A Texas organization has doled out millions to Houston cancer-fighting professionals

granted

Texas doctors and researchers received millions for their transformational work in cancer prevention and treatment. Getty Images

Researchers at medical institutions across the state have something to celebrate. The Cancer Prevention and Research Institute of Texas has made 71 grants this week to cancer-fighting organizations that total a near $136 million.

"CPRIT's priorities of pediatric cancer research and cancers of significance to Texans highlight this large slate of awards," says Wayne Roberts, CPRIT CEO, in a release. "Investments are made across the cancer research and prevention continuum in Texas unlike any other state in the country."

New to the awards this time around is the Collaborative Action Program for Liver Cancer, which has been claimed by Baylor College of Medicine's Hashem B. El-Serag.

"Texas has the highest incidence rates of hepatocellular cancer in the nation," El-Serag says in a release from BCM. "Our CPRIT funded Center will house infrastructure to support and enhance research collaborations among liver cancer researchers; to educate providers, researchers and the general public on best practices and opportunities to reduce the burden of liver cancer; and to engage private and public entities in policy initiatives."

Houston organizations also received recruitment awards, which reward Texas organizations for bringing in great minds from across the world. According to the release, CPRIT has brought in a total of 181 scholars and 13 companies to the Lone Star State.

Of the 71 grants, 58 represent academic research, 10 prevention, and three product development research. Here are the ones awarded to Houston organizations.

The University of Texas MD Anderson Cancer Center

$900,000 granted for Shao-Cung Sun's research in regulation of CD8 T cell responses in antitumor immunity (Individual Investigator Research Award)
$897,483 granted for Alemayehu A. Gorfe's research in characterization and optimization of novel allosteric KRAS inhibitors (Individual Investigator Research Award)
$3 million granted for Hashem B. El-Serag's research at The Texas Collaborative Center for Hepatocellular Cancer (Collaborative Action Program to Reduce Liver Cancer Mortality in Texas: Collaborative Action Center Award)
$2.46 million to Jessica Hwang for patient-centered liver cancer prevention in the Houston community (Collaborative Action Program to Reduce Liver Cancer Mortality in Texas: Investigator-Initiated Research Awards)
$3.51 million for Kevin McBride's Recombinant Antibody Production Core at Science Park
$199,804 granted for Andrea Viale's epithelial memory of resolved inflammation as a driver of pancreatic cancer progression (High Impact High Risk Award)
$6 million for the recruitment of Christopher Flowers, M.D. (Recruitment of Established Investigator Awards)
$2 million for the recruitment of Kevin Nead, MD, MPhil (Recruitment of First-Time, Tenure-Track Faculty Members Awards)
$2 million for the recruitment of Alison Taylor, PhD (Recruitment of First-Time, Tenure-Track Faculty Members Awards)
$2 million for the recruitment of Mackenzie Wehner, MD, MPhil (Recruitment of First-Time, Tenure-Track Faculty Members Awards)

Baylor College of Medicine

$5.38 million granted for Steven J. Ludtke's new capabilities for cancer research in the TMC CryoEM Cores (Core Facility Support Awards)
$1.35 million granted for Bryan M. Burt's novel endoscope-cleaning port for minimally invasive cancer surgery (Early Translational Research Awards)
$199,500 granted for Yohannes T. Ghebre's Topical Esomeprazole for Radiation-induced Dermatitis (High Impact High Risk Award)
$199,920 granted for Robin Parihar's targeting of cancer associated fibroblasts with anti-IL-11-secreting CAR T cells (High Impact High Risk Award)
$2 million for the recruitment of Umesh Jadhav, PhD (Recruitment of First-Time, Tenure-Track Faculty Members Awards)
$2 million for the recruitment of Stanley Lee, PhD (Recruitment of First-Time, Tenure-Track Faculty Members Awards)
$2 million for the recruitment of Ang Li, MD (Recruitment of First-Time, Tenure-Track Faculty Members Awards)
$1.29 million for Jane R. Montealegre's expansion of "a Community Network for Cancer Prevention to Increase HPV Vaccine Uptake and Tobacco Prevention in a Medically Underserved Pediatric Population"

Texas Medical Center

$5.44 million granted for William McKeon's Business-Driven Accelerator for Cancer Therapeutics (Core Facility Support Awards)

