Elizabeth Holmes, pictured on November 18, is now incarcerated. Photo by Justin Sullivan/Getty Images

A longtime Houstonian is coming home — by way of prison.

Elizabeth Holmes, the disgraced founder of blood-testing startup Theranos, reported to F.P.C. Bryan, on Tuesday, May 30, per multiple news outlets. She is set to serve 11 years and three months in the women's minimum-security prison located some 90 minutes from Houston hometown.

According to the the New York Times, the onetime Tanglewood resident arrived at the prison in a Ford Expedition that appeared to be driven by her mother, Noel Holmes. Her father, Christian Holmes, appeared to be inside.

The Times adds that after some shuffling around, out of the view of the cameras gathered nearby, Holmes entered the facility wearing jeans, glasses and a sweater, and carrying some papers.

Prior to her arrival in Bryan, Holmes, 39, spent Memorial Day weekend with her family on the beach near her oceanfront San Diego home with her partner Billy Evans and their two children, according to the Daily Mail.

As CultureMap previously reported, Holmes was sentenced to more than 11 years in prison on November 18, 2002 in San Jose, California following her conviction in January that year for defrauding Theranos investors.

Actress Amanda Seyfried, who played Holmes in the Hulu series The Dropout, shared her thoughts on the woman she portrayed to great acclaim. “Life’s not fair,” Seyfried noted on Good Morning America on Tuesday, “but in a lot of ways, it’s fair. For her, in particular.”

Thrust into the spotlight as the new face of white-collar, Silicon Valley fraud, Holmes now serves as a warning to those who might consider a similar path, her sentencing judge made clear.

“I suppose we step back and ask what is the pathology of fraud? Is it the refusal to accept responsibility or express contrition in any way?" Judge Edward Davila said during the ruling, according to Yahoo! Finance. "Perhaps that is the cautionary tale that will go forward from this case."

Davila ordered Holmes to turn herself into custody on April 27, 2023.

Specifically, Holmes' sentence is 11 years and three months in prison, with another three years of supervision after release. Additionally, Holmes and her ex-boyfriend and former Theranos COO Ramesh “Sunny” Balwani have been ordered to pay $452 million to their fraud victims.

Once compared to disruptors and innovators Steve Jobs and Bill Gates, Holmes rose to fame by enticing investors with the promise that her Theranos could run hundreds of blood tests via a simple pin prick. Buzz for Theranos grew to the point that Theranos was valued at $9 billion, which made Holmes the world’s first self-made female billionaire.

Yet, after securing more than $900 million in funding, Theranos was proven to be essentially bogus by the Wall Street Journal in 2015.

Facing up to 20 years in prison, a tearful Holmes, who is pregnant, addressed the court. "I stand before you taking responsibility for Theranos," she said, per Yahoo. "I loved Theranos. It was my life’s work. My team meant the world to me. They wanted to make a difference in the world. I am devastated by my failings," she said. "Every day for the past years, I have felt deep pain for the people…those people who believe in us and those patients. I worked so hard to serve. I gave everything I had to try to to build...Theranos. Looking back, there are so many things I would do differently. I tried to realize my dream too quickly."

Holmes is the subject of the aforementioned series, The Dropout, which centers on her early life in Houston, where she grew up in Tanglewood and attended St. John's School. Her father's layoff from Enron is presented as clearly an inciting incident in her life. As The Dropout depicts, Holmes would meet boyfriend/partner Ramesh "Sunny" Balwani, drop out of Stanford, and launch Theranos.

One of the most memorable lines in the miniseries comes when a young Holmes plainly states her goals at a family gathering. "I wanna be a billionaire," she said plainly — a memorable and clearly prophetic statement.

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This article originally ran on CultureMap.

Reports find that more and more tech companies are leaving the bustling Silicon Valley. But where exactly are they going? Miguel Tovar/University of Houston

If Silicon Valley is experiencing a tech exodus, what does that mean for growing startup hubs like Houston?

houston voices

It started with prunes. Long before Silicon Valley was the innovation capital of the world, it was a giant valley of fruit trees and verdant hills. The primary crop in the then called Santa Clara Valley was the French plum, which was sun-dried to turn into the valley's most popular export and métier: prunes.

