Houston ranked in the top emerging North American startup ecosystems

We're No. 4!

Houston fell on the international list of emerging startup hubs, but — when it comes to North America — Houston still ranks favorably. Photo via Getty Images

The evolution of Houston’s startup scene continues: A new report awards the region a No. 1 ranking for the robustness of early-stage funding among North America’s emerging startup ecosystems.

Policy advisory and research firm Startup Genome reports that startups in the Houston area attracted $884 billion in early-stage funding from the second half of 2020 to the end of 2022. Early-stage funding generally refers to a startup’s seed and series A rounds.

The $884 million figure puts Houston at No. 1 for early-stage funding among emerging startup ecosystems in North America and at No. 9 globally. Istanbul, Turkey, grabs the top global spot. Startup Genome characterizes the funding meccas in this ranking category as “Strong Starters.”

Startup Genome’s 2023 report on startup ecosystems emphasizes that early-stage funding “is an important indicator of potential success,” since most startups that receive series A rounds have demonstrated their potential by generating revenue, creating a minimal viable product, or being close to launching a product.

In Startup Genome’s global ranking of emerging startup ecosystems as a whole, Houston falls to No. 11 this year from No. 5 in 2022. The report doesn’t cite a reason for the drop. Copenhagen, Denmark, takes the No. 1 ranking in this category.

While its global ranking slipped, Houston still makes this year’s list of the top five emerging ecosystems in North America:

  1. Detroit (same position as last year)
  2. North Carolina’s Research Triangle (up two spots from last year)
  3. Minneapolis (down one spot from last year)
  4. Houston (down one spot from last year)
  5. Phoenix (up two spots from last year)

Startup Genome pegs the value of Houston’s startup ecosystem at $22 billion, based on startup exits and valuations from the second half of 2020 to the end of 2022.

A 2022 report from the Greater Houston Partnership noted that the Houston area is home to more than 60 organizations that foster startup growth. These include incubators, accelerators, coworking spaces, makerspaces, college and university programs, and nonprofit initiatives.

“These organizations have formed a growing web of resources assisting tech entrepreneurs across the Houston region,” says the report.

Silicon Valley once again tops Startup Genome’s list of the world’s leading startup ecosystems, followed by New York City and London (tied at No. 2), Los Angeles (No. 4), and Tel Aviv, Israel (No. 5).

Startup Genome defines a startup ecosystem as a shared pool of resources generally within a 60-mile radius of a central point, such as the city of Houston. These resources include accelerators, incubators, funding groups, coworking spaces, schools, and policymakers.

Startup Genome’s six ranking factors for ecosystems are performance, funding, talent and experience, market reach, knowledge, and “connectedness.”

“Despite current economic challenges, we are confident that, equipped with the right knowledge, entrepreneurs, policymakers, and community leaders everywhere can leverage opportunities to come together and show how innovative technologies can not only continue to drive growth and job creation, but simultaneously help save the planet and ensure a better future for everyone,” JF Gauthier, founder and CEO of Startup Genome, says in a news release. “This essential mission cannot be put on hold while we wait out rocky economic times.”

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Houston's ranking on this global report improved 14 spots between now and last year. Photo via Getty Images

Houston tech ecosystem ranks as No. 5 in the world for emerging startup hubs

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As a startup hub, Houston is movin’ on up.

In a new report from Startup Genome and the Global Entrepreneurship Network, Houston ranks fifth among the world’s top 100 emerging ecosystems for startups. Last year, the groups’ report put Houston at No. 19 in the same category.

Ahead of Houston on the list of the top emerging ecosystems for startups are first-ranked Detroit; second-ranked Hong Kong; third-ranked Dublin, Ireland; and fourth-ranked Minneapolis.

Further bolstering Houston’s status as a rising startup hub, Bayou City ranks third among the top North American challengers to traditional startup anchors like Silicon Valley, Boston, and Seattle. Joining Houston on the challengers’ list are first-ranked Detroit; second-ranked Minneapolis; third-ranked Research Triangle, North Carolina; and fifth-ranked Pittsburgh.

