Houston's top innovators and startups for 2025 and more news to know

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The reveal of the 2025 Houston Innovation Awards finalists is a top story this month. Photo via marsmaterials.tech

Editor's note: We're looking back at the top Houston innovation news for the first half of October 2025, including the big reveal of our 2025 Houston Innovation Awards finalists. Here are the five most-read InnovationMap stories from Oct. 1-15, 2025:

1. Announcing the 2025 Houston Innovation Awards finalists

Meet the finalists for the Houston Innovation Awards, taking place Nov. 13. Graphic via Gow Media

InnovationMap is proud to reveal the finalists for the 2025 Houston Innovation Awards. Taking place on November 13 at Greentown Labs, the fifth annual Houston Innovation Awards will honor the best of Houston's innovation ecosystem, including startups, entrepreneurs, mentors, and more. This year's finalists were determined by our esteemed panel of judges, comprised of past award winners and InnovationMap editorial leadership. Continue reading.

2. 5 minority-founded Houston startups shine as Innovation Awards finalists

These five minority-founded businesses stood out to the judges for the 2025 Houston Innovation Awards. Photo via marsmaterials.tech

Houston is one of the most diverse cities in the nation, and that trend carries over into its innovation and startup ecosystem. As part of the 2025 Houston Innovation Awards, our Minority-founded Businesses category will honor an innovative Houston startup founded or co-founded by BIPOC or LGBTQ+ representation. Five minority-founded businesses have been named finalists for the 2025 award. The finalists range from a wearable health tech device company to a clean chemical manufacturing business to a startup with a lunar mission. Continue reading.

3. 2 UH projects named finalists for $50M fund to shape future of Gulf Coast

One project involves the innovative recycling of wind turbines into seawall and coastal habitats. Courtesy rendering

Two University of Houston science projects have been selected as finalists for the Gulf Futures Challenge, which will award a total of $50 million to develop ideas that help benefit the Gulf Coast. Sponsored by the National Academies of Science, Engineering and Medicine’s Gulf Coast Research Program and Lever for Change, the competition is designed to spark innovation around problems in the Gulf Coast, such as rising sea levels, pollution, energy security, and community resiliency. The two UH projects beat out 162 entries from organizations based in Alabama, Florida, Louisiana, Mississippi, and Texas. Continue reading.

4. 3 Houston-area companies appear on Fortune’s inaugural AI ranking

Spring-based ExxonMobil ranks within the top 10 on the new Fortune AIQ 50 ranking. Photo via Getty Images.

Three companies based in the Houston area appear on Fortune’s inaugural list of the top adopters of AI among Fortune 500 companies. The Fortune AIQ 50 ranking is based on ServiceNow’s Enterprise AI Maturity Index, an annual measurement of how prepared organizations are to adopt and scale AI. To evaluate how Fortune 500 companies are rolling out AI and how much they value AI investments, Fortune teamed up with Enterprise Technology Research. The results went into computing an AIQ score for each company. Continue reading.

5. 10+ can't-miss Houston business and innovation events for October

From the fourth annual Tejano Tech Summit to the first-ever Ion Family Tech Festival, here's what not to miss this month. Image courtesy the Ion

Houston's October calendar is packed with informative and impactful events—plus a few fun ones, too. From the fourth annual Tejano Tech Summit to the first-ever Ion Family Tech Festival, here's what not to miss and how to register.Continue reading.

Here's what Houston lifestyle innovation news trended this year on InnovationMap. Image via Getty Images

Feature focused: 5 most-read Houston lifestyle innovation stories of the year

year in review

Editor's note: As the year comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. In the lifestyle category on InnovationMap, top stories included features on Houston startups with consumer-facing apps and reports related to life in Houston. Be sure to click through to read the full story.

A Louisiana-born, Houston-backed outdoors activity startup is expanding into the Bayou City

Mallard Bay, which won big at the Rice Business Plan Competition, is expanding in Houston. Photo via Getty Images

A Louisiana-founded hunting and fishing startup is growing its operations and expanding into Houston.

Mallard Bay, a marketplace for booking guided fishing and hunting trips, will move half of its employees to Houston and will join the Greater Houston Partnership, according to a release from the GHP. The company hopes the move will help it tap into the large corporate and convention entertainment market in Texas.