By the late 19th century, the Industrial Revolution had produced myriad millionaires, billionaires by the boatload and tons of tycoons. Among them was Leland Stanford, a railroad king. Stanford owned an 8,100-acre ranch in Santa Clara Valley near Palo Alto. That's where he founded and established Stanford University. It was also here that the region transformed into the valley of technology known today as Silicon Valley.

In 1925, Stanford alum Frederick Terman, considered the father of Silicon Valley, returned to teach radio engineering. Over the next decade, Terman noticed something quite concerning. He recognized that Stanford produced elite, highly-educated grads who continually opted to leave town for jobs in New York City. Terman expressed his desire for Stanford alumni to stay in the valley to grow the region's business sector and feed the local economy. The first company to heed this advice was Hewlett-Packard.

Terman encouraged Stanford grads William Hewlett and David Packard to partner up and thus, we saw the first ever "garage-startup" born. Anon this historic partnership, more alumni and faculty at Stanford began to found their own companies in the valley. Soon, a massive network of companies was formed, bound by their shared connection with the university. Terman had essentially built a pipeline through which Stanford grads poured into the valley, a process that is still in full swing today.

In a sense, Silicon Valley was the first academic incubator. One that is stronger than ever today. Or is it?

The great tech-xodus?

According to The Economist, "[In 2018,] more Americans left the county of San Francisco than arrived. According to a recent survey, 46 percent of respondents say they plan to leave the Bay Area in the next few years, up from 34 percent in 2016. So many startups are branching out into new places that the trend has a name, 'Off Silicon Valleying.'"

Business Insider's Melia Robinson writes, "Silicon Valley is on the brink of an exodus" and that "the tech elite are abandoning Silicon Valley in droves."

More tellingly, Kevin Roose wrote in his New York Times article "Silicon Valley Is Over, Says Silicon Valley," that "This isn't a full-blown exodus yet. But in the last three months of 2017, San Francisco lost more residents to outward migration than any other city in the country."

Roose followed 12 venture capitalists on a bus trip throughout the heartland. They were looking for hot startups in lesser-visited areas of America. The venture capitalists were in awe of how inexpensive the home prices were in the Midwest compared to the Bay Area. To add to this, a public-relations firm named Edelman conducted a survey of 500 residents in the Bay Area and found that almost half of all Bay Area residents "said they would consider leaving California because of the cost of living."

Moreover, Eric Rosenbaum wrote in his CNBC article "Silicon Valley Edged Out: Google Employees Aren't the Only Ones Walking Away From Elite Tech Headquarters," that "Silicon Valley is not about to lose its dominant position as the home of billion-dollar technology start-ups and hub for top talent, but there are a growing number of reasons why more workers and new companies are choosing other cities, far from San Francisco."

The common theme in most of the aforementioned articles is that the reason behind this mini-exodus is the high cost of living in the Bay Area. The Economist states that "young startups pay at least four times more to operate in the Bay Area than in most other American cities."

Aside from the cost of living, one often-cited reason why entrepreneurs leave the Valley is groupthink. Again, The Economist sheds light on this stating that, "The Valley does many things remarkably well, but it comes dangerously close to being a monoculture of white male nerds. Companies founded by women received just 2 percent of the funding doled out by venture capitalists last year (2017)." Entrepreneur Tim Ferriss told Business Insider that the tech scene in Silicon Valley can be brutal for people who deviate from the political echo chamber. After ten years in the Valley, Ferriss moved to Austin in 2017. Business Insider also tells the account of Peter Thiel, a billionaire-investor who was all but ostracized from Silicon Valley because of his support for President Donald Trump. He told Insider that "Network effects are very positive things, but there's a tipping point where they fall over into the madness of crowds."

Even if not quite an exodus, there are many accounts like the aforementioned that point to the fact that startups are indeed looking for greener pastures. Just where are these greener pastures? They are located in the business districts and technology parks that are smaller versions of Silicon Valley in cities all over the country. However, one green pasture in particular has taken the startup world by storm in recent years: the rise of the academic incubator.

