The Rice Alliance and BioHouston acknowledged innovations from a dozen promising health tech companies. Photo via Rice University

For the 13th year, the Texas Life Science Forum hosted by BioHouston and the Rice Alliance for Technology and Entrepreneurship celebrated innovative companies from around the world that are creating new treatments and solutions to today's biggest health care challenges.

This week, over 40 companies presenting their innovations across cancer, cardiovascular disease, biotechnology, and more. Nearly 700 venture capitalists, corporate innovation groups, angel networks, industry leaders, academics, service providers, and others attended the event on November 7 at Rice's BioScience Research Collaborative in the Texas Medical Center.

Just like in previous years, the event ended with the announcement of the 10 companies that were deemed "most promising" based on their pitches and technologies. Of the 10 companies named, six are headquartered in Houston and an additional two startups on the list have a presence here.

The 2024 most-promising life science companies are:

Houston-based clinical-stage cell therapy company March Biosciences is developing a pipeline of innovative therapies, beginning with targeting relapsed an refractory T cell lymphoma.

ImmunoGenesis, headquartered in Houston, is a clinical-stage biotechnology company developing a potent PD-1 pathway targeting agent specifically engineered for immuneexcluded tumors, which account for over 50 percent of all cancers

Taurus Vascular, based in Houston, is revolutionizing endovascular aneurysm repair by addressing the critical issues of residual aneurysm pressurization and endoleaks with its catheter-deployable aortocaval shunt.

Headquartered in Australia with a Houston presence, Foxo Technology offers HIPAA-compliant, communication software for anyone in health care.

Another Houston company, Voythos has built an AI platform to better predict and diagnose cardiovascular disease earlier to enhance quality and cost of care.

Dutch company Loop Robot, which has a presence in Houston, automates disinfection with its intelligent robot to make medical-grade disinfection faster, safer, and digitally auditable.

London-based Case45 develops and commercializes pan-cancer prognostic tests using unique integration of tumor evolution and AI and is beginning with breast and lung cancers.

OmniNano Pharmaceuticals, headquartered in Houston, has developed a nano-drug delivery platform technology enables simultaneous co-delivery of multiple therapeutic agents designed specifically to treat solid tumors.

Houston-based clinical-stage biopharmaceutical company Mongoose Bio is pioneering first-in-class T cell receptor T cell (TCR-T) therapies for cancer treatment.

Rua Diagnostics from New York is redefining point-of-care diagnostics with advanced micro gas chromatography technology for breath analysis that's capable of detecting a wide range of prevalent and deadly diseases.

In addition to this list, the event named two additional awards. United Kingdom's Cytecom, which provides quick and accurate diagnosis and treatment of blood infections stems, was selected by the crowd as the People's Choice award winner.

Last, but not least, BioHouston's Ann Tanabe awarded this year's Michael E. Debakey Award to Houston-based Autoimmunity BioSolutions, seed-stage biotech developing a next-generation, immuno-corrective therapy for treatment of autoimmune diseases to restore normal immune function.

Eight of the 10 most-promising life science startups named at BioHouston and the Rice Alliance's event are based in Houston. Photo courtesy of Rice Alliance

Houston startups named most promising in the life science space at annual event

ones to watch

For the second time this year, Houston life science leaders and startup founders gathered to discuss the future of health care in Houston.

The annual Texas Life Science Forum hosted by BioHouston and the Rice Alliance for Technology and Entrepreneurship was usually held during the fall before the pandemic pushed it off schedule. In February, the two organizations hosted the previous forum, but as of this month, the annual event is back on track.

The day included panels and networking, plus over 50 companies — about half of which are based in Houston — pitched their solutions across medical device, therapeutics, pharmaceuticals, and more to the crowd.

Houston-based Bairitone Health won the Michael E. DeBakey Memorial Life Science Award, established by BioHouston in honor of the groundbreaking Houston cardiovascular surgeon. The company is creating a wearable technology that takes a more innovative approach to sleep apnea and snoring with its SOMNAR platform that detects tissue-born sounds, identifies obstructions, and more. The award was presented by Ann Tanabe, CEO of BioHouston.

Ann Tanabe, CEO of BioHouston, presented the DeBakey Award to Houston-based Bairitone Health. Photo courtesy of Rice Alliance

For the first time, the event also named a people's choice award winner, as voted on by the audience members. Baritone Health also claimed the prize.

