3 Houston companies rank among best in biz list

better than all the rest

Inc. magazine's 2022 Best in Business list recognizes influential and impactful companies. Photo via Getty Images

In the season’s spirit of giving, Inc. magazine has named three Houston companies to its 2022 Best in Business list, recognizing companies that put purpose before profit.

The Houston honorees are:

  • Enchanted Rock, a producer of energy microgrids powered by natural gas and renewable natural gas. In a news release, Thomas McAndrew, the company’s founder and CEO, says the Inc. recognition reflects “the dedication and hard work of our employees who work tirelessly to help our customers keep their power on.”
  • Proxima Clinical Research, a contract research organization for the biotech and medtech sectors. Earlier this year, Proxima appeared on the Inc. 5000 list of the country’s fastest-growing private companies.
  • Smith, a distributor of electronic components and semiconductors. The company has undertaken several humanitarian relief efforts for Ukraine, including the donation of at least $750,000 worth of electronics to Ukrainian citizens.

Inc. says its Best in Business list recognizes “the most dynamic companies of all sizes and industries that have had an outstanding influence on their communities, their industries, the environment, or society as a whole.”

Rather than relying on criteria tied to sales or funding, Inc.’s editors reviewed companies’ achievements over the past year and focused on how they made a positive difference in the world. They then selected honorees in 55 overall categories, and in age-based, revenue-based, size-based, and impact-based categories.

In all, Inc. named 14 Texas companies to this year’s Best in Business list. Aside from the three Houston companies, they are:

  • Austin-based AlertMedia, which produces emergency communication software
  • Austin-based Halcyon, a provider of security technology
  • Austin-based Matterlab, a communications agency
  • Austin-based Pushnami, which offers an advertising and engagement platform
  • Austin-based ZenBusiness, a provider of business products and services
  • Dallas-based Upkeep Aesthetics, a franchiser of medical spas
  • Fort Worth-based TimelyMD, which delivers virtual health and well-being services for students
  • Frisco-based Lexipol, a provider of policy, training, and wellness services for the public safety sector
  • Irving-based Tricolor Holdings, which sells used cars and extends auto loans to underserved Hispanic consumers
  • Plano-based Improving, a provider of tech consulting and training
  • San Antonio-based AmeriVet Veterinary Partners, an operator of veterinary practices
This week's Houston innovators to know includes Tudor Palaghita of Camppedia, Robert Kester of Honeywell, and Ed Wooten of Smith. Photos courtesy

3 Houston innovators to know this week

who's who

This week's Houston innovators to know are all using technology — but in completely different ways and across various sectors.

From creating a circular and sustainable economy for your company's technology to an online platform for your child's various activities — and even a socially distant way of checking temperatures — here is this week's who's who of Houston innovation.

Tudor Palaghita, CEO and founder of Camppedia

Tudor Palaghita has advanced his startup, Camppedia, so that parents can have virtual and in-person activities for their kids this summer. Photo courtesy of Camppedia

Like most of the world, Tudor Palaghita's year isn't going as planned. The founder of Camppedia — an online marketplace and tool for parents finding and managing their kids' activities — was hoping this summer was going to be his company's break-out moment and proof of concept. Instead, he's had to act quickly and pivot to focus on community and virtual opportunities.

"If anything, the pandemic forced us to move a lot of things forward," Palaghita says on the recent episode of the Houston Innovators Podcast. "The focus on the community was also something coming earlier than planned, but it was the most wonderful thing to come out of this. It really feels like everybody came together to give and to help each other."

Camppedia's business model is to give local camp and program providers — mostly small businesses, Palaghita says — a place to seamlessly reach parents. Now, these providers need Camppedia's platform more than ever as parents seek options a as they return to work or continue to look for at-home entertainment for their kids. Click here to read more.