A tech-splosion of university parks

"In recent years, there has been a substantial increase in public and private investment in university research parks (URPs). URPs are important as an infrastructural mechanism for the transfer of academic research findings, as a source of knowledge spillovers, and as a catalyst for national and regional economic growth," wrote Albert N. Link and John T. Scott in the highly regarded journal Oxford Review of Economic Policy, in their article "The economics of university research parks."

One of the biggest reasons universities have become hotbeds for tech startups is that campuses provide a means for people with multidisciplinary backgrounds to intermingle within the same space. A mechanical engineering student with a great idea might meet an MBA during a startup launch party. Together they can build and market their time-traveling DeLorean, or whatever actually-realistic idea the student has.

In essence, academic incubators are courting tech entrepreneurs because universities offer an ecosystem designed to support and grow startups from conception to commercialization. This ecosystem includes a space where researchers, faculty and students of all disciplines interact and form working relationships. In many cases, it also includes university owned equipment and laboratories for use by startup researchers.

"I feel that organizations working to commercialize university IP realize a great source of off-the-shelf technology that small businesses can use to either augment their own offerings or exploit something not currently found in the marketplace," said Michael Tentnowski, the director of entrepreneurship for Innovation Park of Tallahassee.

"Basically, the potential business can work with university staff to perfect, enhance or create new versions of various innovations to appeal to consumer demands. Taking the technology risk out of the equation helps new businesses focus on customer discovery and market penetration," Tentnowski explained.

Faye Liu, founder and CEO of RevoChem, a hot startup that recently launched out of UH's Technology Bridge, expressed that "one key benefit is the easy access to great talents and research resources from both students, researchers and professors from the university with flexibility."

Liu goes on to explain, "We have successfully hired multiple UH students and alumni through internships to work full time. We have also sponsored UH research that is relevant to our work which is a win-win for both of us."

It is true that universities position aspiring entrepreneurs to network with the right people for building their company from the ground up. Even the Innovation Leadership Forum attests that innovation is born when different ways of thinking clash.

"Providing a high-density area for collisions between thoughts and ideas to occur is driving innovation. Our urban location – adjacent to a Tier One research university – provides the chance for success to increase exponentially," said Carrie Roth, the president and CEO of Virginia Bio Tech Park.

"Our experience demonstrates that startups come here for a competitive advantage – and that is being in an environment where they can keep costs lower and accelerate their startup," she continued.

Academic incubators exude a different aura from non-academic parks. There's a certain sense of prestige they carry because they are based in universities. Perhaps it is the idea of working with professors and using university labs and equipment that resonates. "University research parks offer the opportunity for startups to be at the nexus of technology, talent and opportunities. The UH Technology Bridge, for example, offers a unique setting where companies from a broad range of technology areas can come together and have access to a variety of different resources, including wet lab space," explained Christopher Taylor, the executive director of University of Houston's Office of Technology Transfer and Innovation.

"Locating in a research park near a major university offers startups a chance to engage and collaborate with academic researchers in their field and leverage the vast talent pool of students through internships and part-time employment to develop their technology and grow their company," Taylor proceeded.

Yes, it is no wonder that so many entrepreneurs are choosing to leave Silicon Valley. They actually have options now. There are a ton of alternatives available all over the country now that are just as "top tier" as Silicon Valley, without the drawbacks of living there. Chief among these alternatives are academic incubators. The explosion of university investment in these tech parks has opened, nay, kicked down, the door for startup founders looking to venture outside of the Bay Area.

Say what you will about the mini-exodus from Silicon Valley. The high cost of living, the echo chamber and political groupthink, the lack of diversity. All valid points. But one thing is for certain, there are no academic incubators today without Silicon Valley. Its influence on modern tech parks may be taken for granted, but it is real.

It was once said that as gigantic and unfathomably massive as the sun is, it still manages to gently reach out with its light, millions of miles away, to ripen a vine of grapes as if it had nothing better to do. That's how Silicon Valley's influence is felt. Except instead of ripening grapes, it's drying plums. And today, academic and non-academic incubators merely operate in its shadow. The shadow of the valley of tech.

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This article originally appeared on the University of Houston's The Big Idea. Rene Cantu, the author of this piece, is the writer and editor at UH Division of Research.

