register.

June 15 — Female Founders and Funders Meetup

Monthly, every third Thursday, Softeq Venture Studio and Sesh Coworking invite all rockstar female founders and funders in the Houston area to network and empower each other.

The event is Thursday, June 15, from 9 to 10 am, at Sesh Coworking. Click here to register.

June 20 — Co-Creating the Future: An African Startup Symposium on Collaboration

This physical symposium explores opportunities for cross-border entrepreneurial collaboration between the US/Houston and Africa. From Idea to Impact, delving into the African startup ecosystem, highlighting growth and potential for cross-border collaboration, key sectors driving innovation and growth, and legal, regulatory, and cultural considerations and challenges for cross-border collaborations. Startups and investment opportunities will be showcased.

The Agenda:

6:00 pm - 6:10 pm - Introduction to the event and The Beta Collective
6:15 pm - 6:20 pm - Sponsors Highlight
6:20 pm - 6:35 pm - Startup showcase
6:35 pm - 6:40 pm - Panel Introduction
6:40 pm- 7:30 pm - Panel
7:30 - 7:50 pm - Q&A
7:50 - 8:00 pm- Closing and Thanks
8:00 - 8:30 pm - Strategic Networking

The event is Tuesday, June 20, from 6 to 8:30 pm, at The Ion. Click to register.

June 22 — Ultrasound. Integrated. Everywhere.

Pump & Pipes is hosting an event focused on thin-film ultrasound technologies from energy applications into aerospace, health, and medtech sectors.

In collaboration with NASA Tech Talks, and the Mingle Monday Health & MedTech series at The Ion, join Pumps & Pipes as they venture into a discussion on the use of ultrasound technologies from both terrestrial and space medicine perspectives.

The event is Thursday, June 22, from 6 to 9 pm, at the Ion. Click here to register.

June 28 — June Transition On Tap

Transition On Tap is Greentown Labs' monthly networking event devoted to fostering conversations and connections among the climate and energy transition ecosystem in Houston and beyond. Entrepreneurs, investors, students, and friends of climatetech are invited to attend, meet colleagues, discuss solutions, and engage with our growing community. If you’re looking for a job in climatetech or energy, trying to expand your network, or perhaps thinking about starting your own energy-related company, this is the event for you.

The event is Wednesday, June 28, from 5:30 to 7:30 pm, at the Ion. Click here to register.

Texans take note — council warns of summer energy shortfalls

heating up

The North American Electric Reliability Council issued a statement in its 2023 Summer Reliability Assessment earlier this month warning that energy shortages could be coming this summer for two-thirds of North America if temperatures spike higher than normal.

“Increased, rapid deployment of wind, solar and batteries have made a positive impact,” Mark Olson, NERC’s manager of reliability assessments, says in a news release. “However, generator retirements continue to increase the risks associated with extreme summer temperatures, which factors into potential supply shortages in the western two-thirds of North America if summer temperatures spike.”

For Texans, the combined risk of drought and higher than normal temperatures could stress ERCOT system resources, especially in a case of reduced wind. But before there’s a mad rush on generators, keep in mind, electricity consumers can take simple actions to minimize the possibility of widespread shortfalls.

Electricity demand begins rising daily around 2 pm in the summer and peaks in the final hours of daylight. These hours are generally not only the warmest hours of the day, but also the busiest. People return from work to their homes, crank down the air conditioner, turn on TVs, run a load of wash, and prepare meals using multiple electric-powered appliances.

In light of NERC's findings, Americans are recommended to take s one or two small steps to avoid unnecessary stress on the grid in the hours after coming home from work, we can prevent energy shortfalls. Modify routines now to get into the habit of running the dishwasher overnight, using the washer and dryer before noon or after 8 pm and pulling the shades down in the bright afternoon hours of the day. Delaying powering up devices – including EVs – until after dark and turning off and unplug items to avoid sapping electricity when items are not in use is also recommended, in addition to turning up thermostats a couple of degrees.

Meet the innovator who's leveraging big tech to advance Houston's ecosystem equitably

HOUSTON INNOVATORS PODCAST EPISODE 188

At a glance, Rob Schapiro's resume might not make the most sense. A trained geologist with decades of experience in the energy sector, Schapiro made the move to Microsoft three years ago.

"I saw this disconnect between technology companies and energy companies — they didn't really speak the same language," he says on this week's episode of the Houston Innovators Podcast. "I thought I could help potentially solve this problem and work between the two as a sort of translator."

Now, as Microsoft’s Energy Acceleration Program director and site leader for the company’s Houston office, which is located in the Ion, Schapiro is deeply embedded in Houston's innovation ecosystem and is dedicated to helping advance Houston's role energy transition in a sustainable and equitable way.

Inspired by the murder of George Floyd, Schapiro says he sought out opportunities in his personal life to expand his contribution to the community as an ally, and he became a big brother in Big Brothers Big Sisters. Microsoft, too, is active in supporting the community through partnering with local organizations, including SUPERGirls SHINE Foundation, the G-Unity Foundation Inc., and more.

"This has been one of the most rewarding aspects of my job, that I've had the ability to leverage the might of Microsoft and my own privilege to have an impact on real people," Schapiro says. "Microsoft's mission is to empower every person and every organization on the planet to achieve more, and when you think about how you do that, it's really daunting. We realized that in order to do that, it's going to require a workforce that looks really different than it does today."

Microsoft knows too well the changing workforce, both from a diversity perspective and when it comes to artificial intelligence and other new technology. In its recent Work Trend Index report, the company found that, rather than being afraid of AI replacing jobs, the majority of the workforce is interested in applying AI to mundane tasks.

Schapiro shares more about his view of how AI will affect the workforce, plus what all the energy industry needs to focus on amid the energy transition, on the podcast. He also weighs in on how Houston's innovation ecosystem has evolved and where he hopes it's going. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.