A recent report from Houston Exponential, which was recently acquired, emphasizes Houston’s position as the third fastest-growing tech ecosystem in the U.S. for early-stage startups. Houston sits behind Miami (No. 2) and Bridgeport-Stamford-Norwalk, Connecticut (No. 1).

Houston startups at all stages raised $2.34 billion in 2021, setting a record for the region’s annual VC haul, the HX report says. Of that total, early-stage startups collected $618.9 million in 46 deals.

Health and information technology startups dominate the VC landscape in Houston, with each accounting for 30 percent of VC deals in 2021, according to the HX report.

Elsewhere in Texas, Austin ranks 25th among the world’s top 100 ecosystems for startups, while Dallas ties for 31st place, according to the Startup Genome and Global Entrepreneurship Network report. San Antonio is wedged into the 91-to-100 range in the ranking of the world’s top 100 ecosystems.

“The importance and dispersal of tech startups have amplified the influence — for both good and ill — of geopolitics,” the report notes. “Where once the sector was sufficiently small to avoid the kind of pressures experienced by large industries such as energy and travel, those garage-spawned entrepreneurs have grown into a major economic force. Keeping their heads down is no longer an option.”

According to a new report, Houston is among the top emerging ecosystems. Photo by Zview/Getty Images

Houston rise in the ranks of the top emerging ecosystems in the world

stacking up

If you need evidence that Houston's startup ecosystem is flourishing, look no further than a new report from Startup Genome and the Global Entrepreneurship Network.

This year's Global Startup Ecosystem Report, released September 22, places Houston at No. 19 among the world's top 100 emerging startup ecosystems. Furthermore, it puts Houston at No. 4 among the top regional challengers in North America. Last year's report lumped Houston with other emerging startup ecosystems in the 31-to-40 ranking range.

Mumbai, India, appears at No. 1 among the world's top 100 emerging startup ecosystems this year, while Miami lands at No. 1 among the top regional challengers in North America.

According to Houston Exponential, the city's startup ecosystem "is experiencing a growth spurt that appears to show no signs of abating."

Case in point: Houston startups raised more than $1 billion in the first six months of 2021, surpassing all annual totals from previous years. In 2020, Houston startups reaped a record-high $753 million in venture capital.

"Venture capital invested in Houston startups has nearly quadrupled since 2016," according to a recent Houston Exponential report. "The sustained level of progress we've seen in startup formation and growth over the past four years shows that Houston has what it takes to build a vibrant, healthy innovation economy with an emphasis on equity."

Collectively, the health care and information technology sectors accounted for nearly 60 percent of Houston's VC deals in the first half of 2021, the report says.

Another sign of the expansion of Houston's startup ecosystem: the rising number of workspaces, incubators, and accelerators designed to foster startups.

"These key institutions create density and drive collisions among founders, investors, and talent, significantly increasing the rate of startup formation and growth," according to the Greater Houston Partnership.

Those institutions include The Ion entrepreneurial hub, the Greentown Labs climate-tech incubator, and the DivInc startup accelerator. All are new arrivals on the Houston startup scene.

"DivInc is about broadening the startup ecosystem by making it more authentically diverse, equitable, and inclusive of underrepresented entrepreneurs," Preston James II, CEO of DivInc, said in April. "When we, as a community, do this successfully, we optimize our opportunities for economic GDP growth, we can help reduce racial/gender wealth divide, and drive greater innovation."

Elsewhere in Texas, Austin ranks 20th among the leading startup ecosystems in the Global Startup Ecosystem Report, down from No. 19 last year, and Dallas repeats its 31st-place tie. Silicon Valley tops the global list.

The report says North America represents half of the top 30 ecosystems in the world.

"Entrepreneurs, policymakers, and community leaders in North America have been working hard to build inclusive innovation ecosystems that are engines of economic growth and job creation for all," JF Gauthier, founder and CEO of Startup Genome, says in a news release.

San Francisco-based Startup Genome is a research and advisory firm specializing in startup ecosystems.

