Three Houston companies pitched their energy transition technologies at an international competition. Photo via Getty Images

It's all hands on deck for pioneering technology to advance the energy transition and climatetech, and three companies with a Houston presence just took the national stage to showcase their climate change solutions.

The United Nations' 2021 COP26, hosted by the Net Zero Technology Centre in Glasgow, featured 10 startup organizations from across the globe battling it out to be crowned the Clean Energy Startup Champion.

The Ion Houston nominated five startups to the competition, and three made it to the finals. Syzygy Plasmonics, which is developing a new type of photocatalytic chemical reactor to reduce both cost and emissions for major commodity chemicals, claimed third place in the competition. The other two Ion nominees that pitched were:

  • S2G Energy, an Ion Smart Cities Accelerator participant, and cloud-based Energy Assistant platform that collects data and manages devices from almost any source to capture efficiency opportunities
  • Cemvita Factory, which applies synthetic biology to reverse climate change and transform CO2 into a usable material
"The Ion partnered with Net Zero with the vision to bring innovative and transformative startups out of the North/Central and South American market to the stage in Glasgow," says Jan E. Odegard, executive director of The Ion, in a statement. "We took a look around our own ecosystem both at The Ion and the Ion District and S2G Energy, Syzygy Plasmonics, and Cemvita Factory were easy and obvious nominations, as they were all working towards achieving net zero and are exemplars of startup innovation within our ecosystem."
Australia-based Mineral Carbonation Int'l, focused on carbon transformation, claimed first place and the title of top Clean Energy Startup Champion. PJP Eye, based in Japan and working on commercialised plant-based carbon batteries, came in second.
The second cohort of The Ion Smart and Resilient Cities Accelerator hosted a day full of thought leadership and startup pitches. Photo by Shobeir Ansari, Getty Images

4 startups pitch at virtual demo day for Houston accelerator program

resillience

In light of COVID-19, it is more relevant than ever to discuss and support startups with sustainability and resiliency in mind. At The Ion Smart and Resilient Cities Cohort 2 Demo Day, a virtual audience was reminded of that.

"So, 2020 has certainly been a year of unprecedented uncertainty and change for Houston, for Texas, for our country, and for our world," says Christine Galib, director of the accelerator. "The past few months in particular have been especially difficult as the global pandemic and civil unrest continue to spotlight systemic and structural scars on the face of humanity."

The virtual event was streamed on July 1 and hosted several thought leaders and presenters before concluding with pitches from four of the cohort companies.

"Through it all, and in a virtual world, Cohort 2 startups, the mentors, and our Ion team have been the change we wish to see in the world," Galib continues. "For these startups, failure is simply not an option — and neither is going at it alone."

Earlier this year, Galib announced the second cohort would be focused on solutions for Houston's air quality, water purification, and other cleantech needs. The program, backed by Intel, Microsoft, and TX/RX, launched on Earth Day and commenced shortly after. Cohort 3 is expected later this year.

Here are the four companies that pitched and the problems they are trying to solve.

Re:3D

re:3D was founded just down the street from NASA's Johnson Space Center to address the need for a mid-market 3D printing solution. The Houston-based startup also wanted to create their 3D printer that operates on recycled plastics in order to prevent excess waste.

"Where some see trash, we see opportunity," Charlotte Craff, community liaison at Re:3D says in her presentation.

Re:3D's clients can get their hands on their own Gigabot for less than $10,000, and the printer uses pellets and flakes from recycled plastics —not filament — to print new designs. Clients are also supported by the company with design software and training.

"We can help the city of Houston help meet its climate action and resilient city goals by transforming the way people think about recycling," Craff says about Re:3D's future partnerships with the city.

Water Lens

While two-thirds of the world is covered in water, only 0.7 percent is drinkable. And of that fresh water, 92 percent of it is used in agricultural and industrial settings. This is how Keith Cole, CEO and founder of Water Lens, set the scene for his presentation.