The company was founded in 2021 by a group of Louisiana State University students after noticing a gap in the outdoor travel space. Last year, founders Logan Meaux, Joel Moreau, Wyatt Mallett and Tam Nguyen entered in the Rice Business Plan Competition and won the fourth-most in investments and prizes, totaling $218,000.

“Entering the Rice Business Plan Competition helped close out our $1.8 million seed round last September,” Meaux, co-founder and CEO of Mallard Bay, says in a statement. “Not only did it help us raise money, but the recognition and the contacts we made were instrumental in growing the business and sparked the idea to expand to Houston. Prior to the competition, we were unaware of all that the Houston startup ecosystem had to offer, but quickly realized the value of having a network here in Houston.” Read the full story.

Houston could be 2nd biggest metro in U.S. by year 2100, new report says

Everyone wants to live here. Photo by Kevin Hernandez on Unsplash

Start spreading the news: Houston will eclipse New York City as the 2nd biggest metro area by the year 2100, a new report predicts.

An analysis by moving services site moveBuddha published June 22 says Houston's population could swell to 31.38 million people in the next 77 years.

Based on current population and migration trends, in fact, America’s three biggest metropolitan areas by 2100 will be Dallas-Fort Worth (No. 1), Houston (No. 2), and Austin (No. 3), replacing New York, Los Angeles, and Chicago as the country’s most populous metros, the report predicts. Read the full story.

Houston startup addresses mother-daughter dynamic with first app of its kind

A Houston-founded company is targeting mothers and daughters with their teletherapy app. Photo courtesy of Passport Journeys

When Lacey Tezino’s mother died of cancer she vowed to help other mothers and daughters find their own ways to bond in beautiful, nurturing ways.

Tezino turned that vow into a mission that is now available for others to embark on with an online therapy app tailored specifically for the mother-daughter dynamic Passport Journeys.

The Houston-based company is billed as the first mother-daughter teletherapy application that stands out in a crowded market place on online therapy like Better Help. Tezino, the founder and CEO, partnered with seven Houston-based licensed behavioral health clinics to make the dream a reality.

The app, which launched aptly on Mother's Day, can be downloaded via Apple or Google Play, and includes video therapy sessions, journal opportunities, interactive worksheets, and help those who need access to this form of mental health help with ease. Read the full story.

Houston again plummets on list of best places to live in new national report

Houston didn't even crack the top 100 in the new list. Photo by Alisa Matthews on Unsplash

In a surprise turn of events, Houston has fallen from grace in U.S. News and World Report's "Best Places to Live" ranking for 2023-2024.

Last year, Houston ranked No. 59 on the annual report — not surprising, considering all the Newstonians. However, the Bayou City plummeted to a shocking No. 140. Two years ago, the city ranked as No. 39, so this year's report represents a series of slips for Houston.

But why? According to the report: "A paycheck goes further in Houston than it does in other major metro areas, with affordable housing and free or cheap attractions like biking along Buffalo Bayou and exploring the 7,800-acre George Bush Park. The affordability of this region, which is located in southeastern Texas and home to more than 7 million residents in the metro area, is attracting new people from across the country and around the world." Read the full story.

Houston restaurant tech now serving optimized mobile ordering

This new restaurant technology allows for eateries to upgrade to mobile ordering for no cost. Photo courtesy of Cloche

A new Houston company has designed a platform that enables mobile ordering at no cost to restaurants.

Cloche, a mobile software platform named after the bell-shape dish cover that's known to come with room service orders, has launched in Houston and is currently looking for restaurants interested in utilizing their technology to upgrade their eatery with mobile ordering at no cost to the restaurant.

Alfredo Arvide, co-founder and managing director, tells InnovationMap that the idea for the platform came after the pandemic forced restaurateurs to quickly pivot to touch-free menus. Now that the consumer has adapted to scanning QR codes to view menus, the next step is to optimize ordering — something that will also help with the labor shortages that restaurants are now facing.

"Now is the time transform this industry by creating a better meal experience for the consumers, an easier job for the restaurant staff and a more efficient, more profitable business for restaurant owners," Arvide says. Read the full story.

Axiom Space's Houston Spaceport facility opens — and more top Houston innovation news. Photo courtesy of Houston Airports

Startup-sourced gift ideas, Houston Spaceport's newest facility opens, and more trending innovation news

5 top trending innovation stories in Houston this week

What you're reading

Editor's note: Welcome to the inaugural edition of our weekly top stories roundup. Here's where you can see what's being read across InnovationMap. This week, futuristic gift ideas, DNA dating, top events, and more are catching the eyes of our readers.