A new hub on Rice University campus, Houston receives national rankings, and more local innovation news. Photo courtesy of Rice University

Shell commits to $10M carbon initiative with Rice University, Houston startup acquired by Honeywell, and more innovation news

Short Stories

Even toward the end of the year and amid the holiday season, Houston's innovation news can be a lot to keep up with. Here are seven short stories of Houston innovation — from an exit for a Houston startup and a multimillion-dollar clean energy commitment from Shell to new national recognitions for Houston and 2020 plans unveiled for MassChallenge in Houston.

Shell commits $10 million to new Carbon Hub at Rice University

Matteo Pasquali will lead the new hub at Rice University. Courtesy of Rice University

Rice University has introduced its Shell-backed Carbon Hub — a research initiative to innovate zero-emissions technologies. According to a news release, Shell has committed to a $10 million arrangement for the hub.

"Trying to address climate change is like playing whack-a-mole; you think you're making something better, and you realize that made something else get worse," says Carbon Hub director, Matteo Pasquali, in the release. "For example, you make cars more fuel efficient by removing weight, and then realize you've increased CO2 emissions by using more aluminum and carbon fibers. Or you try to fix CO2 into a useful product, and you realize you now need much more energy than you had gotten by making the CO2 in the first place."

The plan is to "fundamentally change how the world uses hydrocarbons," reads the release. Rather than burning hydrocarbons for fuel, creating carbon dioxide, the hydrocarbons "will be split to make clean-burning hydrogen fuel and solid carbon materials that can be used to make buildings, cars, clothing and more."

Through the partnership with Shell — and other potential partners — the hub will help fund and lead $100 million of science and engineering initiatives. The inaugural meeting for the hub is expected to be early next year and will be hosted by The Center for Energy Studies at Rice's Baker Institute for Public Policy.

"Providing energy to the world's population in an economically and environmentally sustainable manner is the global energy challenge," says Ken Medlock, senior director of the Center for Energy Studies, in the release. "In part, this will require new technologies and forward-looking, creative thinking, which is exactly what Carbon Hub offers."

Houston-based Rebellion Photonics acquired by Honeywell

Photo via rebellionphotonics.com

Innovative gas monitoring technology company, Rebellion Photonics, founded by Allison Sawyer and Robert Kester in Houston in 2009, has been acquired by Honeywell for an undisclosed amount.

The business will be rolled into Honeywell's Safety and Productivity Solutions business, as well as through Honeywell's Performance Materials and Technologies business, according to a press release.

"Honeywell is an amazing company and a recognized leader in our industry. We are excited to be part of their world-class family," Kester, who serves as CEO of Rebellion Photonics, says in the release. "Automated visual monitoring is the future of gas leak detection. Combining our products with Honeywell's platform will make this the new industry standard for safety and environmental monitoring globally."

MassChallenge to announce details of its second Houston cohort

Photo courtesy of MassChallenge

MassChallenge Texas has released new details of its second cohort in Houston. The zero equity startup accelerator based in downtown will run its second cohort from June to September of next year. Up to 100 startups will be selected for the Houston program, and another cohort of up to 100 startups will run along the same timeline in Austin.

On the line for prizes this year is six months of free office space, experts and mentors, the MassChallenge curriculum, access to top corporate leaders, as well as cash prizes and in-kind support — valued at over $500,000.

Both Austin and Houston will celebrate the launch of the two programs on January 29 — Houston's event will take place at the Four Seasons Hotel (1300 Lamar St.) from 5:30 to 7:30 pm.

MassChallenge recently announced its new home in The Cannon's Downtown Launch Pad in partnership with Amegy Bank.

Houston named in Inc.'s top 50 cities to start a business

houston skyline

Getty Images

Houston just made it onto the list of the top 50 cities to start a business, according to Surge Cities index, Inc., and Startup Genome. Coming in at No. 45, the Bayou City ranked behind Austin (No. 1) and Dallas (No. 29).

"Houston wants to be known as the Third Coast, a place that is both a business and cultural hub," the blurb on Inc. reads. "A place where people want to be. And this city, one of the most diverse in the country, is well on its way."