Baker Botts is connecting the dots between its HQ, its startup-focused Silicon Valley outpost, and Texas accelerators. Nick Bee/Pexels

Houston-based international law firm forms partnerships with local startup accelerators

dream team

In order to keep up with the growing startup ecosystem in Houston, Baker Botts is connecting the dots between its Silicon Valley venture and entrepreneurial hub to strategic partnerships in its headquarters of Houston.

Houston-based Baker Botts L.L.P., an international technology and energy law firm, established its Emerging Companies and Venture Capital arm in Palo Alto, California, in 2009. Now, in order to tap into Texas startups, the firm has created strategic partnerships with three accelerator organizations: The Cannon, Station Houston, and Capital Factory.

"These three strategic partnerships provide an exciting opportunity to showcase the depth and breadth of our technology sector experience in the startup, venture capital and entrepreneur community," says Baker Botts managing partner, John Martin, in a release. "We have a history of working with emerging and technology companies throughout their full life cycle, and we expect these partnerships will expand those opportunities more broadly. Some of our firm's largest clients are businesses with which we have worked since they were startups themselves."

This news comes on the heels of The Ion breaking ground on July 19, the release notes, which represents another major collaborative effort and advancement of innovation in Houston.

"It is exciting to see Baker Botts expand its involvement with the Houston startup ecosystem," says Brad Burke, managing director of the Rice Alliance for Technology and Entrepreneurship, in the release. "The firm has a long history of supporting entrepreneurs in the region and has been a partner and supporter of the Rice Alliance and the Rice Business Plan Competition since 2002. The firm's expertise and connections will be of great value to startups in the Houston region. With the launch of the Ion in midtown, the launch of new accelerators, and the support of firms like Baker Botts, Houston is poised to transform its entrepreneurial landscape."

The strategic partnerships will put each accelerator and innovation hub in direct communication with Baker Botts' Emerging Company and Venture Capital practice, led by Brian Lee, partner-in-charge of the firm's Palo Alto office. The ECVC provides advice for entrepreneurs and startups, as well as connects them with investors and various industry professionals.

"In forming these partnerships, Baker Botts will be working with a range of innovative, Texas-based companies from the ground up," says Samantha Crispin, Baker Botts' technology sector chair, in the release. "One of the most intriguing aspects of these partnerships is the expected cross-pollination of our Texas and California ECVC practices and that the most promising companies will gain exposure to potential investors, including those in Silicon Valley."

Tech startups are leaving Silicon Valley in droves — and some are finding benefits in heading back to school. Miguel Tovar/University of Houston

Siliconned: Leaving Silicon Valley for universities

Houston Voices

Silicon Valley has been a tech startup paradise for decades. It has been described as the modern day Florence in the Renaissance. Tech gods from Apple and Google to Facebook and Twitter were born here. We can credit Silicon Valley as the birthplace for such world-changing innovations like smartphones, microprocessor chips, Tesla automation, and WIFI-enabled teapots.

Okay, so maybe that last one isn't changing the world, but it was created in the Valley and it's changed my life, for whatever that's worth. If Silicon Valley were a country, it would have the 19th-biggest economy on the planet. There's no doubt it is an engineer's dream. A techie's haven. A capitalist's utopia. A beacon of the modern world.

Or at least, it used to be.

Now leaving the Bay Area

There is an exodus in Silicon Valley. It's been happening for about three years. For instance, according to a 2018 poll conducted by the Bay Area Council, 46 percent of survey takers admit they plan to leave the Bay Area in the next year. Couple that with the fact that Silicon Valley investors have allocated 66 percent of their funds into startups outside of Silicon Valley, compared with 50 percent just six years ago, and you have a recipe for a great exodus to other markets around the country.

Now, just for kicks, add to all of this that the Kauffman Foundation's research has pegged Miami-Fort Lauderdale as the number one city in America for startup activity. Where does Silicon Valley's Bay Area, formerly the world's preeminent hub for tech startups, rank? Fourteenth. How the mighty have fallen.

So, to what exactly can this mass egress be attributed?

Insufficient funds

The biggest reason is cost.