Robert Kester, founder of Rebellion Photonics and president and general manager at Honeywell

Robert Kester found a new use for his temperature monitoring tech he created for the oil and gas industry. Photo courtesy of Honeywell

As the pandemic began to spread across the country, Robert Kester saw an opportunity for his technology he built for the oil and gas industry. Kester founded Rebellion Photonics, which Honeywell acquired in December of last year, and the company's ThermoRebellion temperature software uses infrared imaging technology and artificial intelligence to quickly conduct non-invasive screenings of people before they enter offices, banks, airports, as businesses begin to reopen.

"The key component is our software powered by artificial intelligence," Kester tells InnovationMap. "Our imaging systems leverage a decade of experience in the most advanced imaging technologies for gas leak detection, fire detection, and intrusion monitoring applications. The system features uncooled high-resolution FPA infrared sensors allowing for each pixel to be assessed for temperature."

By Kester's and his team's estimates, the ThermoRebllion system will be ready to deploy as early as June. Click here to read more.

Ed Wooten, director of IT asset disposition at Smith

Building a circular economy for electronics requires attention to detail in the areas of design, buyback, or return systems, advanced recycling and recapturing, durability and repair, and urban mining, writes Ed Wooten. Photo courtesy of Smith

For 20 years, Ed Wooten has worked to help clients figure out how to navigate the processes of buyback, recycling, and repair in order to create sustainable and profitable solutions to reduce e-waste.

"The world produces 40 million tons of e-waste annually, and only 20 percent of that is being disposed of properly," Wooten writes in a guest column for InnovationMap. "A circular economy is a system in which all materials and components are kept at their highest value and where e-waste is essentially designed out of the system."

Wooten gives his advice for creating a circular economy. Click here to read more.

Building a circular economy for electronics requires attention to detail in the areas of design, buyback, or return systems, advanced recycling and recapturing, durability and repair, and urban mining. Christina Morillo/Pexels

Houston expert shares tip for developing a circular economy within your company's tech

Guest column

Many organizations are interested in building a circular economy into their business model but aren't sure what steps to take to achieve this goal. I've worked in the technology industry for over 20 years, helping customers across all industries navigate the processes of buyback, recycling, and repair in order to create sustainable and profitable solutions to reduce e-waste.

The world produces 40 million tons of e-waste annually, and only 20 percent of that is being disposed of properly. A circular economy is a system in which all materials and components are kept at their highest value and where e-waste is essentially designed out of the system.

Building a circular economy for electronics requires attention to detail in the areas of design, buyback, or return systems, advanced recycling and recapturing, durability and repair, and urban mining.

Below, I'll discuss some key building blocks for implementing an effective and efficient circular economy.

Invest in technology that will last

Longevity is essential to maintaining sustainable products, and that is easily achievable through repair and refurbishment services. Upgrading or reworking existing equipment can save you time and money by enhancing its marketability or extending its useful life.

Rework service providers can replace components inside servers or PCs and rebuild them with new parts to meet your requirements. These services can boost your operations' speed or improve your servers' or PCs' performance through upgrading, while also saving your organization money by not having to purchase all-new equipment.

Recover value through the secondary market

When equipment must be replaced or retired, many electronic devices can be remarketed, either as whole products or individual parts. This system not only keeps electronics in use and out of landfills — it can also serve as an additional revenue stream for your organization.

Finding the right IT asset disposition partner is crucial for maximizing your return on investment. It can pay dividends to provide high-exposure opportunities to a vast network of customers through a mix of online sales, e-commerce tools, and inside sales when selling your retired equipment.

Utilize advanced recycling and recapturing programs

Retired electronics that are not remarketable can be collected and have their components reintegrated into new products, creating a closed-loop production system. ITAD partners who are certified to recognized green standards, such as R2 or e-Stewards, can ensure that IT equipment that no longer has value will be responsibly recycled.

No matter what industry you're in, a qualified ITAD partner can help optimize your organization and support your goals. From data centers to server rooms and beyond, sustainable solutions are available to manage the equipment you need to retire in compliance with all regulatory guidelines.

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Ed Wooten is Smith's director of ITAD, or IT asset disposition.

