This week's roundup of Houston innovators includes Samantha Lewis of Mercury, Lydia Davies of Teamates, and Karen Leal of Insperity. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from sportstech to venture capital — recently making headlines in Houston innovation.

Samantha Lewis, principal at Mercury Fund

Samantha Lewis, principal at Mercury Fund, joins this week's episode of the Houston Innovators Podcast. Photo courtesy of Mercury Fund

It's not an easy time to be a startup founder, and Samantha Lewis, principal at Houston-based venture capital firm Mercury, knows that best. She joined the Houston Innovators Podcast to share what she's observed from the market — and how to navigate these uncertain times.

“We all know it’s turbulent market times. We’re unsure where the market is going, and when there’s uncertainty in the public markets, that puts uncertainty in the private markets,” Lewis says on this week's episode of the Houston Innovators Podcast. “What I’ve been spending the past two quarters doing is working with our portfolio companies to just make sure our balance sheets are bulked up for what’s to come in 2023.” Read more.

Karen Leal, performance specialist at Insperity

Time to think ahead, business owners. Here's what this expert thinks you need to prioritize. Photo courtesy

It's that time of year — the time to plan ahead for the next calendar year. Karen Leal, an expert at HR solutions company Insperity, wrote in a guest column her tips for small businesses and startups navigating the current market and planning ahead.

"While it is uncertain what lies ahead for businesses in 2023, leaders can prepare to face staffing challenges by choosing the best talent and creating a culture that shows employees that they are valued," she writes. Read more.

Lydia Davies, founder of TeeMates Golf and Teamates

Calling all sports fans. Image via LinkedIn

Lydia Davies, who launched TeeMates Golf last year, is back with another way for the athletically inclined to find likeminded individuals. Teamates, a new, Houston-based, multi-sport meetup app, connects like-minded sporty types who want to connect and run, hike, surf, or play golf, pickleball, and more.

“I have noticed more and more over the years that it is hard for adults to find friends, especially to find friends to play sports with,” said Davies in a press release. “Why not get active and use it as an icebreaker? Let us come out of the last few years healthier and happier by linking together to get outside and get active. Teamates makes it so easy to join a meetup with just one click.” Read more.

Teamates, a new, Houston-based, multi-sport meetup app, connects like-minded sporty types who want to connect and run, hike, surf, or play golf, pickleball, and more. Photo courtesy of TeeMates

Smart new Houston-based app helps sporty locals connect and get their game on

play on

Active Houstonians who're looking to meet up with fellow locals and get their sports on now have a new app for that.

Teamates, a new, Houston-based, multi-sport meetup app, connects like-minded sporty types who want to connect and run, hike, surf, or play golf, pickleball, and more. Users can download the app on Apple IOS or Google Play.

Specifically, users follow their favorite sports, while the app then filters meetups and social feed for those sports. Users can join in, favorite friends, post meetups with photos, group message, request to join meetups, and post and share on the feed and stories.

Seriously competitive users can soon earn rewards and get on the leaderboard to win biweekly sports prizes. Friends can award others "Mate Medals" for being top-rated buddies and true MVPs.

Founder Lydia Davies created Teamates after launching TeeMates Golf last year. Her inspiration came out of necessity: Davis simply wanted to help her “golf-addicted husband” who travels frequently and was constantly playing rounds alone.

“I have noticed more and more over the years that it is hard for adults to find friends, especially to find friends to play sports with,” said Davies in a press release. “Why not get active and use it as an icebreaker? Let us come out of the last few years healthier and happier by linking together to get outside and get active. Teamates makes it so easy to join a meetup with just one click.”

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This article originally ran on CultureMap.

The Softeq Venture Studio has named 14 startups — two from Houston — to its third cohort. Photo via Getty Images

Houston tech company's venture studio names new partner and cohort

developing tech

A Houston-based tech company has named a new limited partner and 14 new startups to its venture arm.

Softeq Development Corporation announced its third group of early-stage startups to join the Softeq Venture Studio, which is geared at helping its resident startups quickly develop their technology and build their businesses. With 14 startups, the summer 2022 cohort is the largest yet and brings the total portfolio to 27 companies. Additionally, the $40 million Softeq Venture Fund welcomed Royal Eagle Capital Partners, a Houston-based investment firm, as a limited partner with its $3 million commitment.

