Meet 5 of the fastest-growing scaleup companies in Houston

houston innovation awards

These five scaleups stood out to the judges of the 2024 Houston Innovation Awards. Photo via Getty Images

The 2024 Houston Innovation Awards will feature a new category: Scaleup of the Year, which honors a Bayou City company that's seen impressive growth in 2024.

From biotech companies to decarbonization startups, the inaugural finalists have expanded internationally, moved to larger facilities, completed clinical trials and more. Read on to learn more about these fast-growing startups.

Secure your tickets to the 2024 Houston Innovation Awards next Thursday, November 14, at TMC Helix Park.


Cart.com, a unified commerce and logistics solutions provider for B2C and B2B companies

With the acquisition of Amify, Cart.com has expanded its workforce and grown its suite of services. Photo courtesy of Cart.com

Clinching unicorn status with its 2023 series C raise, Cart.com is on a mission to unify commerce across sales and distribution channels and digital and physical capabilities with its omnichannel enterprise-grade software, services and logistics.

Founded in 2020 with nine acquisitions and $759.2 million raised to date, according to Crunchbase, Cart.com's recent achievements includes acquiring Pacsun’s fulfillment operators, brining a 2 million-square-foot facility online, expanding its executive team, and more.

"In the last 12 months, Cart.com has dramatically grown its fulfillment network’s scale and technological capabilities," writes CEO Omail Tariq in his Houston Innovation Awards application.

"We have been laser-focused on improving quality, performance and efficiency at scale while continuing to aggressively grow our customer base, expand our capabilities to customers in new industries and grow our physical presence to new locations," he continues. "Prioritizing our strategic growth initiatives has been critical in the current macroeconomic environment as profitable growth remains paramount for our team."

In 2021, Cart.com moved its headquarters to Austin, with most of the leadership team remaining in Houston. Two years later, the company announced its HQ return to the Bayou City.

"We've found Houston's business and university communities to be incredibly supportive of our efforts and have found the city to be a place that is both easier and more affordable to bring together our global employee population at more regular intervals," Tariq adds in the app.

Coya Therapeutics, a clinical-stage company developing therapies for neurodegenerative, autoimmune, and metabolic diseases

Houston company with revolutionary neurodegenerative disease treatment shares milestones since IPOCoya Therapeutics rang the closing bell at Nasdaq last week, celebrating six months since its IPO, new data from trials, and additions to its team. Photo via LinkedIn

Revolutionary biotech company Coya Therapeutics Inc. (NASDAQ: COYA) may have closed its IPO in January 2023 for more than $15 million, but the company has made some of its most significant strides in the development of its lead product that prevents the further spreading of neurodegenerative diseases this year.

Known as COYA 302, the product uses a unique dual mechanism that is now being developed for the treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease. The company published its phase 1 proof-of-concept study in the peer-reviewed journal Frontiers in Neurology that showed COYA 302's ability to stop clinical progression in ALS at 24 weeks in combination therapy, which helped earn the company a $5 million in strategic investment from the Alzheimer’s Drug Discovery Foundation to continue to develop the product for a planned Phase 2 trial focused on FTD.

Last year the company also added to its C Suite, naming Dr. Arun Swaminathan as chief business officer and Dr. Fred Grossman as president and chief medical officer.

Coya merged with Nicoya Health Inc. and raised $10 million in its series A in 2020.

NanoTech Materials, a chemical manufacturer that integrates novel heat-control technology with thermal insulation, fireproofing, and cool roof coatings to drastically improve efficiency and safety

Growing Houston startup moves into 43,000-square-foot facility amid 'hypergrowth phase'NanoTech Materials celebrated its move into a new facility — a 43,000-square-foot space in Katy, Texas, this week

Mike Francis, co-founder and CEO of NanoTech Materials, told InnovationMap earlier this year that it was in a "hype growth" phase—and meant it.

NanoTech, known for its proprietary Insulative Ceramic ParticleTM (ICP) that uses nanotechnology to optimize energy efficiency and heat control in the built environment, expanded into a new 43,000-square-foot facility this year and tripled its valuation in the last two years, according to its Innovation Awards application. The company also expanded into the Middle East and Singapore and successfully scaled up its NanoTech Cool Roof Coat to commercial markets.

The company closed a $5 million seed round in 2020 and an oversubscribed Series A round last year for $13 million. It was the first company selected for the Houston-based Halliburton Labs in 2021 and joined the Rice Alliance Clean Energy Accelerator in 2023.

Square Robot, an advanced robotics company serving the energy industry and beyond by providing submersible robots for storage tank inspections

Square Robot has a team of 15 in Houston. Photo courtesy\u00a0of Square Robot

Submersible robotics company Square Robot launched its Houston office in 2019 and expanded in the Bayou City this past year.

According to the company's Innovation Award application, the company doubled its fleet of autonomous, submersible robots that service the energy industry, deploying to Malaysia, Vietnam, Thailand, Australia, Kuwait and Saudi Arabia. Its robots are specifically used for storage tank inspections and eliminating the need for humans to enter dangerous and toxic environments.