The University of Texas Health Science Center at Houston

$5.95 million granted for Zhiqiang An's Advanced Cancer Antibody Drug Modalities Core Facility (Core Facility Support Awards)
$2 million granted for Qingyun Liu's discovery and development of novel peptibody-drug conjugate for treating cancers of the digestive system (Early Translational Research Awards)
$199,998 granted for Leng Han's expression landscape and biomedical significance of transfer RNAs in cancer (High Impact High Risk Award)
$2 million for Lara S. Savas' Salud en Mis Manos that delivers "Evidence-Based Breast & Cervical Cancer Prevention Services to Latinas in Underserved Texas South and Gulf Coast Communities"

The University of Texas Medical Branch at Galveston

$3.55 million granted for William K. Russell's A Targeted Proteomics and Metabolomics Mass Spectrometry Core Facility at the University of Texas Medical Branch at Galveston (Core Facility Support Awards)
$199,996 granted for Brendan Prideaux's novel cellular-level imaging approach to assess payload drug distribution in tumors following administration of targeted drug delivery systems (High Impact High Risk Award)
$200,000 granted for Casey W. Wright's targeting ARNT and RBFOX2 alternative splicing as a novel treatment modality in lymphoid malignancies (High Impact High Risk Award)

The Methodist Hospital Research Institute

$200,000 granted for Robert Rostomily's development of a mini-pig glioma model and validation of human clinical relevance (High Impact High Risk Award)

Texas Southern University

$200,000 for Song Gao's alleviating SN-38-induced late-onset diarrhea by preserving local UGTs in the colon (High Impact High Risk Award)

University of Houston

$200,000 granted for Sergey S. Shevkoplyas' Novel High-Throughput Microfluidic Device for Isolating T-cells Directly from Whole Blood to Simplify Manufacturing of Cellular Therapies (High Impact High Risk Award)

Rice University

$2 million for the recruitment of Jiaozhi (George) Lu, PhD (Recruitment of First-Time, Tenure-Track Faculty Members Awards)
$1.67 million for the recruitment of Vicky Yao, PhD (Recruitment of First-Time, Tenure-Track Faculty Members Awards)

The Rose

$2 million for Bernice Joseph's Empower Her To Care Expansion

Legacy Community Health Services

$999,276 for Charlene Flash's "Increasing Breast and Colorectal Cancer Screening Rates for the Medically Underserved using Population Health Strategies at a Multi-County FQHC"

The design and construction team has been announced for TMC3. Courtesy of Elkus Manfredi Architects

Texas Medical Center reveals new details and renderings for its TMC3 campus

Coming to hou in 2022

The Texas Medical Center just announced the dream team of architects and designers that are making TMC3 into a reality.

Elkus Manfredi Architects, Transwestern, and Vaughn Construction are the three companies that will serve as the architectural and development team for the 37-acre research campus. TMC3's founding institutions — TMC, Baylor College of Medicine, Texas A&M University Health Science Center, The University of Texas Health Science Center at Houston, and The University of Texas MD Anderson Cancer Center — decided on the three entities.

"Texas Medical Center is eager to move forward with a bold, imaginative and dynamic new design vision for the TMC3 Master Plan," says TMC CEO and president, Bill McKeon, in a press release. "With the combined talents of Elkus Manfredi Architects, Transwestern, and Vaughn Construction on-board, I couldn't be more confident that this dream team will flawlessly execute the totality of the project's vision and fulfill its mission to bring together leading researchers and top-tiered expertise from the private sector to create the number one biotechnology and bioscience innovation center in the entire world."

TMC3 was first announced just over a year ago and is planned to open in 2022. The campus will incorporate research facilities, retail space, residential plans, a hotel and conference center, and green space. Parking will be underground to optimize surface area.

Design in mind

The 37-acre research campus will be interconnected by a DNA helix outdoor promenade.

Courtesy of Elkus Manfredi Architects

From a design perspective, the key element will be a DNA helix-shape that looks like a necklace chain that connects the campus.

"Our idea was to expand on the DNA design concept and create a series of spaces that would elongate the strand all the way north to the historic core of the Texas Medical Center and south to the new development by UTHealth and MD Anderson in order to create more opportunity for connections and collisions," says Elkus Manfredi Architects CEO and founding principal, David Manfredi, in the release. "We're implementing the connective tissue between all these places and establishing opportunities for unplanned interactions. Science, technology, medicine, discovery and innovation are all about making connections, and we are building a space for institutions, industry and startups to interact."

Manfredi's firm is responsible for a few other iconic medical facilities, such as the original Broad Institute of MIT and Harvard and The Stanley Building at the Broad Institute in Cambridge, Massachusetts, and the New York Genome Center.