Coronavirus likely will affect your supply chain — here's what to keep in mind. Getty Images

Houston expert: Here are 3 tips for a resilient supply chain during the coronavirus outbreak

Guest column

Consumers rarely consider the intricacies of managing a cohesive supply chain when the process needed to deliver product to market is free of disruptors. In short, engineering and design work is completed, a bill of materials is established, material is sourced, and product is manufactured.

Manufacturers often expect to easily purchase product off the shelves or online. When external factors come into play that have the potential to disrupt supply chains and the quick availability of product, proper management is even more critical for businesses and their customers.

During my 23 years at Smith, the world's largest open-market distributor of electronic components, I've witnessed various market disruptions and shifting supply chain dynamics. I can confidently say that the coronavirus outbreak is heavily uncharted territory for the technology industry. Mitigating supply chain disruptions during troubling times, however, is familiar to us. Even through uncertainty, I want companies to know that there are many options to keep their supply chains active.

Here are my top three tips for properly managing your supply chain during the coronavirus outbreak:

Assess inventory levels and run outages scenarios

It is important to not only assess your on-hand inventory levels but to quickly gauge the impact and availability of product from key suppliers. As a precaution and to prevent further spread of the virus, many electronic component manufacturing plants in China were shut down for weeks, and some are still running at limited capacity with prominent labor shortages.

Finding out which manufacturers have been shut down or are affected by the virus will help determine lead times and availability requirements. Surveying suppliers is an efficient way to gauge manufacturers' levels of impact and determine your own needs. Bear in mind what possible logistics delays you may encounter when assessing your material levels.

Build contingency plans with alternative sources.

With supply constraints from traditional sources being almost an inevitability, having flexible sourcing options and relationships with key suppliers is a prime strategy for contingency planning.

On top of that, make sure your sourcing partner has put stringent quality procedures in place and is certified to the highest industry standards. Expanding your AVL (approved vendor list) and qualifying other manufacturers will help keep lines running according to forecast.

Ensuring heightened supplier screenings with end-to-end evaluation transparency is even more essential during times of disruption. Trusted, multichannel sourcing capabilities are prime options in the face of the consistently evolving global situation.

Stay vigilant, and work closely with your emergency response team.

Uncertainty will continue to play a major role throughout the outbreak situation. From my experience, staying up to date with the latest news and maintaining frequent communication with both internal and external parties is one of the most proactive approaches to disruptive situations.

Smith's shipping and logistics hubs have mirrored capabilities and are located in Houston, Hong Kong, and Amsterdam, so we have been able to keep our operations running throughout the outbreak. Although Smith's business operations have continued without any shutdowns, the electronics supply chain has been significantly impacted, and disruptions will be felt for some time. The effects of the coronavirus are expected to trickle down to end consumers, as new product introductions for some consumer electronics have been delayed. Reports are even indicating that the supply and availability of technology products during the peak holiday season may be disrupted.

With the millions of components that go into everything from consumer electronics to oil and gas and medical equipment, our industry could see notable shortages in supply throughout the year. I encourage all companies and especially our friends here in Houston to thoroughly evaluate their supply chains. Utilizing these tips to implement a resilient supply chain will help build a strategic business outlook.

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Todd Burke is president at Houston-based Smith and Associates.

Accenture and Plug and Play Tech Center made strategic hires in Houston. Plus, a local expert shares how important electronics recycling is. Courtesy photos

3 Houston innovators to know this week

Who's who

The movers and shakers of the Houston innovation world did a lot of extra moving and shaking last week. This week's Houston innovators to know include two new hires within the ecosystem.

Thomas Rubenak, senior principal at Accenture Ventures

Thomas Rubenak is senior principal of Accenture Ventures. Courtesy of Accenture

Thomas Rubenak has watched Houston's startup scene blossom over his career. Now, as senior principal at Accenture Ventures, he gets to help startups connect with Accenture and its clients.

