The Cannon launched Cannon Connect — an online platform that takes its community of entrepreneurs, investors, and more online — amid the pandemic and plans for growth. Photo courtesy of The Cannon

When the team at The Cannon — a Houston coworking company with three locations across town — was planning an online platform that would connect members across their properties in January, they didn't see a global pandemic enroute to upend how Houstonians work. It did, however, make the need for an online platform all the more relevant.

Now, Cannon Connect has launched to its members — and it comes equipped with virtual networking, job hunting, resources, and more. The whole goal of the platform is to democratize the programming, resources, and culture The Cannon has created.

"Our recognition was that we have a lot of value we can deliver," says Jon Lambert, CEO of The Cannon. "We want to provide the value that we have to entrepreneurs anywhere and everywhere — we don't want to preclude entrepreneurs, investors, advisers, and service providers from being part of what The Cannon is trying to build just because you're not close to one of our facilities."

Cannon Connect acts as a virtual hub for networking, resources, and more. Photo courtesy of The Cannon

A pivot toward a virtual platform isn't a novel idea, Lambert admits, and other Houston organizations have rolled out their platforms — like Houston Exponential's HTX TechList and Sesh Coworking's Inner Circle. However, The Cannon's main goal is replicating the community it has in its locations and creating an online space for that.

"Having a portal is one thing — creating an environment and an experience where people want to spend their time is another," Lambert says, comparing Cannon Connect to social media platforms and how people use them regularly to stay connected to what's going on.

Another differentiating factor is The Cannon is planning to have its platform used by more than just the Houston ecosystem. Lambert says that over the past year, he's talked to around 30 cities from around the world who are interested in The Cannon's concept. The "future-proofed" virtual platform will enable connectivity and consistency as the company grows.

Current members have access to the portal, and new members can opt in for $30 a month. Image courtesy of The Cannon

"If we're really going to create and grow this community, there's not a building that's big enough for every entrepreneur out there, but certainly in a digital environment, we have the ability to pull those folks in," Lambert tells InnovationMap.

While the conversations on physical spaces in these cities has stalled, Lambert says entering into new markets with a digital-first plan has become the new priority.

The online community is made up of a forum section, jobs board, knowledge center, and more. In the future, The Cannon, which recently acquired Houston crowdfunding platform LetsLaunch, will add in a crowdfunding capability to the site. Live streaming events is another tool that's in the works.

Cannon Connect is available to all Cannon coworking members, and online-only registration is $30 a month or $300 a year. The Cannon team is also working on creating a student membership option, which should be available in the near future.

Learn more in The Cannon's promotional video below:

The Cannon is an Entrepreneurial Ecosystemwww.youtube.com

Houston-based Sesh Coworking has launched an online platform so that members can work alongside each other. Photo via seshcoworking.com

Houston coworking company launches online portal to connect members working from home

coworking from home

As the COVID-19 pandemic continued to enforce working from home and social distancing earlier this summer, a Houston coworking company knew they needed to find a way to reach professionals and entrepreneurs digitally.

Sesh Coworking launched its Inner Circle membership this week to be a one-stop shop for business, connection, support, and more for members. Last month, Meredith Wheeler and Maggie Segrich began working on the virtual space after discovering the need for this virtual space from their network.

"We talked to a lot of people," Wheeler tells InnovationMap. "We were constantly asking people, 'what do you need right now?' And the resounding answer was for community and connection."

While Sesh reopened its physical space in Montrose on June 1, not all members were comfortable — or even able — to return to Sesh in person. So, the idea was to bring Sesh's culture and mission to them by taking the company's existing member portal and upgrading it with features like video conferencing, chatrooms, and more.

"It's almost kind of like a new age version of AIM chat. You could see who's online and you can chat with them," Segrich says. "You can work alongside with people."

With these new tech capabilities, Sesh can continue some of its events — like coffee and coworking and other networking and social events — virtually. Segrich and Wheeler also say they will be able to create accountability groups since some members have said that this new way of working makes it hard to focus and get stuff done.

