Small businesses and startups are likely to hurt — and hurt bad — from COVID-19's affect on the economy. Here are some resources to get support. Photo by Hero Images

It's a trying time for the world, and Houston small businesses and startups have been put in a difficult spot. From having to work remotely or being forced to close or scale back operations due to mandates from the government, entrepreneurs are having to figure out their new normals.

However, organizations have leapt at the chance to help their fellow Houstonians, and a number of resources have appeared to provide aid to startups, from advice and resources to grants.

Editor's note: This article originally ran March 25, 2020, but has been updated and republished with more resources.

The Cannon's CERT Program

The Cannon released information about their Cannon Emergency Response Team Program, and Houston startups can apply online. The multi-week program is intended to provide aid and support for startups and small businesses experiencing a crisis caused by external forces — namely COVID-19 and its repercussions, but also natural disasters, market disruption, legislative actions, civil unrest, fraud, or theft.

Click here to apply and learn more.

The Ion's resource center

The Ion has also rounded up resources for its members and the greater Houston innovation ecosystem. It's available online, and has everything from links to national and local resources and financial assistance information to virtual events.

"While we all try and adjust to this new way of life, The Ion will continue to be a resource to our entrepreneurial community the best way we know how, by connecting our community and providing you with opportunities that you need to be resilient during these unstable times. ... We hope this page serves you well and we promise to keep you all up to date on everything innovation taking place in our community," writes Gaby Rowe, executive director of The Ion.

Rowe has also started a video series of interviews with Houston startups — the videos are also available on the webpage.

Click here to access the resource center.

Houston Exponential's virtual event calendar

Houston Exponential worked quickly to turn their online calendar featuring events across the innovation ecosystem in Houston to helpful virtual events. Anyone can submit an event for consideration.

Click here to find the calendar.

To find InnovationMap's curated list of events for April, click here.

The GHP's Greater Houston Business Recovery Center

The Greater Houston Partnership has released a one-stop shop for business help for companies large and small. The amalgamation combines several national and local options, including relevant information about the Coronavirus Aid, Relief, and Economic Security (CARES) Act.

"We know many Houston companies are hurting and do not have the resources to sustain themselves for weeks without help," said Bob Harvey, president and CEO of the Partnership. "The funds provided through the CARES Act are essential to ensure Houston businesses can meet payroll and cover other expenses during this difficult time. "

Click here to visit the Greater Houston Business Recovery Center page.

Fat Finger's procedure app

In an effort to help businesses organize their response, Houston-based tech company Fat Finger has released a procedure app that is available for free. It offers employee agreements, important protocol checklists, and more.

"Our intention is to help teams of all types operate as safe and effective as possible to overcome what we are all going through," writes James McDonough, founder and CEO of the company.

Click here to learn more about the app here.

Houston PR firm to offer free services

Houston-based Paige PR is offering up $5,000 worth of its services to help out a company affected by COVID-19., which includes media relations, influencer relations, media training, employee communication, content development, social media management, corporate event planning, campaign measurement, brand management, community engagement and crisis communication, according to a news release.

"Paige PR's mission is to empower and help businesses tell their unique stories and amplify their messages," says Paige Donnell, Paige PR's founder and CEO, in the release. "Our team wanted to give back and honor a company making a positive difference, despite these uncertain times. Now is not the time to halt your company's marketing and communication efforts. However, we understand that this may be the only option for some businesses. We're in this together, and all of us at Paige PR look forward to offering our services free of charge to one deserving company."

Click here to learn more and enter your company.

Gener8tor's free 1-week response program

Just like most accelerator programs, cohort schedules and plans have been affected by COVID-19, but one new-to-Houston program is making some lemonade out of the lemons they were served. Gener8tor, along with the Downtown Redevelopment Authority, announced a partnership for one week of virtual programming for small businesses affected by the COVID-19 outbreak. It's free and an extension of the gBETA program, which launched in Houston in January.

Interested entrepreneurs must apply to be enrolled by Friday, May 27. The week of virtual assistence begins March 30 and goes until April 3. Participants will have access to virtual office hours with experts.