"We want to create spaces that attract talent," Manfredi says in the release. "You can attract talent with great colleagues, research and facilities, but if you don't have a great social environment for people to live, learn, and play, people move on. We are creating a place where people will want to be because they're constantly stimulated – whether it's breakfast at the local coffee shop, or a volleyball league in the afternoon, or working in a central lab and the person next to them is doing something intersects with their own research."

Growing partner institutions

TMC3 Collaborative will be a centrally located building on the campus that is designed to host gatherings and share space with industry leaders.

Courtesy of Elkus Manfredi Architects

While a big portion of the attraction in the new campus is this multi-purposeful and connective space, the project opens doors for the five partner institutions. For Baylor College of Medicine, TMC3 means an expansion of its facilities and an increased footprint for Baylor St. Luke's Medical Center's McNair Campus. The second tower of the hospital will be right at TMC3's eastern edge.

"The selection of a development team is an important milestone for the TMC3 project," says Paul Klotman, president, CEO and executive dean of Baylor College of Medicine, in the release. "The project itself is a huge step in developing the biotech industry in Houston. At Baylor, we look forward to working closely with TMC leaders, as well as those of the other anchor institutions, in making this project a reality."

Additionally, the Texas A&M Health Science Center research building — led by Carrie L. Byington, M.D — on the north end adjacent to BCM's building and the hotel and conference center. On the south side of the campus, MD Anderson and UTHealth will each develop new research facilities that will connect to the existing University of Texas Research Park that is directly to the south of the campus. UT Research Park will be connected to TMC3 via a new skybridge.

The release also describes a central building dubbed TMC3 Collaborative that will create collaborative research space for industry partners. The first level of the building will be an open atrium for gatherings and have food and beverage concepts.

"When TMC3 opens in 2022, Texas Medical Center will officially plant a tangible flag that signals its arrival as the Third Coast for life sciences for the foreseeable future," McKeon says in the release.

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10+ can't-miss Houston business and innovation events for April

WHERE TO BE

From pitching competitions to expert speaker summits, April is filled with opportunities for Houston innovators.

Here's a roundup of events you won't want to miss out on so mark your calendars and register accordingly.

Note: This post may be updated to add more events.

April 4 — Mission Control: Texas’ Leadership in Space, Technology, and Innovation

Since its inception, the space industry has expanded across Texas and grown beyond scientific exploration into a tableau on which the terrestrial set have placed bets related to tourism, mining, communications, healthcare, food science, national security, technical innovations across all industries, and even human habitation beyond earth. The Texas Lyceum’s 2024 Public Conference (PubCon) will explore these opportunities and the journey to realize the promise of space and beyond for Texas and the nation.

Throughout the event, an expected 300 industry leaders and Texas legislators and staffers will participate in thought provoking discussions to inform our stakeholders and state leaders on the trajectory, challenges and opportunities in the Space Economy.

This event starts Thursday, April 4, from 2:30 to 9:30 pm at the Thompson Hotel. Click here to register.

April 4-6 — 2024 Rice Business Plan Competition

Hosted and organized by the Rice Alliance for Technology and Entrepreneurship, which is Rice University's internationally-recognized initiative devoted to the support of entrepreneurship, and Rice Business, the Rice Business Plan Competition offers an educational program mirroring real-world experience through this multi-day event for student startups from across the world.

In total, more than $1 million in investment and cash prizes are expected to be awarded at the 2024 Rice Business Plan Competition. Every single startup will walk away with at least $950 in cash prizes, no matter where they place in the competition.

The Elevator Pitch event is open to the public and on Thursday, April 4, from 6 to 9 pm at Jones Graduate School of Business. Click here to register.

April 6 — 12th Annual Houston Global Health Collaborative Conference

This meeting is an annual gathering of interdisciplinary professionals and students with a passion for global health innovation and advancement. This year's Conference Theme is Global Health Diplomacy: Shaping Policies for Health Impact and will feature subthemes of vaccine diplomacy, global surgery, the prevalence of non-communicable diseases, and the global nutrition crisis. Clinicians, researchers, healthcare workers, policymakers, and students across any field who are interested in global health are especially encouraged to attend.

This event is Saturday, April 6, from 7:45 am to 7 pm at the University of Houston College of Medicine. Click here to register.