"It's a win-win-win," Rubenak tells InnovationMap. "The client gets the benefit of having the best of the best and the startups get amazing exposure to companies they might not have been able to get in front of. And, Accenture is happy because it gets to serve the client." Read more about Rubenak and his new gig at Accenture.

Payal Patel, director of corporate relations at Plug and Play

Payal Patel, former director of business development at Station Houston, has joined Plug and Play as director of corporate partnerships. Courtesy of Payal Patel

Plug and Play Tech Center has made its first Houston hire. Payal Patel, who was preciously the director of business development at Station Houston, is now the director of corporate partnerships at Plug and Play.

"As I've gotten to know Plug and Play, what I've been most impressed with is the resources and capabilities they have," Patel says. "They've got great Fortune 500 corporate partners, they work and know the best tech startups all over the world, and they have a strong investment capability. I'm excited that those resources and capabilities are coming to Houston." Read more about the new hire and Plug and Play's plans for Houston.

Ed Wooten, director of ITAD at Smith

Wooten oversees IT asset disposition for Smith. Courtesy of Smith

Ed Wooten is in the business of safe, efficient, and responsible electronics disposal. In a world with cybersecurity threats around every corner, making sure your devices are responsibly disposed of is so important. Wooten wrote a guest article for InnovationMap about some of the lesser-known aspects regarding IT asset disposition.

"I've worked in the technology industry for over 20 years, helping customers across all industries ensure the proper and secure disposal of their equipment," writes Wooten. "I specifically want Houston businesses to be aware of some of the less-obvious facts when it comes to electronics recycling and disposal — and for them to know that trusted, locally based IT asset disposition (ITAD) services are available." Read more of Wooten's piece here.

Here's what you need to know before you toss out your old computers. Walter Zerla/Getty Images

5 things to know before you get rid of your company's old electronics

Guest column

It's important for all companies to take certain factors into consideration before they get rid of their excess electronics. I've worked in the technology industry for over 20 years, helping customers across all industries ensure the proper and secure disposal of their equipment. I specifically want Houston businesses to be aware of some of the less-obvious facts when it comes to electronics recycling and disposal — and for them to know that trusted, locally based IT asset disposition (ITAD) services are available.

The world produces 40 million tons of e-waste annually, and only 20 percent of that is being disposed of properly.

Electronic waste and its environmental effects are a serious global issue. When businesses go through technology refreshes, much of their equipment ends up sitting in landfills; this can be avoided, though. Like other widely used materials, such as glass, paper, and plastic, excess electronics and their parts can be recycled, too.

Law firms, health centers, financial institutions, and many other types of businesses aren't necessarily expected to break down electronics and recycle pieces themselves. All businesses, though, are obligated to work with a trusted IT asset disposition partner when disposing of or replacing electronic equipment to ensure that best practices for removal are followed.

Recycling and disposal experience matter when it comes to ensuring compliance with federal and environmental laws. 

Major countries around the globe, including the United States, have implemented strict recycling laws. Especially in recent years, the federal government has placed a heavy emphasis on proper electronics disposal practices. New tech products and their upgraded versions are released constantly, replacing older equipment with the latest and greatest.

For businesses, technology refreshes are often large-scale, requiring a major equipment overhaul. When mass amounts of products are left to contend with, it's easy (and common) to overlook key details. It is important to note that some environmental laws will vary by state and even by city ordinance.

Companies should partner with an ITAD professional that prioritizes reliability and is certified to a recognized, international recycling standard. e-Stewards certification offers a great example of globally responsible recycling practices that operate in accordance with specific laws. The right ITAD partner can help companies protect their overall brand integrity while staying in compliance with recycling laws.

The only way to ensure that sensitive information is safely eliminated is to wipe or shred drives.   

The rise of data breaches in the U.S. — both small and large — is concerning. Breaches often take place because hardware is handled improperly. Technology refreshes are very common, usually occurring about every two to five years for businesses.

Across office spaces, millions of megabytes of data are stored on employees' equipment. All devices, from PCs to desk phones, house potentially sensitive company information. The drives in computers are usually most at risk for compromising data. Fortunately, data can be safely removed by wiping information off the hardware or shredding it to unrestorable size.