The cost of living in the Bay Area is one of the steepest on the planet. Startups in the Valley pay four times what they would in any other city in the country. In fact, just last year the California Association of Realtors reported that a typical family in San Francisco has to make over $300,000 a year in order to afford a median-priced house tagged at just over a million dollars. That includes a 20 percent down payment and an $8,000 monthly payment. Because most of the startups in Silicon Valley are in their infancies, the engineers, programmers, and non-technical employees don't get compensated enough to afford such a living. As a result, they are leaving the Bay Area in droves for places where the cost of living is manageable.

One location that tech startup entrepreneurs are flocking to is the university. Universities are also retaining tech wunderkinds on campus to blossom their startups, rather than seeing them leave for the microprocessor motherland known as Silicon Valley.

Now entering university life

One of the biggest reasons universities have become hotbeds for tech startups is that campuses provide a means for people with multidisciplinary backgrounds to intermingle within the same space. A chemical engineering student with a great idea might meet an MBA during a startup launch party. Together they can build and market the second iteration of "Secret Stuff" from Space Jam, or whatever that student has in mind.

The point is that universities position aspiring entrepreneurs to network with the right people for building their company from the ground up. Even the Innovation Leadership Forum attests that innovation is born when different ways of thinking clash. That is precisely what happens on campuses every day.

Furthermore, college students also have more room to take risks. Most aspiring entrepreneurs in college between 18 and 25 are not married, do not have kids, mortgages, or any other major financial responsibilities. This allows them to have the luxury of leeway when it comes to experimenting and trial and error.

The ecosystem of innovation

In essence, academic incubators are courting tech entrepreneurs because universities offer an ecosystem designed to support and grow startups from conception to commercialization. This ecosystem includes a space where researchers, faculty, and students of all disciplines interact and form working relationships. In many cases, it also includes university owned equipment and laboratories for use by startup researchers.

There is, of course, incentive for universities to concentrate so many resources to building incubators and luring startup entrepreneurs. There is an inherent sense of responsibility that universities have to create an academic climate that encourages students to explore new ideas. A sense of responsibility that encourages them to take more risks; to be fearless in their quest to use their intellect to enrich lives; to dream.

Moreover, university incubators also position schools as progressive institutions. Such positioning attracts elite researchers and enhances a university's reputation. Further, these incubators forge a bridge that links industry and academia in a way that Silicon Valley does not. That's because with academic incubators, startups are a stone's throw away from a place teeming with researchers, scientists, hungry students, and aspiring entrepreneurs: the university campus.

Consequently, it is no wonder that tech startups are leaving Silicon Valley for universities. It's also no surprise that students who have graduated are staying with their university's incubators to develop their companies. There, they have a place that cultivates innovation, encourages risk-taking, and is set up specifically to help them bring their tech to the world. In short, the university has become a hub set up to be conducive to thriving tech startups. And tech entrepreneurs have noticed.

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This article originally appeared on the University of Houston's The Big Idea.

Rene Cantu is the writer and editor at UH Division of Research.

Ahead of entering the Houston market later this year, Silicon Valley's Plug and Play hosted three days of programming surrounding innovation in energy and health care. Natalie Harms/InnovationMap

Overheard: Prominent business leaders weigh in on innovation in the energy and health industries

Eavesdropping in Houston

Plug and Play, a Silicon Valley venture capital firm and accelerator program, plans to launch its operations in Houston later this year. And, in showing its commitment to the Bayou City, the organization hosted three days worth of panels, talks, and pitches at the Texas Medical Center's TMC Innovation Institute earlier this month.

Houston Innovation Week was Plug and Play's formal introduction to Houston startups and the local corporations that have the potential to support them. The programming focused on health and energy and sustainability, and the summit concluded with TMCx's Demo Day.

If you missed the event, we've hit the highlights for you by rounding up nine powerful quotes overheard throughout the week.

“Nowadays, I feel every industry is going to go through an incredible digital transformation. Even the oil and gas industry, which is very capital heavy, there’s going to be a layer of fast-moving technologies which would help the industry be more efficient. This is the crossroads where Plug and Play was born — bridging the gap between the entrepreneurs and the technologies. That changes an industry.”

— Saeed Amidi, CEO and founder of Plug and Play, says. He also shares the story of how Plug and Play got its start from a few lucky early investments to making over 150 investments a year.

“Now we have about 30 offices, and then quite frankly I realized I had forgotten about America.”

— Amidi says, announcing that Plug and Play will open five new offices across the United States in the next six months to a year.

