Two Houston companies will be pitching at SXSW in March hoping to win their categories and take home "Best of Show." Marie Ketring/via sxsw.org

In two months, a couple Houston companies will be packing their bags and headed for Austin, where they will pitch their startups at the 11th annual SXSW Pitch event. SXSW announced the 50 finalists on Wednesday.

A total of six Texas companies — two from Houston and four from Austin — will be presenting to a live audience and panel of judges at the March 9 to 10 competition. There are 10 categories, each with one winner, as well as an overall "Best of Show" winner.

Houston-based Fluidity Technologies will be presenting as its drone controller, FT Aviator, has been named a finalist in the Hyper-Connected Communities category. Fluidity is lead by CEO Scott Parazynski, a former NASA astronaut, pilot, and physician. The FT Aviator has the potential to revolutionize drone technology. The joystick-like controller is based off movement in space, Parazynski says, and is less prone to user error by someone not as well trained in drone operation.

"I've flown aircraft and spacecraft," Parazynski says in an InnovationMap article about the company. "But none allowed for the precision of motion I was looking for. None prevented unintended motion."

The other Houston company selected as a finalist is Zibrio SmartScale, which is in the Health and Wearable category. The company is all about balance. Its product, a smart scale that tracks balance, aims to reduce dangers that come with poor balance — injuries, deaths, and costs from falls. Katharine Forth leads the company as CEO and founder. The company was a member of TMCx's 2015 medical devices cohort.

SXSW's competition this year has expanded to include new categories and has seen an increase in startups.

"We have seen a 42 percent rise in applicants coming out of last year's event, and we couldn't be more thrilled to see such an impressive increase in the value of SXSW Pitch among the tech industry's most innovative startups," says SXSW Pitch Event Producer Chris Valentine in the release. "In addition to the creation of the new AI and blockchain categories, we've also expanded our advisory board to highlight geographic, gender, and racial inclusion – accelerating our desire to represent the world's most innovative and successful leaders in all areas of technology."

It's not just in the finalists that Houston is represented — two advisers are from the Bayou City. Mariam Jacob, of Allergy and Asthma Clinics of Houston, will be a pre-event coach, and Gabriella Rowe, CEO of Station Houston, will be an on-site coach.

These three entrepreneurs have a lot up their sleeves for 2019. Courtesy images

3 Houston innovators to know this week

Who's Who

This week starts in one year and ends in the next, and InnovationMap has three inspiring entrepreneurs to lead you into 2019. All three are behind Houston startups that are planning for big growth in the upcoming year. So, read their stories and get familiar with their names and faces — they aren't going anywhere.

Ben Johnson, founder and CEO of Apartment Butler

Ben Johnson's business idea turned into a growing company making the lives of apartment dwellers easier. Courtesy of Apartment Butler

Ben Johnson has his own master plan. He'd work as an oil and gas banker for a bit, establish himself, get his MBA, and then, when he was in his 40s, would start his own company. He wasn't wrong about his future as an entrepreneur, but he was off by the timeline.

Johnson started Apartment Butler a few years ago when he saw how apartment communities had the potential to provide streamlined access to resident elected services — such as cleaning or pet care. At the same time, apartment communities across the U.S. were looking to beef up their amenities. Now, Apartment Butler is expanding to its third and fourth markets early next year and is looking to provide more services to its users.

Scott Parazynski, CEO of Fluidity Technologies

Scott Parazynski is a accomplished astronaut and surgeon, but he has a new career focus on drone operation. Courtesy of Fluidity

There are Renaissance men and then there's Scott Parazynski. He's has spent 57 days in space, trained as a trauma surgeon, and climbed Mount Everest as a team physician for the Discovery Channel. His latest conquest is designing a drone controller based on movement in space. The device, called the FT Aviator, allows for one-handed piloting of drones and has the potential to affect the way unmanned vehicles are piloted across industries. As the CEO of Fluidity Technologies, he has big plans for what one-handed drone operation can do.