“We are thrilled to see how much the Softeq Venture Studio has grown since 2021,” says Christopher A. Howard, founder and CEO of Softeq, in a news release. “We’re also pleased to welcome Royal Eagle Capital Partners as an investment partner in our Venture Fund, which allowed us to achieve more than 50 percent of our funding goal in just five months. We look forward to building on this partnership and growing Softeq in North America, Latin America, and beyond.”

Softeq is also celebrating a recent expansion into Latin America and staffing the new regional office with 30 engineers. The company has plans to grow to 150 employees in the region over the next year.

“The Softeq Venture Fund presents a unique opportunity to diversify our holdings within the alternative investments space. The concept of risk mitigation in venture investments resonates with investment firms globally, and we are excited to be working with Softeq and the amazing talent of their early-stage companies,” said Mark Valdez — co-founder, managing partner, and chief investment officer at Royal Eagle Capital Partners — in the release. "The emphasis on growth in Latin America by Softeq was a driving factor for our commitment and will open the door to new opportunities in Mexico and beyond.”

The Q2 2022 cohort is from across the United States with even some international representatives. The companies are using tech to solve problems across industries from human resources and wellness to med-tech and sports-tech and more. Applications are open for the next cohort online.

Here are the 14 companies making up the cohort:

  • Concerto Commerce, based in Southlake, Texas, is an eCommerce platform that combines automated catalog management and payment processing to streamline reseller operations.
  • New York City-based Dailyhuman is a software platform designed to help companies retain employees by fostering safety, trust, and connection in the workplace.
  • Headquartered in Houston, FrakBlock is a blockchain-based predictive tool providing financial products for the adulting process of young teens in Latin America.
  • High Tech Ranch Solutions, from The Woodlands, is a digital ranch management system designed by ranchers to bring monitoring to the palm of your hand.
  • Santa Barbara, California-based Homesavi is a platform that helps first-time homebuyers understand the home-buying process and guides them to their dream home.
  • Louder.ai is an advertising platform that revolutionizes how people can support causes they care about and see the impact of their donations.
  • Mallard Bay, founded out of Louisiana State University, is a marketplace for guided hunting and fishing trips that streamlines booking and administrative processes for consumers and outfitters. The company won Softeq's prize at the Rice Business Plan Competition.
  • RYN is a social platform to help families in the Middle East find and employ household migrant workers providing better working and living conditions.
  • Delaware-based SAmAS Gamify is building a gamified psychometric assessment platform that helps employers evaluate and select the most qualified candidates.
  • Founded in North Carolina, ShopAgain is an AI-powered customer retention platform redefining personalized customer experiences for eCommerce businesses.
  • Houston-based TeeMates Golf is a mobile app that connects golfers worldwide using social media, tee time linking, and offers a merchandise marketplace.
  • ViiT Health, based in Mexico, is a non-invasive technology to help people measure and monitor blood sugar levels more accurately without a finger prick lancet.
  • WellnessWins is a CRM to streamline intake processes for private therapy clinics to reduce waitlists and increase access to mental health care.
  • WorkHint helps retail companies manage on-demand hourly talent to increase flexibility, reduce cost, and generate actionable data-driven insights.
Swing into golf games with new friends with this new app. Photo courtesy of TeeMates Golf

New Houston-based golf app links up players, sets tee times, and more

there's an app for that

A new, Houston-based golf app is teeing up a chance for enthusiasts to link up over their love of the sport.

TeeMates Golf is a custom-made app that globally connects players and even sparks new networks and even friendships. The clever app has launched on the Apple Store and Google Play, with a full web version next month, the company notes in a press release.

How does it work? Users create a profile page with a (hopefully honest!) handicap, play preferences, description, and photos for sharing. Users can then post and share videos and photos on others' profile pages or on the newsfeed.

Players can review their favorite courses, show off swing skills, share best golf tips and drills, and more. Like most social media apps, users can like, comment, learn and interact from other people's lessons or posts, and also add friends, a release notes.

Game on
Those who already have scheduled a tee time and want to invite other players can utilize the "Create a Teetime" option. The feature searches for available players in the area, displays their profiles and skill level, and offers a chance to connect and invite to games. Like a dating app, users can even accept or decline — ouch — requests.