10 futuristic products you can buy today in this Galleria store that's flipping the script on retail

B8ta has all the perks of a digital marketplace — but customers are able to physically test all the products. Photo by Natalie Harms

B8ta, which has its lone Houston store in the Galleria, will stock any types of products in its stores, as long as it fits the bill as an innovative product. Here are 10 that seem like are from the future. Read the full story here.

5 can't-miss Houston events for entrepreneurs to close out 2018

Check out these conferences, shopping events, networking, and more. Getty Images

Before most of Houston completely checks out for the holidays, the city is playing host to a few major innovation-focused events. Learn from thought leaders, network, and even shop at these five events taking place this week and next. Read the full story here.

Houston DNA-based dating app expands nationwide, launches next funding round

Pheramor takes users' DNA and social media habits and matches them with compatible partners. Courtesy of Pheramor

Houston singles can find their perfect match — even if it's someone across the country. Houston-based Pheramor — a DNA-based dating app — is available for download in every state. Read the full story here.

Life Time reveals details of first Houston coworking space

Houston snags only the third location of Life Time Work. It opens in City Centre early next year. Courtesy of Life Time

Houston is just the third city to be chosen to have a location of Minnesota-based Life Time's new coworking center. Life Time Work should be open in early 2019 in City Centre Five, adjacent to Life Time Athletic. Read the full story here.

3 Houston innovators to know this week

These three entrepreneurs are in the business of solving problems. Courtesy photos

Entrepreneurs see a problem, and solve it. This week's three innovators to know are no different. All three have personal stories of realizing there's something not right — and there's something they could do about it. Read the full story here.

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Rice, Houston Methodist developing soft 'sleep cap' for brain health research

Researchers and scientists at Rice University and Houston Methodist are developing a “sleep cap” that aims to protect the brain against dementia and other similar diseases by measuring and improving deep sleep.

The project is a collaboration between Rice University engineering professors Daniel Preston, Vanessa Sanchez and Behnaam Aazhang; and Houston Methodist neurologist Dr. Timea Hodics and Dr. Gavin Britz, director of the Houston Methodist Neurological Institute and chairman of the Department of Neurosurgery.

According to Rice, deep sleep is essential for clearing waste products from the brain and nightly “cleaning cycles” help remove toxic proteins. These toxic proteins, like amyloids, can accumulate during the day and are linked to Alzheimer’s disease and other neurological issues.

Aazhang, director of the Rice Neuroengineering Initiative, and his team are building a system that not only tracks the brain’s clearing process but can also stimulate it, improving natural mechanisms that protect against neurodegeneration.

Earlier proof-of-concept versions of the caps successfully demonstrated the promise of this approach; however, they were rigid and uncomfortable for sleep.

Preston and Sanchez will work to transform the design of the cap into a soft, lightweight, textile-based version to make sleep easier, while also allowing the caps to be customizable and tailored for each patient.

“One of the areas of expertise we have here at Rice is designing wearable devices from soft and flexible materials,” Preston, an assistant professor of mechanical engineering, said in a news release. “We’ve already shown this concept works in rigid device prototypes. Now we’re building a soft, breathable cap that people can comfortably wear while they sleep.”

Additionally, the research team is pursuing ways to adapt their technology to measure neuroinflammation and stimulate the brain’s natural plasticity. Neuroinflammation, or swelling in the brain, can be caused by injury, stroke, disease or lifestyle factors and is increasingly recognized as a driver of neurodegeneration, according to Rice.

“Our brain has an incredible ability to rewire itself,” Aazhang added in the release. “If we can harness that through technology, we can open new doors for treating not just dementia but also traumatic brain injury, stroke, Parkinson’s disease and more.”

The project represents Rice’s broader commitment to brain health research and its support for the Dementia Prevention Research Institute of Texas (DPRIT), which passed voter approval last week. The university also recently launched its Rice Brain Institute.

As part of the project, Houston Methodist will provide access to clinicians and patients for early trials, which include studies on patients who have suffered traumatic brain injury and stroke.

“We have entered an era in neuroscience that will result in transformational cures in diseases of the brain and spinal cord,” Britz said in the release. “DPRIT could make Texas the hub of these discoveries.”

Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.

Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.

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