The report highlights Houston's historic hold on the oil and gas industry, the Texas Medical Center's established presence, and the space innovation happening at NASA. Roger Griesmeyer, a partner at Hunton Andrews Kurth, says in the article that Houston has low regulations and taxes coupled with "a highly educated populace, great weather, and a bunch of money."

"There's such diversity and a confluence of talent and opportunity in one place," says Griesmeyer in the article. "Houston is selling a lifestyle brand with all the resources to bear."

Houston was ranked highly on three factors:

  • No. 23 for job creation
  • No. 20 for wage growth
  • No. 25 for population growth

Accenture announces finalists for Houston-based competition

Courtesy of Accenture

In February, Accenture's Houston innovation hub will host the fourth annual Accenture HealthTech Innovation Challenge. Eleven companies have been named finalists and are headed to Houston in the new year.

"This annual HealthTech challenges creates an exciting opportunity to connect healthcare incumbents with emerging businesses to drive health system evolution focused on improving the lives of consumers and clinicians by enhancing access, affordability, quality and experience," says Brian Kalis, managing director of digital health and innovation services at Accenture, in the news release. "We are all looking forward to the final round and awards ceremony on February 6, 2020 in Houston when the finalists will present to an exclusive panel of healthcare executive judges."

No Texas companies were selected as finalists. The 11 selected startups are: New York-based Capital Rx, Minneapolis-based Carrot Health, San Francisco-based Cleo, Boston-based DynamiCare Health, San Francisco-based InsightRX, United Kingdom-based Lantum, Washington, D.C.-based Mira, Denver-based Orderly Health, New York City-based Paloma Health, St. Louis-based TCARE, and Seattle-based Xealth.

Houston area ranked the 18th best-paying city for software developers

Chart via heytutor.com

According to a new report from HeyTutor.com, the Houston-The Woodlands-Sugar Land metroplex is the 18th best-paying city for software developers. The report factored in salary and employment statistics for Houston and other U.S. metropolitan areas using data from the U.S. Bureau of Labor Statistics Occupational Employment Statistics.

Houston's mean adjusted software developer salary is $107,672 annually, according to the report. Here are some other interesting statistics regarding the Houston area from the data:

  • Mean software developer salary (adjusted): $107,672
  • Mean software developer salary (unadjusted): $109,503 — compared to $109,914 nationally
  • Mean salary across all occupations (unadjusted): $54,290 — compared to $51,960 nationally
  • Number of software developer jobs: 20,400 — compared to $51,960 nationally
  • Median home price: $205,600 — compared to $226,800 nationally

Business idea competition calls for applications

Photo courtesy of LILIE

The Liu Idea Lab for Innovation and Entrepreneurship has announced the applications for the 2020 H. Albert Napier Rice Launch Challenge business idea competition, which will take place on March 25. On the line is $60,000 in prize money to the teams, and the applications are open to Rice-affiliated teams until 11:59 pm on January 20.

To apply, click here.

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11 can't-miss Houston business and innovation events for August

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Editor's note: The tech event scene is heating up in August. From insightful talks to a young professionals summit, here's what not to miss and how to register. Please note: this article may be updated to include additional event listings.

Aug. 5 – Tech and Tequila Talk

Hear from guest speaker David Cohen, founder & CEO of Dallas-based Superposition, at the latest installment of Tech and Tequila Talk. The event will focus on breaking down ambiguity in data and AI projects through collaborative workshops.

This event takes place Tuesday, Aug. 5, from 5-7 p.m. at the Ion. Click here to register.

Aug. 11-16 – Black is Tech Week

Black is Tech Week will bring events for tech professionals, entrepreneurs and students to Houston through summits, career fairs, networking events and more. The event will feature speakers from Amazon, Microsoft, Google and many other companies.

This event begins Monday, Aug. 1. Find more information here.

Aug. 12 – NASA Stories at the Ion

Head to the Ion for the new morning series spotlighting the human side of space exploration. Each session will feature personal and powerful stories from astronauts and key NASA personnel. Anthony Vareha, NASA Flight Director and Flight Operations Directorate, whose primary duty is the safe operation of the International Space Station will speak this month.