"We have seen firsthand the impact that entrepreneurs have on a community and we hope to call on our network of mentors, investors, and partners to support these new Emergency Response Programs," says Joe Kirgues, Co-Founder of gener8tor, in a news release.

Click here to learn more and sign up.

Hello Alice's business center

Houston-based Hello Alice is a great digital resource for startups locally and beyond. The organization recently announced its grant program that will focus on funding minority-founded startups and quickly snapped into action to create a COVID-19 Business Center free for entrepreneurs to use.

Alice is offering emergency grants to businesses affected by COVID-19 and has also gathered other resources like mental health information, tips for running a remote workforce, and more.

Click here to access the business center.

The Small Business Administration's webinars and disaster loans

Startups, nonprofits, and small businesses can apply for an Economic Injury Disaster Loans for up to $2 million. For small businesses, the interest rate is 3.75 percent, and for nonprofits, the interest rate is 2.75 percent. The SBA's Houston chapter is available for help as well.

Click here to learn more about the EIDLs.

Impact Hub Houston's comprehensive list

If this list here isn't exhaustive enough, Impact Hub Houston has gone the extra mile on their blog, creating a comprehensive and updated list of resources for small businesses and startups, as well as for people in general. There is everything from information on small business financial help and online education to tips for parents and health-related resources.

Click here to access the guide.

Here's how to toe the line between being precautious and alarmist when it comes to your company's approach to COVID19, aka the coronavirus. Getty Images

How your company should respond to the coronavirus, according to this Houston expert

Guest column

News stories of COVID19, also known as the coronavirus, are spreading faster than the virus itself — you can't turn on the television or open your web browser without seeing them. The virus' rapidly climbing statistics provide compelling content for today's 24/7 news cycle, but the constant inundation of new information makes it difficult for most of us to discern fact from fiction. Unfortunately, the result is too often fear – whether warranted or not.

The coronavirus and its potential global impact has already weakened an otherwise strong US economy. Now, as the virus threatens to impact everything from the NCAA's March Madness to the 2020 Summer Olympics in Tokyo, organizations are considering how best to respond to their constituents' concerns and communicate their action plans.

In a blog post this week, the social media giant, Twitter, strongly encouraged it's 5,000 employees around the globe to work from home. Other companies are banning non-urgent travel. And amid mounting fears related to the virus, organizers canceled CERAWeek, an annual energy industry conference in Houston, and the cancelation of Austin's SXSW followed. Interestingly, companies that have been demonstrating an abundance of caution are being viewed favorably by the media and general public. So, what should your company be doing?

Establish an action plan

There is no need to panic or overreact — instead, act reasonably and be prepared to react responsibly as circumstances change. Your plan may only involve restricting travel now, but may have to evolve to allow employees to work from home next month.

A company's response to the coronavirus outbreak should be dictated by the nature of its business activities, its geographic areas of operation and reach, and the spread of the virus itself. A manufacturing plant in rural Texas may not have to respond in the same way a hotel in San Francisco might.

Practice cleanliness and common sense

Amid all the noise, it is easy for common sense to give way to hysteria. However, experts agree that the coronavirus is transmitted much like the cold or flu. General cleaning, hand washing, and antiviral hand sanitizers can help prevent the spread of the virus.

Make common sense precautions a part of your plan. Ensure that common areas and restrooms in your workplace are being thoroughly cleaned. Make antiviral soaps and hand sanitizers available to employees and visitors. And most importantly, encourage employees to stay home if they are feeling sick or displaying any symptoms of illness.

Communicate

In any crisis, honest communication helps to quell fear and alleviate uncertainty, so take this opportunity to reach out to your employees. If you've established a plan, share it with them. If you've stocked the supply closet with Clorox wipes, let them know. And if you've yet to formalize a plan, simply assure your employees that you are closely monitoring the situation and that your team is prepared to respond if circumstances in your area or industry change.

Look for opportunity

It sounds distasteful, but it needn't be. 3M, the makers of surgical masks, have announced they will ramp up production to respond to increased demand. 3M didn't manufacture this crisis, but they are responding to it in a positive way.

