This week's roundup of Houston innovators includes Angela Holmes of Mercury Data Science, Ashok Gowda of BioTex, and Rachel Moncton of ClassPass. Courtesy photos

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — data science, consumer tech, and medical device innovation — recently making headlines.

Angela Holmes, chief operating officer of Mercury Data Science

Mercury Data Science has taken a tool it originally developed for COVID-19 research and applied it into new areas of research and innovation. Photo courtesy of MDS

When the pandemic hit, the team at Mercury Data Science knew data was going to have a huge role to play. Last fall, MDS released an AI-driven app designed to help researchers unlock COVID-19-related information tucked into biomedical literature. The app simplified access to data about subjects like genes, proteins, drugs, and diseases.

Now, a year into the coronavirus pandemic, the company is applying this technology to areas like agricultural biotech, in which the platform enables researchers to sift through literature to dig up data about plant genetics, says Angela Holmes, chief operating officer at MDS. The lack of gene-naming standards in the world of plants complicates efforts to search data about plant genetics, she says.

The platform's ability to easily ferret out information about plant genetics "allows companies seeking gene-editing targets to make crops more nutritious and more sustainable as the climate changes to have a rapid way to de-risk their genomic analyses by quickly assessing what is already known versus what is unknown," Holmes says. Click here to read more.

Ashok Gowda, founder and CEO of BioTex

Houston-based BioTex works with medical device and health tech companies from all stages, from R&D to commercialization. Photo via biotexmedical.com

In the process of building a medical device company called Visualase and exiting it to Medtronic for over $100 million, Ashok Gowda learned a lot. And, over the past two decades, he's been sharing that knowledge and expertise of his and his team to medtech companies of all stages at Houston-based BioTex.

"Ultimately we built a nice infrastructure by supporting (the Visualase) spin out," Gowda tells InnovationMap. "And we learned a lot about not just product development, but about commercializing and creating a new market that may not exist. And we had some really good, experienced commercial folks we had hired on the Visualase side. I just think it's a good learning lesson that you can't really teach this stuff — you gotta experience it really to understand." Click here to read more.

Rachel Moncton, vice president of Global Marketing at ClassPass

Rachel Moncton shares why ClassPass tapped Houston as a prime place to expand. Photo courtesy of ClassPass

Rachel Moncton has lived all over the world in her career at fitness and wellness-focused consumer tech company, ClassPass — and her latest assignment has been standing up the company's fourth domestic office right here in Houston, Texas.

On last week's episode of the Houston Innovators Podcast, Moncton shares how Houston as a hub offers the growing company a chance to be a big fish in a small consumer tech pond.

"I get a lot of people saying, 'Houston? That's an interesting choice and not what we'd expect,'" Moncton says. "But that's one of the things we like about it. There's a good startup scene here but not a million different consumer tech companies, so it's nice that we are able to make a bit of a splash." Click here to read more.

Rachel Moncton joins the Houston Innovators Podcast to share why ClassPass chose Houston for its fourth domestic hub and what the consumer tech company has on its horizon for 2021. Photo courtesy of ClassPass

Tech exec shares how she's excited to 'make a splash' in Houston with recent expansion

HOUSTON INNOVATORS PODCAST EPISODE 75

When Rachel Moncton decided she wanted to move back to the United States after years of growing consumer tech company ClassPass internationally, she had no clue where she was going to end up.

The current vice president of marketing had served in various leadership roles for the company, and the powers at be at ClassPass, a consumer-facing tech company that brings together fitness classes and wellness experiences onto one app, decided that Moncton's move would be to spearhead the company's fourth office in Houston.

ClassPass, which was founded in New York City in 2011 before quickly opening its second office in San Francisco. Moncton says a few years ago the company conducted a search for a city that would make for a great expansion and, while Houston was definitely a contender, Missoula, Montana, became the next hub for ClassPass, which has raised over $500 million in venture capital. But, Houston was top of mind for the next expansion.

"When we were thinking about our fourth U.S. office, we wanted something bigger — we're growing quickly and knew we would have to tap into a large talent pool," Moncton says on this week's episode of the Houston Innovators Podcast, noting other elements like Houston's parks, sports teams, culture, universities, and more.

"I get a lot of people saying, 'Houston? That's an interesting choice and not what we'd expect,'" Moncton says. "But that's one of the things we like about it. There's a good startup scene here but not a million different consumer tech companies, so it's nice that we are able to make a bit of a splash."

Last fall, Moncton made her move to Houston to stand up the office virtually, at first, and now the local team is 10 people strong. Currently, ClassPass is looking for its physical space somewhere inside the loop and is hoping to have it open by this summer. Likely, Moncton says, the office will start in a coworking or flexible space that will be able to grow alongside the team.

And speaking of growth, Moncton says ClassPass is still hiring in Houston for roles from sales and finance to customer service and more.