This event begins Tuesday, Aug. 12, from 8:30-10 a.m. Find more information here.

Aug. 14 – Pickle Lab’s One-Year Anniversary Celebration

Enjoy an afternoon of open-play pickleball, beats by a live DJ, raffle giveaways and free swag at the first anniversary celebration of Pickle Lab in the Ion District. WonderPops will provide complimentary pops while supplies last, and Second Draught will serve each guest a free beverage.

This event takes place Thursday, Aug. 14, from 4-7 p.m. RSVP here.

Aug 19 – Navigating the Economy: Insights from Darren King

Darren King, chief investment officer of Moody Bank, will share his expert insights on the state of the economy and its impact on Houston’s future. Gain a deeper understanding of market trends, economic shifts and what they mean for businesses and individuals in the city.

This event takes place Tuesday, Aug. 19, from 11:30-1 p.m. RSVP here.

Aug. 21 – Transition on Tap

Greentown Labs’ signature networking event returns in August to foster conversations and connections within Houston's climate and energy transition ecosystem. Entrepreneurs, investors, students, philanthropists and more are invited to attend, meet colleagues, discuss solutions and engage with the growing community.

This event takes place Thursday, Aug. 21, at 5:30 p.m. at Greentown Labs. Click here to register.

Aug. 22 – Determined to Lead Women Lunch: Investing Through Market Cycles with Ellen Wilkirson

EnergyTech Nexus hosts a monthly Determined to Lead Women’s Lunch as part of its ongoing efforts to create safe spaces for women leaders in the energy transition to connect, learn and lead. The August session features Ellen Wilkirson, principal at Rev Innovations. With deep experience across traditional and transition energy sectors, Wilkirson will share how she’s approached investing through multiple market and commodity cycles and what it means to be a clean energy investor in today’s evolving landscape.

This event takes place Friday, Aug. 22, at 1 p.m. Click here to register.

Aug. 26 – Software Day at the Ion: Positioning your Startup to Capitalize on Market Trends

Software Day is a monthly series driving the support, inspiration and connections needed to help startups on their path to rapid, sustainable growth. Each month, Software Day will include office hours (by application), a keynote session and networking. This month’s panel discussion will feature Remington Tonar, co-founder of Cart.com, and Josh Teekell, founder of SmartAC.com.

This event takes place Tuesday, Aug. 26, from 3:30-7 p.m. Click here to register.

Aug. 27 – Future of Flight: Inside Venus Aerospace with Founder Sassie Duggleby

Join EO Houston for an exclusive, behind-the-scenes conversation with Sassie Duggleby, co-founder and CEO of Venus Aerospace, a Houston-based company pioneering breakthrough propulsion systems for hypersonic and space applications.

This event takes place Wednesday, Aug. 27, at 10 a.m. at Venus Aerospace. It is open to EO members and partners only. Click here to register.

Aug. 27 – The Future of American Science: A Conversation With US Rep. Brian Babin

U.S. Rep. Dr. Brian Babin and Paul Cherukuri, vice president of innovation at Rice University, will discuss how the United States remains at the forefront of space exploration, emerging technologies and scientific advancement, as well as what's next and what's at stake for the future of science policy.

This event takes place Wednesday, Aug. 27, from 3-4 p.m. at James A. Baker III Hall on Rice University's campus. Click here to register.

Aug. 28 – HYPE Summit

The third annual Houston Young Professionals and Entrepreneurs (HYPE) Summit is a day-long conference featuring panel discussions with business and thought leaders, workshop-style breakout sessions and networking opportunities. This year's event—under the theme Step Into the Spotlight—will feature speakers from First Bight Ventures, Bot Auto, Regions Bank, Lopez Negrete Communications and Umbrage.

This event takes place Thursday, Aug. 28, from 8:30 a.m.-5:30 p.m. at The Hobby Center for the Performing Arts. Click here to register.