Value can be recovered from excess electronics. 

Depending on the equipment and hardware specifications, some electronics can be remarketed as whole products or sold for their individual parts. Excess electronics are often resold at a small percentage of their original purchase price, though. But, when monetary value can be recovered from parts, companies can invest recouped revenues into new equipment.

The secondary market for excess IT equipment is quite large. Partnering with an ITAD professional that has the right network and connections can help customers achieve maximum return on investment for their equipment.

Local, on-site disposal solutions are conveniently available.  

Proper electronics recycling is easy when you partner with a trusted, experienced IT asset disposition professional. Instead of having product shipped to warehouses, companies can elect for disposal solutions to come to them. Shred trucks can wipe and destroy data off of about a thousand hard drives or SSDs per hour.

Serving as an extension of an ITAD professional's warehouse, shred trucks offer the same quality of services, but are fully mobile. On-site data sanitization services, complete with certificates of wiping and destruction, can be included. A company's IT equipment can be securely removed and documented without ever having to leave its premises.

As a facilities manager, IT supervisor, CTO, or CIO, if you don't already have a technology recycling program in place, you should start assessing your needs. If you do have an IT asset disposition program in place, make sure your partner is thoroughly qualified. The five disposal facts I've listed should serve as a guidepost for industry best practices.

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Ed Wooten is Smith's director of ITAD, or IT asset disposition.

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What to expect from the inaugural TiECon Texas event this week

where to be

Innovators and entrepreneurs will gather in Houston this week to show off their latest advancements in automation during the first-ever TiECon Texas conference at the Ion District.

“Automation is not simply changing how we work. It is redefining how value is created across every industry,” Somesh Singh, president of TiE Houston, said in a release. “Texas has the talent, the infrastructure, and the entrepreneurial spirit to lead this transformation. TiEcon Texas 2026 is where the people building that future will come together to shape it."

The Indus Entrepreneurs (TiE) started in Silicon Valley in 1994 as a two-day seminar, but has grown into a worldwide network of events celebrating technological advancement. TiECon in Houston is a merger of the TiE networks across Texas for one large-scale event taking place at the Ion on Wednesday, October 28, and Thursday, October 29. Tickets are available here.

The event includes a partnership with Hatch Pitch, a founder-first startup showcase that has raised over $20 billion in funding for new companies in the tech industry. Participants will come from industries like space exploration, healthcare, energy, and the AI sector to present their ideas in front of an investor network for possible development.

“Over 80 percent of the teams we have coached have gone on to receive funding,” Greg Wright, founder of Hatch Pitch, added in a release.

In addition, there will be forums and talks on a variety of automation subjects, everything from robotic surgery to automation in government. Educators from Baylor College of Medicine, UTHealth Houston, and the University of Houston plan to discuss the raising of children in a world with extensive artificial intelligence integrated into so many areas. Steven Kean, President and CEO of the Greater Houston Partnership, will give the keynote speech on the Bayou City’s place in these emerging technological spheres.

Singh highlighted how the large-scale disruptions in the technological status quo by the rise of AI could be a sign of potential growth and innovation. The entrepreneurs presenting at TiECon may be the ones to harness the sometimes unsteady AI industry for good causes.

“History shows that periods of technological disruption create extraordinary opportunities for those prepared to act,” he said. “TiEcon Texas is designed to help founders, investors, and enterprises understand where the automation economy is headed and how to participate in building it."

Here are the 10 startups pitching during the TiE Hatch Pitch competition:

Houston startup makes Time's list of the best inventions of 2026

Innovation Station

One of the year's most buzzworthy innovations comes from a Houston-based leader in the energy transition. Utility Global's H2Gen recently made Time magazine’s list of the 300 best inventions of 2026.

The H2Gen is an innovative system that produces low-cost clean hydrogen from water and industrial off-gases. The company says the process doesn’t require electricity, a notable claim since hydrogen production typically consumes a lot of power.