Square Robot moved to a new, customer-facing Houston facility this year and also developed a new innovative technology that's able to gather phased ultrasonic readings on insulated tank shells while the tank is operational.

The company closed a Series A round in 2018 for $6 million.

Syzygy Plasmonics, a company that's decarbonizing chemical production with a light-powered reactor platform that electrifies the production of hydrogen, syngas, and fuel with reliable, low-cost solutions

Houston climatetech startup selected for inaugural global entrepreneur competitionSyzygy Plasmonics is going to be competing in Gastech's new startup competition. Photo courtesy of Syzygy

Known for the world’s first light-powered reactor cell for industrial chemical reactions, Syzygy Plasmonics began taking orders earlier this year for its Rigel reactor cell after meeting initial performance targets. The cell enables a customer to produce up to five tons of low-carbon hydrogen per day.

The groundbreaking technology earned the company regional, national and global attention. Fast Company magazine placed the company on its energy innovation list. It was also named a finalist for Ernst & Young’s Entrepreneur Of The Year 2024 Gulf South Award and was invited to participate in Gastech's global entrepreneur competition.

The company most recently raised $76 million in a Series C round in 2022.

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Rice biotech studio secures investment from Modi Ventures, adds founder to board

fresh funding

RBL LLC, which supports commercialization for ventures formed at the Rice University Biotech Launch Pad, has secured an investment from Houston-based Modi Ventures.

Additionally, RBL announced that it has named Sahir Ali, founder and general partner of Modi Ventures, to its board of directors.

Modi Ventures invests in biotech companies that are working to advance diagnostics, engineered therapeutics and AI-driven drug discovery. The firm has $134 million under management after closing an oversubscribed round this summer.

RBL launched in 2024 and is based out of Houston’s Texas Medical Center Helix Park. William McKeon, president and CEO of the TMC, previously called the launch of RBL a “critical step forward” for Houston’s life sciences ecosystem.

“RBL is dedicated to building companies focused on pioneering and intelligent bioelectronic therapeutics,” Ali said in a LinkedIn post. “This partnership strengthens the Houston biotech ecosystem and accelerates the transition of groundbreaking lab discoveries into impactful therapies.”

Ali will join board members like managing partner Paul Wotton, Rice bioengineering professor Omid Veiseh, scientist and partner at KdT Ventures Rima Chakrabarti, Rice alum John Jaggers, CEO of Arbor Biotechnologies Devyn Smith, and veteran executive in the life sciences sector James Watson.

Ali has led transformative work and built companies across AI, cloud computing and precision medicine. Ali also serves on the board of directors of the Drug Information Association, which helps to collaborate in drug, device and diagnostics developments.

“This investment by Modi Ventures will be instrumental to RBL’s growth as it reinforces confidence in our venture creation model and accelerates our ability to develop successful biotech startups,” Wotton said in the announcement. "Sahir’s addition to the board will also amplify this collaboration with Modi. His strategic counsel and deep understanding of field-defining technologies will be invaluable as we continue to grow and deliver on our mission.”

New peer-to-peer grocery app launches in Katy with plans to expand

local goods

If computer scientist and mobile applications developer Arfhan Ahmad has his way, his burgeoning Houston-based startup, QuickPantri, will be directly responsible for adding to the definition of what it truly means to be neighborly.

“Fast delivery from next door” — that’s the tagline for Ahmad’s hyperlocal grocery platform, which focuses on solving last-mile access, neighborhood commerce and food affordability.

“I’m passionate about combining technology with real-world problems, especially those that impact working families and underserved communities,” Ahmad says. “I moved to Houston two years ago, and here I realized that grocery stores are far from the neighborhoods.”

Ahmad envisions QuickPantri will help people who need grocery items urgently, sparing them a trip to the store or costly delivery fees by letting them source items directly from their neighbors’ cupboards.

With his new peer-to-peer app, members — especially those tethered to their residence due to disability or immobility or those unable to make grocery runs with children in tow — can simply log on to QuickPantri and purchase grocery items from their own neighbors.

“My initial thought was, 'What if we have an app that allows people to open a grocery store at their own home and sell any essential items to other neighbors?'” Ahmad says. “So, after having this idea in my mind, I asked my neighbors, 'If I sell groceries from my home, would you buy them from me?' And most of them gave me positive responses. After doing some surveys online on the Nextdoor app and Facebook, I started building this app.”

And like a good neighbor, Ahmad launched QuickPantri in his own neighborhood in Katy.

He then looked at scaling, first by securing approvals from Harris County to sell pre-packaged grocery items from his home. The response exceeded his own expectations. In the last two months, Ahmad estimates that he has delivered to 250 homes in the Katy area. Ahmad has seen that most customers use the app in search of late-night snacks and drinks.