At the conclusion of the event, the Rice Alliance and BioHouston named the 10 most promising life science companies selected by investors and presented by the Greater Houston Partnership. This year's selection included the following companies, in alphabetical order.

Autonomize

Austin-based Autonomize unlocks data and context to enable human health outcomes

bEHR Health Systems

New Orleans-based bEHR Health Systems delivers, medical, lifestyle, and social solutions to health for African Americans.

EMPIRI

EMPIRI, based in Houston, is revolutionizing cancer care with a novel technology that accurately predicts each cancer patient's treatment responses empirically, enabling doctors to make the optimal treatment selection for each cancer patient.

InformAI

Houston-based InformAI develops AI-based medical image diagnostic tools and uses large dataset synthesis to develop clinical outcome predictors for physicians, hospitals, and medical imaging/medical device companies

March Biosciences 

Houston-based March Biosciences is impacting the most challenging lymphoma and leukemia.

MRG Health-SmartCare360

MRG Health-SmartCare360, based in Houston, is a determinate of health and disease specific virtual care management technology and services company that improves patient access to care and clinical outcomes for people suffering from one or more chronic disease.

Prana Thoracic

Prana Thoracic, founded in Houston out of JLABS at TMC, is a medical device startup that's innovating for the future of early intervention in lung cancer.

Steradian Technologies

Another med device startup based in Houston, Steradian Technologies employs deep-photonics technology to diagnose respiratory diseases in seconds, all for the price of a latte.

TYBR Health

Houston-based TYBR Health makes a hydrogel that protects tendons from scarring after surgery and improves patient outcomes.

Voythos

Voythos, based in Houston, is making medical records work for today's healthcare.

Check out these conferences, pitch competitions, networking, and more in the month of November. Photo via Getty Images

10+ can't-miss Houston business and innovation events for November

Where to be

Hold onto your hats, Houston. If you thought October was a busy month for business events, November even more exciting and full of pitches, conferences, summits, and more. Here's a rundown of what all to throw on your calendar for November when it comes to innovation-related events.

This article will be updated as more business and tech events are announced.

FEATURED: November 9 — Houston Innovation Awards Gala

Find out what Houston startups and innovators go home with the big win at InnovationMap and Houston Exponential's gala. Learn more about this year's finalists by clicking here.

The event is Wednesday, November 9, at 6 pm, at the Ion. Click here to register.

November 1-3 — Urban Manufacturing Alliance's Houston Gathering

Learn about the unique challenges and opportunities within manufacturing in the current economy, as well as network with Houston manufacturing professionals.

The event is Tuesday, November 1, to Wednesday, November 3, at West Houston Institute. Click here to register.

November 2 — Greentown Labs Climatetech Summit

Hear from the climatetech industry's leaders at Greentown Labs' annual event. The morning features panels and pitches, followed by lunch, networking, and an expo. The summit continues on November 3 in Boston, and both days will be streamed for viewers.

The event is Wednesday, November 2, at 8 am, at Greentown Houston and streaming online. Click here to register.

November 4 — Enventure's 10-Year Anniversary

Join Enventure as we celebrate its 10th Anniversary — from the organization's accomplishments to a look toward what the future brings to Enventure.

The event is Friday, November 4, at 7 pm, at III by Wolfgang Puck. Click here to register.

November 5 — Tech Fest Live in-person Experience at the Ion

The Ion as partnered with Tech Fest Live to bring your family to an engaging Family Tech Day experience, designed with middle and high school students in mind.

The event is Saturday, November 5, at 9:30 am, at the Ion. Click here to register.

November 8 — Texas Life Science Forum

The Texas Life Science Forum, co-hosted by BioHouston and Rice Alliance, is the premier life science and healthtech event in Texas that brings together members from industry, emerging life science companies, academic and investors. Hear pitches from innovative and early stage life science companies, network and enjoy exciting panels, keynotes and speakers.

The event is Tuesday, November 8, at 8:30 am, at Rice University. Click here to register.

November 9 — The Future of Industrial Automation Lunch & Learn with Yokogawa

In this Lunch & Learn, Elbert van der Bijl (Director of Marketing & Solutions Consulting for Yokogawa North America), will talk about the journey from industrial automation to industrial autonomy (IA2IA). He will also speak about how new technologies are being embraced to be able to make this transition. The presentation will highlight some key developments like Open Process Automation (OPA), Artificial Intelligence (AI) and Machine Learning (ML), and mobile Robotics and how they will play a role in the future of Industrial Automation.