"Using a tubular electrochemical cell containing a proprietary electrolyte and water, the company can turn industrial off-gases into hydrogen at scale—no extra electricity required," writes Time. "Bonus: the process also pulls out carbon dioxide as a separate stream, where it can be captured and kept out of the atmosphere.

CEO Parker Meeks tells Time, it's “a practical pathway to decarbonize existing industrial assets."

The startup is on a roll. It has raised $100 million so far in an ongoing Series D round to offer its decarbonization technology at industrial scale around the world.

H2Gen is joined by 10 other inventions with Texas connections onTime's list, as well as one "special mention."

In North Texas, they are:

Samsung
Plano-based Samsung Electronics America pulled off a hat trick this year, with three products making Time’s list. First up is the Galaxy S26 Ultra smartphone. It packs a more powerful camera, Galaxy AI features, and pro-level content creation tools. But Time singled out its new built-in privacy display as the phone’s “biggest selling point.”

Samsung’s Bespoke AI Family Hub refrigerator also got smarter. When AI first came to the Family Hub in 2024, it could recognize some fresh foods, but you still had to log packaged items by hand, Time noted. Now, with Google Gemini built in, the fridge can identify more than 2,000 packaged foods, read handwritten labels, and warn you when food is about to expire. It then uses what’s inside to build grocery lists and suggest recipes.

And for gamers, there’s the Odyssey G8 monitor. Its 6K resolution leapfrogs the 4K standard, delivering what Samsung calls “exceptional visual clarity and detail” on a screen big enough for gaming and multitasking.

OxeFit
Plano-based OxeFit’s XS1 Peak is about the size of a treadmill but works like an entire gym. It can be set up for strength training, simulated skiing or kayaking, Pilates, or rowing. What makes it stand out is a built-in virtual spotter. According to Time, the machine “uses AI, computer vision and sensors to correct the user’s form, change resistance in the middle of a rep and reduce the weight when the user is struggling, much like a human spotter.”

EssilorLuxottica
EssilorLuxottica, the French eyewear giant whose U.S. headquarters is in Farmers Branch, makes Essilor Stellest lenses. The lenses correct nearsightedness while also slowing the eye growth that makes it worse over time. Stellest is the first and only eyeglass lens authorized by the U.S. Food and Drug Administration to control myopia, Time said. The lenses look like regular glasses but contain 1,021 tiny lenslets. In a U.S. trial of kids ages 6-12, myopia progression slowed by an average of 71 percent over two years compared with standard lenses.

Helpany
Helpany, a startup based in Phoenix that manufactures its devices in DFW, makes Paul, a ceiling-mounted gadget that uses radar and AI to spot subtle changes in how residents move and flag those at higher risk of falling. Helpany says the technology can cut falls by as much as 72 percent.

Aurora Innovation
Aurora, based in Pittsburgh with a corporate and operations hub in Coppell, rolled out its second-generation Driver 2 system in July. By September, Driver 2 trucks had logged more than 500,000 driverless miles without a single at-fault crash, Time reported, and the company expects 200 of them on the road by the end of 2026.

Colossal Biosciences
Dallas-based Colossal Biosciences built an artificial egg by placing an ultra-thin, transparent silicone membrane inside a rigid 3D-printed cup, letting scientists watch the embryo develop. Twenty-six chickens have already been hatched.

In Austin, they are:
Cedar Park-based Hyliion landed on Time’s list with its Karno Power Module, a modular generator designed to produce power wherever it’s needed. The Karno represents a big pivot for the company. Hyliion got its start building electrified powertrains for 18-wheelers before shifting into power generation after acquiring the Karno generator technology from GE Aerospace. Founded in Pittsburgh in 2015, the company relocated to Cedar Park in 2018.