“Ninety-five percent of those orders were delivered in 15 to 30 minutes … Our plan is to expand in other high-risk communities and other cities,” Ahmad says.

To date, Ahmad has obtained approvals from Arizona, Utah and Nevada.

He’s in the process of launching version two. Starting September 1, other sellers will be able to join the app and apply to sell goods to their neighbors. Ahmad says he currently has 50 sellers on the waitlist.

Each seller is allotted a potential selling radius of 10 minutes to ensure swift delivery. Also, sellers are required to deliver the goods via bicycle or on foot, making QuickPantri a pollution-free delivery option.

Currently, the app only sells pre-packaged items and sellers are required to show the expiration date in photos. The app utilizes AI to check pricing for goods in the area, and Ahmad says the app typically lists prices lower than what AI predicts.

Outside of geographic reach and number of buyers and sellers, Ahmad also hopes to expand the list of items that can be sold on the app to include clothes, electronics and cleaning supplies.

“We want our seller to be the ultimate source,” Ahmad says.

2 Houston universities excel on 2026 list of best U.S. colleges

Best in Class

Two top-tier Houston universities have been inducted into a new "hall of fame" list of the best colleges in the U.S. for 2026.

Rice University and the University of Houston were both praised in The Princeton Review's "The Best 391 Colleges: 2026 Edition."

Released August 12, the comprehensive guide annually ranks the best universities across 50 categories based on a survey of 170,000 current college students. Survey questions cover topics such as a school's academics and administration, student quality of life, politics, campus life, city life, extracurricular opportunities, and social environment.

The Princeton Review did not numerically rank the schools overall, but it does report the top 25 schools (out of the total 391) for each of the 50 different categories. The report also clarifies that while schools did not pay to be included in the guide, they could pay for a "featured" designation. Neither Houston university paid to be featured on the list.

Rice University, Houston's most prestigious private institution, appeared in the overall 391 best colleges list, and it also appeared in the regional "Best Southwest" list, the "Best Value Colleges" list, and the "Colleges That Create Futures" list. Rice's overall quality and its academic integrity are what students say are its greatest strengths. Students are additionally encouraged to think creatively — and even unconventionally — about how to approach course assignments.

"There's also an outside-the-box thinking when it comes to assessments, like 'the option to make a 30 minute scientific podcast instead of taking the final,' explains one sophomore," the school's profile says. "This isn't unusual for first-years either; one notes that 'instead of doing a bunch of writing and essays, I was tasked with creating...a TED Talk, which really lit a creative flame in me.'"

Rice students can brag about attending a school with the seventh best college newspaper and the 10th best college dorms and quality of life out of all colleges nationwide. The university's financial aid is also the ninth best in the country.

Here's how Rice fared in other Princeton Review rankings:

  • No. 14 – Top 50 Best Value Private Colleges
  • No. 14 – Lots of Race/Class Interaction
  • No. 17 – Best College Radio Station
  • No. 18 – Top 20 Best Value Private Colleges without Financial Aid
  • No. 19 – Best Science Lab Facilities
  • No. 23 – Best-Run Colleges
  • No. 25 – Students Study the Most

Rice has recently earned praise in a separate 2026 ranking of the best universities in the world, and its MBA program scored highly in The Princeton Review's 2025 best business schools list.

University of Houston also appeared in The Princeton Review's "Best Value Colleges," "Best Southwest," "Green Colleges," and "Colleges That Create Futures" lists. Students at this university also benefit from having the No. 1 undergraduate entrepreneurship program in the nation.

"Whether you're in or out-of-state, students consider their school to be 'not very expensive for the quality of education you're getting,' and the constant improvements help 'you feel like your degree is appreciating in value over time along with the school itself," the university's profile says.

Here's how University of Houston performed in other rankings:

  • No. 20 – Students Love Their School Teams
  • No. 21 – Scotch and Soda, Hold the Scotch (this list measured schools based on "the use of hard liquor" as reported by student surveys)
  • No. 22 – Cancel the Keg (this list measured "how widely beer is used" at schools based on student survey results)
  • No. 22 – Pot's Not Hot (this list ranked colleges with the "least marijuana usage based on ratings from real students about the popularity of marijuana on campus")
  • No. 25 – Most Politically Moderate Students
  • No. 42 – Top 50 Best Value Public Colleges
Unfortunately, UH ranked No. 11 in The Princeton Review's ranking of schools where financial aid is "not so great." However, there is plenty else to appreciate about this high performing university.

Other Texas universities included in The Princeton Review are:

  • University of Texas at Austin
  • Southwestern University in Georgetown
  • Texas State University in San Marcos
  • Trinity University in San Antonio
  • Texas A&M University in College Station
  • Angelo State University in San Angelo
  • Baylor University in Waco
  • Texas Christian University in Fort Worth
  • Southern Methodist University in Dallas
  • The University of Texas at Dallas in Richardson
  • University of Dallas in Irving
  • Austin College in Sherman
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This article originally appeared on CultureMap.com.

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