The Cannon launched Cannon Connect — an online platform that takes its community of entrepreneurs, investors, and more online — amid the pandemic and plans for growth. Photo courtesy of The Cannon

When the team at The Cannon — a Houston coworking company with three locations across town — was planning an online platform that would connect members across their properties in January, they didn't see a global pandemic enroute to upend how Houstonians work. It did, however, make the need for an online platform all the more relevant.

Now, Cannon Connect has launched to its members — and it comes equipped with virtual networking, job hunting, resources, and more. The whole goal of the platform is to democratize the programming, resources, and culture The Cannon has created.

"Our recognition was that we have a lot of value we can deliver," says Jon Lambert, CEO of The Cannon. "We want to provide the value that we have to entrepreneurs anywhere and everywhere — we don't want to preclude entrepreneurs, investors, advisers, and service providers from being part of what The Cannon is trying to build just because you're not close to one of our facilities."

Cannon Connect acts as a virtual hub for networking, resources, and more. Photo courtesy of The Cannon

A pivot toward a virtual platform isn't a novel idea, Lambert admits, and other Houston organizations have rolled out their platforms — like Houston Exponential's HTX TechList and Sesh Coworking's Inner Circle. However, The Cannon's main goal is replicating the community it has in its locations and creating an online space for that.

"Having a portal is one thing — creating an environment and an experience where people want to spend their time is another," Lambert says, comparing Cannon Connect to social media platforms and how people use them regularly to stay connected to what's going on.

Another differentiating factor is The Cannon is planning to have its platform used by more than just the Houston ecosystem. Lambert says that over the past year, he's talked to around 30 cities from around the world who are interested in The Cannon's concept. The "future-proofed" virtual platform will enable connectivity and consistency as the company grows.

Current members have access to the portal, and new members can opt in for $30 a month. Image courtesy of The Cannon

"If we're really going to create and grow this community, there's not a building that's big enough for every entrepreneur out there, but certainly in a digital environment, we have the ability to pull those folks in," Lambert tells InnovationMap.

While the conversations on physical spaces in these cities has stalled, Lambert says entering into new markets with a digital-first plan has become the new priority.

The online community is made up of a forum section, jobs board, knowledge center, and more. In the future, The Cannon, which recently acquired Houston crowdfunding platform LetsLaunch, will add in a crowdfunding capability to the site. Live streaming events is another tool that's in the works.

Cannon Connect is available to all Cannon coworking members, and online-only registration is $30 a month or $300 a year. The Cannon team is also working on creating a student membership option, which should be available in the near future.

Learn more in The Cannon's promotional video below:

The Cannon is an Entrepreneurial Ecosystemwww.youtube.com

Houston-based Sesh Coworking has launched an online platform so that members can work alongside each other. Photo via seshcoworking.com

Houston coworking company launches online portal to connect members working from home

coworking from home

As the COVID-19 pandemic continued to enforce working from home and social distancing earlier this summer, a Houston coworking company knew they needed to find a way to reach professionals and entrepreneurs digitally.

Sesh Coworking launched its Inner Circle membership this week to be a one-stop shop for business, connection, support, and more for members. Last month, Meredith Wheeler and Maggie Segrich began working on the virtual space after discovering the need for this virtual space from their network.

"We talked to a lot of people," Wheeler tells InnovationMap. "We were constantly asking people, 'what do you need right now?' And the resounding answer was for community and connection."

While Sesh reopened its physical space in Montrose on June 1, not all members were comfortable — or even able — to return to Sesh in person. So, the idea was to bring Sesh's culture and mission to them by taking the company's existing member portal and upgrading it with features like video conferencing, chatrooms, and more.

"It's almost kind of like a new age version of AIM chat. You could see who's online and you can chat with them," Segrich says. "You can work alongside with people."

With these new tech capabilities, Sesh can continue some of its events — like coffee and coworking and other networking and social events — virtually. Segrich and Wheeler also say they will be able to create accountability groups since some members have said that this new way of working makes it hard to focus and get stuff done.

The platform will also enable educational and training-based events, and Sesh has already created a kind of catalogue for resources and materials that come out of these events so that all members can have access to that information, not just the ones that were able to log on for the event.

"With business right now, and Maggie and I are feeling this constantly, it's like everyday is a new pivot — a new turn, twist, or adaptation that we're having to create," Wheeler says. "Sometimes, you know what you need to do and you don't know how to do it, but you need to figure it out fast. So, hopefully by having these resources at the tips of their fingers, our members can make those turns quicker."

A major perk for Sesh and its founders is that, now that they have everything set up and launched, their reach expands much further than their Sesh Loft in Montrose.

"This is not just limited to Houston. This can go, and we hope it goes, nationwide. We've had folks from all over the country on our digital events," Wheeler says. "This could be the silver lining from everything that's happening in 2020 — that our authentic digital connection has a much farther way to travel."

The first 30 members of Sesh Inner Circle can get a monthly membership rate of just $5.99. After that, it's $14.99 a month to sign up. Existing members to the physical space have access to the virtual platform, and virtual members can access special rates on booking space in the Sesh Loft. The launch of Inner Circle has also corresponded with the expansion of Sesh's store of locally sourced products. The store is available at the Sesh Loft or online.

Connect online

Photo via seshcoworking.com

The member portal lets Sesh coworkers have a one-stop shop for virtual and in-person engagement.

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Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”