Another key feature allows players to post days and/or times they are available to play, which opens them up to an "add TeeMates" section. Available tee times also pop up in users' geographic areas.

Personal pro shop
TeeMates also boasts a pro shop feature, where users can create a store and sell their own new and used products (always a help for beginners who don't want to invest in expensive new clubs). Users can also promote their own clothing and apparel lines or gear.

The app was created by Houston realtor and self-professed sports enthusiast and tech lover Lydia Davies, who notes in press materials that her inspiration came from trying to assist her "golf-addicted husband" who travels frequently and was constantly playing rounds alone.

She added that her goal is to create an app that helps "grow and promote the game of golf by linking golfers globally in a social media setting. Whether it be for fun, competition, exercise, or just to meet new people with similar skill sets, TeeMates will serve as a network link for those that enjoy the sport."

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This article originally on on CultureMap.

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New 'living pharmacy' biotech company launches out of Rice venture studio

fighting cancer

Rice University’s biotech venture studio RBL LLC has launched a new “living pharmacy” company, Duracyte, designed to make cancer treatment easier on patients.

Backed by an up to $45 million Advanced Research Projects Agency for Health (ARPA-H) award, Duracyte aims to commercialize implantable biohybrid pharmacy devices that are designed to produce therapeutic proteins inside the human body around the clock, replacing the need for regular injections and infusions for some cancer patients.

The company’s main platform is its Hybrid Advanced Molecular Manufacturing Regulator (HAMMR), a rechargeable, implantable device that can sense biological signals, monitor tumor environments and adjust therapeutic output in real time. HAMMR has wireless communication capabilities, which allow patients and clinicians to remotely monitor results through an app every five minutes and make changes to treatment plans without a hosptial visit. Additionally, the device can generate its own oxygen supply, which is key for the therapeutic cells’ survival.

“Biologic medicines such as monoclonal antibodies, cytokines and metabolic regulators already account for a significant share of modern therapeutics, but the way we deliver them today often requires frequent injections or infusions that can be demanding for patients and lead to inconsistent drug levels,” Daniel Anderson, MIT professor and co-founder of Duracyte, said in a news release. “Our vision is to enable a continuous, stable therapy by producing these medicines directly inside the body, which could improve treatment consistency, reduce side effects and ultimately transform how biologic therapies are delivered across many diseases.”

Duracyte’s first clinical trial is slated to begin by the end of 2026 and will focus on recurrent ovarian cancer. The Phase I study will build upon existing work on encapsulated cytokine pharmacy technology, and the company hopes that within a few years this treatment can reach clinical application.

The development of Duracyte is supported by ARPA-H's Targeted Hybrid Oncotherapeutic Regulation (THOR) project, which supports a multidisciplinary research consortium co-led by Omid Veiseh, a professor of bioengineering at Rice. The consortium also includes others at Rice, The University of Texas MD Anderson Cancer Center, Stanford University, Carnegie Mellon University, Northwestern University and the University of Houston, plus industry collaborators like Chicago-based CellTrans.

“What we are building is the culmination of years of progress in cell engineering, biomaterials and implantable device technology,” Veiseh added in the release. “By combining these advances with real-time sensing and adaptive drug delivery, we are working with the support of RBL to create a true ‘living pharmacy’ that can deliver continuous, precisely controlled biologic therapies and fundamentally change how these treatments reach patients.”

RBL launched in 2024 and is based out of Houston’s Texas Medical Center Helix Park. Duracyte is the third company launched by RBL, including Sentinel BioTherapeutics, a clinical-stage immunotherapy company developing localized cytokine therapies for solid tumors, and SteerBio, a regenerative medicine company targeting lymphedema.

“Duracyte exemplifies the kind of breakthrough that Houston’s ecosystem is built to produce,” Paul Wotton, managing partner of RBL LLC and co-founder of Duracyte, added in the release. “With world-class clinical infrastructure, exceptional engineering talent and initiatives like the Texas Biotech Task Force driving alignment across industry, investment and talent, this region is uniquely positioned to move the most ambitious ideas in medicine from concept to patient, faster than anywhere else.”

Houston energy hub opens new fundraising cohort to fuel startups

Apply Now

EnergyTech Cypher has opened applications for its second Liftoff fundraising program.