“We’re not walking in terms of building this integrated robust innovation ecosystem, we’re sprinting in that direction.”

— Mayor Sylvester Turner says, adding that, "If there is any city that ought to be leading the way when it comes to startups, technology, and innovation, it ought to be the city of Houston."

“You have to get people to invest more. It doesn’t happen on its own. People have to see that if we invest, we’re going to get a return.”

— Mayor Turner says, calling the crowd to action. "You can't just talk about what others have done and what we have accomplished. You have to take that now, build the platform, and move into where we are going."

“One of the things you look at is it’s not the technology itself that’s going to make you win or lose, it’s what you do with it.”

— Barbara Burger, president of Chevron Technology Ventures, responding to a question about what technologies she has her eyes on. Burger continued on to say that, while she couldn't highlight any technologies in particular — it's like picking a favorite child, she's always evaluating how a new technology would help with the affordability, reliability, and lower environmental impact. "That's the game," she says.

"Management is amazing at suppressing innovation. … We can move toward just trying not to suppress it. If someone has an idea, they are safe to go through the process and raise their hand."

— Bradley Andrews, president of digital at Worley. "I think it's a change in attitude," he says about how management can evolve to advance ideas within energy companies.

“It’s easy to say that we’ll do the thing that gives us the most competitive advantage — and it’s really hard to figure out what that means and how you do that. In general, if we see something that’s out there and implemented that someone else has done, I don’t need to create an internal capability like that. I just need to go access that.”

— Doug Kushnerick, senior technology scouting and venture adviser at ExxonMobil. For Kushnerick, technology solutions that fix specific problems are easy to go after, but things that affect big picture and strategic assets are harder to figure out if they are worth implementing.

“One of our big asks from our partners from an internal perspective is really to have a champion — whether its an innovation manager or someone who really advocates these startups internally. Someone who will find the clinician and the business unit and tap the legal team.”

— Neda Amidi, global head of health and partner at Plug and Play Tech Center, responding to a question about opening up the channels of communications between startups and large companies. She adds that it's a requirement for these people to visit a Plug and Play location four to six times a year.

“What I see from a culture perspective is that it really starts with the leadership in the institution. If the people at the top in the C-suite of the institution are focused on understanding why their organization isn’t performing as well as they expect it to be and are willing to look to the outside, that’s how it starts in my mind.”

— Thomas Luby, director TMC Innovation Institute, responding to a question from the audience about large organizations that tend to be slower adaptors to new technologies.

Houston-based Tachyus closed a $15 million Series B round. Photo courtesy of Thomas Miller/Breitling Energy

Houston oil and gas software company closes $15 million round led by local PE firm

Money on the mind

It's pay day for Houston-based Tachyus. the data-driven software company has closed its Series B fundraising round at $15 million. The round was led by Houston-based Cottonwood Venture Partners, a private equity firm that funds companies using technology to solve problems within the energy industry.

Tachyus was founded in 2013 in Silicon Valley and recently relocated to Houston. The fresh funds will go into growing its cloud-based, artificial intelligence-enabled platform.

"In this economic environment, oil and gas operators need disruptive tools to optimize their fields," Tachyus CEO and co-founder, Paul Orland, says in a release. "This investment allows us to reach more customers and accelerate the delivery of new technology that improves our clients' business performance."

The company has already grown its client base and has customers in Argentina, Europe, and Asia. Tachyus joins several other tech-focused energy startups in CVP's portfolio, including Ambyint, Novi Labs, and SitePro. Houston-based Tudor, Pickering, Holt & Co. served Tachyus as its financial adviser.

"As the oil and gas industry evolves in the face of new commercial challenges, operators need to focus on getting the best performance from their assets, and Tachyus' technology has a track record of doing just that," says Jeremy Arendt, managing partner of CVP, in the release. "We are excited to partner with the Tachyus team to expand their reach and empower customers to optimize production across their fields."

Tachyus closed its last round in 2016 with a $4 million investment from Primwest, according to CrunchBase. Before that, the company had raised several million.

Last year, the startup restructured its C-suite. Tachyus co-founder Dakin Sloss transitioned from CEO to chairman, and Orland, who was previously CTO, took the reins, according to a release.