The event is Wednesday, November 9, at 11:30 am, at The Cannon-West Houston. Click here to register.

November 10 — Greater Houston Partnership's State of the Port

Join the Greater Houston Partnership at the annual State of the Port featuring Ric Campo, Chairman of the Port Commission of the Port of Houston Authority. Campo will discuss innovations taking place at Port Houston and Project 11. The highly anticipated Project 11 will deepen and widen the Houston Ship Channel and increase economic impact, jobs and address supply chain challenges.

The event is Thursday, November 10, at 10:30 am, at The Omni Riverway. Click here to register.

November 10 — BGV Pitch Tour Houston

The BGV Pitch Tour is coming to Houston November 10th in partnership with Omaze and the aid of our amazing 6 Change Agents to throw a BGV Pitch Competition. Thee BGV Change Agents are amazing Black and/or Brown women-identifying founders who are actively working to uplift and grow the city's ecosystem for Black and Brown founders in their area.

The event is Thursday, November 10, at 6 pm, at The Cannon-West Houston. Click here to register.

November 15 — Lilie's Community Celebration

Celebrate the end of the semester and take a peek into what all the Liu Idea Lab for Innovation and Entrepreneurship community has going on.

The event is Tuesday, November 15, at 6 pm, at the Lilie offices at Rice University. Click here to register.

November 17 — Rice Alliance Clean Energy Accelerator 2022 Demo Day

Rice Alliance Clean Energy Accelerator is hosting a Demo Day to showcase its Class 2 startups who are ready for investment, pilots and accelerating the energy transition.

The event is Thursday, November 17, at 1:30 pm, at the Ion. Click here to register.

November 19 — Pearland Innovation Hub Pitch Competition

Come attend this event open to the community to hear pitches from local small business owners, network, and learn about the Pearland Innovation Hub.

The event is Tuesday, November 17, at 4 pm, at Pearland City Hall. Click here to register.

November 30 — Commercial ZEV Event

This event by Houston-based Evolve is your chance to drive zero-emissions commercial vehicles and learn how you can convert your fleet to save on costs.

The event is Wednesday, November 30, at 8:30 am to 5 pm, at NRG Park. Click here to register.

Here's which life science companies — in Houston and beyond — are ones to watch. Photo by Dwight C. Andrews/Greater Houston Convention and Visitors Bureau

Houston organization names 10 most promising life sciences startups

ones to watch

Last week, the Rice Alliance for Technology and Entrepreneurship gathered over 1,000 life science experts and attendees virtually for thought leadership as well as 40 company presentations.

The three-day 2020 Virtual Texas Life Science Forum was made possible through a partnership with BioHouston and support from Texas Medical Center and Insperity. At the close of the summit, several companies were recognized with awards.

Houston-based Starling Medical won the Michael E. DeBakey Memorial Life Science Award, established by BioHouston in honor of the groundbreaking Houston cardiovascular surgeon. The digital health device company is revolutionizing severe bladder dysfunction management with artificial intelligence.

Every year at the forum, the Rice Alliance names its 10 most promising companies working on developing innovative solutions in medical devices, digital health, diagnostics, pharmaceuticals, and therapeutics. This year, Brad Burke, managing director of the Rice Alliance, says they had more applications to present than ever before. Additionally, the presenting companies — about half of which are Houston-based — have already raised more than $275 million in funding.

The 2020 most-promising life science companies, which were chosen by investors and presented by the Greater Houston Partnership, were:

Droice Labs

Image via droicelabs.com

New York-based Droice Labs, is an artificial intelligence and big data company matches patients to therapies and delivers personalized medicine at scale while reducing costs.

"Our cutting-edge technology seamlessly integrates into clinical workflows, and we continue to evolve unique and powerful applications for our clients and the patients they serve," reads the company's website.

SFA Therapeutics

Image via sfatherapeutics.com

Based in Jenkintown, Pennsylvania, SFA Therapeutics is developing oral drugs for treating conditions of chronic inflammation that have the potential to change the practice of medicine. The company has treatments for Psoriasis, Liver Cancer (Hepatitis B, NASH and HCC), Ophthalmic Diseases, Cytokine Release Syndrome- a side effect in CAR-T, Prevention of Relapse/Recurrence in Leukemias, and other diseases.

