A Houston-based fintech company has taken a huge step in the right direction for growth. Getty Images

Houston-based fintech company HighRadius Corp. has forged a partnership with Canadian conglomerate Thomson Reuters Corp. that will open up more markets for its enterprise software-as-a-service.

The partnership equips HighRadius to tap into the global network of Confirmation.com, a unit of Thomson Reuters. Confirmation's network features more than 1,000 banks. Credit managers at those banks will be able to use HighRadius' software to automate the credit process for online credit applications.

"This partnership will allow us to expand our credit inquiry solution to new markets," Mark Portanova, Confirmation.com's vice president of sales for the Americas, says in a release. "We will enhance workflows, reporting capabilities, and client authorization processes within the HighRadius platform. These measures will progress the traditionally slow, manual, and time-consuming credit approval processes … ."

HighRadius' AI-powered software is designed to streamline accounts-receivable and cash-management processes. For instance, HighRadius' Cash Application software relies on AI to comb through documents like emails and invoices to automatically match incoming payments with customers' accounts.

Sayid Shabeer, chief product officer at HighRadius, says the company's suite of product ultimately lets companies free up millions of dollars in working capital and reallocate employees' time to higher-value tasks.

Among HighRadius' customers are corporate heavyweights like healthcare giant Johnson & Johnson, apparel maker adidas, food company Danone, and Dr Pepper Snapple Group. In January, HighRadius reported it had passed the 350-customer mark last year and doubled the size of its European workforce.

"2018 was the year that the bets we've been making over the last few years started to pay off in scale," Sashi Narahari, founder and CEO of HighRadius, says in a release.

Among HighRadius' competitors are Billtrust, Rimilia Holdings, Cforia Software, and Financial National Information Services. The global market for credit management software is forecast to exceed $2.1 billion by 2022, up from $636.4 million in 2017.

HighRadius, founded in 2006, employs more than 1,000 people in North America, Europe, and Asia. Since its inception, HighRadius has raised more than $50 million from Philadelphia-based Susquehanna Growth Equity, and has collected strategic investments from banking behemoths Citi and PNC.

HighRadius recently hired Jon Keating as vice president and general manager of its Europe, Middle East, and Africa (EMEA) markets. Keating most recently was chief sales officer at San Francisco fintech company Taulia. Earlier in the year, the company tapped SaaS veteran Natalie Fedie as vice president of customer success to help propel its global growth.

"HighRadius continues to invest in talent across Europe and Asia to fuel its growth plans and keep ahead of the innovation curve," Shabeer says.

Last year, HighRadius moved its headquarters to 200 Westlake Park Blvd. in the Energy Corridor. More than 150 employees relocated there. HighRadius subleases the space from BP America.

"The expansion of HighRadius into the Katy area represents another high-tech company choosing to mature in our community," Lance LaCour, president and CEO of the Katy Area Economic Development Corp., said at the time. "HighRadius is projected to have an estimated regional economic impact of over $600 million over a five-year period."

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.