Formerly competitors and collaborators in the space race, Houston and Huntsville, Alabama, are now moving the needle on biotech. Getty Images

Before scientists flocked to Boston and Silicon Valley; a tech boom occured in the American south that served as a defining moment for the United States: the Space Race.

At the time, two cities were the epicenters of mankind's desire to elevate its existence into the stars. Astronauts controlled the path of rockets that were built in Huntsville, Alabama, while radioing back and forth with Mission Control in Houston, Texas.

Today, the two cities are still aligned, but the final frontier is closer to home. Houston and Huntsville are currently flourishing in the scope of biotechnology, using the innovative research of thousands of scientists, academics, and clinicians to further human knowledge

Houston is the home to the world's largest medical center — the Texas Medical Center, or TMC — and an impressive community developing cutting-edge companies ranging from med to biotech. However, Huntsville is hot on its heels.

Turning an infrastructure initially dedicated to aerospace and aeronautical innovation into an emerging bioscience hub, Huntsville boasts around 50 biotech companies and a genomic research institute. The ecosystem has the highest concentration of STEM workers per capita in the country and is rallied around a collaborative research environment that boasts an impressive tech portfolio, including resident companies like Blue Origin, Facebook, and Google, while still managing to embody southern hospitality.

Mirroring the concerted efforts of the past, my Houston-born startup, Van Heron Labs, has recently taken a leap of faith in moving much of their laboratory operations to Huntsville, while many core team members remain in Houston. Being frustrated with the options for available and affordable lab space in Houston, the completely bootstrapped Van Heron Labs decided to stretch one foot into Alabama while the other stays rooted in the TMC ecosystem.

One positive upside to the shift to remote work in light of the COVID-19 pandemic are new opportunities for company employees, investors, and mentors to be physically separated, while collaborating and retaining productivity. These new dynamics of distance have allowed Van Heron Labs to expand their technical operations while maintaining ties to Houston.

VHL has recently moved into the HudsonAlpha Institute for Biotechnology, where they continue to develop their technology surrounding improved culture media, which hasn't changed much since scientists saw the publication of the first Peanuts comic. Recently, VHL has established a collaborative partnership with fellow Huntsville biotech Foresight Biosciences, and the two will be exploring a wealth of industries together.

Despite the distance, VHL still continues heavy involvement in the Houston ecosystem. My co-founder, Alec Santiago, is the current Director of non-profit, Enventure, and uses his experiences of establishing a biotech startup to help prepare the students around him to do the same.

Additionally, VHL currently has 17 interns, including current and former University of Houston students, Rice University graduate students, and even a local physics PhD. VHL has also long been in talks with companies in TMC, where they have established connections dedicated to growth. Ultimately, they hope to bridge the two cities and help give each access to new ideas, resources, funding, and mentorship.

Too often, emerging biotech startups struggle to get off the ground, and a lack of capital limits what could grow to be great ideas. To foster the growth of innovators around the nation several cities are primed to step in and welcome researchers. Institutions within Alabama's biotech ecosystem are leading the movement.

For just $188 a month, biotech startup companies located at HudsonAlpha campus can enjoy their own office space, and access to tailored programming which includes commercial IP assessments, regular investor forums and pitch opportunities, membership in supporting bioscience organizations, discounted laboratory supplies, as well as help with public relations, human relations, finding mentors, capital, and legal help.

VHL has taken full advantage of these opportunities, while maintaining a presence in Houston, and urges others to do the same. The lifting of our nation's innovators as a whole is a positive movement, and one that can increase access to many bright minds. Just as in the space race, working together regardless of geography can offer unlimited potential and may even take us to an entirely new plane.

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Rebecca Vaught is the co-founder of Van Heron Labs.

This week's Houston innovators to know includes Rebecca Vaught of Van Heron Labs, Samantha Lewis of GOOSE Capital, and Camilo Mejia of Enovate Upstream. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: Houston entrepreneurs are like the city itself — resilient. And much like the wildcatters that preceded them, they are self-starters and hard working. This week's roundup of Houston innovators all reflect these attributes — whether they're founding their company amid a global pandemic or rebranding a 15-year-old investing institution.