The other Austin-associated honoree is Moment Energy. As more electric vehicles hit the road, a growing number of their batteries are nearing retirement, while demand for power keeps climbing. Moment Energy found a way to tackle both problems at once. The company’s Megafactory 1, which opened in Vancouver, Canada, in June, turns old EV batteries into modular energy storage systems for hospitals, factories, data centers, and other big power users. “Our goal is to make sure these batteries don’t end up in landfills,” founder Edward Chiang told Time.

In the “Special Mentions” category, Austin-based Renzoe Box gained notice for its refillable custom makeup palette for on-the-go people. Licensed architect René Graham designed the box. She graduated from Houston's Rice University, and was born and raised in Dallas.

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A version of this article first appeared on CultureMap.com.

4 Houston health tech startups advancing medical innovation

meet the finalists

Houston has been driving medical innovation for decades. And thanks to leading hospitals, cutting-edge research and breakthrough technologies, the region’s healthcare ecosystem continues to improve how patients are diagnosed, treated and cared for.

The Health Tech Business category in our 2025 Houston Innovation Awards will honor an innovative startup within the health and medical technology sectors.

Four forward-thinking businesses have been named finalists for the 2026 award. This year's finalists, selected by our esteemed panel of judges, range from a startup developing miniaturized medical technologies for space to a company using AI to help develop cancer treatment plans.

Read more about these businesses, their innovative founders, and how they're shaping the future of health care below.. The 2026 winners will be announced on InnovationMap.com in mid-November.

Bairitone Health

Bairitone Health is bringing anatomy imaging for sleep apnea to the home environment. The company's platform maps users' anatomy during natural sleep using a facial patch to determine the root cause of airway obstruction. It then offers effective therapies for each patient.

The company was founded in 2022 in the Texas Medical Center's Biodesign program by CEO Meagan Pitcher, CTO Onur Kilic and chief medical officer Britt Cross. It was a member of Activate Houston's inaugural cohort and has participated in numerous accelerators and incubators. The company raised an oversubscribed seed round for $2.4 million earlier this year and received Breakthrough Device Designation from the Food and Drug Administration in April.

InformAI Inc.

InformAI Inc. develops fit-to-purpose AI solutions for the clinical setting. Its RadOncAI product recently received FDA 510(k) clearance. The product uses AI to create a first-pass radiation therapy dose plan for complex head and neck cancers in an effort to eliminate bottlenecks in radiation planning and ultimately cancer treatment. The company has also developed AI products for sinus disease detection and 3D organ reconstruction.

CEO Jim Havelka founded the company in 2017. It is participating in the Mayo Clinic Accelerate Platform. It has raised about $4 million in seed funding and has received numerous non-dilutive grants from the National Science Foundation, the National Institutes of Health and the Cancer Prevention and Research Institute of Texas. The company shared in its application that it plans to launch a Series A fundraising round and submit an FDA 510K application for its organ reconstruction product, Voluquant, by the end of 2026.

Prana Surgical

Prana Surgical is developing a minimally invasive surgical platform for small, hard-to-reach lung nodules that may be cancerous. The company's Prana System cleared U.S. Food and Drug Administration (FDA) approval earlier this year.

Prana Surgical was originally founded as Prana Thoracic in 2022. It has participated in numerous accelerators, including the Texas Medical Center Innovation Accelerator in 2023 and the IGNITE Health accelerator in 2022. It raised $6 million in Series A funding rounds in 2023 and 2024 , with a Series B currently ongoing. The company said in its application that it is currently moving into the next stage of clinical validation and revenue generation in the U.S., in addition to preparing its manufacturing and commercial infrastructure for broader use.

Skybound MedTech

Skybound MedTech develops technologies that aim to address the health risks of long-duration spaceflight. Its compact, miniaturized medical technologies can deliver complex therapies without a physician.

CEO Matthew Kuhn, who previously founded Taurus Vascular, founded Skybound last year. The company emerged from stealth in January after raising a $1.25 million Series A round. It plans to advance its lead dual-use platform into critical preclinical validation in November, the company shared in its application. It is currently raising a $25 million Series A round and is pursuing federal research partnerships with DARPA and ARPA-H.