Hummingbird Bioscience

Photo via jlabs.jnjinnovation.com

Hummingbird Bioscience, based in Houston's JLABS @ TMC, is tackling challenging targets that play a key role in disease yet have not been effectively drugged. The company has worked on 12 therapies in various stages of development, four of which have the potential to revolutionize their fields.

"At Hummingbird, we believe that modern approaches to systems biology and data science can overcome the challenges of classical methods of therapeutics discovery, and profoundly improve the way we deliver new transformative medicines," reads the company website.

CaseCTRL

Image via casectrl.com

Houston-based CaseCTRL is empowering surgeons with a management platform with software-as-a-service technology that uses AI and logistics to lower operational costs and simplify surgical planning.

"The surgical scheduling process is frustratingly stuck in the past: siloed, paper-based, and too dependent on single schedulers," reads the website. "Surgeons are stressed and overworked. They need a better way to communicate their complex surgical plans, timelines and resource needs."

Perimeter Medical

Image via perimetermed.com

Perimeter Medical, based in Dallas, is driven to transform cancer surgery with advanced, real-time, ultra high-resolution imaging tools including AI to address areas of unmet medical need.

"Perimeter is dedicated to providing solutions that drive better patient care and lower healthcare costs by providing critical information, during clinical procedures," reads the website.

Studio Bahria

Image via studiobahia.org

San Antonio-based Studio Bahia, is developing an accessible model for therapy in addressing mental health crises from the pandemic through virtual reality.

"We are in production of our first two therapies for release in the 4th quarter of 2020. Studio Bahia clients include corporate, retail, and institutional partners who purchase our headsets for $25 in providing mental health therapies and wellness tools to employees, executives, and patients," reads the company's website.

Tvardi Therapeutics

Photo via Getty Images

Tvardi Therapeutics, based in Houston, is a clinical-stage biopharmaceutical company focused on the development of a new class of breakthrough medicines for diverse cancers and chronic inflammatory and fibrotic diseases.

"Tvardi is focused on the development of orally delivered, small molecule inhibitors of STAT3, a key signaling molecule positioned at the intersection of many disease pathways," reads the website.

Koda Health

Image via kodahealthcare.com

Koda Health, Houston, uses AI to help guide difficult conversations in health care, starting with end-of-life care planning.

"You're entitled to protect the healthcare decisions that matter most to you and your family," the company's website promises. "Koda creates Care Plans to ensure that you get the medical care you want."

Immuno Genesis

Photo via Getty Images

Houston-based ImmunoGenesis is a clinical-stage biotechnology company developing therapeutics to catalyze effective immune responses in immunologically "cold" cancers such as prostate, colorectal, and pancreatic.

"Compared to existing immunotherapy drugs, we believe this antibody will both provide more consistent benefit for patients with immune-infiltrated tumors, and, for the first time, will also benefit patients with immune 'cold' cancers," says founder Dr. Michael A. Curran in a press release announcing the company's grant from the Cancer Prevention and Research Institute of Texas.

Ictero Medical

Image via Getty Images

Ictero Medical, based in Houston, is developing the first minimally invasive cryoablation solution to treat patients with gallstone disease. Ictero Medical has created a minimally invasive treatment, called The CholeSafe System, that uses cryoablation to defunctionize the gallbladder without having to remove it.

Log on to one of these informative online events happening throughout the rest of the month. Getty Images

10+ can't-miss virtual business and innovation events in Houston for November​

Where to be online

November is usually the last busy month for business events before the end of the year and ahead of the holidays, and this year — even though events have pivoted to virtual gatherings — is no different.

From panels and ask-me-anything meetings to summits and startup competitions, here are over 10 Houston innovation events you can attend virtually via online meetings. This month in particular there's the return of The Houston Innovation Summit and the brand new awards program called, The Listies (nominate now for those). Be sure to register in advance, as most will send an access link ahead of the events.

November 5 — Dell Technologies Ask Me Anything

Dell Technologies is hosting an "Ask Me Anything" session for the Ion community. During this time, attendees can ask experts anything in regards to IT pain points during these times. Entrepreneurs may also use this time to brainstorm the back end IT Infrastructure of their business.