Applications close May 20 for the 10-week virtual fundraising sprint. The program is geared toward energy and climatech founders preparing to raise their first institutional round. It will cover fundraising requisites, like pitch materials, term sheet negotiation and round closing, according to a release from EnergyTech Cypher.

The program kicks off June 1 and runs every Monday from 1-3 p.m. CST. It will conclude with an in-person capstone simulation in Houston on August 3, where founders will work to close a mock round.

Jason Ethier, EnergyTech Cypher founder and CEO, will lead the program with Payal Patel, an EnergyTech fellow and entrepreneur in residence.

The program is available through Cephyron, EnergyTech Cypher's new investor relationship management platform, built specifically for energy and climatech founders. Users must have a Cephyron Boost membership to participate in the Liftoff program.

The Cephyron IRM app recently went live and is available to founders at any point in their fundraising process, according to the news release. The platform aggregates investor data, tracks market signals and delivers curated weekly recommendations.

EnergyTech Cypher launched Liftoff last year. The inaugural cohort included 19 startups, including Houston-based AtmoSpark Technologies, The Woodlands-based Resollant and others. Each participant closed at least one fundraising deal, according to EnergyTech Cypher.

EnergyTech Cypher rebranded from EnergyTech Nexus earlier this year. It also launched its CoPilot accelerator in 2025. The inaugural group presented its first showcase during CERAWeek last month.

EnergyTech Cypher's annual Pilotathon Pilot Pitch and Showcase applications also opened this month. Find more information here.

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This article originally appeared on EnergyCaptialHTX.com.

Cancer diagnostics startup wins top prize at annual Rice competition​

winner, winners

Rice University student-founded companies took home a total of $115,000 in equity-free funding at the annual Liu Idea Lab for Innovation and Entrepreneurship's H. Albert Napier Rice Launch Challenge last week.

2025 Rice Innovation Fellow Alexandria Carter won the top prize and $50,000 for her startup Bionostic. The startup offers personalized diagnostics for cancer patients by using 3D culturing through its Advanced Tumor Landscape Analysis System (ATLAS) platform.

Carter is working toward her PhD in bioengineering in Professor Michael King's laboratory. She recently completed the Rice Innovation Fellows program and plans to commercialize ATLAS, according to a news release from Rice.

Actile Technologies, founded by another former Rice Innovation Fellow, Barclay Jumet, won second place and $25,000. The company is developing and commercializing textile-integrated technologies. InnovationMap first covered Jumet's wearable technology back in 2023.

Kairos took home the third-place prize and $15,000, plus the $2,000 audience choice award and the $5,000 undergraduate business award. Founded last year by Sanjana Kavula and Adhira Tippur, Kairos is an AI-powered patient intake platform built specifically for independent dental practices.

The NRLC features top startups founded by undergraduate, graduate and MBA students at Rice each year. The top three finishers were named among a group of five finalists earlier this year, which also included HAAST Autonomous and Project Kestrel.

HAAST is developing an unmanned aircraft for organ transport, while Kestrel uses machine learning to organize bird photographers’ photo collections.

Teams presented multiple five-minute pitches throughout the application process over Zoom and in-person before the five finalists presented at the NRLC Championships April 21 at the Rice Memorial Center. Each finalist walked away with an equity-free investment.


Other awards went to:

UnitCode

  • $5,000 MBA Venture Award

HAAST Autonomous

  • $2,500 Chan-Kang Family Prize for Bold Ambition
  • $1,000 Healthcare Innovations Prize

Telstar Networks

  • $2,500 Outstanding Undergraduate Startup Award

Multiplay

  • $1,500 Frank Liu Jr. Prize for Creative Innovation in Music, Fashion, & the Arts

Butterfly Books

  • $1,500 Social Impact Award

SOOZ

  • $1,000 Interdisciplinary Innovation Prize sponsored by OURI

Dooly

  • $1,000 Consumer Goods Prize

Project Kestrel

  • $1,000 AI Prize

Veloci Running won the NRLC last year for its naturally shaped running shoe. Founder and CEO Tyler Strothman recently told InnovationMap that the company has gone on to sell roughly 10,000 pairs of its flagship Ascent shoe, designed to relieve lower leg tightness and absorb impact. Read more here.