Moreover, general practitioners and scientists in every media market are being interviewed as subject matter experts on viruses — these doctors probably never anticipated such publicity, but by sharing their expertise, they are providing a useful public service. Consider whether your company can provide a helpful product, service or resource.

The coronavirus isn't the typical business crisis — astute leadership cannot resolve it, nor can ingenuity quickly solve it. But in the coming months, strong leadership and resourcefulness will be needed to proactively plan, effectively respond and ultimately rebound without ever giving into fear.

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Terrie James is the senior corporate communications expert at Paige PR, a Houston-based public relations and marketing agency.

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Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

10+ Houston innovation leaders in the spotlight at SXSW 2026

where to be

Houston's innovation scene will be well represented at South by Southwest (SXSW) this month.

The week-long, Austin-based conference and festival will spotlight some of the Bayou City's leaders in health care, energy, space and more. The event kicks off today, March 12, and runs through March 18. The SXSW Innovation Conference will feature keynotes, workshops, mentoring sessions and more throughout various venues in the city.

Here's who to see and when and where to find them:

March 12

Aileen Allen, venture partner at Mercury Fund

Mentor Session from 4-5:15 p.m. at Hilton Austin Downtown

Allen will host a mentoring session focused on funding, marketing, advertising, PR and the future of work.

March 13

Heath Butler, partner at Mercury Fund

SXSW Pitch-Smart Cities, Transportation, Manufacturing & Logistics from 2:30-3:30 p.m. at the J.W. Marriott

Butler will judge five innovative startups as they pitch their solutions to advance smart cities, enhance transportation systems, modernize manufacturing, transform logistics, and strengthen government infrastructure and civic operations.

Jonathan Cirtain, CEO and president of Axiom Space

The Clock is Ticking for Space - Replacing the ISS from 4-5 p.m. at the J.W. Marriott

Cirtain will discuss Axiom's pursuit of building the world’s first commercial space station.

March 14

Jesse Martinez, founder and CEO of LSA Global

SXSW Pitch-Intelligent Systems, Robotics, & Multisensory Technology from 10-11 a.m. at the J.W. Marriott

Martinez will judge five innovative startups as they pitch their technologies that aim to enhance the way people connect, communicate and share unique life experiences with those around them in a digital ecosystem.

Jennifer Schmitt, head of operations at Rhythm Energy

Powering Texas with Reliable Integrated High-Demand Energy from 10-11 a.m. at Marlow

Schmitt will join a panel to discuss how EirGrid, the state-owned electric power transmission operator in Ireland, is pioneering solutions as the country works toward 80 percent renewable integration by 2030.

Saki Sasagawa, director of business development for JETRO Houston

Now is Japan's Time: Leading the Future with Deep Tech from 10-11 a.m. at the J.W. Marriott

Sasagawa joins a panel that will share real-time insights from diverse perspectives on the forefront of Japan’s deep tech and IP businesses.

March 15

Bosco Lai, CEO and co-founder of Little Place Labs

SXSW Pitch Alumni: Where Are They Now? from 10-11 a.m. at the J.W. Marriott

Lai joins a panel of four former SXSW Pitch winners to share how they leveraged the platform to take their startups to the next level.

Tara Karimi, cofounder and chief science and sustainability officer at Cemvita

South by South America: The Rise of Southern Brazil Tech from 2:30-3:30. p.m. at The Line

Karimi will participate in a panel to discuss how Rio Grande do Sul, Brazil's southernmost state, is attracting elite talent and AI infrastructure and share insights on navigating the next wave of South American tech growth.

March 16

Dr. Pavitra P. Krishnamani, emergency medicine physician at The University of Texas MD Anderson Cancer Center

Viva La Revolution: How the Digital Age is Transforming Wellness from 11:30 a.m.-12:30 p.m. at Hilton Austin Downtown

Krishnamani will discuss the latest advancements and policies that can accelerate the digital age of health care, such as wearables, telehealth and artificial intelligence.

March 18

Charlie Childs, co-founder and CEO of Intero Biosystems

Spinning Out: What It Takes to Build a University Startup from 2:30-3:30 p.m. at The Line

Childs will join founders who spun their companies out of the University of Michigan to share the real story of navigating IP, early capital, team building, market validation and the “valley of death.”