The event will take place online on Thursday, November 5, at 10 am. Register here.

November 5-6 — Greentown Labs Climatetech Summit

Join Greentown Labs for its first Climatetech Summit for a deep dive into scaling climate action. Across the two days, attendees will engage with Greentown's pillars of climate action — technology, finance, policy, and justice — discover groundbreaking startups and their climatetech solutions, learn from industry experts, and forge meaningful connections with entrepreneurs, investors, business leaders, policymakers, startup support organizations, and other climate champions.

The event will take place online on Thursday, November 5, and Friday, November 6. Register here.

November 10 — Igniting Leadership: The State of COVID Vaccines

Join Ignite Healthcare Network for a special night of discussion hosted by IGNITE Steering Committee member Susan Feigin Harris about the status of COVID19 vaccine development with Dr. Maria Elena Bottazzi, Co-director of Texas Children's Center for Vaccine Development.

The event will take place online on Tuesday, November 10, at 6 pm. Register here.

November 10-12 — Texas Life Sciences Forum

The Texas Life Science Forum is the premier life science event in Texas that brings together members from industry, emerging life science companies, academic, and investors. The 2020 event will be virtual and will still be the "must attend" event for anyone in the life science industry in Texas or affiliated with innovation at the life science academic institutions. This event represents an opportunity to meet investors, learn about promising life science companies, to learn about opportunities for entrepreneurs, investment professionals, big pharma, academics and business executives serving the life science industry.

The event will take place online on Tuesday, November 10, to Thursday, November 12. Register here.

November 12 — Plaza Tec: Funding Fundamentals

Though Latinx-owned businesses and startups make up at least 38 percent of businesses in the Houston area, there is still a lack of access to capital blocking growth and progress for Latinx founders.

In this discussion presented by The Ion, representatives from baMa and NextSeed will join together to discuss angel investing and crowdfunding options for Latinx founders and what challenges one might face when seeking capital.

The event will take place online on Thursday, November 12, at 5:30 pm. Register here.

November 12 — Women in Tech and Biz

If you're interested in hearing from some badass women in tech and business, come to the virtual Women in Tech + Biz event created by the Liu Idea Lab for Innovation and Entrepreneurship. The event will be split into two sections — one focused on entrepreneurship and the other focusing more on software and engineering — followed by networking.

The event will take place online on Thursday, November 12, at 6 pm. Register here.

November 13 — Climathon 2020: Hacking Solutions to Houston’s Climate Challenges

On Earth Day this year, the City of Houston published its first Climate Action Plan. The plan is the culmination of thousands of volunteer time from industry professionals, policy stakeholders, and community advocates. Together the working groups have laid out a concise plan to address the climate challenges that Houston faces along with maintaining a leadership role in the energy transition. This year's Climathon will look to realize some of the goals of the plan through design sprints led by local subject matter experts in the areas of transportation, energy innovation, building optimization, and materials management.

The event will take place online on Friday, November 13, at 1 pm. Register here.

November 16-20 — The Houston Innovation Summit

The Houston Innovation Summit — THIS — celebrates Houston's innovation ecosystem during Global Entrepreneurship Week (GEW). THIS responds to 2020 with a special focus on the intersection of Impact and Innovation, spotlighting Houstonians at the forefront of education, ecosystems, inclusion, and policy. Join Impact Hub Houston and Houston's startup and small business community for a week of exciting programs and connect with the thinkers, doers, makers and innovators driving Houston forward.

The event will take place online on Monday, November 16, to Friday, November 20. Register here.

November 17 — Struggles and Bubbles: Pivoting during a Pandemic

Join General Assembly Houston to listen to a panel of startup founders who will share their journey and entrepreneurial struggles, and what it really takes to launch a startup during global pandemic, and scale a startup.

The event will take place online on Tuesday, November 17 at 5 pm. Register here.

November 17-19 — Capital Factory's Texas Startup Roadshow

For the first time, Capital Factory is taking its roadshow online. For three days, the organization will be introducing investors to the various innovative cities across the Lone Star State.

Houston will be the city of focus on Wednesday, November 18.

The event will take place online on Tuesday, November 17, to Thursday, November 19. Register here.