April 10 — Bayou City Bio Pulse

Check out a showcase of life sciences in The Woodlands. This event will feature a vendor exhibition, presentations from business, academic and community development leaders, and a panel discussion on The Woodlands’ life sciences ecosystem. Spanning across five sites totaling over 80 acres, The Woodlands Innovation District is positioned to meet the needs of companies focused on in-house manufacturing (from biopharma to industrial biology), as well as contract development manufacturing organizations (CDMOs).

This event is Wednesday, April 10, from 8 am to 12 pm at the Woodlands Towers. Click here to register.

April 18 — Energy Underground: All Things Hydrogen

The Energy Underground is a group of professionals in the Greater Houston area that are accelerating the Energy Transition. Come together to learn and support each other's work in advancing the Energy Transition: make industry contacts, secure financing, share deals, recommend talent looking to enter the energy workforce, and anything else that leads to bigger, better energy companies.

This event is Thursday, April 18, from 12 to 1:30 pm at the Cannon West Houston. Click here to register.

April 19 — Build Day x Tour: Houston Hackathon

A partnership between ACT House, a human analytics leader, and Tech Equity Collective, a Google Initiative driving black innovation in tech formed an exciting new accelerator. Participants will build their own startup team, collaborate on ideas, and sprint on real work. The first place winning team will receive $10,000, the second place team will recieve $5,000 and the third place team will get $2,500.

This event is Friday, April 19, at 4 pm until April 20 at 4 pm. Click here to register.

April 21 — The Energy Corridor District's Earth Day Celebration

Come out for a day of fun and environmental awareness. Get hands-on and contribute to a communal art piece that symbolizes a collective commitment to Mother Earth. Pick up a brush or a marker and add your creativity to the canvas.

Take a moment to learn how the world's top energy companies are contributing to a more sustainable future. Get inspired and pick up some tips for your own eco-journey

This event is Sunday, April 21, from 1 to 4 pm at Terry Hershey Park. Click here to register.

April 22 — EO4Energy Workshop

The Geological Remote Sensing Group (GRSG) Americas, in partnership with the University of Houston, invites you to a workshop focusing on the role of Earth Observation (EO) and remote sensing in the Energy Industry.

As the industry moves towards sustainability, driven by Environmental, Social, and Governance (ESG) considerations, the significance of EO and remote sensing continues to grow. This workshop will encompass insightful case studies, introduce emerging technologies, and present advanced methodologies. Participants will engage with a diverse group of professionals from the energy, space, academic, and government sectors.

This event begins Monday, April 22, at 8 am at Hilton University of Houston. Click here to register.

April 25 — 2024 PIDX International US Spring Conference

In this industry event, explore the intersection of AI and Digital Standards. All experienced speakers across industries are invited to contribute articles, share use cases and theories, and connect with attendees from the Energy Industry.

The accumulated knowledge shared at the event will guide the forthcoming phase of PIDX Standards Development tailored for the Energy Industry.

This event begins Thursday, April 25, at 8 am at 501 Westlake Park. Click here to register.

April 26 — StartupLaunch USA: Ignite Your Entrepreneurial Journey

This is an immersive online learning experience tailored for aspiring entrepreneurs looking to kickstart their startup ventures in the United States. This event provides participants with the essential knowledge, skills, and resources needed to navigate the complexities of launching and scaling a successful business.

Through a series of interactive workshops, expert-led seminars, and practical case studies. Participants will learn how to develop innovative business ideas, validate market opportunities, and create viable business models that resonate with target audiences.

This event is Friday, April 26, from 1 to 6 pm at Museum of Natural Science. Click here to register.

April 27 — World Youth Foundation: STEAM Innovation Incubator

WYF's STEAM Innovation Industry Pathways, or SIIP, is a youth out-of-school-time monthly program designed to bridge the gap between academic learning, industry, and digital skilling.

Open to youth ages 6 to 24, SIIP is not your typical program—it's a gateway to a world of metaskilling, offering a dynamic range of skills from design thinking, strategic project management, soft skills development, digital skills development, and industry application.

This event is Saturday, April 27, from 10 am to 1:30 pm at Sunnyside Health and Multi-Service Center. Click here to register.

Report: Here's how Houston ranks in terms of its gender pay gap

by the numbers

It's 2024 and women are still making less money than men, thus keeping the unfortunate reality of the wage gap alive. But at least in Houston, the wage gap isn't as bad as other Texas cities, according to a new earnings study by Chamber of Commerce.

Houston ranked No. 142 on the list, which examined earnings for full-time workers in 170 of the most populous cities in the United States.

The study found that, in 2024, men in Houston are currently making $4,474 more than women — a figure that's significantly lower than the national wage gap, which is a little over $11,000.