The platform will also enable educational and training-based events, and Sesh has already created a kind of catalogue for resources and materials that come out of these events so that all members can have access to that information, not just the ones that were able to log on for the event.

"With business right now, and Maggie and I are feeling this constantly, it's like everyday is a new pivot — a new turn, twist, or adaptation that we're having to create," Wheeler says. "Sometimes, you know what you need to do and you don't know how to do it, but you need to figure it out fast. So, hopefully by having these resources at the tips of their fingers, our members can make those turns quicker."

A major perk for Sesh and its founders is that, now that they have everything set up and launched, their reach expands much further than their Sesh Loft in Montrose.

"This is not just limited to Houston. This can go, and we hope it goes, nationwide. We've had folks from all over the country on our digital events," Wheeler says. "This could be the silver lining from everything that's happening in 2020 — that our authentic digital connection has a much farther way to travel."

The first 30 members of Sesh Inner Circle can get a monthly membership rate of just $5.99. After that, it's $14.99 a month to sign up. Existing members to the physical space have access to the virtual platform, and virtual members can access special rates on booking space in the Sesh Loft. The launch of Inner Circle has also corresponded with the expansion of Sesh's store of locally sourced products. The store is available at the Sesh Loft or online.

Connect online

Photo via seshcoworking.com

The member portal lets Sesh coworkers have a one-stop shop for virtual and in-person engagement.

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Rice research breakthrough paves the way for advanced disease therapies

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Bioengineers at Rice University have developed a “new construction kit” for building custom sense-and-respond circuits in human cells, representing a major breakthrough in the field of synthetic biology, which could "revolutionize" autoimmune disease and cancer therapeutics.

In a study published in the journal Science, the team focused on phosphorylation, a cellular process in the body in which a phosphate group is added to a protein, signaling a response. In multicellular organisms, phosphorylation-based signaling can involve a multistage, or a cascading-like effect. Rice’s team set out to show that each cycle in a cascade can be treated as an elementary unit, meaning that they can be reassembled in new configurations to form entirely novel pathways linking cellular inputs and outputs.

Previous research on using phosphorylation-based signaling for therapeutic purposes has focused on re-engineering pathways.

“This opens up the signaling circuit design space dramatically,” Caleb Bashor, assistant professor of bioengineering and biosciences and corresponding author on the study, said in a news release. “It turns out, phosphorylation cycles are not just interconnected but interconnectable … Our design strategy enabled us to engineer synthetic phosphorylation circuits that are not only highly tunable but that can also function in parallel with cells’ own processes without impacting their viability or growth rate.”

Bashor is the deputy director for the Rice Synthetic Biology Institute, which launched last year.

The Rice lab's sense-and-respond cellular circuit design is also innovative because phosphorylation occurs rapidly. Thus, the new circuits could potentially be programmed to respond to physiological events in minutes, compared to other methods, which take hours to activate.

Rice’s team successfully tested the circuits for sensitivity and their ability to respond to external signals, such as inflammatory issues. The researchers then used the framework to engineer a cellular circuit that can detect certain factors, control autoimmune flare-ups and reduce immunotherapy-associated toxicity.

“This work brings us a whole lot closer to being able to build ‘smart cells’ that can detect signs of disease and immediately release customizable treatments in response,” Xiaoyu Yang, a graduate student in the Systems, Synthetic and Physical Biology Ph.D. program at Rice who is the lead author on the study, said in a news release.

Ajo-Franklin, a professor of biosciences, bioengineering, chemical and biomolecular engineering and a Cancer Prevention and Research Institute of Texas Scholar, added “the Bashor lab’s work vaults us forward to a new frontier — controlling mammalian cells’ immediate response to change.”

Greentown Labs names new CEO to lead pioneering climate tech incubator

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Houston and Boston climate tech incubator Greentown Labs has named Georgina Campbell Flatter as the organization’s incoming CEO.

