UH's business school has been recognized for innovation and entrepreneurship. Photo via bauerticker.uh.edu

Hitting headlines this month are innovation news stories from sustainability and education to funding and startup competitions.

In this innovation news roundup, two health-focused startups raise money, the University of Houston earns two pats on the back, a Houston-based former WeWork exec joined the C-suite of a sustainable clothing company, and more.

BrainCheck closes $8 million series A round

BrainCheck has received funding to grow its cognitive assessment platform. Photo via braincheck.com

Houston-based BrainCheck, a cognitive health tech platform closed its $8 million series A funding round. Austin-based S3 Ventures and Chicago-based Tensility Venture Partners co-led the round, and Austin-based True Wealth Ventures and Kansas-based Nueterra Capital also contributed to the round.

BrainCheck's digital platform allows physicians to better assess cognitive function in their patients. The new funds will be used for research and development, including customizing the platform's algorithm for an enhanced patient experience, according to a news release.

"Cognitive healthcare should be an end-to-end solution where problems can be assessed early, and results shared between patients and physicians," says Dr. Yael Katz, co-founder and CEO of BrainCheck, in the release. "By analyzing multiple forms of data, BrainCheck helps physicians create and fine tune personalized interventions. This not only improves outcomes for current patients, but is invaluable to developing management and treatment strategies for future generations."

Former WeWork exec Emily Keeton joins C-suite of a sustainable clothing startup

Goodfair has created a digital thrifting platform. Photo via goodfair.com

After a little over two years at WeWork in leadership positions, Emily Keeton has left the coworking space company to join a Houston startup. Keeton, who was among the founders of Station Houston, is now the chief operating officer at Goodfair, a direct-to-consumer thrift platform based in Houston.

"The rise of fast fashion is contributing to major environmental change," she tells InnovationMap. "Right now, the average American buys 68 new garments a year and wears each one only 7 times. Clothing production is responsible for over 20 percent of all industrial water pollution."

Keeton says she was connected with Goodfair's CEO, Topper Luciani, through the company's lead investor, Paul Bricault of California-based Amplify. Luciani just moved to Houston, and the company also has a warehouse here.

Goodfair sells bundles of "pre-loved" clothes based on size and category at a low price point.

"You know you'll get a medium flannel shirt, but you don't know exactly what color. If you don't like it, you can get a new order for the cost of shipping only," Keeton says. "We have created an entirely new model for this industry, which is an over $14 billion market."

NurseDash raises bridge round as the startup braces for growth

Houston-based NurseDash is the Uber of staffing nursing shifts in medical facilities. Photo via nursedash.com

A growing Houston startup has received bridge funding ahead of opening a larger round. NurseDash, a digital staffing tool for nurses and medical facilities, has received $500,000 from East Coast-based SEI Ventures.

The corporate-backed fund has contributed greatly to higher education institutions, like Capella University, which has a large nursing program.

"Some of the ways we think we can help NurseDash accelerate their growth is getting getting word out to Capella's tens of thousands of alumni and hundreds of employer partners to make sure they are aware of the advantages of the platform, and potentially organizing an educational partnership as well," Taylor Chapman, Houston native and principal at SEI Ventures, tells InnovationMap.

NurseDash, which launched in 2017, now has a presence in 80 facilities on the platform and over 1,000 clinician users in Houston, Austin, and Northeast Ohio.

"We are excited to have SEI join us as a strategic investor and the opportunity that it brings for us to provide enhanced educational opportunities to our clinicians as well as greater exposure the wonderfully talented group that comprises the alumni and nursing students of Cappella University," says CEO and Co-founder Jake Kohl in an email.

University of Houston programs receive recognition

The University of Houston's business school has been recognized for two of its programs. Photo courtesy of University of Houston

The University of Houston's business school has two more feathers to add to its cap.

Bloomberg BusinessWeek named the MBA program at the C. T. Bauer College of Business as among the world's best programs for entrepreneurs. The program tied for ninth in the B- category out of 126 programs surveyed.

"Bauer students indeed reflect the values of our beloved Houston," Professional Programs Associate Dean Leiser Silva says in a news release. "Like our city, they have grit, they are resilient, and they are the bearers of an unparalleled ingenuity. It is in their character to assume calculated risks and be entrepreneurs."

Meanwhile, Bauer's Stimulating Urban Renewal through Entrepreneurship received the 2019 Award of Excellence for Innovation + Talent at the recent University Economic Development Association annual summit. The program creates a partnership between UH students and local entrepreneurs and area business leaders.

"At the heart of the program is experiential learning for our students, along with a commitment to service and civic engagement," says SURE™ founder and director Saleha Khumawala, in a news release.

Capital Factory seeks Texas companies for artificial intelligence challenge

blockchain

Capital Factory is looking for AI companies to compete for $100,000. Getty Images

Austin-based Capital Factory, which has a statewide presence, is looking for startups with artificial intelligence technologies.

The $100,000 Artificial Intelligence Challenge is asking companies to submit their solutions to four key challenges decided by the Army Artificial Intelligence Task Force. The four challenges are: Intelligence support for long-range precision, automated threat recognition for the next-generation combat vehicle, human resources and talent management, and predictive maintenance for military assets.

The competition will conclude on November 12th, at Capital Factory's Defense Innovation Summit. Five technology finalists will be judged by a panel, and one will receive a $100,000 investment that day. The deadline to apply online is October 21.

Work & Mother announces new location

Houston-based Work & Mother is rethinking how new mothers pump in the office. Courtesy of Work & Mother

Houston startup Work & Mother, which runs lactation centers for new moms returning to work, has another location opening. Brookfield Properties announced that Work & Mother has signed a lease for a 949-square-foot space at Three Allen Center at 333 Clay St. in downtown Houston with an expectation top open next summer.

"We are thrilled to partner with Brookfield Properties on this project. We've found that companies aren't equipped to fully address such a private and intimate issue as pumping breast milk in the office," says Abbey Donnell, founder and CEO, in a news release. "It doesn't make sense for every company in a large office tower to take this on individually. Work & Mother is a better economic option for companies in that they reduce their legal risks and create a better working environment, preserving their own office space for their core business."

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."