David Grimes, CEO and co-founder of Snap Diligence

David Grimes thought he was creating a useful tool to vet colleagues. Turns out, he made a way for warm connections better than LinkedIn. Courtesy of Snap Diligence

Hell hath no fury like a businessman scorned. When a business partner ended up being a shady miscreant, David Grimes realized there wasn't a digital vetting tool where you can evaluate a potential associate. After thinking on the idea for a while, Grimes found a co-founder and a way to create an algorithm that can take public information and run it against a person. The company he created is called Snap Diligence.

Now, the tool has morphed into something else that's been unexpectedly in demand. Snap Diligence can find business connections through your already-established network of associates. It's this new feature the company is looking to expand in 2019.

Fluidity Technologies' joystick-like device is designed based on movement in space. Courtesy of Fluidity

Houston-based company's device is revolutionizing drone technology across industries

Unmanned with one hand

It's not enough that Scott Parazynski has spent 57 days, 15 hours and 34 minutes in space. Nor is the fact that he's trained as a trauma surgeon. Not even climbing Mount Everest as a team physician for the Discovery Channel could satisfy one of Earth's most talent-blessed residents. Now Parazynski is on course to change multiple industries with his latest invention.

Not surprisingly, the member of the US Astronaut Hall of Fame based his design on movement in space. He wanted to approximate the movement of simultaneously shifting from one place to another, but also changing the body's orientation. In zero gravity, it takes precision and planning, Parazynski says, to do that in the most efficient way possible.

As a member of the Houston Methodist Research Institute, his goal was to create a joystick-like device "that would revolutionize surgical robotics." That is still a target for the technology, but with his own Houston-based company, Fluidity Technologies, Parazynski is first releasing the device as a drone controller known as FT Aviator.

"Mostly because it's an enormously growing marketplace and the barriers are a lot less," he admits.

That's not to say Parazynski is anything less than a world-class expert on the subject of flight.

"I've flown aircraft and spacecraft," says Parazynski. "But none allowed for the precision of motion I was looking for. None prevented unintended motion."

Lifelong passion
He himself has had toy drones for as long as they've been available and purchased his first "serious drones" three or four years ago, around the same time he conceived of FT Aviator.

When he started to research other drone controllers, he realized that most current models aren't too different from relics from the 1930s on display at the Smithsonian.

"There has been zero innovation in flight control," he says.

As opposed to the two-handed controllers that recall 1990s video game systems, FT Aviator only requires the attention of the pilot's dominant hand. This is especially useful to those using drone cameras. Instead of complex machinations that often require multiple launches, the user can simply make adjustments to the camera with his or her other hand.

"It does this incredibly intuitive motion with a drone or computer game or virtual augmented reality," Parazynski says, listing other potential uses for the technology.

It's FT Aviator's natural movement that will one day make Fluidity's core technology a groundbreaker in surgical robotics. Since the da Vinci surgical robot's 2000 FDA approval, the machine has created controversy. In the hands of a well-trained surgeon, it substantially reduces healing time. But there is no approval process for doctors to use it, so disasters in the hands of untrained practitioners have made the news.

By using the simpler mechanism of Parazynski's technology, the learning curve for robotic surgery is far less steep.

"What we want to do is make it so someone with less training can enjoy the same outcomes," Parazynski explains.

Cross-industry innovation
Ideally, one day a doctor in Houston will be able to operate remotely on a patient across the globe. Thanks to the device's tactile feedback, it's a realistic goal.

But Parazynski foresees "dozens of applications" for his invention, which will begin shipping in February. Sandia National Laboratories in New Mexico has already engaged Fluidity, just one on a list of about 50 businesses and government institutions interested to work with the company when it comes onto the marketplace.

"But any good startup will tell you it's about focus," the entrepreneur admits.

That means that for now, he and his team have his eye specifically on controlling drones. Within two weeks of launching a Kickstarter this fall for the business, Fluidity doubled its goal. The FT Aviator has been named a 2019 Innovation Award Honoree at the 2019 Consumer Electronics Show. But Parazynski says he owes much of his success to Houston, his home of a quarter century.