November 20 — The Listies

Let's toast to the entrepreneurial spirit of Houston in a time when celebrating victories is more important than ever. Introducing the Listies, brought to you Houston Exponential and InnovationMap, commemorating the launch of HTX TechList, Houston's innovation discovery platform.

The event will take place online on Friday, November 20, at 3 pm. Register here.

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CultureMap Emails are Awesome

Meet 6 mentors who are helping the Houston startup scene flourish

meet the finalists

Few founders launch successful startups alone — experienced and insightful mentors often play an integral role in helping the business and its founders thrive.

The Houston startup community is home to many mentors who are willing to lend an ear and share advice to help entrepreneurs meet their goals.

The Mentor of the Year category in our 2025 Houston Innovation Awards will honor an individual like this, who dedicates their time and expertise to guide and support budding entrepreneurs. The award is presented by Houston City College Northwest.

Below, meet the six finalists for the 2025 award. They support promising startups in the medical tech, digital health, clean energy and hardware sectors.

Then, join us at the Houston Innovation Awards this Thursday, Nov. 13 at Greentown Labs, when the winner will be unveiled. The event is just days away, so secure your seats now.

Anil Shetty, InformAI

Anil Shetty serves as president and chief medical officer for biotech company Ferronova and chief innovation officer for InformAI. He's mentored numerous medical device and digital health companies at seed or Series A, including Pathex, Neurostasis, Vivifi Medical and many others. He mentors through organizations like Capital Factory, TMC Biodesign, UT Venture Mentoring, UTMB Innovation and Rice's Global Medical Innovation program.

"Being a mentor means empowering early-stage innovators to shape, test, and refine their ideas with clarity and purpose," Shetty says. "I’m driven by the opportunity to help them think strategically and pivot early before resources are wasted. At this critical stage, most founders lack the financial means to bring on seasoned experts and often haven’t yet gained real-world exposure. Mentorship allows me to fill that gap, offering guidance that accelerates their learning curve and increases the chances of meaningful, sustainable impact."

Jason Ethier, EnergyTech Nexus

Jason Ethier is the founding partner of EnergyTech Nexus, through which he has mentored numerous startups and Innovation Awards finalists, including Geokiln, Energy AI Solutions, Capwell Services and Corrolytics. He founded Dynamo Micropower in 2011 and served as its president and CEO. He later co-founded Greentown Labs in Massachusetts and helped bring the accelerator to Houston.

"Being a mentor means using my experience to help founders see a clearer path to success. I’ve spent years navigating the ups and downs of building companies, struggling with cash flow, and making all the mistakes; mentoring gives me the chance to share those lessons and show entrepreneurs the shortcuts I wish I’d known earlier," Ethier says. "At Energytech Nexus, that role goes beyond just helping individual founders — it’s about creating a flywheel effect for Houston’s entire innovation ecosystem."

Jeremy Pitts, Activate Houston

Jeremy Pitts serves as managing director of Activate Houston, which launched in Houston last year. He was one of the founders of Greentown Labs in the Boston area and served in a leadership role for the organization between 2011 and 2015. Through Activate, he has mentored numerous impactful startups and Innovation Awards finalists, including Solidec, Coflux Purification, Bairitone Health, Newfound Materials, Deep Anchor Solutions and others.

"Being a mentor to me is very much about supporting the person in whatever they need. Oftentimes that means supporting the business—providing guidance and advice, feedback, introductions, etc," But just as important is recognizing the person and helping them with whatever challenges they are going through ... Sometimes they need a hype man to tell them how awesome they are and that they can go do whatever hard thing they need to do. Sometimes they just need an empathetic listener who can relate to how hard these things are. Being there for the person and supporting them on their journey is key to my mentorship style."

Joe Alapat, Liongard

Joe Alapat founded and serves as chief strategy officer at Houston software company Liongard and chief information officer at Empact IT, which he also owns. He mentors through Founder Fridays Houston Group, Software Day by Mercury Fund, SUPERGirls SHINE Foundation, Cup of Joey and at the Ion. He's worked with founders of FlowCare, STEAM OnDemand, Lokum and many other early stage startups.

"Being a mentor to me means unleashing an individual’s 10x—their purpose, their ikigai (a Japanese concept that speaks to a person’s reason for being)," Alapat says. "Mentoring founders in the Houston community of early stage, high-growth startups is an honor for me. I get to live vicariously through a founder’s vision of the future. Once they show me that compelling vision, I’m drawn to bring the future forward with them so the vision becomes reality with a sense of urgency."