Houston's 13 best midsize companies and more innovation news to know

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Editor's note: The top innovation news from the second half of the month includes new leaders at innovative Houston organizations and a ranking of the best midsize businesses from Time. Here are the five most-read InnovationMap stories from July 15-31, 2025:

13 Houston businesses appear on Time's best midsize companies of 2025

13 Houston-area businesses ranked on Time magazine's best midsize companies list. Photo via Getty Images

Houston-based engineering firm KBR tops the list of Texas businesses that appear on Time magazine and Statista’s new ranking of the country’s best midsize companies. KBR holds down the No. 30 spot, earning a score of 91.53 out of 100. Twelve other Houston-based companies landed on the list. Continue reading.

Digital Health Institute's new exec director aims to lead innovation and commercialization efforts

Pothik Chatterjee was named executive director of Rice University's and Houston Methodist's Digital Health Institute, effective May 1. Photo courtesy Rice University.

Though our existences have become deeply entangled with technology, our health has been slower to catch up. The creation late last year of the Digital Health Institute was a major step into the future for both Rice University and Houston Methodist, for whom the institute is a joint venture. The latest news for the Digital Health Institute is the appointment of Pothik Chatterjee to the role of executive director. Continue reading.

Houston hardtech accelerator names 8 scientists to 2025 cohort

Activate Houston has named eight fellows to its 2025 cohort. Photo courtesy the Ion.

National hardtech-focused organization Activate has named its 2025 cohort of scientists, which includes new members to Activate Houston. The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California, where Activate is headquartered. Collectively, the 2025 Activate Fellowship consists of 47 scientists and engineers from nine U.S. states. Continue reading.

Rice biotech accelerator appoints 2 leading researchers to team

The Rice Biotech Launch Pad has named two bioengineering professors to its leadership team. Photo courtesy Rice University.

The Rice Biotech Launch Pad, which is focused on expediting the translation of Rice University’s health and medical technology discoveries into cures, has named Amanda Nash and Kelsey L. Swingle to its leadership team. Both are assistant professors in Rice’s Department of Bioengineering and will bring “valuable perspective” to the Houston-based accelerator. Continue reading.

Innovation Labs @ TMC set to launch for early-stage life science startups

Innovation Labs @ TMC will open next year at the TMC Innovation Factory. Photo courtesy JLABS.

The Texas Medical Center will launch its new Innovation Labs @ TMC in January 2026 to better support life science startups working within the innovation hub. The 34,000-square-foot space, located in the TMC Innovation Factory will feature labs and life science offices and will be managed by TMC. Continue reading.

Intuitive Machines lands $9.8M to complete orbital transfer vehicle

space funding

Houston-based Intuitive Machines, which rang the NASDAQ opening bell July 31, has secured a $9.8 million Phase Two government contract for its orbital transfer vehicle.

The contract will push the project through its Critical Design Review phase, which is the final engineering milestone before manufacturing can begin, according to a news release from the company.

Intuitive Machine's orbital transfer vehicle (OTV) is designed to transfer payloads between Earth's orbit and the Moon and is built around the company's Nova-C lander, which has been a part of two successful lunar missions.

“Our OTV is a direct evolution of our lunar surface delivery missions—positioning us to expand into the rapidly growing market for in-space logistics,” Steve Altemus, Intuitive Machines CEO, said in the release. “We’re leveraging our flight-proven technology to operate a mission-ready service that delivers customer payloads across orbits—from Earth to the Moon and beyond.”

The company says the fast, flexible vehicle could be used for orbital servicing, logistics and communications in medium earth orbit, low lunar orbit and a variety of other destinations.

Intuitive Machines expects to begin manufacturing and flight integration as soon as 2026, once the design review is completed.

The non-NASA contract is for an undisclosed government customer, which Intuitive Machines says reinforces its "strategic move to diversify its customer base and deliver orbital capabilities that span commercial, civil, and national security space operations."

The company has received millions from NASA for its lunar rover, lunar lander, science and technology payloads, and communications and navigation services over the years. It also recently landed up to $10 million to help develop an Earth re-entry vehicle and in-space biomanufacturing lab from Texas's Space Exploration and Research Fund.

Earlier this month, the City of Houston agreed to add three acres of commercial space for Intuitive Machines at the Houston Spaceport at Ellington Airport. Read more here.

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