Rebecca Vaught, co-founder of Van Heron Labs

Entrepreneur hopes to bring microbiology into the future with her Houston-based, pandemic-founded startup

Rebecca Vaught started her biotech company just ahead of COVID-19, but she shares on the Houston Innovators Podcast that it's meant more opportunities than challenges. Photo courtesy of Van Heron Labs

When Rebecca Vaught's accelerator program shutdown due to COVID-19, she didn't let that stop the progress for here fledgling biotech business. In fact, it was a turning point.

"A lot of people probably would have seen that as the stopping point but that was actually the beginning of the company," Vaught says on the Houston Innovators Podcast. "What it allowed us to do was actually establish the lab and do the hard work."

As Vaught says, the biotech company, Van Heron Labs, is what it is thanks to the pandemic — not just in spite of it. Click here to read more and listen to the podcast episode.

Samantha Lewis, director of GOOSE Capital

Samantha Lewis, director of GOOSE Capital, shares how the investment firm has rebranded and is focused on the future. Photo courtesy of GOOSE

A prominent investment group, GOOSE Capital — previously known as GOOSE Society of Texas — has opted for a rebranding to move itself into the future for Seed and Series A investment. Samantha Lewis, director of GOOSE, explains the decision means more than just a new name and upgraded website.

"As for the future of GOOSE Capital, expect great things," she tells InnovationMap. "Our rebranding is one of the many steps we are taking to solidify our position in the Seed and Series A venture scene."

Rather than operating as a fund, the GOOSE Capital model enables its corps of investors comprised of Fortune 500 execs and successful serial entrepreneurs direct access to a portfolio of startups and investment deals. At the same time, GOOSE's portfolio companies are able to receive support from these investors. Click here to read more.

Camilo Mejia, CEO and founder of Enovate Upstream

Houston entrepreneur plans to revolutionize and digitize the energy industry

Camilo Mejia, CEO and founder of Houston-based Enovate Upstream, has big plans for increasing efficiency across the oil and gas sector. Photo courtesy of Enovate

Enovate Upstream announced its new artificial intelligence platform that aims to digitize the oil and gas sector to provide the best efficiency and return on investment at every stage of the supply chain cycle — from drilling and production to completion.

"We see a better future in the oil and gas industry," Mejia shares in an interview with InnovationMap. "Our team worked in various roles in O&G, and we don't think the industry will end up as some people may think. The future will be different and digitized, we are just here to facilitate that transition to give back to the industry that gave us a lot."

The company's proprietary cloud-based ADA AI digital ecosystem is challenging the assumptions of the industry by using new technology powered artificial intelligence to provide historical data with AI to give real-time production forecasting. Thanks to the cloud, users can access the information anywhere in the world. Click here to read more.

Rebecca Vaught started her biotech company just ahead of COVID-19, but she shares on the Houston Innovators Podcast that it's meant more opportunities than challenges. Photo courtesy of Van Heron Labs

Entrepreneur hopes to bring microbiology into the future with her Houston-based, pandemic-founded startup

HOUSTON INNOVATORS PODCAST EPISODE 40

While startups everywhere are struggling to adapt in the tumultuous times of COVID-19, Rebecca Vaught and her company, having launched just ahead of the pandemic, don't actually know any other way of existing.

After watching some of her friends thrive in Houston's life science ecosystem, she knew Houston was the place she wanted to start the company that she'd been envisioning and plotting for years. She took a chance on the city, moved in, and began Enventure's Biodesign accelerator. The program shutdown as COVID-19 spread, much like other programs, but Vaught wasn't going to let that stop her momentum.

"A lot of people probably would have seen that as the stopping point but that was actually the beginning of the company," Vaught says on the Houston Innovators Podcast. "What it allowed us to do was actually establish the lab and do the hard work."

As Vaught says, the biotech company, Van Heron Labs, is what it is thanks to the pandemic — not just in spite of it.

"While it's been challenging, the pandemic — in a lot of ways — is the only thing we've ever known and it's a lot of reason why the company has taken off and been successful," Vaught says on the show.

She runs the company with co-founder Alec Santiago and a team of 17 interns — all located across the country. Vaught herself is currently residing in Huntsville, Alabama, after struggling to find lab space in Houston. However, the relocation has been a blessing in disguise.

"Both ecosystems are extremely unique and both bring something different to the table," she says. "My next mission, through my lived experience, is igniting or uniting the Houston and Huntsville biotech ecosystems."

On the episode, Vaught explains how the two cities — each representing key parts of space exploration history and burgeoning tech scene — complement each other. She also shares her plans for growth and the need to bring microbiology into the future.