Paul Orland is CEO of Tachyus. Photo via tachyus.com

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Meet 6 mentors who are helping the Houston startup scene flourish

meet the finalists

Few founders launch successful startups alone — experienced and insightful mentors often play an integral role in helping the business and its founders thrive.

The Houston startup community is home to many mentors who are willing to lend an ear and share advice to help entrepreneurs meet their goals.

The Mentor of the Year category in our 2025 Houston Innovation Awards will honor an individual like this, who dedicates their time and expertise to guide and support budding entrepreneurs. The award is presented by Houston City College Northwest.

Below, meet the six finalists for the 2025 award. They support promising startups in the medical tech, digital health, clean energy and hardware sectors.

Then, join us at the Houston Innovation Awards this Thursday, Nov. 13 at Greentown Labs, when the winner will be unveiled. The event is just days away, so secure your seats now.

Anil Shetty, InformAI

Anil Shetty serves as president and chief medical officer for biotech company Ferronova and chief innovation officer for InformAI. He's mentored numerous medical device and digital health companies at seed or Series A, including Pathex, Neurostasis, Vivifi Medical and many others. He mentors through organizations like Capital Factory, TMC Biodesign, UT Venture Mentoring, UTMB Innovation and Rice's Global Medical Innovation program.

"Being a mentor means empowering early-stage innovators to shape, test, and refine their ideas with clarity and purpose," Shetty says. "I’m driven by the opportunity to help them think strategically and pivot early before resources are wasted. At this critical stage, most founders lack the financial means to bring on seasoned experts and often haven’t yet gained real-world exposure. Mentorship allows me to fill that gap, offering guidance that accelerates their learning curve and increases the chances of meaningful, sustainable impact."

Jason Ethier, EnergyTech Nexus

Jason Ethier is the founding partner of EnergyTech Nexus, through which he has mentored numerous startups and Innovation Awards finalists, including Geokiln, Energy AI Solutions, Capwell Services and Corrolytics. He founded Dynamo Micropower in 2011 and served as its president and CEO. He later co-founded Greentown Labs in Massachusetts and helped bring the accelerator to Houston.

"Being a mentor means using my experience to help founders see a clearer path to success. I’ve spent years navigating the ups and downs of building companies, struggling with cash flow, and making all the mistakes; mentoring gives me the chance to share those lessons and show entrepreneurs the shortcuts I wish I’d known earlier," Ethier says. "At Energytech Nexus, that role goes beyond just helping individual founders — it’s about creating a flywheel effect for Houston’s entire innovation ecosystem."

Jeremy Pitts, Activate Houston

Jeremy Pitts serves as managing director of Activate Houston, which launched in Houston last year. He was one of the founders of Greentown Labs in the Boston area and served in a leadership role for the organization between 2011 and 2015. Through Activate, he has mentored numerous impactful startups and Innovation Awards finalists, including Solidec, Coflux Purification, Bairitone Health, Newfound Materials, Deep Anchor Solutions and others.

"Being a mentor to me is very much about supporting the person in whatever they need. Oftentimes that means supporting the business—providing guidance and advice, feedback, introductions, etc," But just as important is recognizing the person and helping them with whatever challenges they are going through ... Sometimes they need a hype man to tell them how awesome they are and that they can go do whatever hard thing they need to do. Sometimes they just need an empathetic listener who can relate to how hard these things are. Being there for the person and supporting them on their journey is key to my mentorship style."

Joe Alapat, Liongard

Joe Alapat founded and serves as chief strategy officer at Houston software company Liongard and chief information officer at Empact IT, which he also owns. He mentors through Founder Fridays Houston Group, Software Day by Mercury Fund, SUPERGirls SHINE Foundation, Cup of Joey and at the Ion. He's worked with founders of FlowCare, STEAM OnDemand, Lokum and many other early stage startups.

"Being a mentor to me means unleashing an individual’s 10x—their purpose, their ikigai (a Japanese concept that speaks to a person’s reason for being)," Alapat says. "Mentoring founders in the Houston community of early stage, high-growth startups is an honor for me. I get to live vicariously through a founder’s vision of the future. Once they show me that compelling vision, I’m drawn to bring the future forward with them so the vision becomes reality with a sense of urgency."

