Here's how to make Houston the smartest city in America

Guest column

Houston's new Ion Smart Cities Accelerator director on making our town a smart one. Getty Images

In an age of autonomous vehicles, smart buildings, virtual reality, and 5G, more and more cities across the country are deploying smart technologies. The breadth of these technologies can result in many opportunities to share information, drive economic growth, create access, and enhance the quality of life, safety, and connectedness for a city's citizens and communities.

Recently listed as a city of the future, America's most diverse and fourth largest city, Houston, is leveraging these technologies - from driverless pizza delivery to flood detection sensors. Enhancing transportation, public safety, resiliency and sustainability, and community engagement are foundational to Houston's mission of building a smarter, more resilient future, especially in the face of natural disasters, such as hurricanes. These factors also shape the collaborative vision for Houston as a smart city that enjoys economic growth, promotes and practices inclusion, and prioritizes public safety.

So, how do we achieve this vision? As attributed to both Abraham Lincoln and Peter Drucker, "the best way to predict the future is to create it." This quotation speaks to the power of creativity in having a vision for what our future could look like, and in building this vision. To create this future, collaboration in the context of a strong, purposeful entrepreneurial ecosystem is crucial. With this in mind, Station Houston, an acceleration hub for startup technology companies, corporate innovation and entrepreneurship, has partnered with Microsoft, Intel, TX/RX Labs, and the city of Houston in spearheading the creation of the Ion Smart Cities Accelerator, which announced its formation in April.

The 10-month program will foster startups and entrepreneurs in developing smart city technology geared toward tacking transportation, resiliency, mobility, and other needs. Participants will have access to city of Houston officials, free membership to Station Houston for the duration of the program, curated events and training, and a state-of-the art makerspace, and much more. The accelerator will prepare startups with an MVP for the opportunity to pilot their technology-based solutions in the city of Houston. The accelerator will be based out of Station Houston, and will move to the Ion when it opens.

As we create Houston's future, we must do so through from the foundation of leveraging technology to create access, equity, and opportunity for all; promoting sustainability and safety; upholding civic values and inclusion; and seeking to meet our citizen's greatest needs.

To achieve a vision of Houston as America's smartest city, our most valuable currency is our ability to collaborate through relationships and partnerships that unite and empower communities. Smart technology must be grounded in connecting people and empowering communities to share data, information, and knowledge. In these ways, smart technology truly enables a city to serve, and celebrate, its greatest asset: its people.

If you are interested in participating in the Ion Smart Cities Accelerator, please apply here. Our website has a frequently asked questions section, a note from the director, and relevant media and news articles about the accelerator

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Christine Galib is the program director of the Ion Smart Cities Accelerator.

Station Houston has a new hire. Christine Galib was named as the director of the Ion Smart Cities Accelerator. Natalie Harms/InnovationMap

New accelerator director at Station Houston wants to bring talent and impactful startups to town

On the job

When Christine Galib moved to Houston, she knew two things: it was going to be hot, and there were going to be tacos. But when Hurricane Harvey hit in 2017, she learned something else: the resiliency of the city — and its people — was a thread that interwove the fabric of the metro.

And now that the Ion Smart Cities Accelerator, a program that would allow participants to find solutions to real-world problems in Houston, has now hired Galib as its first program director. Through her position, she'll be able to guide participants from all over the country find solutions to two of the city's biggest problems: transportation and mobility.

"Houston is international, resilient, and inspirational, powered by innovation, energy, and diversity that forms a strong foundation for our unique entrepreneurial ecosystem," Galib says in a news release announcing her hiring. "I am excited to serve Houston through leveraging and creating collaborations, partnerships, and solutions to differentiate Houston as a smart city that is building for its future."

Station Houston will host the accelerator through its first cohort, but it will move to The Ion when the innovation hub opens in 2020.

"When we look at The Ion being created as a center for entrepreneurship and innovation in Houston, there's no other city in the world has this type of level of collaboration and transparency of major players in the innovation space coming together to create, not only the physical space, but also the programming and mindset and the environment and the culture to sustain it," she tells InnovationMap.

"It was a pretty easy decision for me to be on board with the vision. It's not just a vision for a future which is far off … It's a vision for the future that we're actually creating today."

Galib, a former instructor at Rice University and the University of St. Thomas who has experience as a financial analyst on Wall Street, will spearhead the Ion Smart Cities Accelerator. For her, leading the Ion Smart Cities Accelerator allows her to take part in creating a forward-thinking, solutions driven program that will help usher in that culture into Houston's entrepreneurial atmosphere — collaboration is key.

"When I think of Houston and innovation, I think this collaborative approach to making something that is going to stick — sustainable change that sticks — and then making a future that is not just different but better for everybody," Galib says.

The accelerator, which was announced by Mayor Sylvester Turner at a Microsoft IoT in Action event, is now accepting applications for its first cohort. Galib says access is one of the biggest assets applicants are given if given the opportunity to join the accelerator.

"One of the goals is inclusion," Galib says. "You can't have a smart city and have that smartness benefit only one or two percent of the people. The inclusive nature of the accelerator in this entrepreneurial ecosystem is a major selling point."

Participants of the 10-month program will participate in structured curriculum and programming focused on mobility and resiliency and are tasked with creating feasible solutions to those problems within the city.

Galib, along with Station Houston, will offer participating entrepreneurs and startups with the resources they need to validate their solutions and prepare them for deployment, as well as create programming for participants and lead the research and analysis for the accelerator.

Galib is excited to attract talent into the first cohort and see what they do throughout their tenure in the accelerator.

"(We want to identify and recruit) talent to come to Houston and to stay in Houston, to be part of a family of entrepreneurs in innovation," she says. "I had no family here when I came here, and one of the reasons why I stayed here was because I found people who really got me excited about being a Houstonian."


Christine Galib will lead the Ion Smart Cities Accelerator program. Photo via StationHouston.com

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

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