Listen to the full interview below — or wherever you get your podcasts — and subscribe for weekly episodes.


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6 exciting Houston startup raises to know from July

fresh funding

Houston startups carried the fundraising momentum of Q1 and Q2 into July with several significant seed funding, Series A and Series B rounds.

From geothermal leaders to medtech innovators, these six Houston companies raised more than a quarter billion dollars last month alone, according to reporting by InnovationMap and our sister site, EnergyCapitalHTX.com.

Did we miss a funding round? Let us know by emailing innoeditor@innovationmap.com.

Altillion

Houston-based startup Altillion has secured $5 million in seed funding to accelerate the commercialization of its proprietary IRIS and ALIX technologies, which convert oilfield-produced water into valuable minerals, the company reported earlier this month.

San Francisco-based EIC Rose Rock and Houston-based Flathead Forge led the round. Altillion says the funding will go toward pilot facilities and commercial deployments as the company looks to scale in the U.S. Continue reading.

Buildforce

The U.S. is grappling with a current shortage of 50,000 electricians, according to the National Electrical Contractors Association. Photo via Unsplash

Houston-based Buildforce, which provides a tech-enabled staff platform geared toward electricians and electrical contractors, closed a $10 million Series A round led by Houston’s Saepio Capital last month.

Other investors in the round include Blue Heron Capital, Revolution’s Rise of the Rest Seed Fund, S3 Ventures and Chicago Ventures.

Buildforce says the funding will help fuel its national expansion and further development of its technology.

The startup, founded in 2019, connects electricians with electrical contractors for commercial and industrial construction projects. Continue reading.

Hephae Energy Technology Corp.

The company develops ultra-high-temperature tools to withstand the heat of geothermal reservoirs. Photo via hephaeet.com

Houston-area startup Hephae Energy Technology Corp. closed a $17.8 million Series A financing round last month to commercialize its geothermal technology.

The round was co-led by Pennsylvania-based Susquehanna Sustainable Investments, which invests in early-stage climatech companies, and Copenhagen-based Underground Ventures, which focuses on geothermal energy startups. Alfa8, Baruch Future Ventures, Centaurus Capital LP, Elemental Impact, Exa Ventures, Future Ventures, Grantham Foundation for the Protection of the Environment, New System Ventures and True North Institute joined the round, along with existing Houston-based investor Nabors Industries. Hephae reports in a news release that the Series A round brings the company's total capital raised to $24.7 million. Continue reading.

TYBR Health

The company's B3 GEL System is designed to protect tendons, ligaments and muscles while they heal from orthopedic surgery. Photo via Unsplash

Houston-based healthtech startup TYBR Health has raised a $30 million Series A round to scale its B3 GEL System, which helps protect tendons from scarring after surgery, the company announced last month.

The round was led by Minneapolis-based Vensana Capital and Cleveland-based Mutual Capital Partners, with participation from Denver-based Neovate Capital Partners and existing investors, according to a news release from the company.

TYBR Health said it plans to use the funding to broaden the B3 GEL System's clinical applications, expand commercialization and conduct studies to evaluate its ability to protect tissue and improve healing outcomes. Continue reading.

Venus Aerospace 

Venus Aerospace has secured funding from Mercury Fund, Lockheed Martin Ventures and others. Photo courtesy Venus Aerospace

Houston-based Venus Aerospace closed a $91 million Series B round last month and plans to scale the production of its hypersonic engine.

The round was led by Houston-based Mercury Fund with participation from Lockheed Martin Ventures, MESH, PEAK6, Draper Associates, Starboard Star Venture Capital, Green Sands Equity and other investors, according to a news release.

The investment comes about a year after Venus completed the first U.S. flight test of its high-thrust rotating detonation rocket engine (RDRE). The engine is expected to enable vehicles to travel four to six times the speed of sound from a conventional runway and is about 15 percent more efficient than traditional alternatives, according to the company. Continue reading.

Quaise Energy

A rendering of a Quaise Energy geothermal plant. Rendering via quaise.com

Houston-based Quaise Energy, a producer of utility-scale geothermal power, closed $134 million in a Series B round last month to advance its “superhot” geothermal power plant.

Climate-focused San Francisco-based investment firm Prelude Ventures led the round, with participation from JERA Co., Japan’s largest power generation company, and Idemitsu Kosan, one of Japan’s largest energy companies. Nearly all existing investors, including cleantech-focused investment firm Safar Partners, participated in the round.