Water Lens, which is based in Houston with a lab located in Austin, wants to solve the problem of cities and countries running out of fresh, drinkable water by equipping huge water-using companies with a water testing tool.

"We've developed a system to let anyone test any water literally anywhere in the world," Cole says, citing clients like ExxonMobil, Shell, and Halliburton.

S2G Energy

S2G Energy, based in Mexico, is focused on optimizing energy management in order to digitize, empower, and unlock potential for cost-saving efforts and technology.

In his pitch, Geronimo Martinez, founder of S2G Energy, points out that restaurants, commercial buildings, and other adjacent industries can save money by implementing energy management solutions that come out of S2G Energy's expertise. In Mexico, Martinez says, clients include the top two restaurant chains that — especially during COVID-19 — need optimization and cost saving now more than ever.

Eigen Control

A refinery's distillation columns are expensive — their fuel use accounts for 50 of operating costs, says Dean Guma, co-founder and CEO of Houston-based Eigen Control.

Guma explains in his pitch how Eigen Control's technology can plug into existing sensors, model networks based on data, and employ the startup's artificial intelligent technology to reduce carbon emissions and save money on operating costs.

The Ion Smart and Resilient Cities Accelerator has selected its next cohort. Courtesy of The Ion

Houston accelerator announces newest cohort to tackle cleantech

Smart cities

As the world celebrated the 50th annual Earth Day on April 22, a Houston innovation organization announced a new group of startups for its accelerator program that will focus on cleantech solutions within the city of Houston and beyond.

The Ion's accelerator, which recently renewed its focus on resiliency, announced its second cohort with six startups that will create solutions for Houston's air quality, water purification, and other cleantech needs.

"Through leveraging the power of our local Ion community, The Ion Smart and Resilient Cities Accelerator is committed to solving challenges Houstonians face every day," says Christine Galib, senior director of accelerator programs at The Ion and the director of the accelerator, in a news release. "We connect participating startups with mentors, partners, and stakeholders, so they gain access to the resources they need to build, validate, and scale their technologies. Together, we are building a safer, smarter, and more accessible city for all Houstonians."

The program is supported by Intel, Microsoft, and TX/RX and has began its programming for the new cohort. The six startups selected for the program are:

  • Houston-based Eigen Control uses machine learning and chemical engineering models to combat rising CO2 emissions. Distillation process plants emit so much CO2 — and Eigen Control's processes are working to change that.
  • Houston-based Annapurna Solutions has cloud-based solutions for hazardous and solid waste management.
  • Mexico City-based S2G Energy focuses on sustainable and optimized solutions for businesses and governments with its energy-management-as-a-service technology.
  • Houston-based re:3D is a 3D-printing nonprofit that is democratizing small-scale manufacturing. Its Gigabot can use recycled and reclaimed materials for more sustainable and affordable production. The company, which has offices in Puerto Rico and Austin, donates a printer to someone making a difference with every 100 printers it sells.
  • Austin-based LifePod Corps is a nonprofit that provides disaster relief through renewable and sustainable technologies built and delivered by military veterans.
  • Houston-based Water Lens has created a real-time water data analytics platform for industries that use a lot of water — like oil and gas, agriculture, power generation, coal mining, and food processing. The technology allows for quicker, more reliable results.

The accelerator's leaders chose its theme for the cohort based on the City of Houston's Resilient Houston Strategy and Climate Action Plan. The program has identified these six startups as movers and shakers within these Smart Cities challenges.

"We are thrilled to collaborate with these startups to further develop Houston as one of America's smartest and most resilient cities," says Gabriella Rowe, executive director of The Ion, in the release. "By leveraging our resources and networks, the accelerator and Cohort 2 improve living conditions for all Houstonians. In this way, we stimulate our local economy with new jobs and economic opportunities."

Last year's inaugural cohort was announced in August and focused on resilience and mobility. After a demo day in December, the cohort continued its work in Houston through 15 pilot programs the startups had with the city. The third cohort is expected to launch toward the end of 2020, but the next theme has not yet been decided.

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Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”