The U.S. city with the worst gender pay gap is none other than Frisco, a Dallas suburb. Men in Frisco are currently making a staggering $52,216 more than women, which is more than $12,000 more than the gap in 2023.

Also in North Texas, McKinney remained in the No. 5 spot for the second consecutive year. McKinney men make $24,568 more than women, which is a $4,400 decrease year-over-year. Plano's gender wage gap has worsened since 2023: The Dallas suburb is now listed among the top 10 worst pay gaps in the U.S., climbing to No. 6. The study says the Plano's wage gap is now $23,415, or nearly $2,300 more than last year.

Statewide gender pay gap

Chamber of Commerce found that Texas' gender pay gap has increased since last year; The 2023 study found that women made nearly $11,000 less than men, and that discrepancy has widened in 2024 to nearly $12,000.

However, Texas' ranking has improved 10 spots from No. 29 last year to No. 19 this year.

For added context, New Hampshire has the No. 1 worst pay gap in the nation, with men making over $18,000 more than women.

Other Texas cities that earned spots in the report are:

No. 20 – Amarillo
No. 22 – Laredo
No. 24 – Austin
No. 30 – Corpus Christi
No. 31 – Pasadena
No. 33 – Irving
No. 52 – Lubbock
No. 59 – El Paso
No. 65 – Grand Prairie
No. 81 – Fort Worth
No. 118 – Dallas
No. 121 – San Antonio
No. 125 – Arlington
No. 167 – Brownsville
No. 168 – Garland

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This article originally ran on CultureMap.

3 Houston innovators to know this week

who's who

Editor's note: Welcome to another Monday edition of Innovators to Know. Today I'm introducing you to three Houstonians to read up about — three individuals behind recent innovation and startup news stories in Houston as reported by InnovationMap. Learn more about them and their recent news below by clicking on each article.

Sean Kelly, CEO and co-founder of Amperon

Amperon CEO Sean Kelly joins the Houston Innovators Podcast to share his company's growth and expansion plans. Photo via LinkedIn

The technology that Amperon provides its customers — a comprehensive, AI-backed data analytics platform — is majorly key to the energy industry and the transition of the sector. But CEO Sean Kelly says he doesn't run his business like an energy company.

Kelly explains on the Houston Innovators Podcast that he chooses to run Amperon as a tech company when it comes to hiring and scaling.

"There are a lot of energy companies that do tech — they'll hire a large IT department, they'll outsource a bunch of things, and they'll try to undergo a product themselves because they think it should be IP," he says on the show. "A tech company means that at your core, you're trying to build the best and brightest technology." Continue reading.

Amanda Burkhardt, CEO of Phiogen

Spun out of Baylor College of Medicine, Phiogen was selected out of 670 companies to pitch at SXSW earlier this month. Photo via LinkedIn

A new Houston biotech company won a special award at the 16th Annual SXSW Pitch Award Ceremony earlier this month.

Phiogen, one of 45 companies that competed in nine categories, was the winner for best inclusivity, much to the surprise of the company’s CEO, Amanda Burkhardt.

Burkhardt tells InnovationMap that while she wanted to represent the heavily female patient population that Phiogen seeks to treat, really she just hires the most skilled scientists.

“The best talent was the folks that we have and it ends up being we have three green card holders on our team. As far as ethnicities, we have on our team we have Indian, African-American, Korean, Chinese Pakistani, Moroccan and Hispanic people and that just kind of just makes up the people who helped us on a day-to-day basis,” she explains. Continue reading.

Mielad Ziaee, 2023-2024 All of Us Research Scholar

Mielad Ziaee, a 20-year-old student at the University of Houston, was tapped for a unique National Institutes of Health program. Photo via UH.edu

A Houston-area undergraduate student has been tapped for a prestigious national program that pairs early-career investigators with health research professionals.

Mielad Ziaee was selected for the National Institutes of Health’s 2023-2024 All of Us Research Scholar Program, which connects young innovators with experts "working to advance the field of precision medicine," according to a statement from UH. Ziaee – a 20-year-old majoring in psychology and minoring in biology, medicine and society who plans to graduate in 2025 — plans to research how genomics, or the studying of a person's DNA, can be used to impact health.

“I’ll be one of the ones that define what this field of personalized, precision medicine will look like in the future,” Ziaee said in a statement. “It’s exciting and it’s a big responsibility that will involve engaging diverse populations and stakeholders from different systems – from researchers to health care providers to policymakers.” Continue reading.

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