This is a Houston resident's sign to launch that small business they've been dreaming of. Photo by Mickey Dziwulski on Unsplash

Houstonians whose New Year's resolution is to start their own small business will be happy to learn they're in the right city to do it. Houston-The Woodlands-Sugar Land has been ranked among the 25 best metropolitan areas to start a small business in a new report.

The report by personal finance website The Credit Review placed Houston in the No. 22 spot, touting the city's rapid growth, its diverse economy, and its ever-expanding population as several attractive reasons for its rank.

Small business owners in Houston specifically thrive in the arts, entertainment, and recreation sectors, the report found. Houston has proved its big on business, as several major employers have invested in the city while earning high recognition for their efforts in improving the workplace atmosphere for employees.

With the shift to remote work, it's now much easier for Houston residents to launch their business than ever before, the report claims. But in order to ensure longevity with a small business, the study suggests launching the venture in a place with the right number of resources and connections.

"The more resources a small business owner has, the better chances they have to succeed," the report says. "This is why, despite the overall shift to a remote-centric world, geographic location matters more than ever for a small business’s long-term success."

Austin-Round Rock-Georgetown earned the gold medal as the No. 1 metro for starting a small business. The Central Texas region is also the No. 1 hotspot for businesses in the information services sector, and the arts, entertainment, and recreation industry.

Another thriving Texas metro that earned a spot in the top 10 is Dallas-Fort Worth-Arlington, claiming the No. 8 spot. Elsewhere in Texas, San Antonio-New Braunfels ranked below Houston as No. 32.

The top 10 U.S. metros for starting a small business are:

  • No. 1 – Austin-Round Rock-Georgetown, Texas
  • No. 2 – Provo-Orem, Utah
  • No. 3 – Raleigh-Cary, North Carolina
  • No. 4 – Salt Lake City, Utah
  • No. 5 – Boise, Idaho
  • No. 6 – Nashville-Davidson-Murfreesboro-Franklin, Tennessee
  • No. 7 – Jacksonville, Florida
  • No. 8 – Dallas-Fort Worth-Arlington, Texas
  • No. 9 – Charlotte-Concord-Gastonia, North Carolina-South Carolina
  • No. 10 – North Port-Sarasota-Bradenton, Florida

The report analyzed the top 100 U.S. metro regions across 10 factors to determine the rankings, including unemployment rates, growth rates, new business success rates, and more.

The full report can be found on thecreditreview.com.

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This article originally ran on CultureMap.

The No. 1 city on the list was from Texas, but it wasn't Houston. Photo via Getty Images

Texas cities see mixed results on list of top markets to start a business

progress report

While the Lone Star State secured top marks for states to launch a company, Houston was a bit outpaced by two of its sister cities.

According to a study by The Credit Review, a personal finance website, Texas was one of the best states in which to start a small business in 2023. In fact, Austin was the No. 1 city in the list entitled "25 Best U.S. Metros to Start a Small Business in High-Growth Sectors," which came out at the end of November.

“There are so many reasons why Austin is the best place to start a small business that it would require another article to explain them all,” the article reads.

Austin grabbed the top spot as the best city to start a small business in America in the top five sectors, including arts, entertainment, and recreation; and information services.

But that’s not the only reason that Texas was a winner. Dallas was No. 8 on the list for its fast growth in the area of management of companies and enterprises, while Houston was No. 22.

On the other hand, McAllen and El Paso were among the worst places in the country to start a small business. With McAllen’s 29.3 percent poverty rate, it comes in last for the entire country.

The Credit Review, which hails from Austin, compared the 100 largest MSAs in the United States for fast-growth and small business-survivability indicators such as population change, GDP, and the state of fastest-growing business sectors based on growth projections for 2021-2031 in each MSA. The team’s sources include the U.S. census, U.S. Bureau of Labor Statistics, Tax Foundation, and U.S. Courts.

It's worth noting that Houston’s GDP per capita score was one of the highest on the list, 8.9 out of 10. (Austin’s was 9.3.) The metro area, which also included Sugarland and The Woodlands, was noted for its top sector, arts, and entertainment.

Earlier this year, Texas ranked highly on two separate lists evaluating the best states to start a business. In January, the state ranked No. 3 on WalletHub's annual report, and then in April, Texas cinched No. 3 on Credit on Tap's ranking.

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Axiom Space-tested cancer drug advances to clinical trials

mission critical

A cancer-fighting drug tested aboard several Axiom Space missions is moving forward to clinical trials.

Rebecsinib, which targets a cancer cloning and immune evasion gene, ADAR1, has received FDA approval to enter clinical trials under active Investigational New Drug (IND) status, according to a news release. The drug was tested aboard Axiom Mission 2 (Ax-2) and Axiom Mission 3 (Ax-3). It was developed by Aspera Biomedicine, led by Dr. Catriona Jamieson, director of the UC San Diego Sanford Stem Cell Institute (SSCI).

The San Diego-based Aspera team and Houston-based Axiom partnered to allow Rebecsinib to be tested in microgravity. Tumors have been shown to grow more rapidly in microgravity and even mimic how aggressive cancers can develop in patients.

“In terms of tumor growth, we see a doubling in growth of these little mini-tumors in just 10 days,” Jamieson explained in the release.

Rebecsinib took part in the patient-derived tumor organoid testing aboard the International Space Station. Similar testing is planned to continue on Axiom Station, the company's commercial space station that's currently under development.

Additionally, the drug will be tested aboard Ax-4 under its active IND status, which was targeted to launch June 25.

“We anticipate that this monumental mission will inform the expanded development of the first ADAR1 inhibitory cancer stem cell targeting drug for a broad array of cancers," Jamieson added.

According to Axiom, the milestone represents the potential for commercial space collaborations.

“We’re proud to work with Aspera Biomedicines and the UC San Diego Sanford Stem Cell Institute, as together we have achieved a historic milestone, and we’re even more excited for what’s to come,” Tejpaul Bhatia, the new CEO of Axiom Space, said in the release. “This is how we crack the code of the space economy – uniting public and private partners to turn microgravity into a launchpad for breakthroughs.”