who's who

3 Houston innovators to know this week

This week's Houston innovators to know includes Tudor Palaghita of Camppedia, Robert Kester of Honeywell, and Ed Wooten of Smith. Photos courtesy

This week's Houston innovators to know are all using technology — but in completely different ways and across various sectors.

From creating a circular and sustainable economy for your company's technology to an online platform for your child's various activities — and even a socially distant way of checking temperatures — here is this week's who's who of Houston innovation.

Tudor Palaghita, CEO and founder of Camppedia

Tudor Palaghita has advanced his startup, Camppedia, so that parents can have virtual and in-person activities for their kids this summer. Photo courtesy of Camppedia

Like most of the world, Tudor Palaghita's year isn't going as planned. The founder of Camppedia — an online marketplace and tool for parents finding and managing their kids' activities — was hoping this summer was going to be his company's break-out moment and proof of concept. Instead, he's had to act quickly and pivot to focus on community and virtual opportunities.

"If anything, the pandemic forced us to move a lot of things forward," Palaghita says on the recent episode of the Houston Innovators Podcast. "The focus on the community was also something coming earlier than planned, but it was the most wonderful thing to come out of this. It really feels like everybody came together to give and to help each other."

Camppedia's business model is to give local camp and program providers — mostly small businesses, Palaghita says — a place to seamlessly reach parents. Now, these providers need Camppedia's platform more than ever as parents seek options a as they return to work or continue to look for at-home entertainment for their kids. Click here to read more.

Robert Kester, founder of Rebellion Photonics and president and general manager at Honeywell

Robert Kester found a new use for his temperature monitoring tech he created for the oil and gas industry. Photo courtesy of Honeywell

As the pandemic began to spread across the country, Robert Kester saw an opportunity for his technology he built for the oil and gas industry. Kester founded Rebellion Photonics, which Honeywell acquired in December of last year, and the company's ThermoRebellion temperature software uses infrared imaging technology and artificial intelligence to quickly conduct non-invasive screenings of people before they enter offices, banks, airports, as businesses begin to reopen.

"The key component is our software powered by artificial intelligence," Kester tells InnovationMap. "Our imaging systems leverage a decade of experience in the most advanced imaging technologies for gas leak detection, fire detection, and intrusion monitoring applications. The system features uncooled high-resolution FPA infrared sensors allowing for each pixel to be assessed for temperature."

By Kester's and his team's estimates, the ThermoRebllion system will be ready to deploy as early as June. Click here to read more.

Ed Wooten, director of IT asset disposition at Smith

Building a circular economy for electronics requires attention to detail in the areas of design, buyback, or return systems, advanced recycling and recapturing, durability and repair, and urban mining, writes Ed Wooten. Photo courtesy of Smith

For 20 years, Ed Wooten has worked to help clients figure out how to navigate the processes of buyback, recycling, and repair in order to create sustainable and profitable solutions to reduce e-waste.

"The world produces 40 million tons of e-waste annually, and only 20 percent of that is being disposed of properly," Wooten writes in a guest column for InnovationMap. "A circular economy is a system in which all materials and components are kept at their highest value and where e-waste is essentially designed out of the system."

Wooten gives his advice for creating a circular economy. Click here to read more.

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A research team housed out of the newly launched Rice Biotech Launch Pad received funding to scale tech that could slash cancer deaths in half. Photo via Rice University

A research funding agency has deployed capital into a team at Rice University that's working to develop a technology that could cut cancer-related deaths in half.

Rice researchers received $45 million from the National Institutes of Health's Advanced Research Projects Agency for Health, or ARPA-H, to scale up development of a sense-and-respond implant technology. Rice bioengineer Omid Veiseh leads the team developing the technology as principal investigator.

“Instead of tethering patients to hospital beds, IV bags and external monitors, we’ll use a minimally invasive procedure to implant a small device that continuously monitors their cancer and adjusts their immunotherapy dose in real time,” he says in a news release. “This kind of ‘closed-loop therapy’ has been used for managing diabetes, where you have a glucose monitor that continuously talks to an insulin pump. But for cancer immunotherapy, it’s revolutionary.”

Joining Veiseh on the 19-person research project named THOR, which stands for “targeted hybrid oncotherapeutic regulation,” is Amir Jazaeri, co-PI and professor of gynecologic oncology at the University of Texas MD Anderson Cancer Center. The device they are developing is called HAMMR, or hybrid advanced molecular manufacturing regulator.

“Cancer cells are continually evolving and adapting to therapy. However, currently available diagnostic tools, including radiologic tests, blood assays and biopsies, provide very infrequent and limited snapshots of this dynamic process," Jazaeri adds. "As a result, today’s therapies treat cancer as if it were a static disease. We believe THOR could transform the status quo by providing real-time data from the tumor environment that can in turn guide more effective and tumor-informed novel therapies.”

With a national team of engineers, physicians, and experts across synthetic biology, materials science, immunology, oncology, and more, the team will receive its funding through the Rice Biotech Launch Pad, a newly launched initiative led by Veiseh that exists to help life-saving medical innovation scale quickly.

"Rice is proud to be the recipient of the second major funding award from the ARPA-H, a new funding agency established last year to support research that catalyzes health breakthroughs," Rice President Reginald DesRoches says. "The research Rice bioengineer Omid Veiseh is doing in leading this team is truly groundbreaking and could potentially save hundreds of thousands of lives each year. This is the type of research that makes a significant impact on the world.”

The initial focus of the technology will be on ovarian cancer, and this funding agreement includes a first-phase clinical trial of HAMMR for the treatment of recurrent ovarian cancer that's expected to take place in the fourth year of THOR’s multi-year project.

“The technology is broadly applicable for peritoneal cancers that affect the pancreas, liver, lungs and other organs,” Veiseh says. “The first clinical trial will focus on refractory recurrent ovarian cancer, and the benefit of that is that we have an ongoing trial for ovarian cancer with our encapsulated cytokine ‘drug factory’ technology. We'll be able to build on that experience. We have already demonstrated a unique model to go from concept to clinical trial within five years, and HAMMR is the next iteration of that approach.”

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