"We are hiring across the board. It's fun for the teams to get to meet people you might not be working with day to day, and it fosters a better sense of empathy and understanding of how the company works," Moncton says. "Even though I lead marketing, it's by no means a marketing hub."

As ClassPass expands its presence, Moncton says she's focused on expanding the company's partners on the app. ClassPass has historically connected users to fitness studios but now is featuring more and more health, wellness, and beauty experiences.

"The technology we've built is to help people find things to book in their city," Moncton says. "There's a lot of (fitness studios) and it can be hard to find what you're looking for. Beauty and wellness are no different."

Moncton shares more about what she's excited about for the future of ClassPass, and how she's experienced Houston so far on the episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


Here's why ClassPass tapped Houston as a prime place to expand. Photo via Getty Images

Why my global tech startup picked Houston for its next location

guest column

Most people know that fitness and wellness leader ClassPass started in New York City. It's less well known that ClassPass has a large office in Missoula, Montana that houses several members of our leadership team, including CEO Fritz Lanman.

In 2017, the ClassPass team spent nine months conducting an intensive nationwide search for a city that matched our mission and values. As a brand focused on supporting an active lifestyle, we wanted a city that offered a connection to the outdoors. One of the most important driving factors in our search was finding a city where we could attract incredible talent to our team. Though we settled on Missoula, Houston was high on the list.

I'm thrilled that four years later, we are finally adding Houston as the fourth US ClassPass office. I have personally relocated to this city and now call myself a Houstonian. Here's five reasons why ClassPass chose Houston for our new US office:

Houston has a welcoming and collaborative culture

Since moving to Houston, every person I have met has been so welcoming. Locally founded tech companies are looking for ways to partner, and accelerators such as Houston Exponential have gone out of their way to make our transition smooth and facilitate introductions within the tech ecosystem. This is a friendly city, and one that encourages the growth of tech companies.

Great sports teams and miles of biking trails

Play is such an important part of the ClassPass culture (one of our values is "play to win"), and Houston is a dynamic place to do just that. With great sports teams, amazing museums, and tons of green space with miles of running and biking trails, there is something for everyone. And particularly in the winter when our colleagues are dealing with huge snow storms in NYC and Montana, it is such a treat to be able to spend time outside.

Self care is an important part of the culture

Locally, ClassPass partners with more than 900 Houston businesses including fitness centers, gyms, spas and beauty salons. In the Houston area, we have seen tremendous usage for both our fitness and wellness offerings, with members booking classes such as a full body strength class at Tropa Z Fitness or a Pilates session at 713 Pilates. Our beauty and wellness offerings are also popular, with people making the time for a sports recovery massage at Serenite Massage, a compression session at Restore Cryotherapy, or a bikini wax at Wink Lash Bar. It's important to us to know we are based in a city where the community embraces self-care, and where we can help local businesses to grow.

The legendary food

You need food to fuel your workouts! The food scene in Houston is incredible, and I am personally delighted to keep exploring and trying takeout from more places (I am currently on a quest for the best breakfast tacos!). Whether it's ordering lunch together once we are all able to be in-person, or going out for a meal after a new milestone is reached, I look forward to sampling the food scene with our new Houston team members.

The large talent pool

Houston is home to universities including Rice University and The University of Houston, and Texas A&M and UT Austin are nearby. With so much feeder talent coming out of local schools, and a reputation as one of the most diverse cities in the US, we are confident that Houston will be a place to recruit for teams across our organization.

Want to join our team? Check out open roles here.

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Rachel Moncton is the vice president of Global Marketing at ClassPass, the leading fitness and wellness membership and a global provider of corporate wellness benefits. She is based in Houston.

ClassPass is expanding into Houston with over 20 new jobs and a local office. Image courtesy of ClassPass

Fitness tech platform expands to Houston and plans to hire

new to hou

When a global technology company focused on fitness and wellness was looking for a city to open their fourth office in the United States, the team wanted a community that was active and full of young professionals. They landed on Houston.

Membership-based fitness and wellness company ClassPass is opening a local office in Houston and is planning on hiring over 20 professionals across departments — from analytics, customer experience, design, and engineering, to marketing, partnerships and product.

Rachel Moncton, vice president of global marketing for ClassPass, has already relocated to Houston to lead the new office.

"Houston is a friendly, community-focused city with a rich talent pool. We are thrilled to contribute to the Houston economy by creating new opportunities for professionals with varying skill sets, and hope to build a local team with a broad range of experiences and backgrounds," says Moncton says in a news release.

Headquartered in New York City, ClassPass's membership and mobile application connects members to fitness and wellness appointments at over 30,000 studios and 11,500 wellness venues. In Houston, ClassPass has over 900 partners.

Currently, the company has 400 employees worldwide with offices in Missoula, Montana, and San Francisco. ClassPass's new hires will work remotely at first, and the organization is hoping to open a physical office later this year.