Flatter will transition to Greentown from her role as co-founder and executive director of TomorrowNow.org, a global nonprofit that studies and connects next-generation weather and climate technologies with communities most affected by climate change.

“We are at a transformational moment in the energy transition, with an unprecedented opportunity to drive solutions in energy production, sustainability, and climate resilience,” Flatter said in a news release. “Greentown Labs is, and has always been, a home for entrepreneurs and a powerhouse of collaboration and innovation.”

Previously, Flatter worked to launch TomorrowNow out of tomorrow.io, a Boston-based AI-powered weather intelligence and satellite technology company. The organization secured millions in climate philanthropy from partners, including the Gates Foundation, which helped deliver cutting-edge climate solutions to millions of African farmers weekly.

Flatter also spent 10 years at the Massachusetts Institute of Technology (MIT), where she was a senior lecturer and led global initiatives at the intersection of technology and social impact. Her research work includes time at Langer Lab and Sun Catalytix, an MIT – ARPA-E-funded spin-out that focused on energy storage solutions inspired by natural photosynthesis. Flatter is also an Acumen Rockefeller Global Food Systems Fellow and was closely involved with Greentown Labs when it was founded in Boston in 2011, according to the release.

“It’s rare to find an individual who has impressive climate and energy expertise along with nonprofit and entrepreneurial leadership—we’re fortunate Georgie brings all of this and more to Greentown Labs,” Bobby Tudor, Greentown Labs Board Chair and Chairman of the Houston Energy Transition Initiative, said in a news release.

Flatter will collaborate with Kevin Dutt, Greentown’s Interim CEO, and also continue to serve on Greentown’s Board of Directors, which was recently announced in December and contributed to a successful $4 million funding round. She’s also slated to speak at CERAWeek next month.

“In this next chapter, I’m excited to build on our entrepreneurial roots and the strength of our ever-growing communities in Boston and Houston,” Flatter added in a news release. “Together, we will unite entrepreneurs, partners, and resources to tackle frontier challenges and scale breakthrough technologies.”

Greentown also named Naheed Malik its new chief financial officer last month. The announcements come after Greentown’s former CEO and president, Kevin Knobloch, announced that he would step down in July 2024 after less than a year in the role.

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This article originally appeared on our sister site, EnergyCapital.

Houston firm invests $150M in leading 'lab on a chip' medical diagnostics co.

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Houston-based health technology investment firm Hamershlag Private Capital Management Limited (HPCM) announced a $150.15 million venture investment in Patho Care LLC.

Patho Care is a “lab on a chip” medical diagnostics company known for its noninvasive point-of-care testing platforms, such as its Raman spectroscopy-based platform.

Its digital point-of-care testing devices are programmable, mobile, and reusable and can detect current or future respiratory bacterial or viral infections. The company says the technology is more cost-effective and provides results faster than traditional diagnostic methods.

“Patho Care LLC is a distinguished leader in healthcare diagnostics through the utilization of a novel approach with spectroscopy and this investment aligns with HPCM’s strategy of partnering with high-potential companies in dynamic industries,” L. Mychal Jefferson, Chairman of Hamershlag, said in a news release.

The transaction was structured as an acquisition and recapitalization using newly issued common stock and cash, which will work through a newly formed entity, PathoCare Holdings Inc. The deal will also facilitate the repayment of Patho Care LLC's existing financial obligations and settle Patho Care’s outstanding notes, helping ensure the company’s financial readiness, according to the release.

The investment will help Patho Care LLC improve operational efficiencies, broaden its service offerings and continue to innovate in the diagnostic testing space. The companies hope the collaboration will help “unlock new growth opportunities while maintaining the company’s legacy of excellence in an emerging technology,” according to a news release.

“Our commitment to delivering transformative value through innovative investments underscores our confidence in Patho Care’s vision and capabilities,” Jefferson added.