Neal Dikeman, Energy Transition Ventures

Neal Dikeman serves as partner at early stage venture fund Energy Transition Ventures, executive in residence at Greentown Labs, and offices in and supports Rice Nexus at the Ion. He mentors startups, like Geokiln, personally. He also mentored Helix Earth through Greentown Labs. The company went on to win in the Smart Cities, Transportation & Sustainability contest at SXSW earlier this year. Dikeman has helped launch several successful startups himself, most recently serving on the board of directors for Resilient Power Systems, which was acquired by Eaton Corp for $150 million.

"Founders have to find their own path, and most founders need a safe space where they can discuss hard truths outside of being 'on' in sales mode with their team or board or investors, to let them be able to work on their business, not just in it," Dikeman says.

Nisha Desai, Intention

Nisha Desai serves as CEO of investment firm Intention and mentors through Greentown Labs, TEX-E, Open Minds, the Rice Alliance Clean Energy Accelerator, Avatar Innovations and The Greenhouse. She currently works with founders from Solidec, Deep Anchor Solutions, CLS Wind and several other local startups, several of which have been nominated for Innovation Awards this year. She's served a board member for Greentown Labs since 2021.

"When I first started mentoring, I viewed my role as someone who was supposed to prevent the founder from making bad decisions. Now, I see my role as a mentor as enabling the founder to develop their own decision-making capability," Desai says. "Sometimes that means giving them the space to make decisions that might be good, that might be bad, but that they can be accountable for. At the end of the day, being a mentor is like being granted a place on the founder's leadership development journey, and it's a privilege I'm grateful for."

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.

Rice, Houston Methodist developing soft 'sleep cap' for brain health research

Researchers and scientists at Rice University and Houston Methodist are developing a “sleep cap” that aims to protect the brain against dementia and other similar diseases by measuring and improving deep sleep.

The project is a collaboration between Rice University engineering professors Daniel Preston, Vanessa Sanchez and Behnaam Aazhang; and Houston Methodist neurologist Dr. Timea Hodics and Dr. Gavin Britz, director of the Houston Methodist Neurological Institute and chairman of the Department of Neurosurgery.

According to Rice, deep sleep is essential for clearing waste products from the brain and nightly “cleaning cycles” help remove toxic proteins. These toxic proteins, like amyloids, can accumulate during the day and are linked to Alzheimer’s disease and other neurological issues.

Aazhang, director of the Rice Neuroengineering Initiative, and his team are building a system that not only tracks the brain’s clearing process but can also stimulate it, improving natural mechanisms that protect against neurodegeneration.

Earlier proof-of-concept versions of the caps successfully demonstrated the promise of this approach; however, they were rigid and uncomfortable for sleep.

Preston and Sanchez will work to transform the design of the cap into a soft, lightweight, textile-based version to make sleep easier, while also allowing the caps to be customizable and tailored for each patient.

“One of the areas of expertise we have here at Rice is designing wearable devices from soft and flexible materials,” Preston, an assistant professor of mechanical engineering, said in a news release. “We’ve already shown this concept works in rigid device prototypes. Now we’re building a soft, breathable cap that people can comfortably wear while they sleep.”

Additionally, the research team is pursuing ways to adapt their technology to measure neuroinflammation and stimulate the brain’s natural plasticity. Neuroinflammation, or swelling in the brain, can be caused by injury, stroke, disease or lifestyle factors and is increasingly recognized as a driver of neurodegeneration, according to Rice.

“Our brain has an incredible ability to rewire itself,” Aazhang added in the release. “If we can harness that through technology, we can open new doors for treating not just dementia but also traumatic brain injury, stroke, Parkinson’s disease and more.”

The project represents Rice’s broader commitment to brain health research and its support for the Dementia Prevention Research Institute of Texas (DPRIT), which passed voter approval last week. The university also recently launched its Rice Brain Institute.

As part of the project, Houston Methodist will provide access to clinicians and patients for early trials, which include studies on patients who have suffered traumatic brain injury and stroke.

“We have entered an era in neuroscience that will result in transformational cures in diseases of the brain and spinal cord,” Britz said in the release. “DPRIT could make Texas the hub of these discoveries.”

Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.