Dr. James Allison, regental chair of immunology and director of The Allison Institute at The University of Texas MD Anderson Cancer Center

Dr. Padmanee Sharma, professor in the Department of Genitourinary Medical Oncology, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center

Beyond Checkpoints: Immunotherapy’s Next Act from 2:30-3:30 p.m. at the J.W. Marriott

Allison and Sharma will sit down with 21-year-old, Stage 4 cancer survivor Sharon Belvin and Time Magazine journalist Alice Park will discuss the future of immunotherapy and what challenges remain.

Last year, Houston startups Little Places Labs and Helix Earth won top prizes in their respective categories at the prestigious SXSW Pitch event, held this year from March 13-14. No Houston startups were named finalists to compete in this year's event.

NASA revamps Artemis moon landing program by modeling it after Apollo

To the moon

NASA is revamping its Artemis moon exploration program to make it more like the fast-paced Apollo program half a century ago, adding an extra practice flight before attempting a high-risk lunar landing with a crew in two years.

The overhaul in the flight lineup came just days after NASA’s new moon rocket returned to its hangar for more repairs, and a safety panel warned the space agency to scale back its overly ambitious goals for humanity’s first lunar landing since 1972.

Artemis II, a lunar fly-around by four astronauts, is off until at least April because of rocket problems.

The follow-up mission, Artemis III, had been targeting a landing near the moon’s south pole by another pair of astronauts in about three years. But with long gaps between flights and concern growing over the readiness of a lunar lander and moonwalking suits, NASA’s new administrator Jared Isaacman announced that mission would instead focus on launching a lunar lander into orbit around Earth in 2027 for docking practice by astronauts flying in an Orion capsule.

The new plan calls for a moon landing — potentially even two moon landings — by astronauts in 2028.

“Everybody agrees. This is the only way forward,” Isaacman said.

The hydrogen fuel leaks and helium flow problems that struck the Space Launch System rocket on the pad at NASA's Kennedy Space Center in February also plagued the first Artemis test flight without a crew in 2022.

Another three-year gap was looming between Artemis II and the moon landing by astronauts as originally envisioned, Isaacman said.

Isaacman stressed that “it should be incredibly obvious” that three years between flights is unacceptable. He'd like to get it down to one year or even less.

Isaacman, a tech billionaire who bought his own trips to orbit and performed the world’s first private spacewalk, took the helm at NASA in December.

During NASA’s storied Apollo program, he said, astronauts’ first flight to the moon was followed by two more missions before Neil Armstrong and Buzz Aldrin landed on the moon. What's more, he added, the Apollo moonshots followed one another in quick succession, just as the earlier Projects Mercury and Gemini had rapid flight rates, sometimes coming just a few months apart.

Twenty-four Apollo astronauts flew to the moon from 1968 through 1972, with 12 of them landing.

“No one at NASA forgot their history books. They knew how to do this," Isaacman said. “Now we're putting it in action.”

To pick up the pace and reduce risk, NASA will standardize its Space Launch System rockets moving forward, Isaacman said. These are the massive rockets that will launch astronauts to the moon aboard Orion capsules. At the same time, Elon Musk's SpaceX and Jeff Bezos' Blue Origin are speeding up their work on the landers needed to get the astronauts from lunar orbit down to the surface.

Isaacman said next year will see an Orion crew rendezvousing in orbit around Earth with SpaceX's Starship, Blue Origin's Blue Moon or both landers. It's similar to the methodical approach that worked so well during Apollo in the late 1960s, he noted. Apollo 8, astronauts' first flight to the moon, was followed by two more missions before Armstrong and Aldrin aimed for the lunar surface.

“We should be getting back to basics and doing what we know works,” he said.

The Aerospace Safety Advisory Panel recommended that NASA revise its objectives for Artemis III “given the demanding mission goals.” It’s urgent the space agency do that, the panel said, if the United States hopes to safely return astronauts to the moon. Isaacman said the revised Artemis flight plan addresses the panel's concerns and is supported by industry and the Trump administration.