The startup expects more equity and debt deals to close “imminently.” Quaise has raised $230 million since its founding in 2018. Continue reading.

Houston researchers develop dissolvable implant for targeted cancer drug delivery

cancer research

Researchers at Houston Methodist have developed a biodegradable implant that can be used to safely and consistently deliver drug treatments to tumors and then dissolve without the need for further surgery.

The implant is only the size of a grain of rice, but its potential is staggering. The biodegradable nanofibrous drug-eluting seed (b-NDES) works as a reservoir parked inside a soft tumor, where it can slowly release immune-stimulating drugs over time. This overcomes a consistent problem with drugs such as immune checkpoint inhibitors. Normal systemic administration sees comparatively little of the drug making its way to the tumor, with most of it circulating throughout the body. The b-NDES is like deploying a small guerrilla fighting force embedded in enemy territory, doing maximum damage to the entrenched tumor.

"To improve cancer treatment, we're trying to start a fire inside the tumor itself," Corrine Chua, associate professor in the Center for BioNanoengineering at Houston Methodist Research Institute, said in a news release. "By activating immune cells directly within the tumor microenvironment, those cells can then travel throughout the body and seek out cancer wherever it exists. The b-NDES platform was developed to help keep therapeutic drugs concentrated inside tumors while minimizing exposure to healthy tissues.”

Chua co-led the study with Alessandro Grattoni, chair and director of the Center for BioNanoengineering at Houston Methodist Research Institute.

The study included support from the Nancy Owens Breast Cancer Foundation and the National Institutes of Health/National Cancer Institute.

Chau and Grattoni used preclinical models of triple-negative breast cancer, an aggressive form of cancer that is estrogen receptor-negative, progesterone receptor-negative and HER2-negative. Because of the receptor negativity, some popular treatments like tamoxifen and trastuzumab are ineffective. Chemotherapy has been shown to be the best course of action.

The b-NDES implant is deployed alongside radiation drugs. It keeps the drugs focused on the tumor, reducing the amount of harmful side effects typically seen when drugs are circulated more widely in the body. In 60 percent of the models, tumors were eliminated and did not cause side effects beyond the tumor site. Once the drugs have been deployed, the implant breaks down naturally.

While promising, more research will have to be done to expand use to other tumor types.

"Although the study focused on triple-negative breast cancer models, the approach could have broader applications for solid tumors," Grattoni added in the release. "It could potentially be used in cancers where there is a tumor lesion accessible for placement, including pancreatic or lung cancers."

New Houston platform Same Day Reels launches for on-demand content creation

In The Moment

If an event doesn't happen on Instagram, did it even really happen? In today's social media-driven age of branding and audience engagement, the answer increasingly is no.

Houston entrepreneur Karen De Amat is looking to fill the online content creation needs of companies with her new venture, Same Day Reels, which launched in early August. It will serve as a platform to connect companies and brands with talent that can help turn an event into a viral moment as it is happening.

"Events move quickly, and social media moves even faster,” said De Amat. “Same Day Reels was built to help brands capture the moment while it still matters. We are creating a more efficient way for businesses and creators to work together. Brands need content faster, and creators need more opportunities to turn their talent into real work. Same Day Reels brings those needs together.”

The company is focused on adding livestreams and concurrent short video content to "activations, launches, fundraisers, grand openings, conferences, hospitality experiences, and private celebrations." Such content can significantly increase the visibility of a product or brand according to digital marketing brands like Wyzowl, whose data found 63 percent of people in 2026 prefer to learn about new products via short video.

Packages offered by Same Day Reels will include filming, editing, and publishing content within hours of the targeted event.

De Amat says that her content creation platform will be a way to preserve the excitement of events and launches by enshrining them with immediate social media-driven memories.

“Event content is no longer just something you post after the fact,” De Amat said. “It is part of how people experience, remember and share the moment.”

Previously, De Amat is also the founder and CEO of Social Behavior, an influencer marketing company she launched from her home in 2014. It quickly garnered an array of clients and thrust De Amat into the spotlight, including numerous appearances on Fox 26's The Isiah Factor. Influencer Marketing Hub named her one of the top CEOs of influencer marketing companies in Houston in 2025.

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This article originally appeared on CultureMap.com.