Neal Dikeman, Energy Transition Ventures

Neal Dikeman serves as partner at early stage venture fund Energy Transition Ventures, executive in residence at Greentown Labs, and offices in and supports Rice Nexus at the Ion. He mentors startups, like Geokiln, personally. He also mentored Helix Earth through Greentown Labs. The company went on to win in the Smart Cities, Transportation & Sustainability contest at SXSW earlier this year. Dikeman has helped launch several successful startups himself, most recently serving on the board of directors for Resilient Power Systems, which was acquired by Eaton Corp for $150 million.

"Founders have to find their own path, and most founders need a safe space where they can discuss hard truths outside of being 'on' in sales mode with their team or board or investors, to let them be able to work on their business, not just in it," Dikeman says.

Nisha Desai, Intention

Nisha Desai serves as CEO of investment firm Intention and mentors through Greentown Labs, TEX-E, Open Minds, the Rice Alliance Clean Energy Accelerator, Avatar Innovations and The Greenhouse. She currently works with founders from Solidec, Deep Anchor Solutions, CLS Wind and several other local startups, several of which have been nominated for Innovation Awards this year. She's served a board member for Greentown Labs since 2021.

"When I first started mentoring, I viewed my role as someone who was supposed to prevent the founder from making bad decisions. Now, I see my role as a mentor as enabling the founder to develop their own decision-making capability," Desai says. "Sometimes that means giving them the space to make decisions that might be good, that might be bad, but that they can be accountable for. At the end of the day, being a mentor is like being granted a place on the founder's leadership development journey, and it's a privilege I'm grateful for."

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Rice, Houston Methodist developing soft 'sleep cap' for brain health research

Researchers and scientists at Rice University and Houston Methodist are developing a “sleep cap” that aims to protect the brain against dementia and other similar diseases by measuring and improving deep sleep.

The project is a collaboration between Rice University engineering professors Daniel Preston, Vanessa Sanchez and Behnaam Aazhang; and Houston Methodist neurologist Dr. Timea Hodics and Dr. Gavin Britz, director of the Houston Methodist Neurological Institute and chairman of the Department of Neurosurgery.

According to Rice, deep sleep is essential for clearing waste products from the brain and nightly “cleaning cycles” help remove toxic proteins. These toxic proteins, like amyloids, can accumulate during the day and are linked to Alzheimer’s disease and other neurological issues.

Aazhang, director of the Rice Neuroengineering Initiative, and his team are building a system that not only tracks the brain’s clearing process but can also stimulate it, improving natural mechanisms that protect against neurodegeneration.

Earlier proof-of-concept versions of the caps successfully demonstrated the promise of this approach; however, they were rigid and uncomfortable for sleep.

Preston and Sanchez will work to transform the design of the cap into a soft, lightweight, textile-based version to make sleep easier, while also allowing the caps to be customizable and tailored for each patient.

“One of the areas of expertise we have here at Rice is designing wearable devices from soft and flexible materials,” Preston, an assistant professor of mechanical engineering, said in a news release. “We’ve already shown this concept works in rigid device prototypes. Now we’re building a soft, breathable cap that people can comfortably wear while they sleep.”

Additionally, the research team is pursuing ways to adapt their technology to measure neuroinflammation and stimulate the brain’s natural plasticity. Neuroinflammation, or swelling in the brain, can be caused by injury, stroke, disease or lifestyle factors and is increasingly recognized as a driver of neurodegeneration, according to Rice.

“Our brain has an incredible ability to rewire itself,” Aazhang added in the release. “If we can harness that through technology, we can open new doors for treating not just dementia but also traumatic brain injury, stroke, Parkinson’s disease and more.”

The project represents Rice’s broader commitment to brain health research and its support for the Dementia Prevention Research Institute of Texas (DPRIT), which passed voter approval last week. The university also recently launched its Rice Brain Institute.

As part of the project, Houston Methodist will provide access to clinicians and patients for early trials, which include studies on patients who have suffered traumatic brain injury and stroke.

“We have entered an era in neuroscience that will result in transformational cures in diseases of the brain and spinal cord,” Britz said in the release. “DPRIT could make Texas the hub of these discoveries.”

Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.