Fluidity is based out of a WeWork coworking space.

"I think it's a really exciting place to have a tech startup" Parazynski says. "It's not yet to the scale of Silicon Valley or even Austin but certainly the innovation that's taking place here warrants a major tech hub."

And thanks to Parazynski's work, that day may be coming sooner rather than later.

Drone on

Courtesy of Fluidity

From surgeries to flying drones, Fluidity's technology will affect several industries.

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CultureMap Emails are Awesome

7+ can't-miss Houston business and innovation events in June 2026

where to be

Editor's note: The FIFA World Cup comes to Houston this month, joined by major energy conferences and a lineup of fan-favorite, recurring events. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.


June 1-4 — CLEANPOWER 2026 Conference and Exhibition

CLEANPOWER unites policymakers, experts, and corporate leaders to solve the challenges that none can solve alone. This must-attend, four-day conference is packed with cutting-edge discussions about wind, solar, storage, and transmission; dealmaking; networking; and fun.

This event begins June 1 at the George R. Brown Convention Center. Register here.

June 2 — Humans of Healthcare

Houston Methodist Center for Innovation will present its quarterly speaker series, Humans of Healthcare. The series will feature a panel of experts who will share about their career paths and discuss the nuances of the health care industry. This month's session will focus on today’s nursing landscape, the industry’s expectations of nurses and what career paths are possible in the field.

The event is Tuesday, June 2, from 5-6:30 p.m. at the Ion. Register here.

June 9 — Greentown Go Make Kickoff

Head to the Ion to celebrate the Greentown Go Make 2026 cohort. The open-innovation program with Shell Catalysts & Technologies and Technip Energies focuses on catalytic solutions for industrial decarbonization and the energy transition. Hear pitches from the founders and network with a select group of startups while enjoying food and drink.

This event is Tuesday, June 9, from 5:30-8 p.m. Register here.

June 9-10 — Texas Brain Economy Summit

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. Expect to hear from leaders of global institutions, including the World Economic Forum, U.S. Chamber of Commerce, McKinsey Health Institute, Global Brain Economy Initiative, Davos Alzheimer’s Collaborative, Business Collaborative for Brain Health (UsAgainstAlzheimer’s), Rice University, Memorial Hermann, MD Anderson and many others. Read InnovationMap's full preview of the event here.

This event begins Tuesday, June 9. Purchase tickets here.

June 10 — MIT Future of Healthcare Technology Forum

The MIT Club of South Texas will host an in-person forum to explore how innovation, government and policy are changing the healthcare industry. The event will feature MIT alumni and Houston healthcare leaders, including Dr. Tim Boone, dean of the Texas A&M School of Engineering Medicine; Cynthia Reinhart-King, chair of bioengineering at Rice University; Dr. Tony Lin, CEO and chairman emeritus of Kelsey-Seybold Clinic; and others.

This event is Wednesday, June 10, from 5:15-8:30 p.m. at the TAMU EnMed Building. Register here.

June 11 — Goals & Gigawatts: Houston Energy & Climate Week The Power of & Kickoff Party

Come watch the Mexico City FIFA opening match while celebrating energy and innovation at the Goals & Gigawatts Kickoff Party. The event will feature food, drinks, and a showcase on Houston Energy & Climate Week. Learn what to expect and how to get involved in HECW before closing the night with a DJ and karaoke.

This event is Thursday, June 11, from 1:30-6:30 p.m. Find more information here.

June 16-17 — Energy Projects Conference & Expo

The Energy Projects Conference & Expo (EPC Show) is the largest event in North America for professionals working at the heart of major energy projects. The essential event for engineering, construction, commissioning, operations and maintenance across multiple energy sectors brings together five leading conferences under one roof. Conference subjects span LNG exporting, hydrogen and ammonia, midstream, petrochem and refining, and sustainable aviation fuels.

This event begins June 16 at George R. Brown Convention Center. Register here.

June 25 – NASA Tech Talk

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing, and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, June 25, from 6-7 p.m. at the Ion. Register here.

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”