"It's great to see another Bay Area company expanding to Houston like Nuro, Bill.com, and Homebase," says Harvin Moore, president of Houston Exponential. "ClassPass is already using the HTX Talent jobs board to build its Houston team and we hope to work more with them as they build their presence here."

The app has 900 fitness and wellness partners in Houston already. Image courtesy of ClassPass

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UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.

New Texas Stock Exchange officially begins trading in Dallas

Welcome to Y'all Street

Two-step aside, New York Stock Exchange and Nasdaq. The Dallas-based Texas Stock Exchange, nicknamed Y’all Street, just kicked off live trading with five stocks — and lots of Lone Star ambition.

“The Texas Stock Exchange aims to revitalize competition for [stock] issuers, establish the premier venue for listings, and create a world-class trading platform for all market participants,” the exchange says in a fact sheet.

The exchange — whose Texas-influenced nickname is a nod to New York City’s Wall Street — has collected at least $275 million in investments. The roughly 90 financial backers of TXSE include Bank of America, BlackRock, Charles Schwab, Citadel Securities, Dell Family Office, Fortress, Goldman Sachs, and JPMorgan Chase.

Representatives of TXSE couldn’t be reached for comment. On its website, the exchange calls itself “the most well-capitalized equities exchange to ever be approved” by the U.S. Securities and Exchange Commission (SEC).

Not to be outdone, NYSE has launched Dallas-based NYSE Texas and Nasdaq has expanded its presence in Dallas.

Y’all Street adds to Dallas-Fort Worth’s rising status as a major hub for financial services, with The Wall Street Journal naming North Texas the country’s second biggest financial hub after New York City.

“A homegrown national exchange means more jobs, more investment, and more growth opportunities for businesses and communities across the Lone Star State,” Gabriela von zur Muehlen, senior vice president and chief policy officer at the Texas Association of Business, told The Texas Tribune.

Bulent Temel, an associate professor of practice in economics at the University of Texas at San Antonio, told Texas Standard that TXSE “is going to boost the credibility of the Texas economy.”

Texas’ estimated gross domestic product (GDP), a yardstick for the size of an economy, climbed to a record-setting $2.9 trillion in 2025, making it the state with the second highest GDP after California. DFW’s estimated GDP in 2023 stood at $744.6 billion, eclipsing the GDP of many countries.

“The center of gravity for American capitalism is now headquartered in the Boom Belt,” Abbott proclaimed in April, referring to an 11-state region (including Texas) in the South and Southeast that’s seeing tremendous economic and population growth. “The Texas Stock Exchange is the natural extension of that capitalism. It ensures that capital markets will reflect the quadrant that is driving American growth.”

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This article originally appeared on CultureMap.com.

Orion vehicle manager reflects on Artemis II, looks to 2028 moon mission

Q&A

Humanity is finally headed back to the moon after more than half a century. This year's launch of the Artemis II mission in the Orion spacecraft put four crew members in lunar orbit and tested the new ship developed by Lockheed Martin.

Everything went smoothly, safely returning astronauts home, but there is always room to improve. InnovationMap chatted via email with Orion vehicle manager Branelle Rodriguez, shortly after a talk at The Ion, for insight on how Orion might perform in the future as the next lunar landing approaches in early 2028.

InnovationMap: How satisfied are you with the way Orion operated on this past mission?

Branelle Rodriguez: Orion performed exceptionally well during Artemis II, successfully demonstrating critical spacecraft capabilities, including life support systems, displays and controls, and executing manual piloting operations. Artemis II brought humans back to the moon, achieving key exploration and scientific imagery, while validating systems essential for future Artemis missions.

IM: What is the most important thing you learned about improving Orion for the next mission?

BR: The Artemis II mission provided invaluable insights into crew operations and spacecraft performance in a deep-space environment. With every mission, NASA applies lessons learned to continuously improve Orion’s operations, validate design and ensure mission readiness. Artemis II offered our first opportunity to evaluate several new systems and gain a deeper understanding of what it is like for astronauts to live and work inside the spacecraft. The operational, technical and human factors data collected are being integrated across the program to refine future missions, reduce risk and enhance overall mission success.

IM: How has Orion helped the mission to explore space?

BR: Orion is one of NASA’s foundational elements for human deep space exploration—not only supporting the mission but serving as a core component of it. It is currently the only spacecraft capable of carrying crew on deep space missions and returning them safely to Earth from the high speeds required from the vicinity of the moon. No other spacecraft has the technology to endure the extremes that come with human deep-space travel, such as advanced environmental and life support, navigation, communications, radiation shielding, and the world’s largest ablative heat shield to protect the astronauts during reentry into Earth’s atmosphere. Orion has already taken astronauts to explore space farther than ever before—252,756 miles from Earth— and will carry crews to the moon on future missions to explore the lunar South Pole region. The astronauts’ observations, samples, and data collected on these future missions will expand our understanding of our solar system and home planet.

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This conversation has been edited for brevity and clarity.